• 동의생리병리학회지
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• 제35권6호
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• pp.267-273
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• 2021

Mibyeong (sub-health) is a concept that represents the sub-health in traditional East Asian medicine. Assuming that the nose sizes and shapes are related to respiratory function, in this study, we hypothesized that the nose size and shape features are related to the self-rated health (SRH) level and self-rated Mibyeong severity, and aimed to assess this relationship using a fully automated image analysis system. The nose size features were evaluated from the frontal and profile face images of 810 participants. The nose size features consisted of five length features, one area feature, and one volume feature. The level of SRH and the Mibyeong severity were determined using a questionnaire. The normalized nasal height was negatively associated with the self-rated health score (SRHS) (partial ρ = -0.125, p = 3.53E-04) and the Mibyeong score (MBS) (partial ρ = -.172, p = 9.38E-07), even after adjustment for sex, age, and body mass index. The normalized nasal volume (ρ = -.105, p = 0.003), the normalized nasal tip protrusion length (ρ = -.087, p = 0.014), and the normalized nares width (ρ = -.086, p = .015) showed significant correlation with the SRHS. The normalized nasal area (ρ = -.118, p = 0.001), the normalized nasal volume (ρ = -.107, p = .002) showed significant correlation with the MBS. The wider, longer, and larger the nose, the lower the SRHS and MBS, indicating that health status can be estimated based on the size and shape features of the nose.

• 대한두개안면성형외과학회지
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• 제22권6호
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• pp.310-318
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• 2021

Background: Transcutaneous lower eyelid approaches are associated with a risk of postoperative scarring depending on the distance between the incision line and the lower eyelid margin. The lower eyelid crease of Caucasians corresponds to a ridge-shaped fold in young Asians. However, this relationship has not been sufficiently evaluated in the latter. The authors, therefore, investigated the location of the scar and the lower eyelid crease or ridge to find the optimal location for the incision line. Methods: This study included 60 out of 139 patients who underwent inferior orbital wall reconstruction through a lower eyelid skin incision between July 2019 and June 2020. According to the location of the scar, the patients were classified into three groups: group A (≥ 2 mm above the lower eyelid crease or ridge), group B (within the lower eyelid crease or ridge to 2 mm above the lower eyelid crease or ridge), and group C (within the lower eyelid crease or ridge to 2 mm below the lower eyelid crease or ridge). At 6 or 12 months after surgery, the Patient and Observer Scar Assessment Scale (POSAS) score was obtained, the distance between the lower eyelid margin and the scar (DMS) and the distance between the margins of the peripheral pupil and the lower eyelid (DMPE) were measured, and the occurrence of ectropion was evaluated. Results: Group B had the lowest POSAS score (A: 22.7 ± 8.0, B: 20.9 ± 2.4, C: 32.5 ± 4.1, p< 0.001). Linear regression analysis showed that the DMS was positively correlated with the POSAS score (p< 0.001) and that the risk of DMPE widening increased as the DMS decreased (p= 0.029). None of the patients had ectropion. Conclusion: When using the transcutaneous approach for inferior orbital wall reconstruction, the optimal incision site is within the lower eyelid crease or ridge to 2 mm above the lower eyelid crease or ridge.

• Journal of Genetic Medicine
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• 제18권2호
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• pp.110-116
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• 2021

Microdeletions of chromosome 22q11.2 are one of the most common microdeletions occurring in humans, and is known to be associated with a wide range of highly variable features. These deletions occur within a cluster of low copy repeats (LCRs) in 22q11.2, referred to as LCR22 A-H. DiGeorge (DGS)/velocardiofacial syndrome is the most prevalent form of a 22q11.2 deletions, caused by mainly proximal deletions between LCR22 A and D. As deletions of distal portion to the DGS deleted regions has been extensively studied, the recurrent distal 22q11.2 microdeletions distinct from DGS has been suggested as several clinical entities according to the various in size and position of the deletions on LCRs. We report a case of long-term follow-up of a female diagnosed with a 22q11.2 distal deletion syndrome, identified a deletion of 1.9 Mb at 22q11.21q11.23 (chr22: 21,798,906-23,653,963) using single nucleotide polymorphism array. This region was categorized as distal deletion type of 22q11.2, involving LCR22 D-F. She was born as a preterm, low birth weight to healthy non-consanguineous Korean parents. She showed developmental delay, growth retardation, dysmorphic facial features, and mild skeletal deformities. The patient underwent a growth hormone administration due to growth impairment without catch-up growth. While a height gain was noted, she had become overweight and was subsequently diagnosed with pre-diabetes. Our case could help broaden the genetic and clinical spectrum of 22q11.2 distal deletions.

• Imaging Science in Dentistry
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• 제52권1호
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• pp.43-51
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• 2022

Purpose: The aim of this study was to evaluate the reliability of the Vectra M3 (3D Imaging System; Canfield Scientific, Parsippany, NJ, USA) in detecting chin asymmetry, and to assess whether the automatic markerless tracking function is reliable compared to manually plotting landmarks. Materials and Methods: Twenty subjects (18 females and 2 males) with a mean age of 42.5±10.5 years were included. Three-dimensional image acquisition was carried out on all subjects with simulated chin deviation in 4 stages (1-4 mm). The images were analyzed by 2 independent observers through manually plotting landmarks and by Vectra software auto-tracking mode. Repeated-measures analysis of variance and the Tukey post-hoc test were performed to evaluate the differences in mean measurements between the 2 operators and the software for measuring chin deviation in 4 stages. The intraclass correlation coefficient (ICC) was calculated to estimate the intra- and inter-examiner reliability. Results: No significant difference was found between the accuracy of manually plotting landmarks between observers 1 and 2 and the auto-tracking mode (P=0.783 and P=0.999, respectively). The mean difference in detecting the degree of deviation according to the stage was <0.5 mm for all landmarks. Conclusion: The auto-tracking mode could be considered as reliable as manually plotted landmarks in detecting small chin deviations with the Vectra^® M3. The effect on the soft tissue when constructing a known dental movement yielded a small overestimation of the soft tissue movement compared to the dental movement (mean value<0.5 mm), which can be considered clinically non-significant.

• 대한두개안면성형외과학회지
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• 제23권5호
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• pp.205-210
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• 2022

Background: Nasal bone fractures are the most common type of facial bone fracture, but are under-studied in adults above 65 years of age. Therefore, we investigated the epidemiology and patterns of nasal bone fractures among older adults in comparison to different age groups. Methods: This retrospective study included 2,321 nasal bone fracture patients who underwent surgery at our hospital from January 2010 to December 2017. The patients were classified by age as preschoolers, school-age children, young and middle-aged adults, and the elderly. We performed pairwise comparisons between elderly patients and each other age group in terms of sex, cause of injury, and fracture type. Results: The 2,321 nasal bone fracture patients included 76 elderly patients (50 men [65.8%] and 26 women [34.2%]). In these patients, the two most common injury causes were falling or slipping down (n= 39; 51.3%) and road traffic accidents (n= 19; 25.0%). According to the Stranc and Robertson classification, the most common force vector was lateral, and plane 2 fractures with lateral forces predominated. Conclusion: The elderly showed similar patterns of nasal bone fractures to those observed in young and middle-aged adults, but significant differences from preschoolers (in the injury vector and plane of fracture) and from school-age children (in the sex ratio and plane of fracture). However, elderly patients presented significantly different epidemiological characteristics compared to the other three groups. Therefore, it is necessary to improve the quality of life of the elderly and prepare for the upcoming super-aged society by taking steps to reduce the incidence and severity of fractures. Possible options for doing so include strengthening individual-level safety factors and expanding the social safety net for the elderly.

• 대한소아치과학회지
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• 제49권2호
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• pp.234-240
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• 2022

Floating Harbor 증후군 (FHS)은 드문 유전질환이다. 본 증례는 FHS를 가진 환아에 대해 소개하였다. 환아는 독특한 얼굴 형태, 저성장된 상악과 전돌된 하악을 동반한 심한 골격적 3급 부정교합, 결손치, 왜소치, 상악 치아의 이소맹출을 보였다. 쌍둥이 여동생은 하악 전돌을 동반한 경미한 골격성 3급 부정교합은 보였으나 결손치와 왜소치는 보이지 않았다. 높은 구개궁, 넓은 난형의 하악궁에 비해 좁은 V형의 상악궁, 역의 관계의 상하악 구치간 폭경으로 인한 구치부 반대교합이 환자의 모델 분석을 통해 확인되었다. 이러한 특성은 쌍둥이에서는 나타나지 않았다. 행동면에서 환아는 경미한 정신지체로 인해 치과 치료 중 낮은 협조도를 보였다.

• International Journal of Computer Science & Network Security
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• 제22권10호
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• pp.97-106
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• 2022

Objective. Nanotechnology is spreading among all areas of life, from everyday devices to medicine. The concept of nanotechnology argues that not only can new physical and chemical properties of materials be discovered, but also the new potential of nanostructures when reduced to the nanoscale. The growing interest in the application of nanomaterials in dentistry contributes to the proliferation of the range of nanomaterials used by specialists. The purpose of this review of information sources was to analyze the prospects for the use of nanomaterials in dentistry. Methods. We used the bibliographic semantic method of research, for which we analyzed electronic databases of primary literature sources Scopus, Web of Science, Research Gate, PubMed, MDPI, and MedLine. English-language scientific articles published after 2017 were taken into consideration. Results. According to the results of a search study among modern information primary sources, nanotechnology improves the preventive properties of oral care products, improves the structural-mechanical and aesthetic properties of composite mixtures for dentistry, overcomes the problems of the clinical application of dental implants. Despite the prospects of nanotechnology applications in medicine in general and dentistry in particular, the existing economic and technological problems require a thorough solution for further implementation of nanostructures. Scientific novelty. For the first time, the analysis of modern trends in the application of nanotechnology in dentistry is carried out and the peculiarities of materials are highlighted, the problems and prospects of nanostructures implementation in modern dental implantology are given, physical, chemical, mechanical, and antibacterial properties of nanomaterials are evaluated. The effect of nanomaterials on the microbial adhesion of the tooth or implant surface is described. Practical significance. The presented publication can become a scientific basis for the solution of urgent problems hindering the introduction of nanotechnology into dental practice. Conclusions. Thus, the use of nanostructures opens up great opportunities for the treatment of a wide range of diseases, not only of dental nature but also in medicine in general.

• 한국의류산업학회지
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• 제24권6호
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• pp.782-788
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• 2022

Our research participants were composed of health teachers exhausted by the COVID-19 pandemic. This study analyzed the attitudes towards image-making through utilizing the job training at Gwangju Metropolitan Office of Education on August 2022, where our study was able to obtain and analyze 30 elementary, middle, and high school health teachers who participated. Image making is defined as playing a role in increasing self-esteem through outward appearances such as facial expressions and posture, personal color, makeup, tone, hairstyling, and fashion and impacting individuals inwardly to increase self-confidence. Therefore, there is a positive impact in providing an image-making program that considers the occupational characteristics of a health teacher. It had the effect of stress relief and aided in building a healthier self-image among the participants. The results our study showed the following results. First, all participants had various concerns regarding their appearance and deemed that image-making was necessary, yet they needed to be more informed regarding the specific methods of doing so. Secondly, participants were mainly focused on purchasing makeup products for image making. Although participants showed interest in a personal color diagnosis, there needed to be more support in approaching the subject as the diagnosis was necessary from an expert. Third, participants stated that image-making should occur for their middle-aged selves when experienced in the field. Participants believed that they would be more concerned with how others viewed them after gaining expertise. Hence, this study found that the occupational characteristics of health teachers greatly benefitted from image-making programs oriented to their careers and would also show an increase in job satisfaction.

• 대한두개안면성형외과학회지
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• 제23권6호
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• pp.256-261
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• 2022

Background: Treating panfacial fractures (PFFs) can be extremely difficult even for experienced surgeons. Although several authors have attempted to systemize the surgical approach, performing surgery by applying a unidirectional sequence is much more difficult in practice. The purpose of this study was to review the literature on PFF surgery sequence and to understand how different surgical specialists-plastic reconstructive surgery (PRS) and oral maxillofacial surgery (OMS)-chose sequence and review PFFs fixation sequence in clinical cases. Methods: The PubMed and Google Scholar databases were scoured for publications published up until May 2020. Data extracted from the studies using standard templates included fracture part, fixation sequence, originating specialist, and the countries. Bibliographic details like author and year of publication were also extracted. Also, we reviewed the data for PFFs patients in the Trauma Registry System of Dankook University Hospital from 2011 to 2021. Results: In total, 240 articles were identified. This study comprised 22 studies after screening and full-text analysis. Sixteen studies (12 OMS specialists and 4 PRS specialists) used a "bottom-top" approach, whereas three studies (1 OMS specialist and 2 PRS specialists) used a "top-bottom" method. However, three studies (only OMS specialists) reported on both sequences. In our hospital, there were a total of 124 patients with PFF who were treated during 2011 to 2021; 64 (51.6%) were in upper-middle parts, 52 (41.9%) were in mid-lower parts, and eight (6.5%) were in three parts. Conclusion: Bottom-top sequencing was mainly used in OMS specialists, and top-bottom sequencing was used at a similar rate by two specialists in literature review. In our experience, however, it was hard to consistently implement unidirectional sequence suggested by a literature review. We realigned the reliable and stable buttresses first with tailoring individually for each patient, rather than proceeding in the unidirectional sequence like bottom-top or top-bottom.

• 대한두개안면성형외과학회지
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• 제24권2호
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• pp.59-65
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• 2023

Background: Fibrous dysplasia (FD) is a localized bone disorder in which fibro-osseous tissue replaces the normal bone structure. Patients with craniofacial FD often present with gradual swelling, deformity, and compromised vision or hearing. We previously introduced "the core extirpation method," a novel surgical technique that is minimally invasive like traditional bone shaving but has longer-lasting effects. This study presents the long-term outcomes of our core extirpation method. Methods: We conducted a retrospective analysis of patients who underwent core extirpation for FD of the zygomaticomaxillary region from 2012 through 2021. Computed tomography (CT) scans were performed 6 to 12 months before the operation, immediately before and after the operation, and during follow-up visits. We performed all operations using the upper gingivobuccal approach, and we extirpated the core of the lesion while preserving the cortical structures of the zygoma and the maxilla to maintain symmetrical facial contour. Results: In 12 patients with lesions in the growth phase, anteroposterior/mediolateral (AP/ML) length discrepancies and the volume increased between preoperative and immediate postoperative CT scans. All patients' immediate postoperative AP/ML discrepancies were stable up to 12-17 months postoperatively. Postoperative volume showed continuous lesion growth; the median volume growth rate was 0.61 cc per month. Conclusion: In this article, we present our experiences managing FD using the minimally invasive core extirpation technique, which entails small expected blood loss and can be performed as day surgery. It provides similar cosmetic outcomes as traditional bone shaving but with longer-lasting results. Although there are some limitations with the study's retrospective nature and small sample size, our 4-year follow-up results show promising results of the core extirpation method in well-indicated patients.