• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.7
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• pp.1749-1756
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• 2014

Knowledge about protein subcellular localization provides important information about protein function. This paper improves a label power-set multi-label classification for the accurate prediction of subcellular localization of proteins which simultaneously exist at multiple subcellular locations. Among multi-label classification methods, label power-set method can effectively model the correlation between subcellular locations of proteins performing certain biological function. With constrained optimization, this paper calculates combination weights which are used in the linear combination representation of a multi-label by other multi-labels. Using these weights, the prediction probabilities of multi-labels are combined to give final prediction results. Experimental results on human protein dataset show that the proposed method achieves higher performance than other prediction methods for protein subcellular localization. This shows that the proposed method can successfully enrich the prediction probability of multi-labels by exploiting the overlapping information between multi-labels.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.03a
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• pp.226-234
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• 2008

Grain design has always been a vital and integral part of Solid Rocket Motor(SRM) design. Basing on the design objectives set by the system designer, the SRM designer has many options available for selecting the Grain configuration. Many of the available configurations may fulfill the required parameters of volumetric loading fraction, web fraction & Length to diameter ratios and produce internal ballistic results that may be in accordance to the design objectives. However, for any given set of design objectives, it is deemed necessary that best possible configuration be selected, designed and optimized. Hence optimal results of all applicable configurations are vital to be attained in order to compare and finalize the design that will produce most efficient performance. Generally the engineers pay attention and have skills on a specific grain configuration. The designing methodologies and computer codes available usually focus on single grain configuration may it be Star, Wagon Wheel or slotted tube. Hardly one can find a software or a design methodology where all such configurations can be worked on jointly and not only adequate designs be found but optimal solutions reached by applying an optimization method to find final design best suited for any design objective. In the present work design requirements have been set, grain configurations have been selected and their designing has been conducted. The internal ballistic parameters have been calculated and after finding the preliminary design solutions, the optimal solutions have been found. In doing so, software has been developed comprising of computer programs for designing the 2D grains including Star, Wagon Wheel and Slotted Tube configurations. The optimization toolbox of Matlab Fmincon has been used for getting optimal solutions. The affects of all the independent geometric design variables on the optimized solutions have been analyzed. Based on results attained from Optimization Method, an in depth comparison of Grain Configurations and analysis of performance prediction outputs have been conducted to come to conclusion as to which grain configuration is ideal for the current design requirement under study.

• Journal of the Architectural Institute of Korea Structure & Construction
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• v.35 no.9
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• pp.143-150
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• 2019

The purpose of this study was to propose how to determine the setting time related to the determination of the surface finish working time of the concrete using a Durometer, which is used as a rubber hardness meter. Two different types of Durometer were used to measure the setting time of the concrete. High flowing concrete with 40% of water to binder ratio was fabricated maintaining $600{\pm}100mm$ of slump flow. The test results indicated that the application of the Durometer resulted in a high correlation with the penetration resistance tester in both mortar and concrete. When measuring the setting time of the concrete, with properly used with Durometer, evaluation of the setting time of the concrete can be available. Therefore, it is thought that the measurement of the final set of the durometer C type can be useful to decide the limit time of the finishing operation and the time of the rejuvenation of the curing process by measuring the finishing set at 40 HD in the case of the initial set and 10 HD in the case of D type.

• Investigative Magnetic Resonance Imaging
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• v.25 no.1
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• pp.10-22
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• 2021

Purpose: To overcome the difficulty in building a large data set with a high-quality in medical imaging, a concept of 'blended-transfer learning' (BTL) using a combination of both source data and target data is proposed for the target task. Materials and Methods: Source and target tasks were defined as training of the source and target networks to reconstruct cardiac CINE images from undersampled data, respectively. In transfer learning (TL), the entire neural network (NN) or some parts of the NN after conducting a source task using an open data set was adopted in the target network as the initial network to improve the learning speed and the performance of the target task. Using BTL, an NN effectively learned the target data while preserving knowledge from the source data to the maximum extent possible. The ratio of the source data to the target data was reduced stepwise from 1 in the initial stage to 0 in the final stage. Results: NN that performed BTL showed an improved performance compared to those that performed TL or standalone learning (SL). Generalization of NN was also better achieved. The learning curve was evaluated using normalized mean square error (NMSE) of reconstructed images for both target data and source data. BTL reduced the learning time by 1.25 to 100 times and provided better image quality. Its NMSE was 3% to 8% lower than with SL. Conclusion: The NN that performed the proposed BTL showed the best performance in terms of learning speed and learning curve. It also showed the highest reconstructed-image quality with the lowest NMSE for the test data set. Thus, BTL is an effective way of learning for NNs in the medical-imaging domain where both quality and quantity of data are always limited.

• Annals of Hepato-Biliary-Pancreatic Surgery
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• v.27 no.2
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• pp.195-200
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• 2023

Backgrounds/Aims: We aimed to build a machine learning tool to help predict low-grade intraductal papillary mucinous neoplasms (IPMNs) in order to avoid unnecessary surgical resection. IPMNs are precursors to pancreatic cancer. Surgical resection remains the only recognized treatment for IPMNs yet carries some risks of morbidity and potential mortality. Existing clinical guidelines are imperfect in distinguishing low-risk cysts from high-risk cysts that warrant resection. Methods: We built a linear support vector machine (SVM) learning model using a prospectively maintained surgical database of patients with resected IPMNs. Input variables included 18 demographic, clinical, and imaging characteristics. The outcome variable was the presence of low-grade or high-grade IPMN based on post-operative pathology results. Data were divided into a training/validation set and a testing set at a ratio of 4:1. Receiver operating characteristics analysis was used to assess classification performance. Results: A total of 575 patients with resected IPMNs were identified. Of them, 53.4% had low-grade disease on final pathology. After classifier training and testing, a linear SVM-based model (IPMN-LEARN) was applied on the validation set. It achieved an accuracy of 77.4%, with a positive predictive value of 83%, a specificity of 72%, and a sensitivity of 83% in predicting low-grade disease in patients with IPMN. The model predicted low-grade lesions with an area under the curve of 0.82. Conclusions: A linear SVM learning model can identify low-grade IPMNs with good sensitivity and specificity. It may be used as a complement to existing guidelines to identify patients who could avoid unnecessary surgical resection.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.42
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• pp.163-186
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• 2009

On April 11, 1980, the "United Nations on Contracts for the International Sale of Goods" ("CISG") was prepared by the United Nations Commission on International Trade Law (UNCITRAL) and approved by a diplomatic conference in Vienna providing uniform law for international sales of goods. It took effect as of March 1, 2005, in Korea. It is set forth on the seller's remedies for breach by the buyer Section III (Art. 61 - 65) under the CISG. In this study, the focus is only on the seller's notice fixing additional final period for performance (Art. 63) and the right to avoid the contract (Art. 64), with examination on some relevant foreign arbitral awards rendered by the ICC and the CIETAC together. Article 63 provides that the seller may fix an additional period of time for reasonable length for performance by the buyer of his obligation. It was found from the above arbitral awards that the concept of 'reasonable length' should be decided on a case-by-case basis, given the specific circumstances in the case [Art. 63(1)]. It is provided that unless the seller has received a notice that he will not perform within the period so fixed, the seller may not, during that period, resort to any remedy for breach of contract in accordance with Article 63(2). Article 64(1) provides the means and grounds for avoidance of the contract, which can be avoided 1) when the breach of the buyer amounts to a fundamental breach of contract, or 2) when the additional period of time is fixed by the seller, unless the buyer declares that he will not perform so within the period of fixed time. As we examined in the above arbitral awards, it was held that the contract is avoided when the seller sends the final notice stating that he will avoid the contract, after the expiration of the additional period of time fixed by the seller in the ICC award. On the contrary, it was held that the contract should be deemed to be avoided exactly when the expiration of additional period noted in the avoidance notice is elapsed in the CIETAC award. Article 64(2) sets time limits for avoidance.

• Journal of The Korean Association For Science Education
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• v.10 no.1
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• pp.1-8
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• 1990

Mechanical CAI Program was developed for university science student The program was mainly aimed for individual study. The program was written in BASIC and construct 130s flams. This project was supproted by Ministry of Education research fund. Summary of this study is as follows. 1. The program consisted of main, pretest, tutorial, final, and several other routines for program control. 2. This program written in BASIC. 3. 20 flames for pretest routine, 90 flames for tutorial routine, 20 flames for final test routine were developed. 4. The expected rate of achivement for final test was set 80%. 5. Average mark of final test was 70.2 point through the all course of program. This means that program was constructed of well.

• Proceedings of the National Institute of Ecology of the Republic of Korea
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• v.2 no.4
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• pp.229-234
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• 2021

Iris dichotoma Pall. found on Daechung Island in Korea has been designated as an endangered species. To aid in conservation efforts of this species, this study investigated its germination characteristics and seed dormancy type. Four sets of seeds were incubated at different temperatures (4/1℃, 15/6℃, 20/10℃, and 25/15℃). One set of seeds was cold stratified (4 weeks at 4/1℃). The final germination rate and mean germination time showed that the optimal germination temperature was 25/15℃. Final germination rates were ~70%, showing no significant difference among temperature treatments. However, mean germination time were significantly different among all temperature treatments except for 4/1℃. Mean germination time for seeds with temperature treatments of 15/6℃, 20/10℃, and 25/15℃ were 3.2, 2.1, and 1.5 weeks, respectively. At 25/15℃, the mean germination time was half of that at 15/6℃. Seeds of I. dichotoma had fully developed embryos at the time of dispersal. No additional growth of the embryo was observed. Cold stratification did not affect the final germination rate or the mean germination time. This study shows that seeds of I. dichotoma have no physiological or morphological dormancy, unlike other members of the Iris genus known to have seed dormancy that needs a relatively high incubation temperature (≥25/15℃) for mass propagation to occur. These results will be useful for understanding ecophysiological mechanisms related to the species' habitat. They are also useful for mass propagation of I. dichotoma for the purpose of conserving this endangered species.

• Journal of computational fluids engineering
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• v.13 no.4
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• pp.50-57
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• 2008

The prediction of hydrate pellet decomposition characteristics is required to design the regasification process of GTS (gas to solid) technology, which is considered as an economic alternative for LNG technology to transport natural gas produced from small and stranded gas wells. Mathematical model based on the conservation principles, the phase equilibrium relation, equation of gas state and phase change kinetics was set up and numerical solution procedure employing volume averaged fixed grid formulation and extended enthalpy method are implemented. Initially, porous methane hydrate pellet is at uniform temperature and pressure within hydrate stable region. The pressure starts to decrease with a fixed rate down to the final pressure and is kept constant afterwards while the bounding surface of pellet is heated by convection. The predicted convective heat and mass transfer accompanied by the decomposed gas flow through hydrate/ice solid matrix is reported focused on the comparison of spherical and cylindrical pellets having the same effective radius.

• Proceedings of the Korean Fiber Society Conference
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• 2003.04a
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• pp.335-336
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• 2003

The synthesis of poly(trimethylene terephthalate) (PTT), whose application is being expanded very rapidly to new apparel and carpet materials, was investigated by melt condensation polymerization using 1,3-propanediol (PDO) and terephthalic acid (TPA). No catalyst was used in the 1st step reaction (esterification), but tetrabutyl titanate(TBT) was used as a polyesterification catalyst ranging from 25 to 75 ppm based on the weight of TPA used in the 2nd step reaction (polyesterification). The molar ratio of PDO to TPA was set as 2.2:1. The effect of reaction conditions on the color and intrinsic viscosity of the final product was investigated. (omitted)