• 제목/요약/키워드: Filtration pressure

검색결과 356건 처리시간 0.026초

고혈압 동물에서 혈압변동과 적혈구변형능의 상관성 (Relationship between Blood Pressure Changes and Erythrocyte Deformability in Hypertensive Rats)

  • 고광호;이명걸;김낙두;조윤성;권석윤;윤재순
    • 약학회지
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    • 제31권5호
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    • pp.308-314
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    • 1987
  • In cardiovascular disease the flow adaptation of erythrocytes can be affected by reduced shear stresses and metabolic influences on red cell fluidity as a consequence of tissue hypoxia. In addition there are indications that risk factors of cardiovascular diseases are able to decrease the intrinsic red cell deformability. Erythrocyte deformability was studied by the filtration technique of Reid et al. to investigate the relationship between blood pressure chances and erythrocyte deformability. In this experiment normotensive rats, spontaneously and DOCA-salt treated hypertensive rats were used. Erythrocyte deformability was significantly reduced by blood pressure elevation in hypertensive rats but was not fully recovered by normalization of blood pressure after antihypertensive drug treatment. Therefore other factors than blood pressure may be involved in erythrocyte deformability reduction during blood pressure elevation.

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모듈형 이동식 물생산 시스템 운전 성능 및 자연 유기물 제거 거동 평가 (Evaluation of the performance and the removal characteristics of natural organic matter in a modular mobile water production system)

  • 황유훈;양필제;송지민;홍민지;최창형;고석오;김도군
    • 상하수도학회지
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    • 제32권1호
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    • pp.55-65
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    • 2018
  • It is necessary to develop a mobile water production system in order to provide stable water supply in case of disasters such as floods or earthquakes. In this study, we developed a modular mobile water production system capable of producing water for various uses such as domestic water and drinking water while improving applicability in various raw water sources. The water production system consists of three stages of filtration (sand filtration - activated carbon filtration - pressure filtration) to produce domestic water and an additional reverse osmosis process to produce drinking water. In laboratory and field experiments, the domestic water production system showed excellent treatment efficiency for particulate matter, but showed limitations in the treatment of dissolved substances such as dissolved organic matter. In addition, ultraviolet irradiation was considered as additional disinfection step, because it does not form precipitates of manganese oxides after disinfection. Reverse osmosis process was added to increase the removal efficiency of dissolved substances and the treated water satisfied drinking water quality standards. Fluorescence analysis of dissolved organic matter showed that the fulvic acid-like substances in raw water was successfully removed in the reverse osmosis process. The mobile water production system developed in this study is expected to be used not only in water supply in case of disaster, but also widely used in islands and rural area.

Shadow mask 여과 모듈을 이용한 슬러지 농축 특성 (Sludge Thickening Performance of the Filtration Bio-reactor Equipped with Shadow Mask Filter Module)

  • 정용준;권구호;민경석
    • 한국물환경학회지
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    • 제21권1호
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    • pp.29-33
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    • 2005
  • In order to recycle the waste material and to develop the thickening unit of waste activated sludge from wastewater treatment facilities, the filtration bio-reactor equipped with a shadow mask filter module was employed for this work from which the operating properties and parameters were drawn. The sludge thickening and filtration unit is made of cylindrical acryl tank(12cm i.d. ${\times}$ 58cm height: working volume of 6L), where the flat-sheet type of shadow mask filter module(pore size: 220~250um, opening area: 34.8~39.6%) was installed and the effluent was withdrawn from the effluent port at the lowest point of the reactor, and the filtration was performed only by the hydraulic pressure. For evaluating the operating performance of this reactor, some parameters such as the solid-liquid separation of different biomass concentrations, the water quality of filtrate, the aeration cleaning time and the cleaning effect were investigated. Depending on the MLSS concentrations, the different time to withdraw 3L of filtrate was required in which the longer filtration time was necessary for the higher MLSS concentrations caused by the thicker formation of cake layer: 40 minutes for 5,000 mg/L, 70 minutes for 10,000 mg/L and 100 minutes for 15,000 mg/L, where the concentrations of SS were 8.9, 6.7 and 6.5 mg/L, respectively. Under the same operating conditions (the intensity of aeration cleaning: 80 L/min, MLSS: 10,000 mg/L), the proper aeration cleaning time was revealed 30 seconds, and the stable formation of cake layer was in the range of 10 to 15 minutes. Therefore, the shadow mask considered as a waste material can be of use as a filter material for the sludge thickening system.

Improvement of Virus Safety of an Antihemophilc Factor IX by Virus Filtration Process

  • Kim, In-Seop;Choi, Yong-Woon;Kang, Yong;Sung, Hark-Mo;Sohn, Ki-Whan;Kim, Yong-Sung
    • Journal of Microbiology and Biotechnology
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    • 제18권7호
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    • pp.1317-1325
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    • 2008
  • Viral safety is an important prerequisite for clinical preparations of plasma-derived pharmaceuticals. One potential way to increase the safety of therapeutic biological products is the use of a virus-retentive filter. In order to increase the viral safety of human antihemophilic factor IX, particularly in regard to non-enveloped viruses, a virus removal process using a polyvinylidene fluoride membrane filter (Viresolve NFP) has been optimized. The most critical factor affecting the filtration efficiency was operating pH and the optimum pH was 6 or 7. Flow rate increased with increasing operating pressure and temperature. Recovery yield in the optimized production-scale process was 96%. No substantial changes were observed in the physical and biochemical characteristics of the filtered factor IX in comparison with those before filtration. A 47-mm disk membrane filter was used to simulate the process performance of the production-scale cartridges and to test if it could remove several experimental model viruses for human pathogenic viruses, including human hepatitis A virus (HAV), porcine parvovirus (PPV), murine encephalomyocarditis virus (EMCV), human immunodeficiency virus type 1 (HIV), bovine viral diarrhea virus (BVDV), and bovine herpes virus (BHV). Non-enveloped viruses (HAV, PPV, and EMCV) as well as enveloped viruses (HIV, BVDV, and BHV) were completely removed during filtration. The log reduction factors achieved were $\geq$6.12 for HAV, $\geq$4.28 for PPV, $\geq$5.33 for EMCV, $\geq$5.51 for HIV, $\geq$5.17 for BVDV, and $\geq$5.75 for BHV. These results indicate that the virus filtration process successfully improved the viral safety of factor IX.

세라믹 분리막의 분산형 용수공급 시스템 적용을 위한 전처리 연계공정의 고플럭스 평가 (Evaluation of High Flux Combined with Pretreatment Process for Application of Decentralized Water Supply System with Ceramic Membrane)

  • 강준석;박서경;이정은;강소연;이정준;쿠엔 보;김성수;김한승
    • 한국수처리학회지
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    • 제26권6호
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    • pp.61-72
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    • 2018
  • In this study, applicability of the decentralized water supply system were investigated by the high flux evaluation using ceramic membrane with combined pretreatment process. A) filtration process increased the transmembrane pressure of 1.4 kPa and 89.5 kPa on 2 and $5m^3/m^2{\cdot}d$ of filtration flux, respectively, the physical backwashing recovery rate were less than 28.6%. The (B) Coag./Floc. - Sedi. combined process with 4 mg / L of A-PAC showed that the transmembrane pressure increased to within 6 kPa, the physical backwashing recovery rate was over 37.9 % higher than (A) Filtration process. (C) Coag./Floc. combined process showed an increase of transmembrane pressure compared with (B) Coag./Floc. - Sedi. combined process, physical backwashing recovery rate was over 84%. As a result of the membrane fouling analysis using the resistance in series model, the combined pretreatment process showed that the cake resistance (Rc) was more than 92% at membrane filtration flux of $2m^3/m^2{\cdot}d$. In the (C) Coag./Floc. combined process, cake resistance(Rc) was over 86% on high flux conditions. The coagulation floc contained in influent was removed by the membrane, and the cake layer formed with the removed floc was identified as reversible fouling resistance which could be recovered by physical backwashing. The decentralized water supply system, which has the limitation of site area and installation space, is considered to could be operation of high flux of ceramic membrane by applying (C) Coag./Floc. combined process without sedimentation process.

UF와 디스크필터를 전처리시설로 이용한 역삼투압해수담수설비의 평가 (Evaluation of Seawater Reverse Osmosis Desalination System with UF and Disk Filter as Pre-Treatment)

  • 양근모;임동훈;김준하;정형호
    • 대한기계학회논문집 C: 기술과 교육
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    • 제1권1호
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    • pp.59-68
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    • 2013
  • 본 연구에서는 한외여과막과 역삼투압막으로 이루어진 해수담수화장치를 구성하였다. 해수를 취수하여 디스크필터와 한외여과막을 이용한 전처리설비를 통과시켜 생산한 전처리수의 $SDI_{15}$와 탁도를 측정하여 역삼투압해수담수설비에 적합함을 밝혔다. 역삼투압해수담수설비의 부산물인 브라인을 전처리수와 혼합하여 역삼투압해수담수설비의 입구농도를 변화시켰다. 농도 변화실험에서, 해수농도가 역삼투압해수담수설비의 성능에 끼치는 영향을 실험으로 구하였다. 염배제율, 회수율, 생산수의 수질은 입구농도에 따라 많은 변화가 있었으며, 에너지소비량도 입구농도에 거의 선형적으로 상승하는 것을 실험으로 구하였다.