• 여성건강간호학회지
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• 제26권1호
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• pp.49-60
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• 2020

Purpose: Infertile women experience various physical, psychological, and relational problems that affect their infertility-related quality of life (QoL). This study investigated infertile women's infertility-related QoL with the goal of identifying how it is influenced by fatigue, depression, and marital intimacy. Methods: A sample of 140 infertile women was surveyed in a cross-sectional study. Data were collected from February to April 2018 using self-report structured questionnaires at three infertility clinics located in Jeonju, Korea. Data were analyzed using the independent t-test, analysis of variance, Pearson correlation coefficients, and stepwise multiple regression analysis in SPSS for Windows version 25.0. The subjects agreed to complete a face-to-face interview, including administration of the Fatigue Severity Scale, Depression Anxiety Stress Scale-21, Marital Intimacy Scale, and the Fertility Quality of Life tool. Results: The mean age of the participants was 35.6±4.3 years. Infertility-related QoL was negatively correlated with fatigue (r=-.42, p<.001) and depression (r=-.56, p<.001), and positively correlated with marital intimacy (r=.30, p<.001). Multiple regression analysis showed that depression (β=-0.44, p<.001), fatigue (β=-0.27, p<.001), and husband's attitude (β=-0.19, p=.007) had significant effects on the QoL of infertile women, accounting for 40.5% of the variance in infertility-related QoL. Conclusion: The study provides insights into how infertile women's infertility-related QoL was influenced by depression, fatigue, and their husbands' attitudes regarding infertility treatment. To improve infertile women's infertility-related QoL, healthcare providers should consider developing strategies to decrease depression and fatigue in infertile women and to address their husbands' attitudes.

• 대한한방내과학회지
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• 제42권5호
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• pp.738-745
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• 2021

Objective: This study investigated the efficacy of using Nokyonggunbi-tang and other Korean medical treatments for a patient with consumptive disease and chronic fatigue. Methods: A 59-year-old female patient with fatigue, headache, dizziness, and neck pain due to consumptive disease and chronic fatigue was treated with herbal medicine (Nokyonggunbi-tang), together with acupuncture, pharmacopuncture, cupping, and chuna manual therapy, for 22 days. The treatment effects on the pain were evaluated using the scores for the Fatigue Severity Scale (FSS), European Quality of Life Five Dimensions (EQ-5d) Scale, Neck Disability Index (NDI), and Numerical Rating Scale (NRS). Results: Following treatment, the patient showed a decrease in the FSS, NDI, and NRS scores and an improvement in the EQ-5d score. Conclusions: Nokyonggunbi-tang and Korean medical treatment significantly improved fatigue symptoms in a patient with no substrate disease.

• 대한한의학회지
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• 제34권3호
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• pp.119-125
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• 2013

Objectives: Medically unexplained fatigue includes chronic fatigue syndrome (CFS) and idiopathic chronic fatigue (ICF). These disorders quite impair quality of life while no effective therapies exist. Therefore, patients with CFS or ICF frequently choose treatments based on traditional Korean medicine. The study aimed to analyze characteristic of patients visiting an Oriental clinic with CFS or ICF. Methods: Patients who met criteria for CFS or ICF were enrolled in this study, from March 2011 to Jun 2013. Clinical information focused on symptom differentiation and Sasang constitution was analyzed. Pearson's chi-square test was used to compare the frequency among sub-groups. Results: In total, 77 patients (49 male and 28 female) were diagnosed with CFS (17 male and 13 female) or ICF (32 male and 15 female). The symptom differentiation was 37.7%, 26.0%, 13.0%, and 23.3% for "Qi deficiency of both spleen and lung (脾肺氣虛)", "Yin deficiency of both liver and kidney (肝腎陰虛)", "Blood deficiency of both heart and spleen (心脾血虛)" and "Yang deficiency of both spleen and kidney (脾腎陽虛)", while Sasang constitutional distribution was 59.7%, 22.1% and 18.2% Soeumin, Taeumin and Soyangin, respectively. The fatigue severity was notably different between CFS ($63.7{\pm}12.1$) or ICF ($52.2{\pm}15.3$) according to the Chalder fatigue scale (10-point scale for eleven questions). There was statistical significance regarding symptom differentiation and Sasang constitution (p < 0.05). Conclusions: In the process of traditional Korean medicine-based development of therapeutics for patients with chronic fatigue or related conditions, this report can serve as reference data.

• 자동차안전학회지
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• 제12권3호
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• pp.27-33
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• 2020

In this paper, the process of predicting efficient durability performance for vibration durability test of automobile parts using vibration test load on automobile fuel tank is presented. First of all, the common standard load that can be applied to the initial development process of the automobile was used for the fuel tank and the vulnerability of the fuel tank to the vibration fatigue load was identified through frequency response analysis. In addition, the vulnerability of the fuel tank was re-enacted through vibration durability test results, and the scale factor was applied to the standard load. In order to predict the vibration durability performance required for detailed design, vibration fatigue analysis was performed on the developed vehicle with the frequency of vibration severity equivalent to the durability test, and the vulnerability and life span of the fuel tank were identified through the process of applying weights to these selected standard loads, thereby reducing the test time of the development vehicle.

• 대한한방내과학회지
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• 제38권5호
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• pp.719-726
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• 2017

Objectives: This case report presents improvement of fatigue and tingling symptoms in a patient with Guillain-Barre syndrome (GBS) after receiving Korean medical treatment. Methods: The patient was treated for 35days with the herbal medicine Hyangsayangwi-tang-gamibang and acupuncture. The effects of treatments were measured with fatigue severity scale (FSS) and numeric rating scale (NRS). Results: The clinical symptoms of the GBS patient were improved considerably after Korean medicine treatment. Conclusions: The herbal medicine Hyangsayangyi-tang-gaimibang and acupuncture could be effective for treatment of symptoms of fatigue and tingling in patients with GBS, but more studies are needed to confirm the present results.

• Journal of Korean Biological Nursing Science
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• 제21권3호
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• pp.188-198
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• 2019

Purpose: The purpose of this study was to examine the effect of laughter therapy on depression, anxiety, fatigue, and quality of sleep in gastrointestinal cancer survivors. Methods: This study was a randomized controlled trial. We compared the effect of laughter therapy with usual care only in post chemotherapy gastrointestinal patients. Outcomes included changes in depression and anxiety (according to the Hospital Anxiety and Depression Scale), fatigue (according to the Fatigue Severity Scale), and quality of sleep (according to the Verran & Synder-Halpern Sleep Scale). Data was collected July 2015 through January 2016. Seventy nine participants who agreed to participate in this study were randomized to either the experimental group (n= 40) or the control group (n= 39). Therapy included eight sessions (60 minutes each, once weekly). Data were analyzed using the Windows SPSS 22.0 program. Results: Laughter therapy was effective in reducing fatigue (p= .019) and increasing satisfaction of sleep (p= .030). There were no differences between the groups after therapy for depression (p= .129) and anxiety (p= .200). Conclusion: Results of this study indicate that laughter therapy may be an effective nursing intervention for improving the health status of gastrointestinal cancer survivors after chemotherapy.

• 대한상한금궤의학회지
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• 제11권1호
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• pp.47-61
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• 2019

Objective : This study was performed to report two cases diagnosed with the Shanghanlun disease pattern identification diagnostic system (DPIDS) and treated with Jeodang-tang. Methods : Based on DPIDS, we analyzed two cases treated with Jeodang-tang. Results : In the first case, the bipolar depression rating scale (BDRS) score improved from 44 to 13. In the second case, the fatigue severity scale (FSS) score improved from 55 to 24. Conclusions : In Shanghanlun, Jeodang-tang may not only treat pattern/syndrome of blood stasis but also many other diseases.

• 성인간호학회지
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• 제29권1호
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• pp.87-97
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• 2017

Purpose: The purpose of this study was to investigate the relationship among sleep quality, heart rate variability (HRV), fatigue, depression, and anxiety reported by Korean adults. Methods: A cross-sectional study of 208 adults aged 20~60 years was conducted using a short-term HRV analysis and self-reported questionnaires of Pittsburgh Sleep Quality Index (PSQI), Fatigue Severity Scale, Beck Depression Inventory, and State Trait Anxiety Inventory. Results: Subjects with good sleep quality (PSQI $score{\leq}5$) had higher HRV total power (t=2.03, p=.043) and high-frequency (t=2.04, p=.043) with lower fatigue (t=-4.08, p<.001), depressive mood (t=-3.66, p<.001), and trait anxiety (t=-3.84, p<.001) than subjects with poor sleep quality. Poor sleep quality was negatively correlated with HRV total power (r=-.17, p=.016), high-frequency (r=-.14, p=.049), and positively fatigue (r=.39, p<.001), depression (r=.44, p<.001), state anxiety (r=.23, p=.001) and trait anxiety (r=.34, p<.001). Conclusion: The results indicated that sleep quality is correlated with HRV which reflects the activities of the autonomic nerve system, fatigue, depression, and anxiety in adults.

• 대한통합의학회지
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• 제6권4호
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• pp.1-13
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• 2018

Purpose : The purpose of this study has been performed to find the relationship between seafarers' cumulative fatigue and stress by evaluating autonomic nervous functions and the results of surveys conducted using questionnaires. Methods : The subjects were seafarers working on various ships (home trade ships) of South Korea, who were healthy adults without any diseases, as confirmed through preliminary surveys were recruited through simple random sampling. A device that measures autonomic nervous functions by analyzing heart rate variability, which is also used often in clinical diagnoses and studies at universities, university hospitals, and general hospitals was used to measure the seafarers' cumulative fatigue and stress. Pearson's correlation analyses were also conducted to test the relationship between cumulative fatigue and stress measured by evaluating autonomic nervous functions and the results of surveys conducted with questionnaires. Results : There was no correlation between mean cumulative fatigue measured for each ship type and seafarers position through autonomic nervous functions evaluation and fatigue severity scale (FSS). There also was no correlation between the mean levels of stress measured for each ship type and seafarers position through autonomic nervous functions evaluation and survey scores of Korean occupational stress scale (KOSS). Conclusion : Therefore, in order to prevent man-made accidents in the sea among seafarers working with irregular port entry/departure schedules and under environments involving continued vibration, noises, and shaking, it is necessary to analyzed cumulative fatigue and stress scientifically and objectively, such as through autonomic nervous functions evaluation rather than through surveys.

• 대한예방한의학회지
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• 제26권3호
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• pp.97-108
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• 2022

Objectives : The purpose of this study is to confirm the efficacy and safety of Gongjin-dan and Ssanghwatang for chronic fatigue. Methods : A total of 90 people, between 19 and 65 years old, will be recruited to participate in a randomized, double-blind, and placebo-controlled a clinical trial. Participants in the Gongjin-dan group will take one pill of Gongjin-dan along with three packs of placebo oral liquid Ssanghwa-tang per day for 4 weeks. Participants in the Ssanghwa-tang group will take three packages of liquid Ssanghwa-tang and one placebo Gongjindan pill per day for 4 weeks. In the placebo group, participants will take one pill of placebo Gongjin-dan and three packs of placebo liquid Ssanghwa-tang per day, for 4 weeks. Outcomes will be measured at the baseline, 4^th week, and 6^th week. The primary outcome is the change in the Fatigue Severity Scale (FSS). Secondary outcomes are the change of Multidimensional Fatigue Inventory-20 (MFI-20), Chalder Fatigue Scale (CFQ), Short-Form 36 Health Survey (SF-36), Korean Version of Schedule of Fatigue and Anergy/General Physician (SOFA/GP), Glucose, Lactate, Ammonia, Free Fatty Acid (FAA), d-ROMs&BAP, Selenium, and Cortisol. Results : This trial was approved by the institutional review board of Pusan National University Korean Medicine Hospital (registry number: PNUKHIRB 2021-10-005). Recruitment opened in November 2021 and is supposed to be completed by December 2022. Conclusions : This trial will provide clinical information to determine the efficacy and safety of Gongjindan and Ssanghwa-tang for chronic fatigue.