• 한국전자파학회논문지
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• 제14권8호
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• pp.855-862
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• 2003

본 논문에서 제안하는 안테나는 기존 내장형 안테나의 일종인 PIFA의 단점으로 협대역 문제를 해결하기 위하여, 복사 소자와 접지면 사이에 단락판을 위치시키는 변형된 안테나 형태인 PIFA(Planar Inverted-FAntenna) 구조를 제안하였다. 또한 보다 넓은 대역폭을 가지도록 방사 패치에 톱니모양의 perturbation을 주었다. 제안된 방식으로 단말기에 내장형으로 사용하기 위하여 안테나의 높이(h=0.015λ)를 최소한으로 하여 원하는 대역폭(5.2 %)을 얻었다. slim형으로 하기 위해 안테나의 특성을 급전위치(Yf, Zf), 단락 스트립(Short plate)의 위치 (Zs), 폭 (Ws), perturbation폭(w), 길이(d), 단락 스트립 높이(h), 유전율 변화($\varepsilon$$_{r}$)가 안테나에 어떤 변화를 미치는지를 조사하였다. 또한 기존 PIFA 안테나와의 대역을 비교하고, 제안된 패턴을 H, E plane으로 나타내었다. 논문의 객관성을 입증하기 위하여 FIM(Finite Integration Method) 방식에 기반인 MWS(Microwave Studio) 소프트웨어를 이용하여 Simulation 하였으며, 각각의 구조 파라미터 변화에 따른 안테나 특성을 분석하였다. 그리고 실제 제작한 안테나의 실험결과와 비교하여 증명한 결과, 제안된 방식의 PIFA 안테나 실용화가 가능성을 확인하였다..

• 동국한의학연구소논문집
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• 제6권2호
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• pp.167-190
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• 1998

최근 뇌졸중 예후에 관한 연구 경향을 살펴보면 방사선 소견에 예후인자를 살펴보는 방법과, 방사선 소견을 배제한 환자의 상태, 즉 의식이나 인지, 지각, 운동, 언어기능, 대소변 장애 등의 여부와 예후와의 상관관계를 연구하는 방법으로 크게 나누어 볼 수 있다. 전자의 경우는 비교적 객관적인 검토가 가능하지만, 후자의 경우는 연구방법에 있어 어려움이 있었다. 이에 저자는 후자의 방법으로 어떠한 요인들이 뇌졸증의 예후에 영향을 미치는지와, 그 중 가장 영향력 있는 요인이 무엇인지 밝히고자 다음과 같은 통계연구를 하였다. 연구대상은 동국인천한방병원 내과에 일원한 환자 중 뇌졸중 증상발현 48시간 이내에 입원하였으며, 4주간의 추적검사가 가능하였고, 방사선 검사에서 뇌혈관 질환으로 판단된 환자 32명이었다. 연구방법은 입원 시 각 환자의 임상기록지에 기능평가방법의 하나인 FIM, NIH scale, CNS 점수를 기록하고 그 각각의 sub-item 중에서 의식, 인지, 지각, 운동, 언어기능과 대소변 장애에 해당하는 항목을 골라 4주후 MBI로 평가한 기능회복도와의 상관관계를 살펴보았다. 또 각 항목 중에서 가장 영향력 있는 요인을 알아보기 위하여 다중회귀분석을 이용하였고, FIM, NIH scale, CNS의 총점을 다중회귀 분석하여 어느 기능 평가도가 예후에 가장 많은 영향을 미쳤는지도 알아보았다. 의식, 인지, 지각, 운동, 언어, 대소변 항목에 해당하는 FIM, NIH scale, CNS의 각 sub-item에서 점수별로 상, 중, 하위의 군을 나누어 4주후 MBI 평균점수를 살펴본 결과 모두 항목에서 유의성 있는 차이를 보여 이러한 요인들이 예후에 영향을 미친것을 알 수 있었다. 또 MBI 점수의 독립성을 기준으로 해서 5군으로 나누어 각 Sub-item과의 상관성을 살펴본 결과 의식과 지각기능 중 Lim-ataxia 항목을 제외한 나머지 항목에서는 통계적으로 유의성이 있는 것으로 나타났다. 각 Sub-item을 다중회귀 분석한 결과 인지기능이 예후에 가장 큰 영항을 미쳤으며, 지각기능 중 sensory항목과 대변장애가 다음으로 영향을 미쳤다. FIM, NIH scale, CNS의 총점을 나누어 다중회귀 분석하여 본 결과 가장 영향력 있는 평가도는 FIM이었고, 다음은 CNS였다.

• 대한의생명과학회지
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• 제18권2호
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• pp.146-151
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• 2012

Urinary tract infection (UTI) is one of the most common bacterial infections and is predominantly caused by uropathogenic Escherichia coli (UPEC). UPEC strains generally possess several genes encoding virulent factors, which are mostly adhesins, toxins, bacteriocin and siderophores. E. coli is composed of four main phylogenetic group (A, B1, B2, D) and virulent extra-intestinal strains mainly belong to groups B2 and D. Prescription of ciprofloxacin, a kind of fluoroquinolone group antibiotics, is increasing now a days, but resistance to this drug is also increasing. A total of 188 strains of E. coli were collected. Thirteen strains were collected from healthy students in 2011 and 175 strains from patients with urinary tract infection in 2010. Virulence factor genes (papC, fimG/H, sfaD/E, hlyA, cnf1, and usp) were amplified by polymerase chain reaction (PCR) methods for phylogenetic group (A, B1, B2, D) detection. Ciprofloxacin susceptibility test was performed by disk diffusion method. The identified virulence factors (VFs), phylogenetic groups and ciprofloxacin resistance in 13 E. coli strains isolated from healthy students were papC (15.4%), fimG/H (76.9%), sfaD/E (30.8%), hlyA (23.1%), cnf1 (23.1%), usp (7.7%), phylogenetic group A (23%), B1 (8%), B2 (46%), D (23%) and ciprofloxacin resistance (7.7%), while those of in 175 E. coli strains isolated from patients with UTI were papC (41.1%), fimG/H (92.5%), sfaD/E (30.3%), hlyA (10.3%), cnf1 (30.3%), usp (27.4%), phylogenetic group A (9.1%), B1 (5.1%), B2 (60.6%), D (25.1%) and ciprofloxacin resistance (29.7%). In this study, 10 out of 13 E. coli strains (76.9%) from healthy students were found to possess more than one virulence factor associated with adhesion. In addition, one E. coli strain isolated from healthy students who had never been infected with UPEC showed ciprofloxacin resistance. According to these results between the virulence factors and phylogenetic groups it was closely associated, and UPEC strains isolated from patients showed high level of ciprofloxacin resistance.

• 대한의생명과학회지
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• 제28권2호
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• pp.127-136
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• 2022

Uropathogenic Escherichia coli (UPEC) is main causative agent of urinary tract infections. They are classified based on various types of O antigen. UPEC strains commonly possess many genes encoding virulece-associated factors. E. coli strains are generally divided into four main phylogenetic groups. The virulence factor (VF) profiles of UPEC are related with their O-serogroups in each strains. A total of 681 strains of UPEC clinical isolates were collected from Korean healthcare facility (1989: 123 strains and 2010-2014: 558 strains). The UPEC clinical isolates were analyzed by polymerase chain reaction (PCR) methods. A total of 14 O-serotypes (O1, O2, O4, O6, O7, O8, O15, O16, O18, O21, O22, O25, O75 and O83), 6 virulence factors (papC, fimG/H, sfaD/E, hly1, cnf1 and usp) and phylogenetic groups were identified. The most prevalent O-serogroups were O6 (11.1%) in 1989 UPEC strains and O25 (21.0%) in 2010-2014 UPEC strains. The identified VFs, phylogenetic groups in 1989 UPEC strains and 2010-2014 UPEC strains were fimG/H and B2 group. In this study, O6 serotype was revealed the close relationships with VFs. Also, the distribution of prevalence O-serogroups of UPEC has been changed from O6 to O25 and virulence of UPEC strains was increased during past twenty-one years.

• Journal of Veterinary Science
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• 제23권1호
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• pp.9.1-9.11
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• 2022

Background: Escherichia coli, which causes subclinical or clinical mastitis in cattle, is responsible for transmitting antimicrobial resistance via human consumption of raw milk or raw milk products. Objectives: The objective of this study was to investigate the molecular characteristics of 183 E. coli from bulk tank milk of five different dairy factories in Korea. Methods: The molecular characteristics of E. coli such as serogroup, virulence, antimicrobial resistance, and integron genes were detected using polymerase chain reaction and antimicrobial susceptibility were tested using the disk diffusion test. Results: In the distribution of phylogenetic groups, group D was the most prevalent (59.6%) and followed by group B1 (25.1%). The most predominant serogroup was O173 (15.3%), and a total of 46 different serotypes were detected. The virulence gene found most often was fimH (73.2%), and stx1, fimH, incC, fyuA, and iutA genes were significantly higher in isolates of phylogenetic group B1 compared to phylogenetic groups A, B2, and D (p < 0.05). Among 64 E. coli isolates that showed resistance to at least one antimicrobial, the highest resistance rate was observed for tetracyclines (37.5%). All 18 integron-positive E. coli carried the integron class I (int1) gene, and three different gene cassette arrangements, dfrA12+aadA2 (2 isolates), aac(6')-Ib3+aac(6')-Ib-cr+aadA4 (2 isolates), and dfrA17+aadA5 (1 isolate) were detected. Conclusions: These data suggest that the E. coli from bulk tank milk can be an indicator for dissemination of antimicrobial resistance and virulence factors via cross-contamination.

• Bulletin of the Korean Chemical Society
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• 제27권8호
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• pp.1127-1132
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• 2006

A new salicylate-selective electrode based on the complex N,N'-1,4-butylene bis(3-methyl salicylidene iminato) copper(II) as the membrane carrier was developed. The electrode exhibits a good Nernstian slope of 59.1 ${\pm}$ 1.0 mV/decade and a linear range of $1.0\;{\times}\;10^{-6}$-1.0 M for salicylate. The limit of detection was $5.0\;{\times}\;10^{-7}$ M. It has a fast response time 10 s and can be used for more than three months. The selective coefficients were determined by the fixed interference method (FIM) and could be used in the pH range 4.5-10.5. It was employed as an indicator electrode for direct determination of salicylate in pharmaceutical samples.

• 천문학논총
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• 제18권1호
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• pp.87-95
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• 2003

FIMS (Far-ultraviolet IMaging Spectrograph) is the main payload of STSAT-1 satellite which was successfully launched on September 27, 2003. The optical system of FIMS consists of two sets of parabolic cylinder mirror, slit, ellipsoidal reflection grating, and baffle system. We designed two types of baffle system for the FIMS: FOV baffle and order baffle. FOV baffle in the mirror house controls the field of view, and the order baffle in the vacuum box blocks the rays reflected rays by different orders.

• Journal of Astronomy and Space Sciences
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• 제19권4호
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• pp.273-282
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• 2002

과학위성 1호의 주탑재체인 원자외선 분광기의 검출기 전자부에 대한 특성을 분석하였다. FIMS (Far-ultraviolet Imaging Spectrograph)는 교차 지연선 양극을 가진 MCP(micro-channel plate)를 사용하여 입사된 원자외선 광자의 위치를 검출한다. MCP에 입사하는 광자는 MCP을 통해 전자형태로 변환되고 증폭된다. 증폭된 전하운의 중심은 양분되어 연결된 지연선을 통해 양단으로 나가게 되고, 지연선의 양단에서 전하운의 도착시간 차이를 구하여 입사된 광자의 위치를 판독한다. FIMS의 경우 2개의 MCP 검출기를 갖고 있으며, 각각 25mm$\times$25mm의 유효 크기를 갖고있다. 또 신호처리계는 1채널의 신호처리 회로계를 통해 2개의 검출기에 대한 영상검출이 가능하도록 함으로써 신호처리계의 복잡성을 피하고 아울러 전력과 무게 비용을 줄였다. 이 시스템을 통해 높은 시간 및 공간 분해능(<$35{\times}75$ps FWHM)을 얻었으며, 6W 이하의 저전력 시스템을 구현하였다.

• Agricultural and Biosystems Engineering
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• 제4권2호
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• pp.50-57
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• 2003

This study was conducted to develop software which provides automatic site-specific field data acquisition, data processing, data mapping and management for precision agriculture. The developed software supports acquisition and processing of both digital and analog data streams. The architecture was object-oriented and each component in the architecture was developed as a separate class. In precision agriculture research, the laborious task of manual ground-truth data collection will be avoided using the developed software. In addition, gathering high-density data eliminates the need for interpolation of values for un-sampled areas. This software shows good potential for expansion and compatibility for variable-rate-application (VRA). The FIM (Field Information Management) computer program provides the user with an easy-to-follow process for field information management for precision agriculture.

• 한국환경과학회지
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• 제3권3호
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• pp.263-271
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• 1994

A detachment of biofilm was investigated in an inverse fluidized bed biofilm reactor(IFRBR). The biofilm thickness, 5 and the bioparticle density, Pm were decreased by the increase of Reynolds number, Re and the decrease of biomass concentration, h. The correlations were expressed as $\delta$=6l.6+16.33$b_c$-0.004Re and Ppd=0.3+0.027$b_c$- 2.93x$l0^{-5}$ no by multiple linear regression analysis method. Specific substrate removal rate, q was derived by F/M ratio and biofilm thickness as q=0.44.+0.82F/M-5.Ix10$-4^{$\delta$}$. Specific biofilm detachment rate, bds was influenced by FIM ratio and Reynolds number as $b_{ds}$=-0.26+0.26F/M+ 2.17$\times$$10^{-4}$Re. Specific biofilm deachment rate in an IFBBR was higher than that in a FBRR(fluidized bed biofilm reactor) because of the friction between air bubble and the bioparticles.