• Journal of Life Science
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• v.12 no.2
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• pp.136-143
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• 2002

Jaboyangyeong-hwan (IAE) has been known as a traditional medicine for the treatment of debility, fatigue, and liver diseases. The hepatoprotective effect of the water extract of Jaboyangyeong-hwan was investigated against carbon tetrachloride ($CCl_4$)-induced hepatic damage. A single intraperitoneal injection of $CCl_4$produced liver damage in rats as manifested by the significant rise of aspartate aminotransferase (AST, alanine aminotransferase (ALT), and alkaline phosphatase (ALP) in serum as compared to those of untreated normal group. Pretreatments of rats with the JAE extract (300, 600, and 1200 mg/kg for 7 days) were significantly reduced AST, ALT, and ALP levels compared with $CCl_4$-treated control group. Treatment of rats with $CCl_4$led to significantly increase in lipid peroxidation and significantly decrease in cytochrome P450 and P450 reductase. The oral administration of the JAE extract significantly inhibited the accumulation of microsomal thiobarbituric acid reactive substance (TBARS) and increased the cytochrome P450 and P450 reductase activity. All these biochemical alterations resulting from $CCl_4$administration were inhibited by the pretreatment with JAE extract. These results suggest that JAE water extract can be useful as a hepatoprotective agent.

• International Journal of Highway Engineering
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• v.14 no.1
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• pp.17-24
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• 2012

This study evaluated the performance of Korean epoxy asphalt mixtures using several laboratory tests. Four types of epoxy asphalt mixtures were manufactured based on 13mm dense graded asphalt mixtures: three Korean and one Japanese epoxy asphalt mixtures where 20% or 40% of asphalt binder was replaced by epoxy resins. Curing time was determined as 3 and 6 hours for the mixtures containing 40% and 20% of epoxy resins, respectively. From the laboratory tests including wheel tracking, indirect tension fatigue, bending beam, and moisture susceptibility tests, it was concluded that the epoxy asphalt mixtures had superior performance than conventional asphalt mixtures except moisture susceptibility. Also, the performance of the Korean epoxy asphalt mixtures was comparable to the Japanese mixtures. Thermal coefficient, bond strength, and indirect tension tests were conducted to examine the applicability of the Korean epoxy asphalt mixtures to concrete repair. Its adhesion was strong enough to be bonded to surrounding concrete materials and its tensile strength was comparable to the concrete, but thermal expansion coefficient was 5 times greater than the surrounding concrete.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.1D
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• pp.73-79
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• 2006

A major purpose of this study is to develop high modulus asphalt mixtures for perpetual asphalt pavements which can save maintenance cost by increasing the design and performance periods of the pavements. Various physical and mechanical laboratory tests are performed for the high modulus asphalt binder developed in this study. The test results show that the properties of the high modulus binder are similar to those of the French high modulus binders. In addition to the binder tests, various performance tests are conducted for the high modulus and conventional mixtures. The dynamic modulus test results indicate that the dynamic modulus values of the high modulus mixtures are higher than those of the conventional mixtures by 10~15% at $5^{\circ}C$, 20~25% at $15^{\circ}C$ and 100% at $30^{\circ}C$. It is observed from the performance tests that the high modulus mixtures yield better fatigue, rutting and moisture damage performance than the conventional mixtures.

• Journal of Dental Rehabilitation and Applied Science
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• v.18 no.3
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• pp.145-155
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• 2002

The results of the present feasibility study are summarized as follows, 1. The three unit bridge of knitted material and UD fibre reinforcement has both the rigidity and the strength against a vertical occlusal load of 75N. 2. Stress concentration at the junctional area between the bridge and the abutments, i.e. between the pontic and the knitted caps was observed. In the case of the bridge with reinforcement straps, it was partly shown that the concentration problem could be improved by simply increasing the fillet size at the area. Further refining in the surface of the junctional area will be needed to ensure a further improvement in the stress distribution. This will require some trade off in the level of the stress and the available space. A parametric study will help to decide the appropriate size of the fillet. 3. Design refinement is a must to improve the stress distribution and realize the most favourable shape in terms of fabrication. The current straight bar with a constant cross section area can be redesigned to a tapered shape. The curve from the dental arch should also be placed on the pontic design. In accordance with design refinement, the resistance of the bridge frame to other load cases should be evaluated. 4. Although not included in the present feasibility study, it is estimated that bridges of the anterior teeth can be made strong enough with the knitted material without further reinforcement using unidirectional materials. In this regard, a feasibility study on design concepts and stress analysis for 3, 4, 5 unit bridge is suggested. 5. Two types of bridge were analysed in terms of fatigue. The safe life design concept, i.e. fatigue design concept, looks reasonable for the bridge where if cracks should form and propagate there is virtually nothing a dentist to do. The bridge must be designed so that no crack will be initiated during the life span. In the case of crowns, however, if constructed with composite resin with knitted materials, it might be possible to repair them, which in general is impossible for crowns of PFM or of metal. Therefore for composite resin crowns, a damage tolerance design concept can be applied and reasonably higher operational stresses can be allowed. In this case, of course, a periodic inspection program should be established in parallel. 6. Parts of future works in terms of structural viewpoint which need to be addressed are summarized as the following: 1) To develop processing technology to accommodate design concepts; 2) More realistic modelling of the bridge and analysis-geometry and loading condition. Thickness variation in the knitted material, taper in the pontic, design for anterior tooth bridge, the effect of combined loads, etc, will need to be included; 3) To develop appropriate design concepts and design goals for the fibre composite FPD aiming at taking the best advantage of knitted materials, including the damage tolerance design concept; 4) To develop testing method and perform test such as static ultimate load test, fatigue test, repair test, etc, as necessary.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.48 no.2
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• pp.127-134
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• 2020

High supersonic aircraft are exposed to high temperature environments by aerodynamic heating during supersonic flight. Thermal protection system structures such as double-panel structures are used on the skin of the fuselage and wings to prevent the transfer of high heat into the interior of an aircraft. The thin-walled double-panel skin can be exposed to acoustic loads by supersonic aircraft's high power engine noise and jet flow noise, which can cause sonic fatigue damage. Therefore, it is necessary to examine the behavior of supersonic aircraft skin structure under thermal-acoustic load and to predict fatigue life. In this paper, we designed and fabricated thermal-acoustic test equipment to simulate thermal-acoustic load. Thermal-acoustic testing of the titanium specimen under thermal-acoustic load was performed. The analytical model was verified by comparing the thermal-acoustic test results with the finite element analysis results.

• Wind and Structures
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• v.28 no.5
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• pp.271-284
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• 2019

This paper describes the application of a novel virtual prototyping methodology to wind turbine blade design. Numeric modelling data and experimental data about turbine blade geometry and structural/dynamical behaviour are combined to obtain an affordable digital twin model useful in reducing the undesirable uncertainties during the entire turbine lifecycle. Moreover, this model can be used to track and predict blade structural changes, due for example to structural damage, and to assess its remaining life. A new interactive and recursive process is proposed. It includes CAD geometry generation and finite element analyses, combined with experimental data gathered from the structural testing of a new generation wind turbine blade. The goal of the research is to show how the unique features of a complex wind turbine blade are considered in the virtual model updating process, fully exploiting the computational capabilities available to the designer in modern engineering. A composite Sandia National Laboratories Blade System Design Study (BSDS) turbine blade is used to exemplify the proposed process. Static, modal and fatigue experimental testing are conducted at Clarkson University Blade Test Facility. A digital model was created and updated to conform to all the information available from experimental testing. When an updated virtual digital model is available the performance of the blade during operation can be assessed with higher confidence.

• Structural Engineering and Mechanics
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• v.41 no.2
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• pp.231-242
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• 2012

This research work aims to develop an optimal design using Finite Element (FE) and Genetic Algorithm (GA) methods to replace the traditional concrete and timber material by a Synthetic Polyurethane fibre glass composite material in railway sleepers. The conventional timber railway sleeper technology is associated with several technical problems related to its durability and ability to resist cutting and abrading action of the bearing plate. The use of pre-stress concrete sleeper in railway industry has many disadvantages related to the concrete material behaviour to resist dynamic stress that may lead to a significant mechanical damage with feasible fissures and cracks. Scientific researchers have recently developed a new composite material such as Glass Fibre Reinforced Polyurethane (GFRP) foam to replace the conventional one. The mechanical properties of these materials are reliable enough to help solving structural problems such as durability, light weight, long life span (50-60 years), less water absorption, provide electric insulation, excellent resistance of fatigue and ability to recycle. This paper suggests appropriate sleeper design to reduce the volume of the material. The design optimization shows that the sleeper length is more sensitive to the loading type than the other parameters.

• Structural Monitoring and Maintenance
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• v.2 no.1
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• pp.65-75
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• 2015

Among the destruction instances of half-through arch bridges, the shorter hangers are more likely to be ruined. For a thorough investigation of the hanger system durability, we have studied vehicle impact effect on hangers with vehicle-bridge coupling method for a half-through concrete-filled-steel-tube arch bridge. A numerical method has been applied to simulate the variation of dynamic internal force (stress) in hangers under different vehicle speeds and road surface roughness. The characteristics and differences in impact effect among hangers with different length (position) are compared. The impact effect is further analyzed comprehensively based on the vehicle speed distribution model. Our results show that the dynamic internal force induced by moving vehicles inside the shorter hangers is significantly greater than that inside the longer ones. The largest difference of dynamic internal force among the hangers could be as high as 28%. Our results well explained a common phenomenon in several hanger damage accidents occurred in China. This work forms a basis for hanger system's fatigue analysis and service life evaluation. It also provides a reference to the design, management, maintenance, monitoring, and evaluation for this kind of bridge.

• Structural Engineering and Mechanics
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• v.72 no.1
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• pp.31-41
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• 2019

Structural integrity assessment of piping components is of paramount important for remaining life prediction, residual strength evaluation and for in-service inspection planning. For accurate prediction of these, a reliable fracture parameter is essential. One of the fracture parameters is stress intensity factor (SIF), which is generally preferred for high strength materials, can be evaluated by using linear elastic fracture mechanics principles. To employ available analytical and numerical procedures for fracture analysis of piping components, it takes considerable amount of time and effort. In view of this, an alternative approach to analytical and finite element analysis, a model based on relevance vector machine (RVM) is developed to predict SIF of part through crack of a piping component under fatigue loading. RVM is based on probabilistic approach and regression and it is established based on Bayesian formulation of a linear model with an appropriate prior that results in a sparse representation. Model for SIF prediction is developed by using MATLAB software wherein 70% of the data has been used for the development of RVM model and rest of the data is used for validation. The predicted SIF is found to be in good agreement with the corresponding analytical solution, and can be used for damage tolerant analysis of structural components.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.33 no.10
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• pp.1177-1186
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• 2009

High temperature steam pipes of thermal power plant are subject to a severe thermal range and usually operates well into the creep range. Cyclic operation of the plant subjects the piping system to mechanical and thermal fatigue damages. Also, poor or malfunctional supports can impose massive loads or stress onto the piping system. In order to prevent the serious damage and failure of the critical piping system, various inspection methods such as visual inspection, computational analysis and on-line piping displacement monitoring were developed. 3-dimensional piping displacement monitoring system was developed with using the aluminum alloy rod and rotary encoder sensors, this system was installed and operated on the high temperature steam piping of "Y" thermal power plant successfully. It is expected that this study will contribute to the safety of piping system, which could minimize stress and extend the actual life of critical piping.