• The Journal of Korean Medicine
• /
• v.32 no.1
• /
• pp.141-150
• /
• 2011

Objectives: The aim of this study was to elucidate the antioxidant effect of solvent fractions of Angelica gigas root. Methods: The ethanol extract of Angelica gigas root was suspended in water and then partitioned with dichloromethane (MC Fr.), ethyl acetate (EA Fr.) and butanol (BuOH Fr.), sequentially. The antioxidant activities of solvent fractions of Angelica gigas root were evaluated for radical scavenging activity against stable free radicals (2,2-diphenyl-1-picrylhydrazyl) DPPH, hydrogen peroxide and superoxide anion radicals. In addition the antioxidant activities of solvent fractions of Angelica gigas root against peroxyl radicals, hydroxyl radicals and peroxynitrites were determined by the total oxy-radical scavenging capacity (TOSC) assay. Results: Among the solvent fractions of MC Fr., EA Fr., and BuOH Fr., BuOH Fr. was found to have stronger antioxidant activity with $IC_{50}$ values of 59.72, 14.36, 30.96 and $44.75\;{\mu}g/m{\ell}$ on the DPPH radical, nitrite, superoxide anion and hydrogen peroxide, respectively, than BHA used as a positive control. Moreover, specific TOSC values(564.8, 276.4 and 405.5 TOSC/mM) of BuOH fr. against peroxyl radicals, hydroxyl radical and peroxynitrite were 4 times higher than GSH (136.5, 67.4 102.6 TOSC/mM) used as a positive control. Conclusions: These results suggest that the BuOH fr. of Angelica gigas root has a high antioxidant activity and can be useful to develop functional food against oxidative stress conditions.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.28 no.5
• /
• pp.1029-1033
• /
• 1999

Seven fractions were separated by silica gel chromatography from the diethyl ether souble portion of the methanolic extract of the cultured hoelen(Poria cocos Wolf). Three fractions were separated from the Fr.II and Fr.IV by rechromatography, respectively. The most active fraction, Fr.II 3 and Fr.IV 3, were separated to 2 and 4 fractions by preparative HPLC. On the result of antimicrobial test, triterpenoids fractions showed weaker effect than benzoic acid but Fr.II 3 1, Fr.II 3 2 had an excellent antimi crobial activity. Triterpenoids fraction of hoelen(Poria cocos Wolf) showed a high inhibition activity on the growth of lung cancer, ovary cancer, skin cancer, central nerve cancer and rectum cancer cell, especially the activity of Fr.II 3 1 and Fr.II 3 2 was the highest.

• Journal of the Korean Mathematical Society
• /
• v.44 no.4
• /
• pp.845-854
• /
• 2007

In this paper we investigate relationships between closure-type and convergence-type properties of hyperspaces over a space X and covering properties of X.

• Asian-Australasian Journal of Animal Sciences
• /
• v.22 no.3
• /
• pp.388-395
• /
• 2009

The current study was conducted to investigate the effect of early feed restriction (FR, 8 to 14 d of age) on growth performance and immune function in broiler chickens. Birds were fed corresponding diets from 3 to 35 d of age, which consisted of three phases: starter (3 to 7 d of age), FR (8 to 14 d of age) and re-alimentation (15 to 35 d of age) phases. During the FR period, each group of birds was fed the basal diet ad libitum (CON), 85% (EN85) and 70% (EN70) of lower calorie diet ad libitum (qualitative FR), and 85% (FI85) and 70% (FI70) of voluntary intake on a daily basis (quantitative FR). As a result, there was no statistical difference in weight gain, feed intake and feed conversion ratio between the CON and quantitative or qualitative FR groups during the entire (3 to 35 d) periods. In particular, the EN85 group resulted in a significant (p<0.05) increase in weight gain compared with the EN70, FI85 and FI70 groups. Plasma total protein and albumin at 14 d of age (during FR) were significantly (p<0.05) lower in the quantitative and qualitative FR groups, but these parameters at 35 d of age (after re-alimentation) were higher (p<0.05) in the EN85 and EN70 groups than in the CON group. Plasma IgG level was unaffected by dietary FR procedure. In cytokines, there was no significant difference in the expression of lymphocytic IL-4 and IFN-${\gamma}$ at 14 d of age between the FR and the CON groups, whereas lymphocytic IL-6 and iNOS expression were significantly (p<0.05) lower in FI85 and FI70 groups. Moreover, lymphocytic iNOS was also significantly (p<0.05) lower in birds fed qualitative and quantitative diets compared with those fed ad libitum. In the thymus, IL-4 expression was higher (p<0.05) in FI85 and FI70 groups, whereas IL-6 expression was lower (p<0.05) in the FI85 and FI70 groups than in the CON group. Thymic iNOS was significantly (p<0.05) lower in birds fed qualitatively and quantitatively restricted diets compared with those fed ad libitum. At 35 d of age, there was no difference in the expression of IL-4, IL-6 and IFN-${\gamma}$ of lymphocytes and thymus between the FR and CON groups. In conclusion, 85% of quantitative and qualitative FR would have a beneficial effect on the expression of some cytokines including IL-4 and iNOS without change in growth performance of birds.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.26 no.3_4
• /
• pp.473-484
• /
• 2002

The physical characteristics of silk and wool fabrics dyed with OFS-FR and SM-FR were examined and color difference and colorfastness of these fabrics were analyzed. The results are as follows; 1. The thickness, density and weight of both dyed fabrics were increased than those of undyed fabrics independently of dyeing materials and mordants. 2. Air permeability of all the silk samples increased than that of undyed silk, on the other hand, air permeability of most of wool samples decreased than that of undyed wool. 3. Thermal insulation values of silk samples were not consistent with dyeing conditions, but those of wool samples increased than those of undyed fabrics regardless of dyeing materials and mordants. 4. Color difference was clear between OFS-FR and SM-FR dyed fabrics. The colors dyed with OFS-FR-Al and OFS-FR-chitos an showed violet, those dyed with SM-FR displayed yellowish, in addition to in case of wool, dyed with OFS-FR-Cu the color was greenish yellow, in case of silk dyed with SM-FR-Cu that was yellowish red. 5. Sense of silk fabrics by sensory-test was soft and smooth. Feeling of colors in silk fabrics was wick, warm and slightly brilliant. In case wool, sense of dyed fabrics was slightly soft and slightly rough. Feeling of colors in wool fabrics was warm but not elegant. Therefore the result of sensory-test in silk might be better than that of in wool. 6. Colorfastness to dry cleaning and perspirations was good, but that to washing and sunlight was not fine.

• Korean Journal of Food Science and Technology
• /
• v.41 no.1
• /
• pp.87-92
• /
• 2009

The antioxidant properties and protective effects of Inula britannica on ${H_2}{O_2}$-induced SH-SY5Y neuroblastoma cell damage were investigated. A series of solvent fractions, including hexane(Fr.H), petroleum ether, chloroform, ethyl acetate(Fr.EA), and water fraction(Fr.W), were prepared from the 70% methanol extracts of Inula britannica. Fr.W had the highest total contents of phenolics and flavonoids, followed by Fr.EA. The antioxidant properties of the fractions were also evaluated by analyzing their scavenging activities on 1,1-diphenyl-2-picrylhydrazyl(DPPH) radicals, 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals, and nitric oxide. Fr.W showed the strongest activities in all assays. The concentrations of Fr.W that resulted in 50% reductions of the DPPH and ABTS radicals were 20.7 ${\mu}g$/mL and 39.4 ${\mu}g$/mL, respectively. Fr.W showed the weakest cytotoxic activities on the SH-SY5Y cells, whereas it effectively protected ${H_2}{O_2}$-induced cell death, increasing cell survival by 35.0-77.0% at a concentration range of 62.5-250 ${\mu}g$/mL. In this range, Fr.W also significantly decreased intracellular ROS levels by 34-39%. Overall, the antioxidant properties of Inula britannica can contribute to rescuring neuronal cells from oxidative stress-induced cell injury.

• Korean Journal of Metals and Materials
• /
• v.47 no.1
• /
• pp.26-31
• /
• 2009

The effects of $Ar/O_2$ ion-beam pre-treatment conditions on the interfacial adhesion energy of sputterdeposited Cu thin film to FR-4 substrate were systematically investigated in order to understand the interfacial bonding mechanism for practical application to advanced chip-in-substrate package systems. Measured peel strength increases from $45.8{\pm}5.7g/mm$ to $61.3{\pm}2.4g/mm$ by $Ar/O_2$ ion-beam pre-treatment with anode voltage of 64 V. Interfacial bonding mechanism between sputter-deposited Cu film and FR-4 substrate seems to be dominated by chemical bonding effect rather than mechanical interlocking effect. It is found that chemical bonding intensity between carbon and oxygen at FR-4 surface increases due to $Ar/O_2$ ion-beam pretreatment, which seems to be related to the strong adhesion energy between sputter-deposited Cu film and FR-4 substrate.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.17 no.4
• /
• pp.1182-1199
• /
• 2023

Fractional repetition (FR) codes can achieve exact uncoded repair for multiple failed nodes, with lower computational complexity and bandwidth overhead, and effectively improve repair performance in distributed storage systems (DSS). The actual distributed storage system is dynamic, that is, the parameters such as node storage overhead and number of storage nodes will change randomly and dynamically. Considering that traditional FR codes cannot be flexibly applied to dynamic distributed storage systems, a new construction scheme of adaptive-and-resolvable FR codes based on hypergraph coloring is proposed in this paper. Specifically, the linear uniform regular hypergraph can be constructed based on the heuristic algorithm of hypergraph coloring proposed in this paper. Then edges and vertices in hypergraph correspond to nodes and coded packets of FR codes respectively, further, FR codes is constructed. According to hypergraph coloring, the FR codes can achieve rapid repair for multiple failed nodes. Further, FR codes based on hypergraph coloring can be generalized to heterogeneous distributed storage systems. Compared with Reed-Solomon (RS) codes, simple regenerating codes (SRC) and locally repairable codes (LRC), adaptive-and-resolvable FR codes have significant advantages over repair locality, repair bandwidth overhead, computational complexity and time overhead during repairing failed nodes.

• Advances in concrete construction
• /
• v.4 no.1
• /
• pp.49-69
• /
• 2016

This work investigates the mechanical properties of conventional concrete (CC) and self compacting concrete (SCC) using fine rubber and silpozz were accompanied by a comparative study between conventional rubberized concrete (CRC) and self compacting rubberized concrete (SCRC). Fine rubber (FR) from scrap tires has replaced the fine aggregate (FA) and Silpozz has been used as a replacement of cement at the proportions of 5, 10 and 15%. Silpozz as a partial replacement of cement in addition of superplasticiser (SP) increases the strength of concrete. Fresh concrete properties such as slump test, compaction factor test for CRC, whereas for SCRC slump flow, $T_{500}$, V-funnel, L-box, U-box, J-ring tests were conducted along with the hardened properties tests like compressive, split tensile and flexural strength test at 7, 28 and 90 days of curing. The durability and microstructural behavior for both CRC and SCRC were investigated. FR used in the present study is 4.75 mm passing with fineness modulus 4.74.M30 grade concrete is used with a mix proportion of 1:1.44:2.91 and w/c ratio as 0.43. The results indicate that as FR quantity increases, workability of both CRC and SCRC decreases. The results also show that the replacement of natural fine aggregate (NFA) with FR particles decreases the compressive strength with the increase of flexural strength observed upto 5% replacement of FR. Also replacement of cement with silpozz resulted enhancement of strength in SCRC.

• Journal of the Korean Applied Science and Technology
• /
• v.34 no.2
• /
• pp.271-279
• /
• 2017

This study evaluated antimicrobial efficacy and antioxidant effect of fraction isolated from Coptis Radix and confirmed its possibility as a cosmetic material. The extracts of isolated from Coptis Radix conducted an antimicrobial activity against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Candida albicans by disc diffusion method and measure clear zone. As a result, it was confirmed that antimicrobial activity against S. aureus and candida. A was observed in all samples except Fr 1. The activity of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and The activity of 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) cation radical scavenging were determined by antioxidant assay according to the concentrations (50, 125, 250) ${\mu}g/mL$ of extracts of isolated from Coptis Radix. As a result, DPPH radical scavenging activity of Fr 1, 2, 3, 4 at $250{\mu}g/mL$ was 11.4%, 30.3%, 42.0% and 53.1%, respectively and $ABTS^+$ radical scavenging activity was 28.6%, 96.2%, 98.6% and 97.1% at the same concentration, respectively. Fr. 3 and 4 showed higher radical scavenging activity than the positive the control group BHT at the same concentration. In the WST assay results of measuring the cytotoxicity of Coptis Radix, except for Fr. 4, Fr. 1, 2 and 3 did not show toxicity. As a result, the fractions isolated from Coptis Radix can be regarded as a cosmetic material having antimicrobial activity and antioxidant ability.