• Journal of Microbiology and Biotechnology
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• v.18 no.5
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• pp.997-1003
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• 2008

Viral safety is a prerequisite for manufacturing clinical antihemophilic factor VIII concentrates from human plasma. With particular regard to the hepatitis A virus (HAV), a terminal dry-heat treatment ($100^{\circ}C$ for 30 min) process, following lyophilization, was developed to improve the virus safety of a solvent/detergent-treated antihemophilic factor VIII concentrate. The loss of factor VIII activity during dry-heat treatment was of about 5%. No substantial changes were observed in the physical and biochemical characteristics of the dry-heat-treated factor VIII compared with those of the factor VIII before dry-heat treatment. The dry-heat-treated factor VIII was stable for up to 24 months at $4^{\circ}C$. The dry-heat treatment after lyophilization was an effective process for inactivating viruses. The HAV, murine encephalomyocarditis virus (EMCV), and human immunodeficiency virus (HIV) were completely inactivated to below detectable levels within 10 min of the dry-heat treatment. Bovine herpes virus (BHV) and bovine viral diarrhea virus (BVDV) were potentially sensitive to the treatment. However porcine parvovirus (PPV) was slightly resistant to the treatment. The log reduction factors achieved during lyophilization and dry-heat treatment were ${\geq}5.55$ for HAV, ${\geq}5.87$ for EMCV, ${\geq}5.15$ for HIV, 6.13 for BHV, 4.46 for BVDV, and 1.90 for PPV. These results indicate that dry-heat treatment improves the virus safety of factor VIII concentrates, without destroying the activity. Moreover, the treatment represents an effective measure for the inactivation of non-lipid-enveloped viruses, in particular HAV, which is resistant to solvent/detergent treatment.

• Journal of Korean Society of Transportation
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• v.27 no.1
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• pp.107-114
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• 2009

Human walking is essential and important mean of transportation. Pedestrian safety is recently important because accidents often happen while walking. This research is showing that Walking-environmental factors have effect on safety while walking. At first, exact 15 factors and conduct survey in the preceding research. After that, exact 4 important factors through factor analysis. At result of Multiple regression analysis, null hypothesis has proved to be true by satisfying therms which is F-value 9.211 and P-value 0.000. and come to the conclusion that walking-environmental factors influence pedestrian safety. 4 important factors can be listed by below. Pedestrian-road characteristic, landscape characteristic, commercial characteristic, walking characteristics by following influence. Especially, landscape characteristic and pedestrian-road characteristic can be vital factors.

• Journal of Fisheries and Marine Sciences Education
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• v.28 no.5
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• pp.1470-1477
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• 2016

This study has designed and evaluated the safety of watertight damper for Offshore Rigs. The watertight damper is an improved design for conventional DN 350 butterfly valve. Numerical analysis has been performed to investigate the safety factor and seat leakage of the designed 3-type disk dampers. The structure analysis results present the deformations, the equivalent stresses and the safety factor. It was confirmed that the designed disk, rib-disk and streamlined disk of watertight damper are safe enough in maximum operating pressure of 0.98MPa. The results show that the disk damper had the smallest maximum deformations and stress among 3-type disk dampers and the safety factor was 4.3. Therefore it is confirmed that the disk damper has the most excellent strength. Also linear static structural analysis was individually conducted for disk and body. The results show that the maximum disk deformation was larger than the body deformation, Therefore the disk damper is causes no seat leakage.

• The Journal of Engineering Geology
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• v.22 no.4
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• pp.375-385
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• 2012

Infiltration characteristics of cut-slope safety factors are considered for precipitation duration and intensity. Infiltration characteristics (infiltration module) and safety factor (slope module) changes of a cut-slope are analyzed under various conditions of precipitation intensity and duration, using the Soilworks program. The results indicate that the addition safety factors of the slope decreased immediately after the end of precipitation due to an increase in pore water pressure. The minimum safety factor for cut-slope infiltration analysis should be considered because of the because of the decrement of safety factors after precipitation that exceeds the decrement of safety factor during the duration of precipitation.

• Journal of Radiation Protection and Research
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• v.49 no.1
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• pp.40-49
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• 2024

Background: This study aimed to prioritize policy measures to improve radiation safety management in medical institutions using the analytic hierarchy process. Materials and Methods: It adopted three policy options-engineering, education, and enforcement-to categorize safety management measures, the so-called Harvey's 3Es. Then, the radiation safety management measures obtained from the current system and other studies were organized into action plan categories. Using the derived model, this study surveyed 33 stakeholders of radiation safety management in medical institutions and analyzed the importance of each measure. Results and Discussion: As a result, these stakeholders generally identified enforcement as the most important factor for improving the safety management system. The study also found that radiation safety officers and medical physicists perceived different measures as important, indicating clear differences in opinions among stakeholders, especially in improving quality assurance in radiation therapy. Hence, the process of coordination and consensus is likely to be critical in improving the radiation safety management system. Conclusion: Stakeholders in the medical field consider enforcement as the most critical factor in improving their safety management systems. Specifically, the most crucial among the six specific action plans was the "reinforcement of the organization and workforce for safety management," with a relative importance of 25.7%.

• Proceedings of the Safety Management and Science Conference
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• 2008.04a
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• pp.19-33
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• 2008

The study on semiconductor industrial accident in korea has been focused on frequencies of each type, employee, characteristics, cause and un-safety condition, behaviour and so on. Those attributes of semiconductor industrial accidents were usually analyzed independently, so that it was hard to provides a well-process and systematic guide lines for efficient safety management. There fore, there were a few studies based on comprehensive survey in terms of sharp-type of safe management. The questionnaire survey carried out for the workers(284) who were responsible for safety management in to center with corporate company with semiconductor industry the factor analysis showed that there were three factor of safety management. They were 1) Investment and operation and management for accident prevention, 2) Unsafe, safety management 3) General human error and behavior the industries of respondents were correlative with three group. Three Groups showed a statistically significant differences on the number of cases. Actually, the group with the larger investment and the better unsafe cause, human error a of accident prevention had a smaller cause of accident cases.

• Journal of the Korea Safety Management & Science
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• v.11 no.3
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• pp.63-71
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• 2009

Safety is totally established through not only legal regulations and system but the establishment of safety culture. As a foundation of safety culture, safety and health communication is the essential condition. Therefore, in the case of researching safety culture the communication network of a organization is a crucial factor. This study has analysed the structure of occupational safety and health communication between domestic and foreign corporations comparatively by the statistical analysis. The occupational safety and health communication is composed of four sub-dimensions: general communication in working site, using safety information communication, communication with the board of directors, and communication with labor union. The nationality of corporations influences the safety communication significantly except for communication with labor union. Consequently it is possible to infer that the nationality of corporations is a significant factor for safety communication network.

• Safety and Health at Work
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• v.7 no.4
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• pp.326-330
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• 2016

Background: The Nordic Safety Climate Questionnaire-50 (NOSACQ-50) was developed by a team of Nordic occupational safety researchers based on safety climate and psychological theories. The aim of this study was to develop and validate the Persian version of NOSACQ-50 and assess the score of safety climate on a group of workers in a steel company in Iran. Methods: The Persian version of NOSACQ-50 was distributed among 661 employees of a steel company in Qazvin Province (Iran). Exploratory factor analysis (EFA) and confirmatory factor analysis were used to determine the dimensions of the questionnaire. The reliability of the questionnaire was assessed using Cronbach ${\alpha}$ coefficient. Pearson correlation test was applied to investigate the correlation between different dimensions. Results: The results of EFA showed that the Persian version of NOSACQ-50 consisted of six dimensions. The Cronbach ${\alpha}$ coefficient of the questionnaire was 0.94. The mean score of safety climate in all dimensions was 2.89 (standard deviation 0.60). Conclusion: The Persian version of NOSACQ-50 had a satisfactory validity for measuring safety climate in the studied Iranian population.

• Korean Journal of Agricultural Science
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• v.45 no.4
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• pp.889-903
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• 2018

The purposes of this study were to classify consumer types and to analyze purchase behavior depending on food safety attitudes related to the Fukushima nuclear accident. Based on the consumer survey data, factor analysis and cluster analysis were done to classify consumer types. Applying factor analysis, six factors with a total variance of 73.4% were extracted from 22 basic variables. The 6 factors were termed 'anxiety from ingesting agricultural and fishery products after the nuclear accident', 'importance of food safety when purchasing food', 'reduced rate of purchases of agricultural and fishery products after the accident', 'importance of food prices', 'socio-demographic characteristics' and 'family composition'. Using cluster analysis, consumers were classified into 5 types using the factor scores of 6 factors. The main results are as follows. For every consumer type, the anxiety about imported agricultural and fishery products was higher than that for domestic products after the nuclear accident. The food safety attitudes of consumers were mainly formed by the socio-demographic characteristics. Consumer types with high-education and high-income responded flexibly to the food safety concerning the accident; especially, the consumer type with a high-income and kids under 19 responded very reasonably to the accident. However, consumer types with a low-income and aged over 50 or less than 30 years were the least responsive to the accident, mainly due to financial restrictions. Thus, we suggest some food safety strategies and policy implications based on consumer type for food safety after the accident.

• Journal of the Korea Safety Management & Science
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• v.15 no.4
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• pp.209-216
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• 2013

By means of the model competition, this research analyzed the factor of patient management, the factor of policy support, and the factor of medical treatment system. Concretely, the factor of policy support forms a positive effects on the factor of medical treatment system. Practically, well-established healthcare policy provide and facilitate the effective medical treatment system. of the hospital. And, in the effective medical treatment system, hospitals try to develop the patient management of the chronic disease. From the empirical research, this paper concluded that the factor of medical treatment system. mediated by the factor of policy support. Also, the factor of medical treatment system promotes the development of patient management in the chronic disease.