• Title/Summary/Keyword: Fgr

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Roles of Src-family kinase isoforms, Lyn, Fyn, Fgr, and c-Src on degranulation in RBL-2H3 mast cells (비만세포의 탈과립에 대한 다양한 Src-family kinase의 역할)

  • Lee, Jun-Ho;Mun, Se-Hwan;Ko, Na-Young;Kim, Jie-Wan;Kim, Do-Kyun;Kim, Joo-Dong;Her, Erk;Choi, Wahn-Soo
    • Journal of Life Science
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    • v.17 no.3 s.83
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    • pp.350-355
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    • 2007
  • The rat RBL-2H3 mast cells contain various Src-family kinases. Previous reports with this cell line indicated that Lyn activation is an important initial signaling for the activation of the cells. However, the role and location of other Src-family kinase isoforms which are expressed in the cells are not clear. In this study, we now show that isoforms of Src-family kinases, Lyn, fyn, Fgr, c-Src, and Yes are differentially expressed and located differently in the cells as indicated by RT-PCR, immunoblotting analysis, and confocal microscopy. Lyn and Fgr were located on plasma membrane but on the other hand c-Src and Yes were located on intracellular organelle. All of Src-family kinases were cloned and overexpressed for investigating the roles of the isoforms. Overexpression of Fyn and Fgr, not Lyn and c-Src, stimulated Ag-induced degranulation in the cells. Our findings strongly suggest for the first time that each of Src-family kinase isoform can regulate differentially $Fc{\varepsilon}RI$-mediated signaling in RBL-2H3 mast cells.

An Experimental Study on Mode Switching from Air-firing to Oxy-firing in Pilot-scale Combustion Systems (미분탄 순산소 연소 운전 모드 전환 과정에 대한 Pilot 규모 설비에서의 실험적 연구)

  • Choi, Chong-Gun;Na, Ik-Hwan;Lee, Jae-Wook;Chae, Tae-Young;Yang, Won;Kim, Young-Ju;Kim, Jong-An;Seo, Sang-Il
    • Journal of the Korean Society of Combustion
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    • v.16 no.3
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    • pp.12-20
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    • 2011
  • Oxy-coal combustion for $CO_2$ capture in coal power plants entails a mode switching from air-firing to oxyfiring. In this study, procedure of the mode switching was investigated and discussed through experiments in pilot scale facilities: (1) a 0.3 $MW_{th}$ furnace with a vertical single burner and a FGR(Flue Gas Recirculation) system (2) a 1 $MW_{th}$ furnace with horizontal 4 burners and a FGR system. Principle of the mode switching was established and performed with control of FD fan, FGR fan, ID fan and oxygen flow rates. We have found that equivalence ratio in the oxy-firing mode should be increased more than that in the air-firing to achieve stable mode switching. Control of FD, ID and FGR fans should be performed carefully in the mode switching, in the sense of complete combustion and flame attachment. Moisture contents in the ash and the flue gas recycled to the primary oxidizer stream should be removed to prevent condensation, corrosion and duct clogging.

A Study on an Transmission Right Issuance Quantity Assessment Method by using Power Transfer Distribution Factor(PTDF) under FlowGate Right(FGR) (FlowGate Right(FGR) 도입 시 Power Transfer Distribution Factor(PTDF)를 이용한 송전권 계약용량 산정 방법 연구)

  • Baeck, Woong-Ki;Bang, Young-Sun;Chun, Yeong-Han;Kim, Jung-Hoon;Kwak, No-Hong;Lee, Baek-Seok
    • Proceedings of the KIEE Conference
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    • 2005.07a
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    • pp.861-863
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    • 2005
  • LMP based congestion management method is suggested as an effective tool, because network congestion can be handled by energy price. It is now being widely used in the North American Electricity Markets. Among them, FGR(Flow-gate rights) is considered to be appropriate for our system, as power flow through the congested line is unidirectional and congestion occurs in the known place. In the CBP market, hedging through transmission right is not necessary even though location pricing system is adopted, because there are no risks in the energy price. Rut, transmission rights should be adopted in the advanced market. Key issue when implementing FGR is how to decide transmission right issuance quantify. This paper deals with a method to decide transmission right issuance quantity by using power. Transfer Distribution Factor(PTDF).

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Experiment on Low $NO_x$ Combustion Characteristics by Flue Gas Dilution In Air and Fuel Sides (공기 및 연료에 대한 배기가스 희석 방법에 의한 저 $NO_x$ 연소특성에 관한 실험)

  • Cho, Eun-Seong;Chung, Suk-Ho
    • Proceedings of the KSME Conference
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    • 2004.04a
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    • pp.1499-1504
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    • 2004
  • Flue gas recirculation (FGR) is a method used to control oxides of nitrogen ($NO_x$) in combustion system. The recirculated flue gases resulted in slow reaction and low flame temperatures, which in turn resulted in decreased thermal NO production. Recently, it has been demonstrated that introducing the recirculated flue gas in the fuel stream, that is, the fuel induced recirculation (FIR), resulted in a much greater reduction in $NO_x$ per unit mass of recirculated gas, as compared to introducing the flue gases in air. In the present study, the effect on $NO_x$ reduction in turbulent swirl flame in laboratory scale using FGR/FIR methods through the dilution using $N_2$ and $CO_2$. Results. show the $CO_2$ dilution is more effective $NO_x$ reduction methods because of large temperature drop due to the larger specific heat $CO_2$ compared to $N_2$. FIR is more effective to reduce $NO_x$ emission than FGR when the same recirculation ratio of dilution gas.

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Preliminary Analysis of In-reactor Behavior of Three MOX Fuel Rods in the Maiden Reactor

  • Koo, Yang-Hyun;Lee, Byung-Ho;Sohn, Dong-Seong
    • Proceedings of the Korean Nuclear Society Conference
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    • 1999.10a
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    • pp.248.1-248
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    • 1999
  • Preliminary analysis of in-reactor thermal performance of three MOX fuel rods, which are going to be irradiated in the Halden reactor beginning in the first Quarter of the year 2000 under the framework of the OECD Halden Reactor Programme, have been conducted by using the computer code COSMOS to ensure their safe operation. Parametric studies have been carried out to investigate the effect of uncertainties on in-reactor behavior by considering the four kinds of uncertainties; thermal conductivity, linear power, manufacturing parameters, and model constants. The analysis shows that, in the case of annular MOX -1 fuel, calculation results for thermal performance vary widely depending on the selection of model constants for fission gas release (FGR). On the contrary, the thermal performance of solid MOX - 3 fuel does not depend on the choice of FGR constants to a large extent as MOX-I, because the fuel temperature is very high in the MOX-3 irrespective of the choice of FGR constants and hence the capacity of grain boundaries to retain gas atoms is not large enough to accommodate the number of gas atoms reaching the grain boundaries. It is planned that when the data on microstructure and thermal conductivity for each type of MOX fuel are available, new analysis will be made using these information. In addition, FGR model constants will be derived from the measured fuel centerline temperature, rod internal pressure and other related data.

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Investigation on Flame Characteristics′ Variation by Flue Gas Recirculation and Fuel Injection Recirculation (산화제류 및 연료류 희석에 의한 화염특성변화에 대한 연구)

  • Han, Ji-Woong;Kum, Sung-Min;Lee, Chang-Eon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.28 no.12
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    • pp.1625-1631
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    • 2004
  • Investigation on Flue Gas Recirculation(FGR) flame and Fuel Injection Recirculation(FIR) flame was performed with numerical method. Quantitative Reaction Path Diagram(QRPD) is utilized to compare the different chemistry effects between FGR flame and FIR flame. In order to compare flamelets in various oxygen-enrichment conditions reasonably, the adiabatic flame temperature and Damkohler number were held fixed by modulating the amount of diluents to fuel and oxidizer stream and by varying global strain rate of flame respectively. Basic flame structures were compared and characteristics of CH$_4$ decomposition and NO formation were analyzed based on QRPD analysis between FGR flame and FIR flame.

An Experimental study on swirl flow and combustion characteristics of 3 staged low NOx burner applied with FGR and FIR (FGR 및 FIR을 적용한 3단 저 NOx 버너의 Swirl유동 및 연소특성에 관한 실험적 연구)

  • Shin, Myung-Chul;Kim, Se-Won;Cha, Hak-Ju
    • 한국연소학회:학술대회논문집
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    • 2002.11a
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    • pp.105-112
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    • 2002
  • The objective of this research is to determine generally applicable design principles for the development of internally staged combustion devices. Utilizing a triple annulus combustor, air staged commercial propane flame configuration are studied. For this triple air staged combustor, the angular momentum weighted by it's swirl number and air distribution ratio was observed to be the critical criteria. An internal recirculation zone which develops on the centerline of the flame immediately downstream of the burner entraps the fuel into a fuel rich eddy. Then sufficient heat must he transferred from the flame via radiation to the chamber heat transfer surfaces, such that when the second air is introduced, peak flame temperatures are suppressed. It is experimentally found out that the total NOx emission level in this type of burner is lower than 0.75g/kg.

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Oxy-Fuel and Flue Gas Recirculation Combustion Technology: A Review (순산소 및 배가스 재순환 연소 기술)

  • Kim, Hyeon-Jun;Choi, Won-Young;Bae, Soo-Ho;Shin, Hyun-Dong
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.32 no.10
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    • pp.729-753
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    • 2008
  • Oxy-fuel combustion is a reliable way for the reduction of pollutants, the higher combustion efficiency and the separation of carbon dioxide. The review of recent research trends and the prospects of oxy-fuel combustion were presented. The difference in characteristics among oxy-fuel combustion, conventional air combustion, oxy-fuel combustion with flue gas recirculation (FGR) technique was investigated. Recent experiments of oxy-fuel combustion with/without FGR were surveyed in various ways which are optimized burner design, flame characteristics, the soot emission, the radiation effect, the NOx reduction and the corrosion of combustor. Numerical simulation is more important in oxy-fuel combustion because flame temperature is so high that conventional measurement devices have a restricted application. Equilibrium and non-equilibrium chemical reaction mechanisms for oxy-fuel combustion were investigated. Combustion models suitable for the numerical simulation of non-premixed oxy-fuel flame were surveyed.

Numerical Study on NO Emission with Flue Gas Dilution in Air and Fuel Sides

  • Cho Eun-Seong;Chung Suk Ho
    • Journal of Mechanical Science and Technology
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    • v.19 no.6
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    • pp.1358-1365
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    • 2005
  • Flue gas recirculation (FGR) is widely adopted to control NO emission in combustion systems. Recirculated flue gas decreases flame temperature and reaction rate, resulting in the decrease in thermal NO production. Recently, it has been demonstrated that the recirculated flue gas in fuel stream, that is, the fuel induced recirculation (FIR), could enhance much improved reduction in NO per unit mass of recirculated gas, as compared to conventional FGR in air. In the present study, the effect of dilution methods in air and fuel sides on NO reduction has been investigated numerically by using $N_2$ and $CO_2$ as diluent gases to simulate flue gases. Counterflow diffusion flames were studied in conjunction with the laminar flamelet model of turbulent flames. Results showed that $CO_2$ dilution was more effective in NO reduction because of large temperature drop due to the larger specific heat of $CO_2$ compared to $N_2$. Fuel dilution was more effective in reducing NO emission than air dilution when the same recirculation ratio of dilution gas was used by the increase in the nozzle exit velocity, thereby the stretch rate, with dilution gas added to fuel side.

Comparison of Electrical Properties of β-Gallium Oxide (β-Ga2O3) Power SBDs with Guard Ring Structures (Guard Ring 구조에 따른 β-산화갈륨(β-Ga2O3) 전력 SBDs의 전기적 특성 비교)

  • Hoon-Ki Lee;Kyujun Cho;Woojin Chang;Jae-Kyoung Mun
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.37 no.2
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    • pp.208-214
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    • 2024
  • This reports the electrical properties of single-crystal β-gallium oxide (β-Ga2O3) vertical Schottky barrier diodes (SBDs) with a different guard ring structure. The vertical Schottky barrier diodes (V-SBDs) were fabricated with two types guard ring structures, one is with metal deposited on the Al2O3 passivation layer (film guard ring: FGR) and the other is with vias formed in the Al2O3 passivation layer to allow the metal to contact the Ga2O3 surface (metal guard ring: MGR). The forward current values of FGR and MGR V-SBD are 955 mA and 666 mA at 9 V, respectively, and the specific on-resistance (Ron,sp) is 5.9 mΩ·cm2 and 29 mΩ·cm2. The series resistance (Rs) in the nonlinear section extracted using Cheung's formula was 6 Ω, 4.8 Ω for FGR V-SBD, 10.7 Ω, 6.7 Ω for MGR V-SBD, respectively, and the breakdown voltage was 528 V for FGR V-SBD and 358 V for MGR V-SBD. Degradation of electrical characteristics of the MGR V-SBD can be attributed to the increased reverse leakage current caused by the guard ring structure, and it is expected that the electrical performance can be improved by preventing premature leakage current when an appropriate reverse voltage is applied to the guard ring area. On the other hand, FGR V-SBD shows overall better electrical properties than MGR V-SBD because Al2O3 was widely deposited on the Ga2O3 surface, which prevent leakage current on the Ga2O3 surface.