• Journal of Korean Medicine Rehabilitation
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• v.20 no.4
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• pp.1-15
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• 2010

Objectives : This study was performed to evaluate the effects of Hwangryunhaedok-tang(Huanglianjiedu-tang HHT) water extract on locomotor dysfunction induced by spinal cord injury(SCI) in rats. Methods : SCI was induced by mechanical contusion following laminectomy of 10th thoracic vertebra in Sprague-Dawley rats. HHT was orally given once a day for 14 days after SCI. Neurological behavior was examined with the Basso-Beattie-Bresnahan locomotor rating scale. Tissue damage and nerve fiber degeneration were examined with cresyl violet and luxol fast blue staining. Using immunohistochemisty, cellular damage to neurons and nerve fibers were examined against Bax and MAP-2. As inflammatory response markers, iNOS and COX-2 expressions were also examined. Results : 1. HHT ameliorated the locomotor dysfunction of the SCI-induced rats. 2. HHT attenuated the reduction of motor neurons in the ventral horn of the SCI-induced rat spinal cord. 3. HHT significantly reduced the number of Bax positive cells in the peri-lesion of the SCI-induced rat spinal cord. 4. HHT attenuated the reduction of MAP-2 positive cells in the peri-lesion of the SCI-induced rat spinal cord. 5. HHT significantly reduced the number of iNOS and COX-2 positive cells in the peri-lesion of the SCI-induced rat spinal cord. Conclusions : These results suggest that HHT improves the locomotor dysfunction of SCI by protecting motor neurons from cell death through anti-inflammatory effect.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.646-661
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• 2020

Technological innovations and fast-growing new internet businesses are changing the paradigm of traditional business management, having various impacts on society. The development of internet technology is also increasing the adverse effects on technological innovation, and in particular, cybercrime related to computers continues to increase with each technological innovation. The purpose of this study is to construct a cybercrime business model (CBM) by using the business model canvas (BMC) theory for cybercrime in order to reduce cybercrime, and this model is applied and analyzed based on types of Korean cybercrimes. For this study, a systematic literature review was conducted to determine the components of cybercrime, and 60 relevant documents were classified through a keyword-based literature search. Besides, qualitative research in the classified literature has led to the derivation of cybercrime into 18 sub-blocks and nine building blocks. This study applies BMC theory to this derivation of cybercrime and builds the CBM through proper redefinition. Lastly, the developed CBM could be applied to cybercrime in Korea to help cyber incident-response staff understand cybercrimes analytically. This study contributes to the development of a new analysis framework that can reduce cybercrime.

• Journal of Distribution Science
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• v.16 no.12
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• pp.105-113
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• 2018

Purpose - This research is intended to suggest ways to enhance customers' satisfaction with service recovery. For this purpose, this study investigated the relationships among perceived justice (distributive, procedural, interactional justice) of service recovery efforts, perceived authenticity of service recovery efforts, the intention to follow advice, and the satisfaction with service recovery. Research design, data, and methodology - This research developed a structural equation model in which the perceived justice (distributive, procedural, interactional justice) and the perceived authenticity are predictors, the satisfaction with service recovery is a dependent variable, and the intention to follow advice is a moderator between the perceived justice (distributive, procedural, interactional justice) and the satisfaction with service recovery. Data were collected from visitors of fast food restaurants in Seoul, Gyeonggi province, and Kangwon province. A total of 330 questionnaires were distributed and 295 responses were collected indicating a response rate of 89.3%. After deleting data having missing value, 288 samples were used for analysis. SPSS 21.0 and AMOS 21.0 were used to test the reliability, validity, model fit, and hypotheses. Results - Empirical results showed that perceived justice, perceived distributive justice, and perceived authenticity had a positive influence on the satisfaction with service recovery. These results indicated that the more highly customers perceived the justice, distributive justice and the authenticity of service recovery efforts, the more they were satisfied with service recovery. And these influences were moderated by the intention to follow advice. Specifically, influences of the perceived justice, the perceived distributive justice, and the perceived authenticity on the satisfaction with service recovery were bigger for people with high intention to follow advice than people with low intention to follow advice. Conclusions - This research contributed to the service recovery literature by showing how perceived justice (distributive, procedural, interactional justice) and perceived authenticity influence satisfaction with service recovery. Moreover, current study introduced the intention to follow advice as moderator of this influence and revealed the moderation role of the intention to follow advice between the perceived justice (distributive, procedural, interactional justice) and the satisfaction with service recovery. Managerially, these results suggested retailing companies some ways to recover from service failure.

• Proceedings of KOSOMES biannual meeting
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• 2018.06a
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• pp.16-16
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• 2018

2017년 겨울, 기록적인 한파로 인해 바다가 얼면서 인천 앞바다로 유빙이 유입되었다. 2013년 해상에서 유빙이 발견된 이후 약 5년만에 다시 유빙이 등장한 것이다. 중부청 소속 항공단 순찰결과에 따르면, 2018년 1월 12일 인천대교 인근 해상에서 최초로 발견된 이후 강화 연안, 영종도 북단 등 해상에서 광범위하고 불규칙한 형태로 유빙이 분포되어 있는 것으로 나타났다. 유빙의 문제점은 해상에서 선박의 안전운항을 저해하고 경비함정의 안전에 지장을 초래하며 기름 유출 시, 유출유의 거동 특성이 달라져 일반적인 방제방법의 적용이 곤란한 점이다. 이에 따라 해상에서의 해양오염사고 대응방안 마련을 위해 저온 및 유빙 유입 해상에서 유출유의 거동 특성을 알아보았다. 구분인자를 극한의 추위(Extreme Cold), 유빙(Pack Ice), 정착빙(Fast Ice) 3가지로 분류하여 기름의 성상변화 및 시사점을 살펴보고, 유출된 기름의 효율적 방제를 크게 3가지로 분류(기계적 봉쇄 및 회수, 화학적 분산제의 사용, 현장소각)하였다. 일반적인 방제장비를 저온 및 얼음분포 해상에서 사용 시 슬러시화 된 얼음으로 인해 유출유 회수가 어렵고, 동결온도에서 장비가 오작동할 우려가 있다. 이미 북유럽 국가에서는 극한의 추위와 얼음분포 해상에 특화된 방제장비를 도입하여 해양오염대비 대응을 하고 있다. 2003년 3월 발틱해에서 불법적으로 유출한 선저폐수를 특화 장비는 brush bucket 유회수기 이용 방제조치한 사례가 있으며, 2006년 5월 같은 장소에서 선박 침몰로 인한 기름 유출이 발생했을때도 brush bucket 유회수기 이용 방제조치를 하였다. 국내에도 이상 기후로 인해 기록적인 한파가 지속되면서 북극에서나 볼 법한 유빙들이 발견되고, 해양오염사고는 언제 어디서나 발생할 수 있으므로, 해양오염방제의 임무를 맡고 있는 국가기관으로써 특수한 환경까지도 고려하여 대응방안을 마련할 필요가 있다. 해양오염이 재난으로 인식되고 있는 상황에서, 그리고 지구온난화로 인한 이상기후변화가 지속되는 상황에서 겨울철 유빙 유입은 점점 더 많아질 수 있다. 본 연구에서는 자료나 방제경험이 부족하므로 일찌감치 북극항로 개발로 앞선 방제기술과 경험을 가지고 있는 북극이사회를 벤치마킹하여 관할 해역 특성에 맞는 대응방안을 고찰해 본다.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.8
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• pp.128-135
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• 2013

This paper presents a high dimming ratio Power-LED driver IC with high power which is capable of controlling LEDs. In order to accomplish a high dimming ratio LED driver, the preloading inductor current methodology is proposed for the power stage of the proposed method to achieve the fast transient response time during the Power-LED load switching. The information containing the current flowing on the LEDs can be utilized to predict the amount of the current on the inductor. The minimum LED current rising time of existing high dimming ratio Power-LED driver is limited by $3{\mu}s$, however that of the proposed high dimming ratio Power-LED driver is reduced about 1/10. The LED driver is implemented with 0.35um 60V BCDMOS 2-poly 4-metal process. The measurement results show that the proposed LED driver system features the minimum rising time as small as 240ns at the dimming frequency of 1KHz with a 12V of input voltage, nine white LEDs and 353mA of LED current. The LED rising time and power conversion efficiency of the chip are measured to be 240ns and 93.72%, respectively.

• Journal of Mechanical Science and Technology
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• v.18 no.9
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• pp.1680-1688
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• 2004

The information indicating device plays an important part in the information times. Recently, the classical CRT (Cathod Ray Tube) display is getting transferred to the LCD (Liquid Crystal Display) one which is a kind of the FPDs (Flat Panel Displays). The OLED (Organic Light Emitting Diodes) display of the FPDs has many advantages for the low power consumption, the luminescence in itself, the light weight, the thin thickness, the wide view angle, the fast response and so on as compared with the LCD one. The OLED has lately attracted considerable attention as the next generation device for the information indicators. And also it has already been applied for the outside panel of a mobile phone, and its demand will be gradually increased in the various fields. It is manufactured by the vapor deposition method in the vacuum state, and the uniformity of thin film on the substrate depends on the temperature distribution in the point-cell source. This paper describes the basic concepts that are obtained to design the point-cell source using the computational temperature analysis. The grids are generated using the module of AUTOHEXA in the ICEM CFD program and the temperature distributions are numerically obtained using the STAR-CD program. The temperature profiles are calculated for four cases, i.e., the charge rate for the source in the crucible, the ratio of diameter to height of the crucible, the ratio of interval to height of the heating bands, and the geometry modification for the basic crucible. As a result, the blowout phenomenon can be shown when the charge rate for the source increases. The temperature variation in the radial direction is decreased as the ratio of diameter to height is decreased and it is suggested that the thin film thickness can be uniformed. In case of using one heating band, the blowout can be shown as the higher temperature distribution in the center part of the source, and the clogging can appear in the top end of the crucible in the lower temperature. The phenomena of both the blowout and the clogging in the modified crucible with the nozzle-diffuser can be prevented because the temperature in the upper part of the crucible is higher than that of other parts and the temperature variation in the radial direction becomes small.

• Journal of Intelligence and Information Systems
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• v.9 no.1
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• pp.91-107
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• 2003

In the conduct of this study, a web-enabled healthcare system for the management of hypertension was implemented through a hyperlink-based inference approach. The hyperlink-based inference platform was implemented using the hypertext capacity of HTML which ensured accessibility, multimedia facilities, fast response, stability, ease of use and upgrade, and platform independency of expert systems. Many HTML documents, which are hyperlinked to each other based on expert rules, were uploaded beforehand to perform the hyperlink-based inference. The HTML documents were uploaded and maintained automatically by our proprietary tool called the Web-Based Inference System (WeBIS) that supports a graphical user interface (GUI) for the input and edit of decision graphs. Nevertheless, the editing task of the decision graph using the GUI tool is a time consuming and tedious chore when the knowledge engineer must perform it manually. Accordingly, this research implemented an automatic generator of the decision graph for the management of hypertension. As a result, this research suggests a methodology for the development of Web-enabled healthcare systems using the hyperlink-based inference approach and, as an example, implements a Web-enabled healthcare system for hypertension, a platform which performed especially well in the areas of speed and stability.

• The Korean Journal of Nuclear Medicine
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• v.30 no.3
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• pp.344-350
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• 1996

Purpose : Noninvasive imaging of tumor cell proliferation could be helpful in the evaluation of tumor growth potential and could provide an early assessment of treatment response. Radiolabeled thymidine, uridine and adenosine have been used to evaluate tumor cell proliferation. These nucleoside analogs are incorporated into DNA during proliferation. Iodine-131-Iodomethyluridine, an analog of Iodine-131-Iododeoxyuridine, is also involved in DNA/RNA synthesis. The purpose of this study was to develop Iodine-131-Iodomethylurdine and image tumor proliferation using Iodine-131-Iodomethyluridine. Materials and Methods : Radiosynthesis of Iodine-131-5-Iodo-2'-O-methyluridine (Iodine-131-Iodomethyluridine) was prepared from 10 mg of 2'-O-methyluridine(Sigma chemical Co., St. Louis, Missouri) and 2.1 mCi(SP. 10Ci/mg) of Iodine-131-labeled sodium iodide in $100{\mu}l$ of water using iodogen reaction. Female Fischer 344 rats were inoculated in the thigh area with breast tumor cells(13765 NF, $10^5$ cells/rat S.C.). After 14 days, the Iodine-131-Iodomethyluridine $10{\mu}Ci$ was injected to three groups of rats(3/group). The percent of injected dose per gram of tissue weight was determined at 0.5-hours, 2-hours, 4-hours, and 24-hours respectively. Tumor bearing rats after receiving Iodine-131-Iodomethyluridine($50{\mu}Ci$ IV) were euthanized at 2 hours after injection. Autoradiography was done using freeze-dried $50{\mu}m$ coronal section. After injection of Iodine-131- Iodomethyluridine ($10{\mu}Ci$/rat, IV) in three breast tumor-bearing rats, planar scintigraphy was taken at 45 minutes, 90 minutes and 24 hours. Results : Iodine-131-Iodomethyluridine was conveniently synthesized using iodogen reaction. The biodistribution showed fast blood clearance and the tumor-to-tissue uptake ratios showed that optimal imaging time was at 2 hours postinjection. Autoradiogram and planar scintigram indicated that tumor could be well visualized. Conclusion : The findings suggest that Iodine-131-Iodomethyluridine, a new radio-iodinated nucleoside, has potential use for evaluation of active regions of tumor growth.

• Korean Journal of Environmental Biology
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• v.18 no.1
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• pp.1-20
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• 2000

There are increasing evidences of climate change in the Antarctic and Arctic Oceans, especially elevated temperature due to the continuous burning of the fossil fuels and ultraviolet B(UV-B) flux within the ozone hole. Light-dependent, temperature-sensitive, and fast-growing organisms respond to these physical and biogeochemical changes. Polar marine phytoplankton, which are pioneer endemic species and important carbon contributors in the polar waters, are therefore highly suitable biological indicators of such changes. By virtue of light requirement, the primary producers are exposed to extreme seasonal fluctuations in temperature, photosynthetically active radiation, and UV radiation. Local environmental warming and increased UV-B radiation during ozone depletion may have profound effects on the primary producers that are primary carbon producers in the polar water. Small changes in climate temperature and solar radiation may have profound effects on the activity threshold of the polar phytoplanktion. To demonstrate biological response to the environmental changes, standardized representative natural and biological parameters are needed so that replicate samples (including controls) can be taken over extended periods of time. In this paper, we review general characteristics of polar phytoplankton, their environment, environmental changes in the polar waters, the effects on the environmental changes to the polar phytoplankton, and the importance of the polar phytoplankton to understand the global environmental changes. [Biological indicators, Global environmental change, Polar phytoplankton, UV].

• Journal of the Korea Institute of Information Security & Cryptology
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• v.25 no.1
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• pp.133-146
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• 2015

Ever sophisticated e-finance fraud techniques have led to an increasing number of reported phishing incidents. Financial authorities, in response, have recommended that we enhance existing Fraud Detection Systems (FDS) of banks and other financial institutions. FDSs are systems designed to prevent e-finance accidents through real-time access and validity checks on client transactions. The effectiveness of an FDS depends largely on how fast it can analyze and detect abnormalities in large amounts of customer transaction data. In this study we detect fraudulent transaction patterns and establish detection rules through e-finance accident data analyses. Abnormalities are flagged by comparing individual client transaction patterns with client profiles, using the ruleset. We propose an effective flagging method that uses decision trees to normalize detection rules. In demonstration, we extracted customer usage patterns, customer profile informations and detection rules from the e-finance accident data of an actual domestic(Korean) bank. We then compared the results of our decision tree-normalized detection rules with the results of a sequential detection and confirmed the efficiency of our methods.