• Pediatric Infection and Vaccine
• /
• 제4권1호
• /
• pp.97-105
• /
• 1997

목 적 : 무균성 뇌막염은 소아에서 많이 발병하는 질환으로 여름과 가을에 많이 호발하며 원인은 주로 장바이러스(enterovirus)로 알려져 있다. 감염된 환아들은 단기간에 증상이 좋 아지며 대부분 합병증 없이 회복된다. 이에 저자들은 1996년 5왈말부터 8월까지 마산지역을 중심으로 무균성 뇌막염이 유행하였던 바 뇌막염 환자 및 뇌막염 증상은 보이지 않으나 고열과 발진을 주소로 내원한 환아에서 원인 바이러스를 규명하고 임상 증상과의 관계를 추구 하고자 본 연구를 시행하였다. 방 법 : 1996년 5월부터 8월까지 마산파티마 병원에 무균성 뇌막염으로 진단된 환아 및 고열이 나면서 몸에 특징적인 발진이 생겨 바이러스 감염이라고 생각되었던 환아 155명중 57명에서 검체를 채취하여 (뇌척수액22례, 대변57례) 바이러스 배양과 장바이러스 (enterovirus) RNA의 검출을 시행하였다. 뇌척수액은 요추천자를 하여 무균 튜브에 채취하였고 대변은 면봉법으로 채취하여 무균 튜브에 넣어서 검사 전까지 $-30^{\circ}C$ 냉동고에 보관하여 검사실까지 운반시는 밀봉된 용기에 드라이아이스를 넣어 이송하였다. 채취된 뇌척수액과 대변에서 바이러스 분리를 시행하고 면역형광법을 이용하여 바이러스를 동정하였다. 바이러스 배양에 사용한 세포주들은 human embryonal rhabdomyosarcoma(RD), African green monkey kidney(BS-C-1), human lung diploid(MRC-5), human cervix epidermoid carcinoma(HeLa)세포주였고 뇌척수액에서의 장바이러스 RNA는 reverse transcription-polymerase chain reaction(RT-PCR)을 이용하여 확인하였다. 결 과 : 1) 바이러스 감염으로 인하여 입원하였던 환아는 155명이었으며 남녀의 비는 1.94:1로 남아가 많았고 연령분포는 생후 15일부터 15세까지 다양한 연령층의 분포를 보였으나 주로 5세미만에서 발생하였으며(74.8%) 시기상으로는 1996년 5월부터 1996년 8월까지 환자가 발생 하였다. 2) 임상 증상은 전례에서 고열이 동반되었으며 그 외에 두통, 구토, 복통, 설사, 발진이 주된 임상 증상이었으며 발진은 4세 미만에서, 특히 18개월 이하에서 많이 관찰되었다 (p<0.001). 3) 뇌척수액을 이용한 RT-PCR 결과는 22례 중 10례에서 양성의 결과가 나왔고 그중 3례에서 echovirus type 9이 분리되었다. 4) 대변검체가 의뢰된 환자 54례중 41례에서 바이러스가 분리되었으며 분리된 바이러스는 모두 echovirus type 9 이었다. 결 론 : 1996년도 상반기에 경상남도 중부 지방에서 유행한 무균성 뇌막염의 원인 바이러스와 같은 시기에 유행한 고열과 발진의 원인 바이러스는 동일한 바이러스로서 모두 echovirus type 9 이었다.

• Journal of Forest and Environmental Science
• /
• 제29권4호
• /
• pp.257-274
• /
• 2013

Ecological and ethnomedicinal survey of plants was conducted in one hundred and twenty homesteads in Mbala, Amuda, Umuaku, and Nneato communities of Nneochi Local Governement Area, Abia State-Nigeria. A total of ninety-one medicinal plant species belonging to seventy-eight genera and forty-eight families, used in the treatment of malaria, yellow fever, fibroid, hepatitis, convulsion, hypertension, diabetes, insomnia, ulcer, rashes, low sperm count, snake bite, among others, were documented. Plant remedies were prepared mostly as infusions or decoctions from different plant parts with mainly water, and palm wine/gin sometimes. The highest number of medicinal plant species (73) was recorded in Mbala, followed by Amuda (71), Umuaku (68) and Nneato (61). Medicinal plant species diversity was highest in Amuda (Simpson 1-D=0.9621;H=3.663), followed by Umuaku (Simpson 1-D=0.9481; H=3.471), Mbala (Simpson 1-D=0.9345; H=3.341), and Nneato (Simpson 1-D=0.9307; H=3.277), respectively. Similarity in medicinal plant species was highest between Umuaku and Nneato (76.71%), followed by Amuda and Umuaku (75.95%), Mbala and Amuda (71.43%), while Mbala and Nneato had the lowest similarity (59.52%). The results of the study showed that traditional medicine is pivotal in the treatment of ailments in the study area, and that the indigenous people of Nneochi have recognized the need to conserve medicinal plants of importance ex situ within homesteads due to threats from unsustainable exploitation and deforestation.

• Journal of Chest Surgery
• /
• 제19권4호
• /
• pp.744-749
• /
• 1986

Even in the hands of the expert endoscopists, an occasional instrumental perforation of the esophagus occurs. But instrumental perforation of the esophagus should not be difficult to diagnose if the possibility is borne in mind. Occasionally patient with esophageal perforations show little reaction at first, but usually they develop systemic manifestation if surgical management is delayed. Early surgical drainage of esophageal perforation is very important & effective therapeutic method. The delayed surgical treatment of esophageal perforation would have increased the morbidity & mortality by allowing mediastinitis & empyema thoracis. We have experienced 6 cases of delayed surgical management of instrumental perforation of esophagus from May 1974 to April 1986 in the department of thoracic and cardiovascular surgery, Yonsei University, college of the medicine. The ages ranged from 4 years to 57 years. The underlying esophageal diseases consisted of esophageal stricture in 3 cases, foreign bodies in the esophagus in 2 cases and esophageal ca. in one case. Most clinical manifestations on admission were high fever, chest discomfort, chest pain, dysphagia and subcutaneous emphysema. Most complications due to esophageal rupture were acute mediastinitis with or without empyema thoracis. Failure to diagnose promptly and failure to promptly institute adequate treatment undoubtedly were largely responsible for this patients death. All 6 patients had been taken delayed surgical drainage more than 24 hours following esophageal perforation. One patient had been in the open drainage state for long time and the another patient has been in the tracheostomy with postintubation vocal cord ulceration. The third patient died due to respiratory failure and sepsis due to fulminant mediastinitis & empyema thoracis. Even if the patients with esophageal perforation have been taken delayed surgical management, the patients should be survived with aggressive & effective surgical drainage with intensive post-operative care.

• 한국산학기술학회논문지
• /
• 제12권9호
• /
• pp.4075-4082
• /
• 2011

항공기 승무원은 최초 반응자로 비행기내 환자 발생 시 적절하고 신속하게 응급처치를 시행하여야 한다. 승무원의 기본응급처치 의식조사 결과, 출혈 관리, 소아 고열, 경련, 심근경색, 기도유지, 부분기도폐쇄 등에 대한 대처방법은 80.5%~97.8%로 올바르게 의식하고 있었지만 의식 없는 기도폐쇄, 호흡확인 방법, 영아자동제세동기 사용 등에 대한 대처방법은 3.2%~20.0%로 비교적 낮게 나타났다. 따라서, 본 연구결과를 바탕으로 기내에서 발생되는 환자 중 발생빈도가 높은 유형, 해결하기 어려운 유형, 생명을 위협할 수 있는 유형 등에 대한 응급처치 매뉴얼이 마련되어야 된다.

• 아태비즈니스연구
• /
• 제12권1호
• /
• pp.71-86
• /
• 2021

Purpose - This study examines the awareness regarding the symptoms of COVID-19 exposures and safety distances strategies whether they were useful to resile the businesses a mid of the pandemic. Besides exploring the awareness and safety distances, the effectiveness of offering free use of protective equipment (mask, hand sanitizer, frequent hand washing, etc.) to the customers for visiting the business centers was also examined. Design/methodology/approach - This study collected 264 survey data in Bangladesh which is one of the most densely populated country and very vulnerable for COVID-19 due to its socio-economic condition. The multiple regression analysis is used to analyze the data. Findings - The findings of the study indicate that the awareness about the symptoms of virus exposures (cough, fever, diarrhea, and weakness) has significant affirmative effects to enhance the public movement for business purposes with the lower possibility to be affected by the virus. The study also indicates that safety distances and protective equipment can mediate the significant positive relationship between the awareness of the disease and the businesses' resilient capacity. Research implications or Originality - COVID-19, as an apprehensive health issue in the current world, has sharpened the uncertainty of the businesses. One essential technique as lockdown, has been followed by almost every country to protect the transmission of the virus even though the scholars criticized it due to the substantial adverse effects on the country's economy. Under this circumstances, this study provides implications to the relevant businesses by assessing the nexus between the safety distances and the proper uses of protective equipment with the business resilient.

• 보건행정학회지
• /
• 제33권1호
• /
• pp.29-39
• /
• 2023

Background: Breaking the chain of disease transmission from overseas is necessary to control new infectious diseases such as coronavirus disease 2019 effectively. In this study, we developed a mobile app called Self-Symptom Checker (SSC) to monitor the health of inbound travelers. Methods: SSC was developed for general users and administrators. The functions of SSC include non-repudiation using QR (quick response) codes, monitoring fever and respiratory symptoms, and requiring persons showing symptoms to undergo polymerase chain reaction tests at nearby screening stations following a review of reported symptoms by the Korea Disease Control and Prevention Agency, as well as making phone calls, via artificial intelligence or public health personnel, to individuals who have not entered symptoms to provide the necessary information. Results: From February 12 to March 27, 2020, 165,000 people who were subjected to the special entry procedure installed SSC. The expected number of public health officers and related resources needed per day would be 800 if only the phone was used to perform symptom monitoring during the above period. Conclusion: By applying SSC, more effective symptom monitoring was possible. The daily average number of health officers decreased to 100, or 13% of the initial estimate. SSC reduces the work burden on public healthcare personnel. SSC is an electronic solution conceived in response to health questionnaires completed by inbound travelers specified in the World Health Organization International Health Regulations as a requirement in the event of a pandemic.

• Child Health Nursing Research
• /
• 제20권3호
• /
• pp.149-158
• /
• 2014

목적 열성경련 아동 보호자를 대상으로 열성경련에 대한 지식, 염려 및 관리 실태를 조사하고, 대상자 특성에 따른 지식, 염려 및 관리 점수의 차이를 파악하고, 이들 변수간의 관련성을 파악하기 위한 목적으로 실시한 조사연구이다. 방법 본 연구 대상자는 아동의 열성경련을 경험한 일 지역의 아동 보호자 133명이었으며, 자료수집은 구조화된 설문지를 이용하여 자기기입식 또는 면담을 통해 이루어졌다. 수집된 자료는 기술통계, t-검정, 일원분산분석, 피어슨 상관분석을 통해 분석하였다. 결과 열성경련에 대한 아동 보호자들의 지식수준은 낮았으며(정답률 48.5%), 잘못된 편견으로 인한 열성경련에 대한 염려수준은 높았고(3.44점), 열성경련의 발생 시 적절한 관리가 이루어지지 않고 있고 있었다(정답률 64.4%). 대상자의 특성에 따른 열성경련에 대한 지식과 염려 점수의 차이를 살펴본 결과, 아동과의 관계가 어머니인 경우보다 친인척이나 기타였던 경우 그리고 대상자가 기혼자였던 경우보다 이혼, 사별 및 기타였던 경우가 통계적으로 유의하게 지식점수는 낮았으며 염려점수는 높았다. 또한 이전에 열성경련을 경험하지 않았던 아동 보호자가 통계적으로 유의하게 지식점수가 낮았다. 또한 지식 점수와 염려 점수는 통계적으로 유의한 음의 상관관계가 있었고, 지식 점수와 대처 점수는 통계적으로 유의한 양의 상관관계가 있었다. 결론 따라서 아동 보호자들을 대상으로 아동의 열성경련에 대한 지식 및 관리 수준을 높이고, 열성경련에 대한 잘못된 편견으로 인한 불필요한 염려 수준을 낮추어 주기 위한 교육 프로그램의 개발, 적용 및 평가가 요구된다.

• Clinical and Experimental Pediatrics
• /
• 제48권3호
• /
• pp.235-250
• /
• 2005

Acute diarrhea is one of the most common diseases that are seen in pediatric patients. In the management of acute diarrhea, several differential diagnostic criteria should be considered based on clinical and/or laboratory findings. These criteria include : (1) normal variant stool versus diarrhea (2) infectious versus non-infectious condition and (3) bacterial versus non-bacterial etiology. The use of antibiotics should be considered to manage diarrhea caused by bacteria accompanying fever and bloody diarrhea in the following cases : (1) patients with serious clinical course, (2) under three months, (3) immunocompromised patients, (4) patients with nutritional deficiency and (5) patients presenting with moderate-to-severe dehydration. In patients presenting with the symptoms suspected to be bacterial origin, whose clinical course is not serious, antibiotic therapy is not necessary. These patients are easily manageable at OPD level. Moreover, except for some cases in which the use of antibiotics is inevitable, pediatric diarrhea can be managed by providing the suitable foods alone with no necessity of other specific drugs. Accordingly, it is crucial not so much to depend on the drugs as to provide appropriate foods including oral rehydration solution(ORS) with no further episodes of diarrhea. Special attention should be paid to the fact that younger pediatric patients will undergo nutritional deficiency unless acute diarrhea is properly managed.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제12권1호
• /
• pp.70-74
• /
• 2009

저자들은 급성 복통을 주소로 내원한 10세 남아에서 복부 초음파와 복부 전산화단층촬영을 통하여 대망 경색을 진단하였으며 항생제 및 진통제 등의 보존적인 치료로 증상의 완화를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제17권4호
• /
• pp.263-265
• /
• 2014

Epiploic appendagitis is an inflammation of the epiploic appendage in which the small sacs projecting from the serosal layer of the colon are positioned longitudinally from the caecum to the rectosigmoid area. Epiploic appendagitis is rare and self-limiting; however, it can cause sudden abdominal pain in children. Epiploic appendagitis does not typically accompany other gastrointestinal diseases. Here, we report on a healthy eight-year-old girl who presented with abdominal pain, fever, vomiting, and diarrhea. Based on these symptoms, she was diagnosed with acute gastroenteritis, but epiploic appendagitis in the ascending colon was revealed in contrast computed tomography (CT). The patient was treated successfully with conservative management. CT is beneficial in diagnosis and further assessment of epiploic appendagitis. Pediatricians need to be aware of this self-limiting disease and consider it as a possible alternate diagnosis in cases of acute abdominal pain.