• Title/Summary/Keyword: Failure pattern

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The Correlation between DNA Ploidy and the Clinicohistologic Findings in Colorectal Cancer (대장직장암에서 임상조직학적 소견과 DNA ploidy와의 상관관계)

  • Lee Suk Ho;Kim Hun Jung;Kim Woo Chul;Cho Young Kap;Loh John J K;Woo Ze Hong;Hwamg Tae Sook
    • Radiation Oncology Journal
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    • v.18 no.3
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    • pp.187-193
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    • 2000
  • Purpose : DNA ploidy pattern was shown to correlate with several clinicohistologic findings in several tumors. Aim of this study was to evaluate the correlation of the clinicohistologic findings in colorectal cancer and the failure pattern in rectosigmoid cancer with DNA ploidy. Materials and Methods DNA flow cytometry using the Hedley methods on paraffin embedded specimen from 117 patients with colorectal cancers after curative resection was peformed. We tried to find the correlation between DNA ploidy and various clinicohistologic findings. And then the correlation DNA ploidy and the failure pattern in 75 patients of rectosigmoid cancer was analized. Results : Forty samples (34.2%) from tumors gave aneuploidy histogram. There was no significant difference in the frequency of DNA aneuploidy in terms of age, sex, depth of invasion, location and Dukes stage. But there was a significant correlation between DNA ploidy and the failure rates in Dukes stage B rectosigmoid cancer (P=0.048). Conclusions : These findings suggest that DNA ploidy pattern shows the correlation with the treatment failure rates in Dukes stage B rectosigmoid, but not with many other clinicohistologic findings. However,more patients will be needed to disclose these findings.

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Design of Data Retention Test Circuit for Large Capacity DRAMs (대용량 Dynamic RAM의 Data Retention 테스트 회로 설계)

  • 설병수;김대환;유영갑
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.30A no.9
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    • pp.59-70
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    • 1993
  • An efficient test method based on march test is presented to cover line leakage failures associated with bit and word lines or mega bit DRAM chips. A modified column march (Y-march) pattern is derived to improve fault coverage against the data retention failure. Time delay concept is introduced to develop a new column march test algorithm detecting various data retention failures. A built-in test circuit based on the column march pattern is designed and verified using logic simulation, confirming correct test operations.

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The Effect of Usage and Storing Conditions on John Deere 3140 Tractor Failures in Khouzestan Province, Iran

  • Afsharnia, Fatemeh;Marzban, Afshin
    • Journal of Biosystems Engineering
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    • v.42 no.2
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    • pp.75-79
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    • 2017
  • The use of tractors to carry out agricultural work has played an important role in mechanizing the agricultural sector. A repairable mechanical system (such as an agricultural tractor) is subject to deterioration or failure. In this study, a regression model was used to predict the failure rate of a John Deere 3140 tractor. The machine failure pattern was carefully studied, and key factors affecting the failure rate were identified in five regions of the Khouzestan province. Through a questionnaire, data was obtained from farm records. This data was grouped into six sub-groups, according to the annual use hours (AUH) and the manner in which the tractors were stored. Results showed that AUH and storage policies affected failure rate slightly. With an increase in the age of the tractors, the failure rate in the tractors used for 1050-2000 hours annually and stored outdoors was higher than those used for 200-1000 hours annually and stored in sheds. When the tractors were of the same age, the slope of the curve in the 200-1000 annual use hours increased gradually and then rapidly, but failure rate in the 1050-2000 annual use hours was high from the beginning, and subsequent increase in this value was almost uniform. As a result, it can be said that with an increase in the annual use hours, the failure and breakdown rate in John Deere 3140 tractors rapidly increases, but maintenance conditions only slightly affect the failure and breakdown rate.

Experimental and analytical investigation on seismic behavior of RC framed structure by pushover method

  • Sharma, Akanshu;Reddy, G.R.;Eligehausen, R.;Vaze, K.K.
    • Structural Engineering and Mechanics
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    • v.39 no.1
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    • pp.125-145
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    • 2011
  • Pushover analysis has gained significant popularity as an analytical tool for realistic determination of the inelastic behaviour of RC structures. Though significant work has been done to evaluate the demands realistically, the evaluation of capacity and realistic failure modes has taken a back seat. In order to throw light on the inelastic behaviour and capacity evaluation for the RC framed structures, a 3D Reinforced concrete frame structure was tested under monotonically increasing lateral pushover loads, in a parabolic pattern, till failure. The structure consisted of three storeys and had 2 bays along the two orthogonal directions. The structure was gradually pushed in small increments of load and the corresponding displacements were monitored continuously, leading to a pushover curve for the structure as a result of the test along with other relevant information such as strains on reinforcement bars at critical locations, failure modes etc. The major failure modes were observed as flexural failure of beams and columns, torsional failure of transverse beams and joint shear failure. The analysis of the structure was by considering all these failure modes. In order to have a comparison, the analysis was performed as three different cases. In one case, only the flexural hinges were modelled for critical locations in beams and columns; in second the torsional hinges for transverse beams were included in the analysis and in the third case, joint shear hinges were also included in the analysis. It is shown that modelling and capturing all the failure modes is practically possible and such an analysis can provide the realistic insight into the behaviour of the structure.

Risk factors for orthodontic fixed retention failure: A retrospective controlled study

  • Kaat Verschueren;Amit Arvind Rajbhoj;Giacomo Begnoni;Guy Willems;Anna Verdonck;Maria Cadenas de Llano-Perula
    • The korean journal of orthodontics
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    • v.53 no.6
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    • pp.365-373
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    • 2023
  • Objective: To investigate the potential correlation between fixed orthodontic retention failure and several patient- and treatment-related factors. Methods: Patients finishing treatment with fixed appliances between 2016 and 2017 were retrospectively included in this study. Those not showing fixed retention failure were considered as control group. Patients with fixed retention failure were considered as the experimental group. Additionally, patients with failure of fixed retainers in the period of June 2019 to March 2021 were prospectively identified and included in the experimental group. The location of the first retention failure, sex, pretreatment dental occlusion, facial characteristics, posttreatment dental occlusion, treatment approach and presence of oral habits were compared between groups before and after treatment separately by using a Fisher exact test and a Mann-Whitney U test. Results: 206 patients with fixed retention failure were included, 169 in the mandibular and 74 in the maxillary jaws. Significant correlations were observed between retention failure in the mandibular jaws and mandibular arch length discrepancy (P = 0.010), post-treatment growth pattern (P = 0.041), nail biting (P < 0.001) and abnormal tongue function (P = 0.002). Retention failure in the maxillary jaws was more frequent in patients with IPR in the mandibular jaws (P = 0.005) and abnormal tongue function (P = 0.021). Conclusions: This study suggests a correlation between fixed retention failure and parafunctional habits, such as nail biting and abnormal tongue function. Prospective studies with larger study populations could further confirm these results.

The Efficacy of Induction Chemotherapy in Stage III Non-Small Cell Lung Cancer (제 3기 비소세포 폐암에서 유도 화학 요법의 효과)

  • Cho Heung Lae;Joo Young Don;Sohn Seung Chang;Sohn Chang Hak
    • Radiation Oncology Journal
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    • v.16 no.3
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    • pp.283-289
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    • 1998
  • Purpose : This study was performed to analyze the efficacy of induction chemotherapy fellowed by radiation therapy in locally advanced non-small cell lung cancer Materials and Methods : Eighty patients with locally advanced non-small cell lung cancer treated from 1989 to 1995 at Pusan Paik hospital were analyzed retrospectively. Twenty-one patients were treated with induction chemotherapy followed by radiation therapy and Fifty-nine Patients were treated with radiation therapy alone. Chemotherapy regimen consisted of cisplatin-based combination (2 or 3 drugs). All patients were treated by Co-60 or 6 MV linear accelerators. Radiation dose ranged from 50 Gy to 80 Gy (median 64.8 Gy). We evaluated response rate, survival rate, and pattern of failure in both treatment groups. Results : Overall response rate in induction chemotherapy group and radiotherapy alone group were 48% and 45%, respectively. Of the 80 patients, 46 patients were evaluable for pattern of failure. Initial failure pattern in induction chemotherapy group was as follows: 8 (67%) at locoregional, 4 (33) in distant metastasis. Radiation alone group was 21 (71%) and 5 (29%), respectively. Results showed no difference of distant failure between induction chemotherapy group and radiation alone group. The 1 and 2 year survival rate in induction chemotherapy group were 43% and 14%, respectively and in radiotherapy alone group, 31% and 7%, respectively (p=0.135). Conclusion : In stage III non-small cell lung cancer, induction chemotherapy and radiation therapy showed increased tendency in survival with no statistical significance Induction chemotherapy seems to have no effect of decreasing distant failure and no survival advantage compared with radiotherapy alone.

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AMI Network Failure Analysis based on Graph Database (그래프 데이터베이스 기반 AMI 네트워크 장애 분석)

  • Jeong, Woo-Cheol;Jun, Moon-Seog;Choi, Do-Hyeon
    • Journal of Convergence for Information Technology
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    • v.10 no.7
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    • pp.41-48
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    • 2020
  • Recently, the spreading business of AMI (Advanced Metering Infrastructure) remote metering systems in various regions of the country has been activated, and it provides various metering functions such as two-way communication and security plan functions for power demand management. Current AMI system is difficult to analyze based on the existing RDB(Relational Database) due to the increase in the size of new internal IoT devices and networks. This study proposes a new GDB(Graph Database) based failure analysis method that utilizes existing RDB data. It analyzes the correlation of new failure patterns through accumulated data such as internal thresholds and status values. As a result of GDB-based simulation, it was confirmed that RDB can predict to a new obstacle pattern that was difficult to analyze.

A STUDY ON FAILURE STRENGTH OF THE IMPLANT PROSTHESIS LUTED WITH RESIN CEMENT BETWEEN GOLD CYLINDER AND SUPERSTRUCTURE (상부구조물과 금원주를 레진시멘트로 접착시킨 임프란트 보철물의 파절에 대한 연구)

  • Kim, Seung-Beom;Bae, Jeong-Sik
    • The Journal of Korean Academy of Prosthodontics
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    • v.34 no.3
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    • pp.438-447
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    • 1996
  • This study was performed to determine the failure strength and pattern of implant prosthesis luted with resin cement between gold cylinder and superstructure, and to evaluate the bonding strength of resin cement. To evaluate failure strength and pattern, the groups were divided into 2. Group 1 : Casted gold cylinder Group 2 : Luted with resin cement between gold cylinder ans superstructure. To evaluate effects of the bonding strength of the implant prosthesis luted with resin cement according to storage condition, the groups were divided into 3 : Group A : Stored in waste at $37^{\circ}C$ for 24 hours. Group B : 1000 cycles thermocycled between $5^{\circ}C\;and\;55^{\circ}C$ in water. Group C : Stored in water at $37^{\circ}C$ for 30 days. The results were as follows. 1. Failure was found at gold screw in all specimens of group 1 & 2. 2. The bond strength in group 1 and 2 was 189.86 and 188.14kgf. There was no statistically significant difference between group 1 and 2(P>0.05). 3. The bond strength of group A, B and C was 53.28, 45,86 and 39.29Kgf. There result suggest the advantage of an improved fit of superstructure to the abutment and a simple procedure. But there was a measurable decrease of the bond strength according to storage condition. So, Further research is necessary to evaluate of the implant prosthesis luted with resin cement between gold cylinder and superstructure.

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Study of tensile behavior of Y shape non-persistent joint using experimental test and numerical simulation

  • Sarfarazi, V.;Hajiloo, M.;Ghalam, E. Zarrin;Ebneabbasi, P.
    • Computers and Concrete
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    • v.26 no.6
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    • pp.565-576
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    • 2020
  • Experimental and discrete element methods were used to investigate the effects of angle of Y shape non-persistent joint on the tensile behaviour of joint's bridge area under brazilian test. concrete samples with diameter of 100 mm and thikness of 40 mm were prepared. Within the specimen, two Y shape non-persistent notches were provided. The large notch lengths were 6 cm, 4 cm and 2 cm. the small notch lengths were 3 cm, 2 cm and 1 cm. The angle of larger notch related to horizontal axis was 0°, 30°, 60°, 90°. Totally, 12 different configuration systems were prepared for Y shape non-persistent joints. Also, 18 models with different Y shape non-persistent notch angle and notch length were prepared in numerical model. The large notch lengths were 6 cm, 4 cm and 2 cm. the small notch lengths were 3 cm, 2 cm and 1 cm. The angle of larger notch related to horizontal axis was 0, 30, 60, 90, 120 and 150. Tensile strength of model materil was 1 MPa. The axial load was applied to the model by rate of 0.02 mm/sec. This testing showed that the failure process was mostly governed by the Y shape non-persistent joint angle and joint length. The tensile strengths of the specimens were related to the fracture pattern and failure mechanism of the discontinuities. It was shown that the tensile behaviour of discontinuities is related to the number of the induced tensile cracks which are increased by increasing the joint length and joint angle. The minimum tensile strength occurs when the angle of larger joint related to horizontal axis was 60°. Also, the maximum compressive strength occurs when the angle of larger joint related to horizontal axis was 90°. The tensile strength was decreased by increasing the notch length. The failure pattern and failure strength are similar in both methods i.e. the experimental testing and the numerical simulation methods.

The Analysis of Failure Pattern in Locally Advanced Stomach Cancer Treated with Surgery and Post-Op Chemotherapy: To Explore The Role of Post-Op Irradiation (수술과 항암요법으로 치료한 국소 진행된 위함 환자에서의 치료실패 양상분석 : 수술후 방사선 치료의 역할에 대한 연구)

  • Choi, Eun-Kyung;Chang, Hye-Sook;Suh, Cheol-Won;Lee, Kyoo-Hyung;Lee, Jung-Shin;Kim, Sang-Hee;Kim, Hae-Ryun;Kim, Myung-Hwan;Min-Young-Il;Kim, Jin-Cheon;Lee, Sung-Gyu;Park, Kun-Choon
    • Radiation Oncology Journal
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    • v.9 no.2
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    • pp.249-252
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    • 1991
  • A Retrospective study to analyze the failure pattern in locally advanced stomach cancer, treated with radical surgery and post-op chemotherapy was perfomed. Among 107 patients who underwent radical gastrectomy in Asan Medical Center between June 1989 and August 1990. there were 20 stage II(T2NO, T2N1) and 87 stage III(T3N1, T3N2) and 91 patients were eligible for study. 57 patients treated with 6 cycles of postop adjuvant chemotherapy. Among 57 patients treated with postop adjuvant chemotherapy, local failure occurred in $21\%$ and distant failure in $12\%$. Among 34 patients who were not treated with postop chemotherapy, local failure occurred in $24\%$ and distant failure in $26\%$. Among 29 failures including 13 locoregional, 9 distant metastasis and 7 locoregional and distant metastasis, 11 cases recurred in the anastomotic site, 3 in the gastric bed,7 in the regional lymph nodes and peritoneal seeding occurred in 6 cases. The true incidences of gastric bed, nodal and peritoneal failures may be higher in the longer follow-up or reoperative or autopsy series. Our data sugest that postop chemocherapy is beneficial by reducing distant failure rate. Our data suggest that postop chemocherapy is beneficial by reducing distant failure rate. Postop adjuvant locoregional radiotherapy in addition to the systemic adjuvant therapy may reduce the local failure rate and potentially benefit in at least $20\%$ of patients who developed the local failure only.

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