• Title/Summary/Keyword: Feasible region

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A Study on the Alternative Approach to Sustainable Tourism Development in Cameroon (지속가능한 관광개발 전략에 관한 연구: 카메룬 관광개발을 중심으로)

  • Lee, Seung-Koo;Sakwe, Nanje Divine
    • Korean Business Review
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    • v.22 no.2
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    • pp.35-59
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    • 2009
  • The drive for sustainable economic growth for the sub Saharan African region continues to occupy a central place in the debate of how to move the region forward. For decades, governments, policy makers, Non Governmental Organizations and world bodies including the World Bank, IMF, ADB, USIAD and the European Union have engaged policies aimed at bringing solutions to the horrendous poverty crisis to nations of this region. Despite these noble actions and intents, poverty and underdevelopment has prevailed in countries of the region such as Cameroon. Cameroon is mainly an agricultural economy with its products facing declining prices and competition from synthetic substitutes resulting to deficits of balance of trades. This has resulted to borrowing and debt. At the same time, it is a country blessed with an abundance of tourist resources. From the literature review, tourism potency to economic growth is overwhelming. This research was motivated by the quest to find answers to questions such as; why development policies during the last two decades not succeeded in achieving Economic growth in countries of this region particularly Cameroon and why the country/ region still beleaguered by poverty and debt despite haven implemented various economic development plans. In recent years, the role of tourism has become increasingly recognized in its role of economic growth and poverty alleviation. This study attempts to unveil tourism's contribution to economic growth and to push for Tourism development as an al ternative economic growth alternative to Cameroon. Previous economic policies have ignored to tie economic growth within the country's socio-economic, geo-political and environmental circumstances. Findings from this work suggest that any sound economic policy can not afford to ignore the country's stock of both human and fiscal capital. Findings presented herewith validate Tourism as a feasible indigenous economic growth alternative that helps bringing employment, capital investment and protect the environmental ruin.

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Clinical Application of Endoscopic Inguinal Lymph Node Resection after Lipolysis and Liposuction for Vulvar Cancer

  • Wu, Qiang;Zhao, Yi-Bing;Sun, Zhi-Hua;Ni, Jing;Wu, Yu-Zhong;Shao, Heng-Hua;Qu, Jun-Wei;Huang, Xin-En
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7121-7126
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    • 2013
  • Aim: To examine lymph nodes obtained after lipolysis and liposuction of subcutaneous fat of the inguinal region of female vulvar cancer patients to explore the feasibility of clinical application. Methods: The field of operation was on the basis of the range of the conventional resection of inguinal lymph nodes. We injected lipolysis liquid fanwise, started liposuction after 15-20 minutes; then the subcutaneous fatty tissue was sucked out clearly by suction tube. We selected the first puncture holes located on 2-3 cm part below anterior superior spine, the others respectively being located 3cm and 6cm below the first for puncturing into the skin, imbedding a trocar to intorduce $CO_2$ gas and the specular body, and excise the lymph nodes by ultrasonic scalpel. The surgical field chamber was set with negative pressure drainage and was pressured with a soft saline bag after surgery. Results: A lacuna emerged from subcutaneous of the inguinal region after lipolysis and liposuction, with a wide fascia easily exposed at the bottom where lymph nodes could be readily excised. The number of lymph nodes of ten patients excised within the inguinal region on each side was 4-18. The excised average number of lymph nodes was 11 when we had mature technology. Conclusion: Most of adipose tissue was removed after lipolysis and liposuction of subcutaneous tissue of inguinal region, so that the included lymph nodes were exposed and easy to excise by endoscope. This surgery avoided the large incision of regular surgery of inguinal region, the results indicating that this approach is feasible and safe for used as an alternative technology.

Magnetic Position Sensing System for Autonomous Vehicle and Robot Guidance (자율주행차량과 로봇의 안내를 위한 자계위치인식시스템)

  • Jung, Young-Yoon;Kim, Geun-Mo;Ryoo, Young-Jae
    • Journal of the Korean Institute of Intelligent Systems
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    • v.17 no.2
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    • pp.214-219
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    • 2007
  • In this paper, a new magnetic position sensing mettled for autonomous vehicle and robot guidance is presented. In autonomous vehicle and robot control, position sensing is an important task for the identification of their locations, such as the current position within a trajectory. The magnet based autonomous vehicle and robot was identified position via magnetic materials. In the magnetic sensing system, the Earth field is one of the largest disturbance. To removal of the Earth field, this paper proposes 1-dimensional magnetic field sensors array and develops precise petition sensing system using linear operating region of the magnetic field sensor. This proposal is verified a feasible magnetic position sensing system for autonomous vehicle and robot guidance by the experimental results.

Performance Analysis of random access channels in multi-service multi-user OFDMA systems (다중 서비스 다중 사용자 OFDMA 시스템에서의 임의접근 채널 성능 분석)

  • Koo, In-Soo;Pham, Thi Hong Chau
    • Journal of Internet Computing and Services
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    • v.9 no.5
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    • pp.141-151
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    • 2008
  • In the paper, we analyze the performance of random access channels in multi-service multi-user OFDMA systems. The resource of the random access channels in OFDMA systems are available sub-channels and PN-codes. For given available sub-channels and PN-codes,' we analyze the performance of the random access channels of OFDMA systems in terms of the access success probability, the blocking probability, the access delay and the throughput per each service class. Further, we find the feasible region of the access probability of each service class in which the allowable minimum access success probability, the allowable maximum blocking probability and the allowable maximum access delay are satisfied. The results also can be used to find proper region of the access probabilities of each service class for differentiated quality of service(QoS)s, and for the system operations in multi-service multi-user OFDMA systems.

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Intracranial Hemangiopericytomas : A Retrospective Study of 15 Patients with a Special Review of Recurrence

  • Noh, Sung Hyun;Lim, Jae Joon;Cho, Kyung Gi
    • Journal of Korean Neurosurgical Society
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    • v.58 no.3
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    • pp.211-216
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    • 2015
  • Objectives : Although surgical resection is used to treat meningeal hemangiopericytoma (MHPC), there is a high risk of subsequent recurrence. This study investigated factors associated with treatment outcomes and recurrence in patients who had undergone surgical resection of intracranial MHPC. Methods : Fifteen patients underwent surgical treatments performed by one senior neurosurgeon between 1997 and 2013. Clinical data, radiologic images, surgical outcomes, recurrence, and other relevant characteristics were reviewed and analyzed. Results : Fifteen patients were included in the analysis, 12 (80%) of whom had tumors in the supratentorial region, and 3 (20%) of whom had tumors in the infratentorial region. Complete resection was achieved in all 15 patients, and 3 (20%) patients were administered radiosurgery and conventional radiotherapy after surgery as adjuvant radiotherapy. Three patients developed recurrence, 2 of whom had not received adjuvant radiotherapy. In 1 of the patients who had not received adjuvant radiotherapy, recurrence developed at the original tumor site, 81 months after surgery. The other 2 recurrences occurred at other sites, 78 and 41 months after surgery. The 5- and 10-year overall survival rates were 88.3%, while the 5- and 10-year recurrence-free survival rates were 83% and 52%, respectively. Additionally the mean Ki-67 index differed significantly between patients who did and did not develop recurrence (43% vs. 14%; p=0.001). Conclusion : Because of the high risk of MHPC recurrence, MHPC tumors should be completely resected, whenever feasible. However, even when complete resection is achieved, adjuvant radiotherapy might be necessary to prevent recurrence.

Korean Suicide Risk Screening Tool and its Validity (한국형 자살위험 스크리닝 도구와 타당성)

  • Kim, Jieun;Kang, Eunjeong;Jeong, Jin-Wook;Paik, Jong-Woo
    • The Journal of the Korea Contents Association
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    • v.13 no.3
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    • pp.240-250
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    • 2013
  • The early detection of suicidal ideation is essential for the prevention of suicide. This study aimed to develop a brief screening tool that can be easily administered in medical settings. The Suicide Risk Screening Tool was designed for use by physicians to provide a screening process that would be reliable, standardized, quick and feasible to implement. A 2-item screening tool was derived from the Screening for Depression and Thoughts of Suicide in the Norton Sound region of Alaska, USA. The scale was modified to reflect the current situation in Korea including the elimination of the personal identification number, and was labeled the Korean Suicide Risk Screening Tool. Its reliability and applicability for medical setting were examined by explanatory study of 7 clinicians. Its validity was examined among a further 325 patients of four different medical institutions, using the results of interviewer-administered survey included demographic, clinical characteristics, and present mental status as the external criterion. A brief 2-item suicide risk screening tool can be used by mental and non-mental health clinicians to accurately detect suicidality in patients.

A Study on Orbit Stability and Control Method for Displaced Non-Keplerian Orbits by Using Pitch Angle Variation (변위 비케플러 궤도의 안정성 분석 및 피치각 변화를 이용한 제어기법 연구)

  • Kim, Mingyu;Lee, Jeongpyo;Kim, Jeongrae
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.42 no.10
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    • pp.823-832
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    • 2014
  • Displaced non-Keplerian orbit, center of mass is displaced from orbit plane, enables special spacecraft missions. It requires continuous thrust to maintain the orbit, and solar sail is useful for this purpose. Equations for feasible region and stability analysis are derived for non-Keplerian orbit for general continuous thrust. Differences for solar sail spacecraft are discussed. Non-keplerian orbits are classified into four types. Location-specific required accelerations for orbit maintenance are calculated. Orbit stabilities of each orbit type are analyzed and verified by numerical simulations. In order to control non-Keplerian orbit in unstable region, a control algorithm using the real-time LQR control is developed and evaluated by numerical simulations.

Feasibility of Intra-Operative BNCT Using Accelerator-Based Near-Threshold $^7Li(p,n)^7$Be Direct Neutrons

  • Tanaka, Kenichi;Kobayashi, Tooru;Nakagawa, Yoshinobu;Sakurai, Yoshinori;Ishikawa, Masayori;Hoshi, Masaharu
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.157-160
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    • 2002
  • The dosage of intra-operative BNCT using near-threshold $^{7}$ Li(p,n)$^{7}$ Be direct neutrons was evaluated with the calculation method validated with the phantom experiment. The production of both neutrons by near-threshold $^{7}$ Li(p,n)$^{7}$ Be and gamma rays by $^{7}$ Li(p,p'gamma)$^{7}$ Li in a Li target was calculated using Lee's method and their transport in the phantom was calculated with MCNP-4B. As a result, the region satisfying the requirements of the protocol in intra-operative BNCT for brain tumors in Japan was acknowledged to be comparable to present BNCT, for the proton energy of 1.900 MeV for example. A boron-dose enhancer (BDE) introduced in this study to increase $^{10}$ (n,$\alpha$)$^{7}$ Li dose in a living body was effective. The void used to increase doses in deep regions was also valid with the BDE. It was found that intra-operative BNCT using near-threshold $^{7}$ Li(p,n)$^{7}$ Be direct neutrons is feasible.

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Dynamic Human Pose Tracking using Motion-based Search (모션 기반의 검색을 사용한 동적인 사람 자세 추적)

  • Jung, Do-Joon;Yoon, Jeong-Oh
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.7
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    • pp.2579-2585
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    • 2010
  • This paper proposes a dynamic human pose tracking method using motion-based search strategy from an image sequence obtained from a monocular camera. The proposed method compares the image features between 3D human model projections and real input images. The method repeats the process until predefined criteria and then estimates 3D human pose that generates the best match. When searching for the best matching configuration with respect to the input image, the search region is determined from the estimated 2D image motion and then search is performed randomly for the body configuration conducted within that search region. As the 2D image motion is highly constrained, this significantly reduces the dimensionality of the feasible space. This strategy have two advantages: the motion estimation leads to an efficient allocation of the search space, and the pose estimation method is adaptive to various kinds of motion.

Paired analysis of tumor mutation burden calculated by targeted deep sequencing panel and whole exome sequencing in non-small cell lung cancer

  • Park, Sehhoon;Lee, Chung;Ku, Bo Mi;Kim, Minjae;Park, Woong-Yang;Kim, Nayoung K.D.;Ahn, Myung-Ju
    • BMB Reports
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    • v.54 no.7
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    • pp.386-391
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    • 2021
  • Owing to rapid advancements in NGS (next generation sequencing), genomic alteration is now considered an essential predictive biomarkers that impact the treatment decision in many cases of cancer. Among the various predictive biomarkers, tumor mutation burden (TMB) was identified by NGS and was considered to be useful in predicting a clinical response in cancer cases treated by immunotherapy. In this study, we directly compared the lab-developed-test (LDT) results by target sequencing panel, K-MASTER panel v3.0 and whole-exome sequencing (WES) to evaluate the concordance of TMB. As an initial step, the reference materials (n = 3) with known TMB status were used as an exploratory test. To validate and evaluate TMB, we used one hundred samples that were acquired from surgically resected tissues of non-small cell lung cancer (NSCLC) patients. The TMB of each sample was tested by using both LDT and WES methods, which extracted the DNA from samples at the same time. In addition, we evaluated the impact of capture region, which might lead to different values of TMB; the evaluation of capture region was based on the size of NGS and target sequencing panels. In this pilot study, TMB was evaluated by LDT and WES by using duplicated reference samples; the results of TMB showed high concordance rate (R2 = 0.887). This was also reflected in clinical samples (n = 100), which showed R2 of 0.71. The difference between the coding sequence ratio (3.49%) and the ratio of mutations (4.8%) indicated that the LDT panel identified a relatively higher number of mutations. It was feasible to calculate TMB with LDT panel, which can be useful in clinical practice. Furthermore, a customized approach must be developed for calculating TMB, which differs according to cancer types and specific clinical settings.