• The Bulletin of The Korean Astronomical Society
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• v.37 no.2
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• pp.207.1-207.1
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• 2012

One of the key aspects of the upcoming Ultra-Fast Observatory (UFFO) Pathfinder for Gamma-Ray Bursts(GRBs) identification will be the UFFO Burst Alert & Trigger Telescope(UBAT), based on a novel space telescope technique. The UBAT consists of coded mask, hopper, and detector module(DM). The UBAT DM consists of YSO crystal arrays, multi-anode photo mulipliers, and readout electronics. We will present the design and construction of the UBAT DM, and the response of the UBAT DM to X-ray sources.

• Polymer(Korea)
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• v.32 no.3
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• pp.199-205
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• 2008

In this study, we fabricated poly (lactide-co-glycolide) (PLGA) scaffold modified with small intestinal submucosa (SIS) as a drug delivery matrix of bioactive molecules. SIS derived from the submucosa layer of porcine intestine has been widely used as biomaterial because of low immune response. PLGA scaffold was prepared by the method of solvent casting/salt leaching. Novel composite scaffolds of SIS/PLGA were manufactured by simple immersion method of PLGA scaffold in SIS solution under vacuum. SEM observation shows that PLGA and SIS/PLGA scaffolds have interconnective and open pores. Especially, SIS/PLGA scaffold showed that micro-sponge of SIS with interconnected pore structures were formed in the pores of PLGA scaffold. In order to assay release profile of proteins, we manufactured FITC conjugated BSA loaded PLGA and SIS/PLGA scaffold. And the release amount was identified by fluorescence intensity using the fluorescence spectrophotometer. The initial burst of BSA containing SIS/PLGA scaffolds was lower than that of PLGA scaffolds resulting in constant release. And release of BSA in SIS/PLGA scaffold was fast and incremental because of the increased content of BSA. In conclusion, we confirmed that penetrated SIS solution prevented the initial burst of BSA and PLGA modified with SIS scaffold is useful as protein carriers with controlled release pattern.

• The Korean Journal of Physiology
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• v.15 no.2
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• pp.83-89
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• 1981

This study was conducted to investigate the effect of the ingestion of rice and hamburger meals upon the plasma gastrin concentration in normal human subjects in Korea. Eight normal human subjects including male and female with the mean age of 28 years (range: 20-40 years) were studied. After an overnight(about 15 hrs) fast each subject ingested a rice meal and a hamburger meal on different days. The rice meal consisted of 250 g boiled rice, 50 g vegetables and 200 ml barley tea, corresponding to 6.8 g protein, 0.5 g fat and 81g carbohydrate and the hamburger meal consisted of 200 g hamburger, 50 g vegetables ana 200 ml milk, corresponding to 43 g protein, 43 g fat and 9 g carbohydrate. The venous blood samples were drawn before and after the ingestion of the test meal at the following times: -30, 0, 15, 30, 45, 60, 90, and 120 min, for measurement of gastrin by radioimmunoassay. The following results were obtained : 1) Plasma gastrin concentration in response to the ingestion of the rice or the hamburger meal increased significantly compared with the concentration in fasting state. 2) The increase of the plasma gastrin concentration after the hamburger meal was significantly higher than that after the rice meal. 3) There was a significant linear correlation between the postprandial peak plasma gastrin concentration after the rice meal and the concentration after the hamburger meal in each subject. It is inferred from the above results that a carbohydrate meal as well as a protein meal has a stimulatory effect on gastrin release in normal human subjects.

• Journal of the Korean Institute of Intelligent Systems
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• v.22 no.3
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• pp.361-366
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• 2012

This paper presents speed control of an electric motorcycle using a fuzzy controller. The electric motorcycle required to meet not only fast throttle response but also stability, when it is on a cruise. However, a 1.5KW (50cc) electric motorcycles selling in the current market are difficult to cruise under the following conditions which are occupant's weight, load weight, wind resistance and road conditions (dirt roads, asphalt road). Because of these reasons, the rapid speed changing occurs in uphill and downhill road. To solve these problems, The input value for Improved fuzzy controller use the speed error and error variance. The output value for improved fuzzy controller uses Q-axis of the motor controlled variable. The D-axis of the motor output for improved fuzzy control uses D-axis controlled variable in proportional to Q-axis controlled variable. Improved fuzzy controller drives the electric motorcycle equipped with IPMSM. The control subject used in this paper is a 1.5KW electric motorcycle equipped with improved fuzzy controller that was used to control the motor speed. To control IPMSM Type of motor torque, D, Q-axis current controller was used. The Fuzzy controller using the proposed algorithm is demonstrated by experimental hardware simulator.

• Journal of Biomedical Engineering Research
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• v.22 no.6
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• pp.487-496
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• 2001

In this study, a galvanic stimulator providing bipolar mode controlled by a PIC(peripheral interface controller) was constructed to evaluate vestibular function The maximum load and maximum current intensity of the constant current source were 3$k\Omega$ and 5mA. respectively. and it could Produce DC, sine wavers. or Pulse waves. Eve movements of 20 normal subjects by galvanic stimulation were analyzed using a commercial videooculogragh. During stimulating with DC for 30 sec. we recorded the response of eye movement with current intensity of 0.75. 1 2, and 3 mA. Nystagmus occurred to all the subjects when the galvanic stimulus intensity was larger than 2 mA. Average SPV(slow Phase eye movement velocity) and the number of nystagmus increased from 7.1 to 4.8 deg/sec and from 17 to 48, respectively, when the stimulus current increased from 0.75 to 3 mA. All the fast eye movement of the nystagmus were the direction of the negative electrode. The asymmetry which means the difference between right- and left-eye movements decreased when the stimulus intensity increased. It is expected that this study would be useful in evaluating vestibular function and in studying basic Physiology mechanism of vestibular ocular reflex by galvanic stimulus .

• Journal of Biomedical Engineering Research
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• v.18 no.3
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• pp.273-283
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• 1997

Electrogastrography(EGG), the cutaneous recording of the myoelectrical activity of the stomach using surface electrodes, is attactive due to its non-invasiveness. Despite many attempts made over the decades, analysis of surface EGG has not led to identification of contraction-related electrical response activity of the stomach that would help the clinician to diagnose motility disorders of the stomach. We propose feasible methods to detect the gastric contraction by spectrum analysis and vector analysis of the surface EGG signal. A running spectral analysis(RSA) based on the fast Fourier transform (FFT) was applied to the filtered EGG signal. The powers of dominant frequency and its harmonics were compared with gastric contraction signals such as the strain gauge signal from the gastric serosa in dog or the antropyloric pressure in human. And we also carried out vector analysis of the filtered EGG signals obtained from three paired electrodes. The amplitude and direction of the calculated EGG vector were analyzed and compared with the gastric contraction signals. From the spectrum analysis, we found that the increase of the power of the first harmonic of the dominant frequency was highly correlated with the gastric contraction. And from the vector analysis of the EGG signal, we found a typical change of the amplitude and direction of the EGG vector, which can indicate occurrences of the gastric contraction.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.5
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• pp.1-9
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• 2016

Railroad bridges account for 25% of the entire high-speed rail network. Railway bridges are subject to gradual structural degradation or fatigue accumulation due to consistent and repeating excitation by fast moving trains. Wireless sensing technology has opened up a new avenue for bridge health monitoring owing to its low-cost, high fidelity, and multiple sensing capability. On the other hand, measuring the transient response during train passage is quite challenging that the current wireless sensor system cannot be applied due to the intrinsic time delay of the sensor network. Therefore, this paper presents a framework for monitoring such transient responses with wireless sensing systems using 1) real-time excessive vibration monitoring through ultra-low-power MEMS accelerometers, and 2) post-event time synchronization scheme. The ultra-low power accelerometer continuously monitors the vibration and trigger network when excessive vibrations are detected. The entire network of wireless smart sensors starts sensing through triggering and the post-event time synchronization is conducted to compensate for the time error on the measured responses. The results of this study highlight the potential of detecting the impact load and triggering the entire network, as well as the effectiveness of the post-event time synchronized scheme for compensating for the time error. A numerical and experimental study was carried out to validate the proposed sensing hardware and time synchronization method.

• Korean Security Journal
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• no.61
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• pp.307-332
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• 2019

Recently, our society has been changing its population structure due to low birth rate along with the extension of life span due to the development of medical environment and improvement of living environment. It was not long before the population became older, and the problem of the elderly was amplified by generational conflict. The current generation of senior citizens could not afford to prepare for their own retirement income due to their children's education, marriage and housing problems, and is a generation alienated from the benefits of public income security. In addition, not only are they in poverty with rapid industrialization, informatization and economic instability, but they are also threatened with livelihood. The increase in elderly crimes arising from the elderly, who are less adaptable to our society dominated by materialism, is being highlighted as a new social issue. In this study, we are going to analyze the causes of violent and violent senior citizens' crimes in quality along with quantitative growth, and present criminal situations and preventive measures using 10 years of data, judging that this is a time when a national response is needed through a social discussion on crimes committed by senior citizens in our society, where the pace of aging is unprecedentedly fast in the world In order to achieve this research objective, various opinions and statistical data of our society where the standards of senior citizens are changing were reviewed, and analysis of crimes was conducted on literature utilizing data of the Supreme Public Prosecutor's Office, the National Police Agency, and the National Statistical Office, recent press releases, and existing research materials. In this study, we will diagnose crimes committed by senior citizens in various aspects, including the characteristics of the elderly and the view of the elderly in the present society, and explore the direction of development for the prevention of future crimes as well.

• Journal of Korea Water Resources Association
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• v.38 no.8 s.157
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• pp.645-653
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• 2005

Water cycle analysis in the Cheonggyecheon watershed(river length: 13.75 km, area: $50.96\;km^2$) was performed using WEP model, a physically based distributed rainfall-runoff model. As the application results of the model, the hydrological characteristics of the Cheonggyecheon watershed are significantly consistent with those of a typical urbanized watershed. The direct runoff from the watershed was larger and the evapotranspiration. was lower, and the response of runoff to rainfall was occurred very fast, as compared to forest watersheds. The river channel routing simulation results are similar to the change pattern and scale of the field data. The possible supply period of instream flow from Cheonggyecheoon watershed itself was estimated using WEP. According to the WEP simulation results for the annual water balance of the Cheonggyecheon watershed in 2002, the amount of direct runoff, infiltration and evapotranspiration were 830 mm, 388 mm and 397 mm respectively for an annual precipitation of 1,388 mm. The runoff to rivers was 1,288 mm. And the proportion of direct runoff, intermediate runoff and groundwater runoff were $67.6\%,\;12.7\%$ and $19.7\%$ respectively.

• Journal of Life Science
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• v.23 no.2
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• pp.324-331
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• 2013

The addition and removal of N-acetylglucosamine (GlcNAc) molecules on serine or threonine residues of a protein is called O-GlcNAcylation. This post-translational modification occurs on both cytoplasmic and nuclear protein, and is fast and reversible as comparable to phosphorylation. In contrast to the phospho-signaling cycles, this emerging moon-lightening signaling is cycled by only two enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). The simple machinery is a good evolutionary adaptation of a cell for quick accommodation to continuously fluctuating intra- and extracellular microenvironments. Rather than "switching" on or off a specific proteins - this would be done by phosphorylation where numerous specific kinases and phosphatases are involved - O-GlcNAcylation would play a "rheostat" which would be much more delicately increase or decrease the efficacy of signal transductions in response to cellular nutrient and stress conditions. Interestingly, recent evidence indicates that O-GlcNAc is further modified by phosphorylation. The O-GlcNAc-P will upgrade the modulation efficiency of cellular processes to continuous 'analogue' level. So far, only one protein AP180 was reported to have O-GlcNAc-P on Thr310. But, proteomic data from our laboratory indicate that there are multiple O-GlcNAc-P proteins, constituting "O-GlcNAc-P'om". This will focus on the possibility of existence of "O-GlcNAc-P'om".