• Title/Summary/Keyword: Filling time

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Improved Radiochemical Yields, Reliability and Improvement of Domestic $^{18}F$-FDG Auto Synthesizer (국산 $^{18}F$-FDG Auto Sysnthesizer의 수율 향상과 성능 개선)

  • Park, Jun-Hyung;Im, Ki-Seop;Lee, Hong-Jin;Jeong, Kyung-Il;Lee, Byung-Chul;Lee, In-Won
    • The Korean Journal of Nuclear Medicine Technology
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    • v.13 no.3
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    • pp.147-151
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    • 2009
  • Purpose: 2-[$^{18}F$]Fluoro-2-deoxy-D-glucose ([$^{18}F$]FDG) particularly plays as a important role in Positron Emission Tomography (PET) imaging in nuclear medicine. Domestic [$^{18}F$]FDG auto synthesizers are installed in Seoul National University Bundang Hospital (SNUBH) at June 2008, these modules were known that it's synthetic yields were guaranteed in average $45{\pm}5%$ so far. To improve yields and convenience of domestic [$^{18}F$]FDG auto synthesizer, numerous trials in reaction time, base concentration, pressure and temperature were performed to increase [$^{18}F$]FDG yields. Materials and Methods: Several synthetic factors (temperature, time and pressure) and shortcoming were corrected based on many evaporation test. Syringe dispensing of tetra-butylammonium bicarbonate (TBAB) was replaced with micro pipette to prepare tetrabutyl ammonium fluoride salt ([$^{18}F$]TBAF). Troublesome refill of liquid nitrogen every 2 hours which was used to protect vacuum system was changed to charcoal cartridge, base guard filter. To monitor the volume of delivered $[^{18}O]OH_2$ from cyclotron by surveillance camera, we set up the volumetric vial on the cover of the module. In addition to, the recovery vial was added in [$^{18}F$]FDG production system to recover [$^{18}F$]FDG loss due to the leak of valve ($V_{13,14}$) in [$^{18}F$]FDG purification process. Results: When we used micro pipette for adding TBAB ($30\;{\mu}L$ in 12% $H_2O$ in acetonitrile), this quantitative dispensation has enabled to improve $5.5{\pm}1.7%$ residual fluorine-18 activity in fluorine separation cartridge compared to syringe adding. Besides, the synthetic yields of [$^{18}F$]FDG has increased $58{\pm}2.6%$ (n=19), $58{\pm}2.9%$ (n=14), $60%{\pm}2.5%$ (n=17) for 3 months. The life cycle of charcoal cartridge and base vacuum was 3 months prior to filling liquid nitrogen every 2 hours and additional side separator can prevent pump corrosion by organic solvent. After setting of volumetric indicator vial, the operator can easily monitor the total volume of irradiated $[^{18}O]OH_2$ from cyclotron. The recovery vial can be used for the stabilizer when an irregular [$^{18}F$]FDG loss was generated by the leak of valves ($V_{13,14}$). Conclusions: We has optimized appropriate synthetic conditions (temperature, time, pressure) in domestic [$^{18}F$]FDG auto synthesizer. In addition to, the remodeling with several accessories improve yields of domestic [$^{18}F$]FDG auto synthesizer with reliable reproducibility.

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$\sqrt{s}$- Observational Procedure for Consolidation Analysis (압밀해석을 위한 $\sqrt{s}$- 예측기법)

  • 정성교;최호광
    • Geotechnical Engineering
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    • v.14 no.2
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    • pp.41-54
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    • 1998
  • Predictions of consolidation settlement and time must be always erroneous because of heterogeneity of soil media. errors associated with the measurement of soil parameters, drawback of consolidation theories and so on. When filling is done on compressible soils, the observational procedure is a useful means in practice of evaluating the final consolidation settlement and time. However, the existing observational procedures including some disadvantages such as the difficulty of ending the linearity in the settlement curves, the unavoidable personal error, and so on. A new observational procedure($\sqrt{s}$ method) is suggested here for the consolidation analysis in field. As the results of applying the $\sqrt{s}$ method with other methods to two field data. the fecal settlements predicted by the s method as well as by the Asaoka'$\sqrt{s}$ method agreed well with the measured values. However, results obtained from the hyperbolic method(Tan, 1991) were always overestimated. and there happened many cases not to be predicted by the Hoshino's method. In the settlement curve from the $\sqrt{s}$method, the linearity between 60 and 90 eye of the average degree of consolidation is shown. and then the possibility of a personal error seems to be unusual. The final consolidation times(at $U_{95}$) predicted by the $\sqrt{s}$ method agreed well with the measured ones. but the ones by Asaoka and Tan(1996) methods were very much underestimated or overestimated. where $U_{95}$, is the average degree of consolidation of 95%. The big errors of these two methods seem to result from unconsidering the effect of stage construction.

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Effect of Early Waterproof on Color Stability and Translucency Change of Glass-ionomer Cement (초기 방습이 글래스아이오노머 시멘트의 색안정성 및 투명도 변화에 미치는 영향)

  • Jeong, Seon-Wa;Kim, Sun-Hun;Oh, Won-Mann
    • Restorative Dentistry and Endodontics
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    • v.19 no.1
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    • pp.124-134
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    • 1994
  • The shade of restorative materials is very important for successful restoration esthetically harmonized with the natural tooth. The purpose of this study was to evaluate the color stability and the opacity change of conventional chemical setting and visible light curing glass-ionomer cements for restorative esthetic filling. Specimens of each brand (GC Fuji II and Fuji II LC) were uniformly prepared and divided into three groups: In group l(control group), the specimens received no surface treatment; in group 2, the specimens were coated with varnish and the excess gently blown off; and in group 3. the specimens were coated with light-cured bonding resin and irradiated by a visible light curing unit for 20 seconds on both sides. All specimens were stored in distilled water at $37^{\circ}C$ and checked after for 24 hours. 2 months. 4 months, 6 months. and 8 months. The color characteristics($L^*,\;a^*,\;b^*$) and the opacity(Y%) of all the samples were measured by a spectrocolorimeter and the total color differences(${\Delta}E^*$) and opacity changes(${\Delta}Y%$) were computed. The following results were obtained : 1. The total tolor differences in all groups increased with time. 2. The total color differences of the LC groups after immersion for 8 months in distilled water at $37^{\circ}C$ were lower than those of GC groups(p<0.01), and the total color differences of the varnish or the light-cured bonding resin coated groups were lower than those of the control group with glass-ionomer cements which had no surface treatment(p<0.01). 3. In all groups the translucency decreased with time. 4. In the control group and the varnish coating group. the opacity changes of the GC groups were lower than those of the LC groups(p<0.01) and in the light-cured bonding resin coated group, there was no significant difference between the GC group and the LC group. 5. The opacity changes of the varnish or the light-cured bonding resin coated groups were lower than those of the control group(p<0.01). These results suggest that color change and opacity of conventional chemical setting and light cured glass-ionomer cement were increased with time, and the color changes and the opacity changes of a control group after immersion for 8 months in distilled water at $37^{\circ}C$ were greater than those of the varnish or the light-cured bonding resin coated groups.

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Considerations of Permeability of Converter Slag for Recycling (재활용을 위한 전로슬래그의 투수성 고찰 (I))

  • 이광찬;이문수
    • Journal of the Korean Geotechnical Society
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    • v.15 no.4
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    • pp.69-83
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    • 1999
  • The permeability of converter slag, replacing material of sand mat on improving soft clay foundation, was evaluated in the laboratory. The effects of grain size, flow water time and aging were investigated using sea and fresh water. In the case of converter slag submerged with fresh water, the coefficients of permeability in A and B samples less than 10 mm grain sizes were measured as $6.52\times10^{-2}cm\; per\; sec\; and\; 5.99\times10^{-1}/cm$ per sec respectively, while they were $1.88\times10^{-2}/cm\; per\; sec,\; 3.86\times10^{-1}/cm$ per sec respectively under sea water condition. Also, the condition of turbulent flow may exit and was experimentally identified from the relationship between hydraulic gradient and seepage velocity. After 100 days under sea water condition, the coefficients of permeability of A and B samples decreased ten times than initial values. The reduction of permeability coefficient was considered to result from the filling of voids in high-calcium quicklime(CaO).

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Dynamic Damping Characteristics of Grouthed Coal Ash (약액처리된 석탄회의 동적 감쇠특성)

  • Chun, Byung Sik;Chung, Hyoung Sik;Koh, Yong Il;Lee, Hyoung Soo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.11 no.1
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    • pp.145-151
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    • 1991
  • The final purpose of this study is to examine the uses of coal ash, by-product from thermal power plant as a type of filling-embankment materials and the reuses of ash ponds. In this time, to investigate the dynamic properties, we made the test piece specimen with coal ashes, and obtained the damping ratio. In place(ash pond), the damping property by underground wall was investigated before and after soil improvements. The damping ratio of coal ash test piece specimen of 12% cement is the highest and that of 9% cement or chemical grout, that of 6% cement is in order. In same coal ash test piece, the damping ratio increases with decreasing the void ratio. In conclusion, it could be said that the damping ratio increases with the stiffness of materials. In the ash pond, the damping effect is the most when trench is set through the vibration wave propagation course, and when soil is improved the higher stiffness of the improved soil is, the more damping effect appeared. It is justified to obtain not only the dropping of permeability and the strength increase, but also the damping effect fairly by soil improvements.

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Improvement of Analytical Method for Determination of Germanium in Plant by Atomic Absorption Spectrometry (원자흡광분광법에 의한 식물체 중의 게르마늄 분석법 개선)

  • Han, Seong-Soo;Rim, Yo-Sup;Kim, Il-Kwang
    • Analytical Science and Technology
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    • v.10 no.3
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    • pp.179-186
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    • 1997
  • This study was carried out to improve the analytical method for determination of germanium in plants by atomic absorption spectrometry with graphite furnace. For the decomposition of plant samples, the mixed acid of $HNO_3+HClO_4+H_2SO_4$(10 : 4 : 1, v/v) was used. Under this condition, time requirement for the decomposition was 4~5 days and recovery rate was more than 98%. Solution for filling up to constant volume after decomposition was 0.1M acetic acid-sodium acetate. Detection limit for determination of germanium was 0.02 ppm by atomic absorption spectrometry with graphite furnace and argon gas. These results were corresponded with the above-mentioned research projects for improving the determination method of germanium in plants.

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Development of Simulation Program of Two-Stroke Marine Diesel Engines (선박용 2행정 디젤기관의 성능시뮬레이션 프로그램 개발)

  • Choi, Jae-Sung;Jeong, Chan-Ho;Cho, Kwon-Hae;Lee, Jin-Uk;Ha, Tae-Bum;Kim, Houng-Soo
    • Journal of Advanced Marine Engineering and Technology
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    • v.34 no.1
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    • pp.62-68
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    • 2010
  • The requirement of high efficiency and low emission for marine diesel engines are being enforced because of air pollution and climate change on the earth. In connection with these, many new technologies are considered. But they are mainly for new building ship. It is necessary to be concerned about the improvement of engine performance for existing ship. In this paper, the simulation program for performance of marine two-stroke diesel engine was developed to predict the deteriorating performance according to elapsed time for existing ship. The result was compared with the result of the program named TOP-CODE which was used by engine maker and checked to be shown good agreement between them.

Veriation of Pore Structure of High Strength Concrete Including Silica Fume Exposed to High Temperature (고온에 노출된 실리카퓸 혼입 고강도 콘크리트의 공극구조 변화)

  • Song Hun;Soh Yang-Seob
    • Journal of the Korea Concrete Institute
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    • v.16 no.5 s.83
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    • pp.597-604
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    • 2004
  • This work involves quantitatively investigating the correlation between reductions in strength and variations in pore structure under high temperature that can be utilized as estimation for predicting the inner temperature of member damaged by fire. The experimental results were remarkedly affected by micro-filling effect of silica fume and the different water-binder ratios. The increase of the exposure temperature caused the increase of porosity, which resulted from the reason that evaporable water in gel pore or capillary pores as well as chemically bound water was eliminated from hardened cement paste due to the dehydration of C-S-H and $Ca(OH)_2$. Thermal shrinkage of hardened cement paste gives rise to micro-crack, which cause the increase of porosity. Based on the experimental result that the increase of porosity is in charge of exposure temperature, how porosity is distributed can predict temperature-time history and assess the performance of concrete damaged by fire.

Development of a New Simulation Method of Casting Process Based on a Cylindrical Coordinate System (원통좌표를 이용한 주조공정의 수치해석모델 개발)

  • Mok, Jin-Ho;Park, Seong-Joon;Lee, Jin-Ho
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.28 no.4
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    • pp.433-440
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    • 2004
  • Since the numerical analysis was adopted in the mold design, lots of computational methods have been proposed for the simulations of casting processes for the various shaped molds. Today, it is possible to simulate the filling and solidification processes of most casts using the VOF technique. Though the three-dimensional numerical model based on the Cartesian coordinate system can be applied to any shape of cast, it becomes very inefficient when the three-dimensional model is applied to the cast of axi-symmetrical shape since the control volume includes at least 11 of the physical model. In addition, the more meshes should be distributed along the circumferential boundaries of curved shape in the Cartesian coordinate system fur the better results, while such curved circumferential boundary does not need to be considered in the two-dimensional cylindrical coordinate system. This motivates the present study i.e. developing a two-dimensional numerical model for the axi-symmetrically shaped casts. The SIMPLER algorithm, the VOF method, and the equivalent specific heat method have been adopted in the combined algorithm for the flow calculation, the free surface tracking, and the phase change heat transfer, respectively. The numerical model has been applied to the casting process of a pulley, and it was proven that the mesh and time effective calculation was accomplished comparing to the calculation using three-dimensional model.

Efficient Disk Access Method Using Region Storage Structure in Spatial Continuous Query Processing (공간 연속질의 처리에서 영역 기반의 저장 구조를 이용한 효율적인 디스크 접근 방법)

  • Chung, Weon-Il
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.5
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    • pp.2383-2389
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    • 2011
  • Ubiquitous applications require hybrid continuous query processing which processes both on-line data stream and spatial data in the disk. In the hybrid continuous spatial query processing, disk access costs for the high-volume spatial data should be minimized. However, previous indexing methods cannot reduce the disk seek time, because it is difficult that the data are stored in contiguity with others. Also, existing methods for the space-filling curve considering data cluster have the problem which does not cluster available data for queries. Therefore, we propose the region storage structure for efficient data access in hybrid continues spatial query processing. This paper shows that there is an obvious improvement of query processing costs through the contiguous data storing method and the group processing for user queries based on the region storage structure.