• 제목/요약/키워드: Factor H

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건강한 성인에서 피부 산도와 영양소 섭취 및 식사패턴과의 상관성 연구 (A Study on the Relationship of Skin Surface pH with Nutrient Intake or Dietary Pattern in Healthy Adults)

  • 강혜진;김건표;조윤희
    • 한국식품영양학회지
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    • 제30권1호
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    • pp.9-18
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    • 2017
  • As an indicator of skin health, acidified skin surface pH ranging from 5 to 7 is crucial for maintaining skin barrier. In this study, we evaluated the relationship between skin pH and dietary pattern (DP) as well as nutrient or food intake in 48 healthy middle aged adults. Skin pH was measured in the skin surface of the inner arm, and blood lipid profile was analyzed. Dietary intake data were obtained using 1 day 24 hour recall method, and DP was extracted using factor analysis. Results revealed that skin pH ranged from 5.15 to 6.88 in all subjects. There was no significant difference in skin pH between males and females. When subjects were grouped by tertile of skin pH, the food intake of fruit, and the nutrient intake of omega 6 fatty acid, potassium, vitamin A, vitamin C, ${\beta}$-carotene, and riboflavin in the first tertile group with skin pH ranging from 5.15 to 5.68 were significantly higher than in the third tertile group with skin pH ranging from 6.26 to 6.88. There was no difference in blood lipid profile between the first and the third tertile group. Among 5 DP extracted by factor analysis, DP5 characterized by a high intake of nuts and fruits as well as a low intake of beverages and alcohol was inversely correlated with skin pH after adjusting for gender and age. DP5 was positively correlated with nutrient intake of carbohydrate, fiber, potassium, iron, vitamin A, vitamin C, ${\beta}$-carotene, thiamine, and riboflavin but negatively correlated with sodium after adjusting for gender, age, smoking, and energy intake. Therefore, acidified skin pH could be maintained by these DP and nutrients.

실도로 주행에서 PEMS를 이용한 소형 경유 상용차의 가스 상 유해대기오염물질 배출계수 연구 (Emission Factor of Hazardous Air Pollutants in Gas-phase from Light Commersial Vehicle using PEMS on Real-road Driving)

  • 임지혜;한상우;김정;장영기;전문수;황성철;김정화;정성운;김정수;한진석
    • 한국대기환경학회지
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    • 제34권2호
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    • pp.191-206
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    • 2018
  • In this study, the HAPs(Harzard Air Pollutants) emission factor level of Starex and Grand Carnival was tested using PEMS (Portable Emissions Measurement System) on real road driving. As a result of RDE (Real Driving Emission test), the overall vehicle speed pattern showed similar characteristics. The real-road driving test at constant speed revealed emission factor is inversely proportional relationship to constant speed. Results of accelerating with speed limit on the real-road were shown as followings; Uran (less than 45 km/h)>Rural (<45 km/h, less than 80 km/h)>Motorway (>80 km/h). Moreover, the sudden acceleration and deceleration in driving at high speed was the increasing factor to the HAPs emission factor. This tendency is considered to be influenced by the operating environment on real roads.

Studies on the Development of Novel 305 day Adjustment Factors for Production Traits in Dairy Cattle

  • Cho, K.H.;Na, S.H.;Cho, J.H.;Lee, J.H.;Lee, K.J.
    • Asian-Australasian Journal of Animal Sciences
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    • 제17권12호
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    • pp.1689-1694
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    • 2004
  • This study was conducted to develop a novel adjustment factors for 305 days using 138,103 lactation records and 1,770,764 daily records, which were based on environmental circumstances such as herd year, season, age at calving, dry period and lactating stages. The present study showed that the change of persistency of cows at the first parity from total lactacting characteristics was slowly processed, while it was rapidly changed in cows at the second parity stage. Particularly, there was an outstanding difference between the first and second parity cows. Milk yield and composition increased as the age at calving was increased. In addition, milk yield and composition were higher at the first parity on fall compared with others, and those were higher at the more than second parity on fall and winter compared with other parity stages and seasons. The cow of dry group was included into lactating records of more than second parity stage. The data indicated that optimal results arose from 45-70 days of dry period. Milk yield was decreased when dry period was longer or shorter than 45-70 days. The lactating days were divided into 17, 28 and 38 stages to compare the multiplicative correction factors. The factor was effective at 28 stages on the first parity. The total correlation coefficients were 0.93832, 0.95058 and 0.95076 at the present correction factor, 17 stage and 28 stage, respectively. At second parity, the factor was higher in dry group 1 and 3 at 17 stage, and it was higher in dry group 2 at 28 stage compared with others. Therefore, the present study showed that the percent squared bias (PSB), which was calculated from the novel correction factor, was better than previously used correction factors. Also, the present study indicated that the bias of the novel correction factor was improved, and this factor could be more accurate compared with others.

Bacillus subtilis ATCC6633이 Bacillus subtilis cx1의 박테리오신 생산에 미치는 유도효과 (Enhancement of Bacteriocin Production by Bacillus subtilis cx1 in the Presence of Bacillus subtilis ATCC6633)

  • 장미;장해춘
    • 한국미생물·생명공학회지
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    • 제34권3호
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    • pp.221-227
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    • 2006
  • 박테리오신 BSCX1은 Bacillus subtilis cx1에 의해 생산되는 항균성 peptide이다. B. subtilis cx1의 박테리오신(BSCX1)은 Bacilius subtilis ATCC6633, Listeria monocytogenes KCTC3569를 포함한 그람양성균과 Salmonella typhi ATCC19430, Escherichia coli ATCC25922와 같은 그람음성균에 대해서도 비교적 넓은 항균활성 범위를 가진다. 박테리오신 생산균주인 B. subtilis cx1과 그것의 감수성 균주인 B. subtilis ATCC6633을 공동 배양한 결과, 박테리오신 BSCX1의 생산이 증가됨을 확인할 수 있다. 이 결과는 박테리오신 생산균주 B. subtilis cx1의 성장 배지내에 박테리오신 감수성 균주가 존재함이 BSCX1 생산을 촉진시키는 것을 의미한다. 감수성 균주의 박테리오신 유도 작용을 확인하였으므로 유도물질이 감수성 균주의 어느 위치에 존재하는지 밝히기 위해 B. subtilis ATCC6633을 분획하여 실험한 결과 세포내 분획과 세포파쇄물에 모두 유도물질이 존재함을 확인하였다. BSCX1 유도물질의 유도활성은 pH 2.5에서 pH 9.5에 걸쳐 전 구간에서 유지되었으며, $50^{\circ}C$이상에서는 3시간 이내에 불활성화 되었다. 유도물질에 단백분해효소인 proteinase K를 처리한 결과 유도활성이 사라져 단백질성 물질임을 알 수 있었다.

천곡동굴의 수질환경 장기 모니터링 (A Long-term Monitoring of Water Quality at Chongok Cave)

  • 전병희
    • 한국지반환경공학회 논문집
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    • 제14권9호
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    • pp.13-19
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    • 2013
  • 천곡동굴은 동해시에 자리잡고 있는 석회암동굴로서 많은 돌리네를 가지고 있어 관광적 가치와 교육적 가치가 매우 높다. 하지만 천곡동굴은 시가지에 위치하고 있어 접근이 용이한 반면 하수의 유입 등에 의해 환경적 영향을 받을 가능성이 매우 크다. 본 연구에서는 천곡동굴의 수질환경을 장기 모니터링하여 생태계의 영향을 조사하고, 향후 장기 모니터링을 위한 인자를 선정하였다. 그 결과 천곡동굴 내 지하수의 수온은 $14^{\circ}C$, 용존 산소량은 10mg/L 이상, pH는 7-8의 범위에서 안정되게 유지되고 있어, 수생태계에 부정적 영향을 주는 수질적 요소는 없는 것으로 판단되었다. 관람객의 안전을 확보하기 위한 강우기준으로서 일강우로서 60mm/d가 적절하며 향후 장기 모니터링을 위해서 전기전도도를 주된 인자로 이용하고 pH와 탁도를 보조적으로 활용하는 것이 적절하며, 계절적 변화 등을 ORP를 이용하여 모니터링하는 것이 적절하다고 판단되었다.

Hydrogen sulfide restores cardioprotective effects of remote ischemic preconditioning in aged rats via HIF-1α/Nrf2 signaling pathway

  • Wang, Haixia;Shi, Xin;Cheng, Longlong;Han, Jie;Mu, Jianjun
    • The Korean Journal of Physiology and Pharmacology
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    • 제25권3호
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    • pp.239-249
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    • 2021
  • The present study explored the therapeutic potential of hydrogen sulfide (H2S) in restoring aging-induced loss of cardioprotective effect of remote ischemic preconditioning (RIPC) along with the involvement of signaling pathways. The left hind limb was subjected to four short cycles of ischemia and reperfusion (IR) in young and aged male rats to induce RIPC. The hearts were subjected to IR injury on the Langendorff apparatus after 24 h of RIPC. The measurement of lactate dehydrogenase, creatine kinase and cardiac troponin served to assess the myocardial injury. The levels of H2S, cystathionine β-synthase (CBS), cystathionine γ-lyase (CSE), nuclear factor erythroid 2-related factor 2 (Nrf2), and hypoxia-inducible factor (HIF-1α) were also measured. There was a decrease in cardioprotection in RIPC-subjected old rats in comparison to young rats along with a reduction in the myocardial levels of H2S, CBS, CSE, HIF-1α, and nuclear: cytoplasmic Nrf2 ratio. Supplementation with sodium hydrogen sulfide (NaHS, an H2S donor) and l-cysteine (H2S precursor) restored the cardioprotective actions of RIPC in old hearts. It increased the levels of H2S, HIF-1α, and Nrf2 ratio without affecting CBS and CSE. YC-1 (HIF-1α antagonist) abolished the effects of NaHS and l-cysteine in RIPC-subjected old rats by decreasing the Nrf2 ratio and HIF-1α levels, without altering H2S. The late phase of cardioprotection of RIPC involves an increase in the activity of H2S biosynthetic enzymes, which increases the levels of H2S to upregulate HIF-1α and Nrf2. H2S has the potential to restore aging-induced loss of cardioprotective effects of RIPC by upregulating HIF-1α/Nrf2 signaling.

다변량분석법을 이용한 금강 유역의 수질오염특성 연구 (Evaluation of the Geum River by Multivariate Analysis: Principal Component Analysis and Factor Analysis)

  • 김미아;이재관;조경덕
    • 한국물환경학회지
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    • 제23권1호
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    • pp.161-168
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    • 2007
  • The main aim of this work is focus on the Geum river water quality evaluation of pollution data obtained by monitoring measurement during the period 2001-2005. The complex data matrix 19 (entire monitoring stations)*13 (parameters), 60 (month)*13 (parameters) and 20 (season)*13 (parameters) were treated with different multivariate techniques such as factor analysis/principal component analysis (FA/PCA). FA/PCA identified two factor (19*13) classified pollutant Loading factor (BOD, COD, pH, Cond, T-N, T-P, $NH_3$-N, $NO_3$-N, $PO_4$-P, Chl-a), seasonal factor (water temp, SS) and three Factor (60*13, 20*13) classified pollutant Loading factor (BOD, COD, Cond, T-N, T-P, $NH_3$-N, $NO_3$-N, $PO_4$-P), seasonal factor (water temp, SS) and metabolic factor (Chl-a, pH). Loadings of pollutant factor is potent influence main factor in the Geum river which is explained by loadings of pollutant factor at whole sampling stations (71.16%), month (52.75%) and season (56.57%) of main water quality stations. Result of this study is that pollutant loading factor is affected at Gongju 1, 2, Buyeo 1, 2, Gangkyeong, Yeongi stations by entire stations and entire month (Gongju 1, Cheongwon stations), April, May, July and August (buyeo 1) by month. Also the pollutant Loading factor is season gives an influence in winter (Gongju 1, buyeo 1) from main sampling stations, but Cheongwon characteristic is non-seasonal influenced. This study presents necessity and usefulness of multivariate statistic techniques for evaluation and interpretation of large complex data set with a view to get better information data effective management of water sources.

ABSTRACT RELATIVE FOURIER TRANSFORMS OVER CANONICAL HOMOGENEOUS SPACES OF SEMI-DIRECT PRODUCT GROUPS WITH ABELIAN NORMAL FACTOR

  • Farashahi, Arash Ghaani
    • 대한수학회지
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    • 제54권1호
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    • pp.117-139
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    • 2017
  • This paper presents a systematic study for theoretical aspects of a unified approach to the abstract relative Fourier transforms over canonical homogeneous spaces of semi-direct product groups with Abelian normal factor. Let H be a locally compact group, K be a locally compact Abelian (LCA) group, and ${\theta}:H{\rightarrow}Aut(K)$ be a continuous homomorphism. Let $G_{\theta}=H{\ltimes}_{\theta}K$ be the semi-direct product of H and K with respect to ${\theta}$ and $G_{\theta}/H$ be the canonical homogeneous space (left coset space) of $G_{\theta}$. We introduce the notions of relative dual homogeneous space and also abstract relative Fourier transform over $G_{\theta}/H$. Then we study theoretical properties of this approach.

Pine Forest Soil Characteristics and Major Soil Impact Factors for Natural Regeneration

  • Kim, Min-Suk;Kim, Yong-Suk;Min, Hyun-Gi;Kim, Jeong-Gyu;Koo, Namin
    • 한국토양비료학회지
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    • 제50권3호
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    • pp.179-186
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    • 2017
  • This study was conducted to identify characteristics of domestic pine forest soils and to elucidate major soil influencing factors for natural regeneration. We analyzed the physico-chemical characteristics of the soil samples collected from 23 pine forests and confirmed the similar results with the forest soil characteristics. Soil pH, organic matter content, total nitrogen, exchangeable Ca, silt content, and exchangeable Al were selected as the major soil factors among the exposed soils through 10 days of pine seedlings exposure and cultivation experiments and statistical analysis. Multiple regression analysis showed that soil pH had a positive effect on specific root length (SRL) of red pine seedlings and exchangeable Al was a significant factor affecting negative change in SRL. Taken together, the reduction of exchangeable Al by soil pH adjustment would be helpful for natural regeneration by restoring the forest and improving the fine root and root integrity of pine seedlings. Therefore, soil pH and exchangeable Al could be recommended as a major soil factor to be carefully considered in the monitoring and management of soil in pine forests that need to be renewed in the future.