• 대한화장품학회지
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• 제42권3호
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• pp.279-284
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• 2016

연구에서는 수염에 대한 면도력을 향상시킬 수 있는 화장료 제형 개발을 위하여 대면용 화장료에서 사용가능한 우레아 및 여러 항산화제의 수염 강도 약화 효과를 연구하였다. 실제 모발 강도 약화 효과는 우레아 농도에 의존적인 성향을 보였으며, 모발 면적 증가율 역시 농도에 의존적인 것으로 나타나 우레아 농도에 따라 모발의 수화 정도가 달라지며 이것이 강도 약화에 영향을 주는 것을 확인할 수 있었다. 항산화제는 종류에 따라 소량으로도 뛰어난 강도 감소 효과를 보이며, 이는 모발에 다량 존재하는 시스틴 결합을 환원시키기 때문으로 해석된다. 마지막으로 대면용으로서의 적합성 판단을 위해 우레아 및 항산화제의 in vitro 안전성 테스트를 진행하였다. 안전성 테스트 결과 우레아는 대면용으로 사용하기 적합한 정도로 나타났으며, 항산화제 중에서는 글루타치온이 적합한 것으로 나타났다. 위 결과들을 통해 피부 자극이 적고 모발 강도 약화 효과가 뛰어나 면도용 제품에 적용하기 적합한 원료는 우레아 및 글루타치온임을 알 수 있었다.

• 대한소아치과학회지
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• 제23권3호
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• pp.688-696
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• 1996

Garre's osteomyelitis is a unique form of osteomyelitis characterized rediographically by localized thickening of the periosteum and deposition of laminated subperiosteal bone. The most common inciting factor is a mandibular infection in permanent first molar with necrotic pulp. This disease occurs primarily in children and to date in all instances it has occured only in mandible. It usually results in hard swelling over the jaws, producing facial asymmetry with little or no pain. The overlying skin is normal but can occasionally be inflammed mostly when pain is present. Palpation reveals a usually smooth, bone-hard lesion which feel like an inherent part of the mandible. Unlike other forms of osteomyelitis, there is no marked increase in fever, white bloods cell count, sedimentation rate or alkaline phosphatase value. The treatment of Garre's osteomyelitis usually consist of elimination of the sourses of infection, i.e., either extration of an offending infected teeth or root canal therapy. This treatment almost always results in resolution of the Garre's osteomyelitis. Resistant cases have involved secondary surgery, i.e., decortication and sequestrectomy. This report presents three cases of Garre's osteomyelitis resolved by endodontic treatment. Cliniqtl examination revealed swelling on the face with no tenderness. Periapical radiograph showed deep caries lesion extending into pulp chamber and periapical radiolucency. Occlusal radiograph showed an enlargement of bone and stretching the periosteum. A clinical diagnosis of the Garre's osteomyelitis was made. Endodontic treatment was accomplished with conventional method and restored facial symmetry. Long-term check-ups are necessary to evaluate the results of endodontic treatment.

• Journal of Dental Anesthesia and Pain Medicine
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• 제20권5호
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• pp.313-323
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• 2020

Background: Previous studies have investigated the effects of dexamethasone injections into the pterygomandibular space and compared them to those of controls; however, the effects of dexamethasone injections before and after lower third molar surgery on postoperative complications have not been studied. This research investigated the postoperative sequelae of dexamethasone injections before and after surgery into the pterygomandibular space. The aim of this study was to evaluate the effects of preoperative and postoperative injections of 4 mg of dexamethasone into the pterygomandibular space on postoperative pain, facial swelling, and the restriction of mouth opening following lower third molar surgical removal. Methods: Twenty-seven participants with bilateral symmetrical lower impacted third molars were included in this study. Each participant was randomly allocated to one of two groups. Group A received injections of 1 ml dexamethasone (4 mg/mL) and 1 mL placebo into the pterygomandibular space before and after surgery, respectively. Group B received the same doses of placebo before surgery and dexamethasone after surgery. Results: A significant restriction of mouth opening on the second postoperative day was observed in both groups. Nonetheless, the postoperative restriction of mouth opening, facial swelling, postoperative pain, and analgesic consumption after lower third molar surgical removal were not significantly different in the two groups. Conclusions: Regardless of the time of administration, dexamethasone injections into the pterygomandibular space resulted in satisfactory control of the postoperative sequelae of the mandibular third molar surgical removal.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제18권4호
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• pp.607-614
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• 1996

중앙안면골 골절 환자에서 비골 골절과 동반되는 경우가 많으며, 주로 안면골 골절의 정복시 비골도 동시에 정복하지만 여러 가지의 원인에 의하여 이차 비성형술을 시행하여야 하는 경우가 많다. 그러므로 중앙안면골 골절 환자의 초진시 비골 골절에 대한 정확한 진단과 정확한 비골 골절의 정복 그리고 일차 비골 골절의 정복후 이의 적절한 유지와 고정이 중요하지만 이차 비성형술의 가능성에 대비하여야 하며, 일차 비골 골절의 정복시 대칭적인 정복을 시행함으로서 비교적 간단하게 이차 비성형술을 시행할 수 있으리라 생각되었다. 또한 중앙안면골 골절환자에서는 비부의 연조직이나 연골의 이차변형에 의하여 이차 비성형술을 시행할수도 있으므로 일차 수술후 주의깊은 관찰이 요구된다. 이러한 이차 비성형술에는 자가이식재 및 Silicone이나 $Medpore^{(R)}$등이 이용될 수 있으며, 특히 인공이식재의 경우 공여부의 정확한 형성과 적절한 고정이 필수적이며 향후 이러한 인공이식재의 안정성에 대한 더 많은 연구가 이루어져야 할것으로 사료된다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제16권2호
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• pp.202-207
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• 1994

본원에서는 안면부 손상후 발생한 피하기종과 기종격이 있는 두 환자를 치험하였다. 다른부위 손산 없이 단독으로 안면부 손상후 발생한 피하기종과 기종격은 예후가 좋고 자연치유가 잘되지만 심각한 합병증 및 후유증을 방지하기 위하여 세심한 관찰 및 보존적 처치가 요구된다. 이에 저자들은 증상, 진단. 해부학적구조, 발생가전, 합병증, 치료양식등의 문헌고찰과 더불어 치험 증례를 보고 하는 바이다.

• 대한치과의사협회지
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• 제52권7호
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• pp.425-431
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• 2014

Objectives : The purpose of our study was to evaluate penicillin as a still drug of choice for severe endodontic infection, by analyzing the antimicrobial susceptibilities from endodontic infections with swelling to figure out appropriate antibiotics as empirical treatment. Materials and methods : This study involved 18 patients who attended for emergency treatment because of facial or periapical swelling associated with root canal infections. Identification and antimicrobial susceptibility test of each pathogen were performed by Vitek2 Systems (bioM$\acute{e}$rieux, Marcy l'Etoile, France). Results : The most frequent bacteria was Streptococcus spp.(77%), and the resistance against penicillin was 35% in overall patients, followed by clindamycin and erythromycin (17%), which was much higher than previous studies. Conclusions : In our study, the higher resistance made penicillin alone not to be chosen as the first antibiotic drug for severe endodontic infections. Combinations with other drug, penicillin with wider spectrum of activity, or changing to other antibiotics was considered while remembering the increased risk of resistant microorganism.

• Imaging Science in Dentistry
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• 제30권3호
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• pp.217-222
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• 2000

A 31-year-old male with the complaint of severe limitation of mouth opening was referred to our department of Chonbuk National University Hospital. The physical status of the patient was hyposthenic. Extraoral examination showed no condylar movement of the both temporomandibular joints, no pain, no facial swelling or paresthesia. Intraoral examination showed several cervical caries on the upper anterior teeth, and gingival swelling on the whole dentition. Transcranial view showed no condylar movement, and narrowing of joint spaces. Chest P-A view showed straightening of thoracic, lumbar spine, and squaring of vertebrae of the same spines. Conventional lateral radiograph of cervical spine showed calcification of the intervertebral ligament. Computed tomograph showed extensive bone formation between temporal bone and the condylar head at both sides. Laboratory findings showed positive reaction on HLA-B27 histocompatibility antigen and increased level of IgA, IgG, ESR. Based on the clinical, radiographic, and the laboratary findings, final diagnosis was made as bony ankylosis of the both temporomandibular joints secondary to ankylosing spondylitis.

• 한국임상수의학회지
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• 제20권3호
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• pp.399-402
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• 2003

A female unknown aged Yorkshire terrier, weighing 3.5 kg with nasal discharge, left facial swelling and severe inflammation was referred to Veterinary Medical Teaching Hospital, Seoul National University. Radiographic findings were lytic change and soft tissue swelling of left zygomatic process and increased radiopacity of nasal cavity. In computed tomography, turbinate bone destruction was observed as well as lytic change of left zygomatic process and left maxilla indicating aggressive lesion. Then 3-dimensional reconstruction was also performed. Biopsy of tissue mass revealed it as squamous cell carcinoma. For this patient, euthanasia was performed guarded prognosis. Generally, tumors of the nasal cavity in dogs account for approximately 1 % to 2% of all neoplasms. The prevalence of these tumors increased with age and exposure to the ultraviolet. About two thirds of all nasal tumors are malignant tumors such as squamous cell carcinoma and adenocarcinoma. As these tumors of nasal cavity are locally invasive, and external beam radiotherapy is the current treatment of choice. Unfortunately, diagnosis of these tumors often occurs late in the course of disease, resulting in a poor prognosis for outcome in many patients. It is considered that computed tomography could be used as an aid modality for the exact evaluation of extend and degree of bone lysis of nasal cavity and metastasis.

• Journal of Oral Medicine and Pain
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• 제45권2호
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• pp.44-47
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• 2020

The case of pseudo-aneurysm of internal maxillary artery (IMA) in oral and maxillofacial region is known to be very rare. The etiology of this case was regarded as IMA injury by radiofrequency ablation (RFA) and such incidence was not reported previously. One case of false aneurysm in the IMA was referred from local dental clinic to our department. Left facial swelling was observed with severe trismus immediately after radiofrequency procedure for masseteric nerve block in local dental clinic. Despite of medication and surgical intervention, the swelling did not subside and there was massive bleeding and pulsation on one of the follow ups. The traumatic vascular disorder was suspected and finally diagnosed with angiography and treated by embolization procedure. RFA targeting masseteric nerve or trigeminal ganglion may cause traumatic injury to adjacent anatomic structures such as IMA, resulting in pseudo-aneurysm. Clinicians must be aware of potential damages of RFA. Angiography enables the solid diagnosis for pseudo-aneurysm, and selective embolization can be optimum treatment method.

• 한국임상수의학회지
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• 제24권3호
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• pp.449-452
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• 2007

A 2 year-old intact male Shih-tzu dog was presented with a history of snakebite on the left upper lip. He was depressed and had swelling, erythema and pain around the left muzzle. Both mandibular lymph nodes were swollen. Fang marks were not clear, but there were scratch wounds and prolonged bleeding. Hemogram revealed neither thrombocytopenia nor echinocytosis. Increased CK value in serum chemistry and myoglobinuria in urine analysis meant muscle injury. With careful monitoring, fluid, corticosteroid, antihistamine and antibiotics were administered. After the application of ice pack and suction, local symptoms changed for the worse. However, any other systemic disorders were not identified. After 5 days, the facial swelling had resolved completely.