• Journal of Life Science
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• v.17 no.4 s.84
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• pp.587-592
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• 2007

Manipulation of the mouse genome by activating or inactivating the gene has contributed to the understanding of the function of the gene in the subset of cells during embryonic development or postnatal period of life. Most of all, gene targeting, which largely depends on the availability of mouse embryonic stem (ES) cells, is the milestone of development of animal models for human disease. Recombinase-mediated genome modification (Cre-LoxP and Flp-Frt etc) and the ligand-dependent regulation system, more accurate and elaborate manipulation tools, have been successfully developed and applied to dissect the mechanisms governing complex biological processes and to understand the role of protein in temporal-and spatial aspects of development. As technologies concerning refined manipulation of mouse genome are developed, they are expected to open new opportunities to better understand the diverse in vivo functions of genes.

• Journal of Korean Physical Therapy Science
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• v.13 no.4
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• pp.7-16
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• 2006

The purpose of this study was designed to find out the effectiveness of vertebral segment instability, muscle fatigue response on lumbar spine after apply lumbosacral stabilization exercise program to 4 patients with chronic low back pain and for 12 weeks. In this study, the lumbar spine motion with blind by MedX test machine and the difference of instability to lumbar vertebra segments in flexion, extension test of standing position and spinal load test(Matthiass Test) by Spinal Mouse. The stabilization exercise program was applied 2 times a week for 12 weeks in hospital and 2 times a day for 20 minutes at home. The results of the present study were as follows: 1. Instability test of lumbar vertebra segment is 2 type differential angle test between vertebrae segment and loading test of spine(matthiass) by Spinal Mouse. It appeared to improve stability of segments in sagittal plane after program. So lumbar spine curve increased lordosis toward anterior and was improved of the lumbar spine flexibility in flexion and extension. Specially, in matthiass test, ( - ) value was increased between lumbar vertebra segment when was the load on spine. And so stability improved after program. 2. Fatigue response test(FRT) results, in male, was raised muscle fatigue rate during increase weight, on the other hand female appeared lower than male. As a results, lumbosacral stabilization exercise was aided to improvement of lumbar spine vertebra segments stabilization. Spine instability patients will have a risk when in lifting a load or working with slight flexion posture during the daily of living life and it is probably to increase recurrence rate. Thus, not only lumbar extension muscle strength but also stability of vertebra segments in lumbar spine may be very important.

• Journal of the Korea Convergence Society
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• v.11 no.5
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• pp.253-260
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• 2020

This study was performed to evaluate the effects of Visual feed-back ankle training combined with Ankle joint Functional electrical stimulation on balance, gait ability on patient with Chronic Stroke. A total of 22 chronic stroke patients were divided into VFAF Group, CON group. Each group performed 60 minutes a day 5 times a week for 8 weeks. VFAF group revealed significant differences in balance and gait ability as compared to the CON groups(p<.05). The exercises were conducted for 60 min per day, five, per week for eight weeks. Balance and gait ability were examined at 0 week and after 8 weeks of intervention. Our results showed that VFAF was more effective on balance ability and gait ability in chronic stroke patients. We suggest that this study will be able to be used as an clinical intervention data for recovering balance and gait ability in chronic stroke patients.

• Journal of Korean Physical Therapy Science
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• v.16 no.4
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• pp.67-74
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• 2009

Background: This study had been carried out with 20 elderly subjects as its object for about one month from November 3, 2008 to December 14, 2008 in order to observe the effect of Underwater Treadmill on the elderly's walking and balance ability. Methods: Subjects were assigned either experimental group (n=10) or the control group (n=10), experimental group received Underwater Treadmill program (30 min per course, 3days a week for 6weeks). Subjects were assessed for muscle power (Nicolas Manual Muscle Test), balance (Functional Reach Test), gait ability (Time Up and Go, 10M walking test) before experiments and after experiments. Results: The results of this study were as follows; 1. After underwater treadmill exercise, the change of isometric contraction indicated a beneficial increase on lower extremity muscle power of experimental group and functional test of balance function; FRT, TUG indicated beneficial difference between groups. 2. beneficial difference between groups in walking speed of hourly index change of walking function. 3. between muscle power and balance, gait ability, we could find out there's high correlation ship between lower extremity muscle power increasing and balance and gait ability of the elderly. Conclusion: Aerobic exercise using underwater treadmill effects on muscle power strengthening of the elderly, and because of this, increase of lower extremity muscle power is very helpful not only to improvement of balance ability, but also to improvement of gait ability, so it will be used as a physical therapy program on clinic and used as an exercise program for protecting the elderly from falling down very well.

• Journal of the Korean Wood Science and Technology
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• v.41 no.6
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• pp.559-565
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• 2013

This study evaluated the ability of white and brown rot fungi to decompose fire retardant-treated wood by measuring mass loss. Anti efficacy of FRT against sapstain and mold fungi was evaluated. Wood was treated with liquid sodium silicate and boric acid, ammonium borate, di-ammonium phosphate. Retardant treated wood was then subjected to fungal decay resistance tests performed according to KS standard method using a brown-rot fungus, Fomitopsis palustris and white rot fungus Trametes versicolor. Aspergillus niger, Penicillium funiculosum, Rhizopus nigricans, Aureobasidium pullulans, Tricoderma virede fungi were used anti-sapstain and mold test. Boron and phosphorus chemicals used in this study increased the resistance of fire retardant treated wood against both fungal attack. Anti mold and sapstain efficacy of the fire retardant treated wood was excellent but there were difference depend on mold. After the liquid sodium silicate treatment, the second chemical treatment process could lead chemical fixation into wood, which effects decay resistance.

• Physical Therapy Rehabilitation Science
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• v.3 no.1
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• pp.55-62
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• 2014

Objective: To study the effects of gait training with additional weight and gait training with non-additional weight on balance ability and gait ability in patients with chronic stroke through comparative analysis. Design: Randomized controlled trials. Methods: The subjects were divided randomly into two groups: additional weight group (AWG, n=12), and non-additional weight group (NAWG, n=10). Both groups received general physical therapy for 30 min in 1 session, 5 sessions per week during 6 months. The AWG practiced gait training with additional weight of 0.1 and 0.5 kg for 20 min a day, 3 days per week for 6 months and the NAWG practiced gait training with non-additional weight for 20 min a day, 3 days per week for 6 months. Patients in both groups were instructed to walk as fast as they could along a 35 m long track (straight for 20 m and curved for 15 m). Patients walked with their hemiplegic side on the inside of the track while a physical therapist followed along to instruct patients to maintain a straight posture. Balance ability was tested with the Functional Reach Test, the Timed Up and Go test, and the Berg Balance Scale, and gait ability was tested with GAITRite. The results of balance and gait ability were analyzed before and after interventions. Results: A significant increase in FRT, TUG, BBS was seen in both groups after intervention (p<0.05). A significant increase in gait ability was seen in the AWG after intervention (p<0.05). For balance and gait ability, the results from the AWG was significantly improved compared with the NAWG (p<0.05). Conclusions: Gait training with additional weight improves balance ability and gait ability in stroke patients, this gait training method is effective and suitable for stroke patients to increase the ability of functional performance.

• PNF and Movement
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• v.15 no.1
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• pp.77-84
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• 2017

Purpose: This study aimed to investigate the effect of visual feedback training-for gradual weight shift in sit-to-stand training-on the balance and walking abilities of chronic hemiplegia patients. Methods: Twenty patients with chronic hemiplegia volunteered to participate in this study. The experimental group received visual feedback for gradual weight shift in the sit-to-stand training, while the contrast group followed the standard process for the sit-to-stand training. The evaluation of the balance and walking ability was conducted with the functional reach test (FRT), Berg balance scale (BBS), five time sit-to-stand (FTSTS) test, timed up and go (TUG) test, 10 m walk test (10MWT), balancia, activities-specific balance confidence (ABC) scale, and falls efficacy scale (FES). Results: In the results before and after intervention, there was a significant difference in TUG, 10MWT, ABC, and FES in the visual feedback training group (p < 0.05). In the control group, there was a significant difference in the 10MWT and ABC (p < 0.05). Also, in the evaluation of the postural fluctuations, the control group data showed a significant increase in Covar. The visual feedback group showed a significant difference in the W average. Conclusion: The visual feedback training group showed some improvement in terms balance and walking ability and on the ABC scale and FES. Therefore, if the diagonal progressive weight bearing exercise is combined with the various patterns and basic principles of PNF, it may be a more efficient intervention method.

• The Journal of Korean Society for Neurotherapy
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• v.22 no.3
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• pp.19-23
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• 2018

Purpose The purpose of this study was to investigate the change of balance ability by performing closed chain exercise on stable support surface and unstable support surface in twenties. Methods This study randomly selected 15 students in the closed chain exercise group on the stable support side and 15 on the closed chain exercise group on the unstable support side. Balance ability was measured before and after the start of exercise and static balance was measured by OLT(One Leg Standing Test) and FRT (Functional Reach Test). Result The changes of the function reach test of the closed chain movement according to the ground type were significant in the unstable and stable support surfaces and the change of function reach test after the intervention in the two groups was significantly improved compared with the closed chain movement respectively. The one leg standing test changes of the closed chain movement according to the ground type showed significant results on the unstable and stable support surfaces, but there was no significant difference in the one leg standing test changes after intervention between the two groups. Conclusion The effect of closed chain training on ground type is unstable. The change of function reach test and one leg standing test of the closed chain exercise group on the stable support surface resulted in significant changes after exercise, but there was a significant difference in the balance ability of function reach test change after intervention between the groups.

• Journal of Korean Physical Therapy Science
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• v.25 no.3
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• pp.53-60
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• 2018

Purpose : The purpose of this study is to examine the Effect of Lunge Exercise on the Balance of Stable and Unstable Supporting surface. Method : The experimenter was a healthy twenties male and female. The period was two weeks, divided into a stable group and a unstable group. Setting the holding time 4 sec 3 sets of 10 times using the Stable and Unstable Supporting Surfaces. The break time was set at one minute for each set. Balance cushions were used for unstable supporting surfaces. Results : After Lunge Exercise, Both groups had an impact on improving their ability to balance. Conclusion : There has not been much change in the ability to balance the stable and Unstable Supporting Surfaces. However, considering surface conditions, the pre and post exercise comparisons had an effect on improving the ability to balance.

• Journal of Korean Physical Therapy Science
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• v.29 no.4
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• pp.17-26
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• 2022

Background: The aim of this study was to investigate the effects of heel raising with kinesio taping (HRKT) on triceps surae muscle activity and balance in 20s adults. Design: Two groups pre-post randomized controlled design. Methods: The total of 40 subjects were randomly divided in the HRKT group (experimental group, n=21) and heel raising with sham kinesio taping (control group, n=19). Both groups receive heel raising with kinesio taping and sham kinesio taping for 20 minutes a day, five day per week, for four weeks. Measurement were performed before training and 4 weeks after training. The triceps surae muscle activity was measured using the EMG. A functional reach test (FRT) was used to evaluate balance ability. The independent t-test was conducted to compare exercise methods depending on the taping effect on each group. Results: The both group showed significant differences in muscle activity of lower extremity and functional reach test in the pre-post intervention comparison (p<0.05). The experimental group showed significantly more improvement in triceps surae muscle activity and functional reach test compared to the control group(p<0.05). Conclusion: We confirmed that the effects of heel-raising with kinesio taping group on triceps surae muscle activity and balance ability in 20s adults. The result suggest that heel raising with kinesio taping for 20s adults should be further studied and considered.