• Title/Summary/Keyword: False Positive

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Evaluation of Usefulness for Diagnosis of Lung Cancer on Integrated PET-MRI Using Decision Matrix (판정행렬을 기반한 일체형 PET-MRI의 폐암 진단 유용성 평가)

  • Kim, Jung-Soo;Yang, Hyun-Jin;Kim, Yoo-Mi;Kwon, Hyeong-Jin;Park, Chanrok
    • Journal of radiological science and technology
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    • v.44 no.6
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    • pp.635-643
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    • 2021
  • The results of empirical researches on the diagnosis of lung cancer are insufficient, so it is limited to objectively judge the clinical possibility and utilization according to the accuracy of diagnosis. Thus, this study retrospectively analyzed the lung cancer diagnostic performance of PET-MRI (Positron Emission Tomography-Magnetic Resonance Imaging) by using the decision matrix. This study selected and experimented total 165 patients who received both hematological CEA (Carcinoembryonic Antigen) test and hybrid PET-MRI (18F-FDG, 5.18 MBq/kg / Body TIM coil. VIVE-Dixon). After setting up the result of CEA (positive:>4 ㎍/ℓ. negative:<2.5㎍/ℓ) as golden data, the lung cancer was found in the image of PET-MRI, and then the SUVmax (positive:>4, negative:<1.5) was measured, and then evaluated the correlation and significance of results of relative diagnostic performance of PET-MRI compared to CEA through the statistical verification (t-test, P>0.05). Through this, the PET-MRI was analyzed as 96.29% of sensitivity, 95.23% of specificity, 3.70% of false negative rate, 4.76% of false positive rate, and 95.75% of accuracy. The false negative rate was 1.06% lower than the false positive rate. The PET-MRI that significant accuracy of diagnosis through high sensitivity and specificity, and low false negative rate and false positive rate of lung cancer, could acquire the fusion image of specialized soft tissue by combining the radio-pharmaceuticals with various sequences, so its clinical value and usefulness are regarded as latently sufficient.

THE USEFULNESS OF BONE SCAN FOR EVALUATING JAW BONE EXTENSION OF ORAL CANCER (구강암의 악골 침윤 평가에 있어서 골스캔의 효과)

  • Park, Hong-Ju;Ryu, Sun-Youl
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.26 no.6
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    • pp.658-665
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    • 2000
  • Purpose : The present study was carried out to determine the diagnostic usefulness of bone scan for evaluating jaw bone extension of oral cancer. Materials and Methods : Medical records, preoperative bone scans, computerized tomographic (CT) scans, conventional radiographs, and findings of histopathologic sections of twenty patients who had been treated for oral malignant tumors by a resection of mandible and soft tissue at Chonnam University Hospital from January, 1994 to September, 1999 were analyzed. Results : In 13 cases which showed histopathologically positive, preoperative bone scans were positive in 12 (92.3%) and false negative in 1 (7.7%). Preoperative CT scans were positive in 9 (69.2%) and false negative in 4 (30.8%) of the 13 cases. Preoperative conventional radiographs were positive in 8 (61.5%) and false negative in 5 (38.5%) of the 13 cases. In 7 cases showing negative histopathologic findings, 1 (14.3%) was in CT scans and 2 (28.6%) were false positive in preoperative conventional radiographs. Conclusion : These results suggest that bone scan is more sensitive and reliable method for evaluating jaw bone extension of oral cancer than conventional radiographs or CT scans.

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A study on improving self-inference performance through iterative retraining of false positives of deep-learning object detection in tunnels (터널 내 딥러닝 객체인식 오탐지 데이터의 반복 재학습을 통한 자가 추론 성능 향상 방법에 관한 연구)

  • Kyu Beom Lee;Hyu-Soung Shin
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.26 no.2
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    • pp.129-152
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    • 2024
  • In the application of deep learning object detection via CCTV in tunnels, a large number of false positive detections occur due to the poor environmental conditions of tunnels, such as low illumination and severe perspective effect. This problem directly impacts the reliability of the tunnel CCTV-based accident detection system reliant on object detection performance. Hence, it is necessary to reduce the number of false positive detections while also enhancing the number of true positive detections. Based on a deep learning object detection model, this paper proposes a false positive data training method that not only reduces false positives but also improves true positive detection performance through retraining of false positive data. This paper's false positive data training method is based on the following steps: initial training of a training dataset - inference of a validation dataset - correction of false positive data and dataset composition - addition to the training dataset and retraining. In this paper, experiments were conducted to verify the performance of this method. First, the optimal hyperparameters of the deep learning object detection model to be applied in this experiment were determined through previous experiments. Then, in this experiment, training image format was determined, and experiments were conducted sequentially to check the long-term performance improvement through retraining of repeated false detection datasets. As a result, in the first experiment, it was found that the inclusion of the background in the inferred image was more advantageous for object detection performance than the removal of the background excluding the object. In the second experiment, it was found that retraining by accumulating false positives from each level of retraining was more advantageous than retraining independently for each level of retraining in terms of continuous improvement of object detection performance. After retraining the false positive data with the method determined in the two experiments, the car object class showed excellent inference performance with an AP value of 0.95 or higher after the first retraining, and by the fifth retraining, the inference performance was improved by about 1.06 times compared to the initial inference. And the person object class continued to improve its inference performance as retraining progressed, and by the 18th retraining, it showed that it could self-improve its inference performance by more than 2.3 times compared to the initial inference.

The Analysis of IDS Alarms based on AOI (AOI에 기반을 둔 침입탐지시스템의 알람 분석)

  • Jung, In-Chul;Kwon, Young-S.
    • IE interfaces
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    • v.21 no.1
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    • pp.33-42
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    • 2008
  • To analyze tens of thousands of alarms triggered by the intrusion detections systems (IDS) a day has been very time-consuming, requiring human administrators to stay alert for all time. But most of the alarms triggered by the IDS prove to be the false positives. If alarms could be correctly classified into the false positive and the false negative, then we could alleviate most of the burden of human administrators and manage the IDS far more efficiently. Therefore, we present a new approach based on attribute-oriented induction (AOI) to classify alarms into the false positive and the false negative. The experimental results show the proposed approach performs very well.

Computer-Aided Detection with Automated Breast Ultrasonography for Suspicious Lesions Detected on Breast MRI

  • Kim, Sanghee;Kang, Bong Joo;Kim, Sung Hun;Lee, Jeongmin;Park, Ga Eun
    • Investigative Magnetic Resonance Imaging
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    • v.23 no.1
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    • pp.46-54
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    • 2019
  • Purpose: The aim of this study was to evaluate the diagnostic performance of a computer-aided detection (CAD) system used with automated breast ultrasonography (ABUS) for suspicious lesions detected on breast MRI, and CAD-false lesions. Materials and Methods: We included a total of 40 patients diagnosed with breast cancer who underwent ABUS (ACUSON S2000) to evaluate multiple suspicious lesions found on MRI. We used CAD ($QVCAD^{TM}$) in all the ABUS examinations. We evaluated the diagnostic accuracy of CAD and analyzed the characteristics of CAD-detected lesions and the factors underlying false-positive and false-negative cases. We also analyzed false-positive lesions with CAD on ABUS. Results: Of a total of 122 suspicious lesions detected on MRI in 40 patients, we excluded 51 daughter nodules near the main breast cancer within the same quadrant and included 71 lesions. We also analyzed 23 false-positive lesions using CAD with ABUS. The sensitivity, specificity, positive predictive value, and negative predictive value of CAD (for 94 lesions) with ABUS were 75.5%, 44.4%, 59.7%, and 62.5%, respectively. CAD facilitated the detection of 81.4% (35/43) of the invasive ductal cancer and 84.9% (28/33) of the invasive ductal cancer that showed a mass (excluding non-mass). CAD also revealed 90.3% (28/31) of the invasive ductal cancers measuring larger than 1 cm (excluding non-mass and those less than 1 cm). The mean sizes of the true-positive versus false-negative mass lesions were $2.08{\pm}0.85cm$ versus $1.6{\pm}1.28cm$ (P < 0.05). False-positive lesions included sclerosing adenosis and usual ductal hyperplasia. In a total of 23 false cases of CAD, the most common (18/23) cause was marginal or subareolar shadowing, followed by three simple cysts, a hematoma, and a skin wart. Conclusion: CAD with ABUS showed promising sensitivity for the detection of invasive ductal cancer showing masses larger than 1 cm on MRI.

Clinical Use of Cholescintigraphy in Aeute Cholecystitis: A Comparative Study with Ultrasonography (급성담낭염에서 담낭신티그라피의 임상적 이용)

  • Seo, Kwang-Hee;Chung, Hye-Kyeong;Kim, Myeong-Gon;Chung, Duck-Soo;Sung, Nak-Kwan;Kim, Ok-Dong
    • The Korean Journal of Nuclear Medicine
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    • v.27 no.1
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    • pp.81-87
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    • 1993
  • Retrospective analysis of cholescintigraphy and ultrasonography was done in 76 patients with clinically suspected acute cholecystitis to assess the relative value of the two modalities. Excluding the Patients with obstructive jaundice, the overall results of cholescintigraphy(sensitivity 100%, specificity 95%, false positive rate 5%, false negative rate 0%, accuracy 97%) are nearly identical with or rather superior to those of the ultrasonography(sensitivity 94%, specificity 100%, false positive rate 0%, false negative rate 5%, accuracy 97%). We recommend the cholescintigraphy as the initial modality in patients with clinically suspected acute cholecystitis, and ultrasonography can be used in jaundiced patients to exclude the possibility of the false positive of cholescintigraphy.

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An Analysis on the Error Probability of A Bloom Filter (블룸필터의 오류 확률에 대한 분석)

  • Kim, SungYong;Kim, JiHong
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.24 no.5
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    • pp.809-815
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    • 2014
  • As the size of the data is getting larger and larger due to improvement of the telecommunication techniques, it would be main issues to develop and process the database. The bloom filter used to lookup a particular element under the given set is very useful structure because of the space efficiency. In this paper, we introduce the error probabilities in Bloom filter. Especially, we derive the revised false positive rates of the Bloom filter using experimental method. Finally we analyze and compare the original false positive probability of the bloom filter used until now and the false decision probability proposed in this paper.

Preprocessing Technique for Lane Detection Using Image Clustering and HSV Color Model (영상 클러스터링과 HSV 컬러 모델을 이용한 차선 검출 전처리 기법)

  • Choi, Na-Rae;Choi, Sang-Il
    • Journal of Korea Multimedia Society
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    • v.20 no.2
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    • pp.144-152
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    • 2017
  • Among the technologies for implementing autonomous vehicles, advanced driver assistance system is a key technology to support driver's safe driving. In the technology using the vision sensor having a high utility, various preprocessing methods are used prior to feature extraction for lane detection. However, in the existing methods, the unnecessary lane candidates such as cars, lawns, and road separator in the road area are false positive. In addition, there are cases where the lane candidate itself can not be extracted in the area under the overpass, the lane within the dark shadow, the center lane of yellow, and weak lane. In this paper, we propose an efficient preprocessing method using k-means clustering for image division and the HSV color model. When the proposed preprocessing method is applied, the true positive region is maximally maintained during the lane detection and many false positive regions are removed.

Ultrasonographic Measurement of the Ligamentum Flavum Depth : Is It a Reliable Method to Distinguish True and False Loss of Resistance?

  • Pak, Michael Hae-Jin;Lee, Won-Hyung;Ko, Young-Kwon;So, Sang-Young;Kim, Hyun-Joong
    • The Korean Journal of Pain
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    • v.25 no.2
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    • pp.99-104
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    • 2012
  • Background: Previous studies have shown that if performed without radiographic guidance, the loss of resistance (LOR) technique can result in inaccurate needle placement in up to 30% of lumbar epidural blocks. To date, no study has shown the efficacy of measuring the depth of the posterior complex (ligamentum flavum, epidural space, and posterior dura) ultrasonographically to distinguish true and false LOR. Methods: 40 cervical epidural blocks were performed using the LOR technique and confirmed by epidurograms. Transverse ultrasound images of the C6/7 area were taken before each cervical epidural block, and the distances from the skin to the posterior complex, transverse process, and supraspinous ligament were measured on each ultrasound view. The number of LOR attempts was counted, and the depth of each LOR was measured with a standard ruler. Correlation of false and true positive LOR depth with ultrasonographically measured depth was also statistically analyzed. Results: 76.5% of all cases (26 out of 34) showed false positive LOR. Concordance correlation coefficients between the measured distances on ultrasound (skin to ligamentum flavum) and actual needle depth were 0.8285 on true LOR. Depth of the true positive LOR correlated with height and weight, with a mean of $5.64{\pm}1.06cm$, while the mean depth of the false positive LOR was $4.08{\pm}1.00cm$. Conclusions: Ultrasonographic measurement of the ligamentum flavum depth (or posterior complex) preceding cervical epidural block is beneficial in excluding false LOR and increasing success rates of cervical epidural blocks.

Clinical Value of Dividing False Positive Urine Cytology Findings into Three Categories: Atypical, Indeterminate, and Suspicious of Malignancy

  • Matsumoto, Kazumasa;Ikeda, Masaomi;Hirayama, Takahiro;Nishi, Morihiro;Fujita, Tetsuo;Hattori, Manabu;Sato, Yuichi;Ohbu, Makoto;Iwam, Masatsugu
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.5
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    • pp.2251-2255
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    • 2014
  • Background: The aim of this study was to evaluate 10 years of false positive urine cytology records, along with follow-up histologic and cytologic data, to determine the significance of suspicious urine cytology findings. Materials and Methods: We retrospectively reviewed records of urine samples harvested between January 2002 and December 2012 from voided and catheterized urine from the bladder. Among the 21,283 urine samples obtained during this period, we located 1,090 eligible false positive findings for patients being evaluated for the purpose of confirming urothelial carcinoma (UC). These findings were divided into three categories: atypical, indeterminate, and suspicious of malignancy. Results: Of the 1,090 samples classified as false positive, 444 (40.7%) were categorized as atypical, 367 (33.7%) as indeterminate, and 279 (25.6%) as suspicious of malignancy. Patients with concomitant UC accounted for 105 (23.6%) of the atypical samples, 147 (40.1%) of the indeterminate samples, and 139 (49.8%) of the suspicious of malignancy samples (p<0.0001). The rate of subsequent diagnosis of UC during a 1-year follow-up period after harvesting of a sample with false positive urine cytology initially diagnosed as benign was significantly higher in the suspicious of malignancy category than in the other categories (p<0.001). The total numbers of UCs were 150 (33.8%) for atypical samples, 213 (58.0%) for indeterminate samples, and 199 (71.3%) for samples categorized as suspicious of malignancy. Conclusions: Urine cytology remains the most specific adjunctive method for the surveillance of UC. We demonstrated the clinical value of dividing false positive urine cytology findings into three categories, and our results may help clinicians better manage patients with suspicious findings.