• Title/Summary/Keyword: FLS

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Shoot and Fruit Characteristics of Peach 'Cheonhong' Tree affected by Various Fruiting Levels (착과 수준에 따른 복숭아 '천홍'의 신초 발생 및 과실 특성)

  • Kim, Ho Cheol
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.2
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    • pp.339-343
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    • 2021
  • This study was conducted to compare the shoot development and fruit characteristics on fruit bearing branch (FBB) according to the fruiting level (FLs: FL-Low, -Middle, -High) of peach 'Cheonhong'. The number of shoots per FBB according to the FLs were most distributed in 1-2 (42%) of FL-Low, 1 (47%) of FL-Middle and 1 (42%) of FL-High. And fruit weight and soulable solide content were 210-270g (50%) and 10-12Brix (44%), 180-240g (60%) and 10-12Brix (59%), 180-240g (60%) and 11-13Brix (48%), respectively. In addition, only FL-High showed a linear regression correlation between fruit weight and number of shoots. And a linear regression equation of y=0.0126x+8.1857 (R2=0.1964, P≤0.01) is shown between the souble solid content (y) and the fruit weight (x).

RUNX1 Ameliorates Rheumatoid Arthritis Progression through Epigenetic Inhibition of LRRC15

  • Hao Ding;Xiaoliang Mei;Lintao Li;Peng Fang;Ting Guo;Jianning Zhao
    • Molecules and Cells
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    • v.46 no.4
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    • pp.231-244
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    • 2023
  • Leucine-rich repeat containing 15 (LRRC15) has been identified as a contributing factor for cartilage damage in osteoarthritis; however, its involvement in rheumatoid arthritis (RA) and the underlying mechanisms have not been well characterized. The purpose of this study was to explore the function of LRRC15 in RA-associated fibroblast-like synoviocytes (RA-FLS) and in mice with collagen-induced arthritis (CIA) and to dissect the epigenetic mechanisms involved. LRRC15 was overexpressed in the synovial tissues of patients with RA, and LRRC15 overexpression was associated with increased proliferative, migratory, invasive, and angiogenic capacities of RA-FLS and accelerated release of pro-inflammatory cytokines. LRRC15 knockdown significantly inhibited synovial proliferation and reduced bone invasion and destruction in CIA mice. Runt-related transcription factor 1 (RUNX1) transcriptionally represses LRRC15 by binding to core-binding factor subunit beta (CBF-β). Overexpression of RUNX1 significantly inhibited the invasive phenotype of RA-FLS and suppressed the expression of proinflammatory cytokines. Conversely, the effects of RUNX1 were significantly reversed after overexpression of LRRC15 or inhibition of RUNX1-CBF-β interactions. Therefore, we demonstrated that RUNX1-mediated transcriptional repression of LRRC15 inhibited the development of RA, which may have therapeutic effects for RA patients.

Policy Model for Securing and Utilizing Foreign Brains - focusing on the Higher Education - (외국인 인재 유치 및 활용을 위한 정책 모형 연구 - 고등교육기관을 중심으로 -)

  • Shin, Jun-Woo;Kwon, Jang-Woo;Lee, Jung-Mann
    • The Journal of the Korea Contents Association
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    • v.10 no.3
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    • pp.423-435
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    • 2010
  • The number of professionals in the science and engineering fields decreases all over the world. Especially in Korea, the declining rate of both the laborable and economically active population, aging of the population at the fastest level, and the declining birth rate make it tougher to secure the core brains of the future. After speculation of all programs above, some common factors have been derived and every program appeared to have the support for each level of inducing, caring, and utilizing. And the means of support could be categorized into the financial, legal, and social aspects. Lastly, a logical tool called Systems Thinking has been applied to the FLS Conditions and the Brain Internalization Process to assure the efficacy and applicability of the models. This is to minimize any de facto side effects by analyzing all 'feedback loops' stemming from the models. And the 'causal loop diagrams' have been utilized to come with the complementary measures. Such series of verification could convince the virtue of the models. Governments and universities can make use of the FLS Conditions and the Brain Internalization Process so the policies or plans about the foreign brains can be built in a uniformized and consistent framework. I hope, as a result, the international competency of Korea to induce and utilize the foreign brains be raised with the constant and standardized formality.

Semi-Rig, Introduction of Hole Verification Procedure (Semi- Rig, Hole Verification Procedure 소개)

  • Lee, Seung-hun;Lee, Seung-hun;Kang, Young-gu;Lee, Joon-hyuk
    • Special Issue of the Society of Naval Architects of Korea
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    • 2017.10a
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    • pp.32-37
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    • 2017
  • Due to the nature of semi-submergible drilling rig, various equipments are arranged in a limited space, and therefore the many types of outfitting holes passing through the hull structure are densely arranged and that is required the detailed structural strength evaluation in terms of ULS and FLS by class or client. Particularly, semi-submergible drilling rig has a variety of global load which affects the structure strength around holes compared to general commercial ship, and its response of stress is also complicated, so it is difficult to carry out the prediction design of structural strength evaluation and reinforcement. In this regard, this paper presents a case study on the evaluation of structural strength for the various holes and large openings of semi-submergible drilling rig conducted by our company, as well as an established hole verification procedure.

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Accumulation of Flavonols in Response to Ultraviolet-B Irradiation in Soybean Is Related to Induction of Flavanone 3-β-Hydroxylase and Flavonol Synthase

  • Kim, Bong Gyu;Kim, Jeong Ho;Kim, Jiyoung;Lee, Choonghwan;Ahn, Joong-Hoon
    • Molecules and Cells
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    • v.25 no.2
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    • pp.247-252
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    • 2008
  • There are several branch points in the flavonoid synthesis pathway starting from chalcone. Among them, the hydroxylation of flavanone is a key step leading to flavonol and anthocyanin. The flavanone 3-${\beta}$-hydroxylase (GmF3H) gene was cloned from soybean (Glycine max cultivar Sinpaldal) and shown to convert eriodictyol and naringenin into taxifolin and dihydrokaempferol, respectively. The major flavonoids in this soybean cultivar were found by LC-MS/MS to be kamepferol O-triglycosides and O-diglycosides. Expression of GmF3H and flavonol synthase (GmFLS) was induced by ultraviolet-B (UV-B) irradiation and their expression stimulated accumulation of kaempferol glycones. Thus, GmF3H and GmFLS appear to be key enzymes in the biosynthesis of the UV-protectant, kaempferol.

Luminescent Characteristics of External Electrode Fluorescent Lamp(EEFL) for LCD Backlight Applications (LCD Backlight용 외부전극 형광램프의 발광특성)

  • 이순석;임성규
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.39 no.12
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    • pp.1016-1021
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    • 2002
  • Luminescent characteristics of FLs were studied according to the structure of electrode for LCD backlight applications. The luminance and luminous efficiency of the FLs fabricated under same conditions were measured and evaluated as functions of magnitude of applied voltage and widths of external electrode. The luminance and luminous efficiency of CCFL at 12 V were 27600 cd/$m^2$ and 35.3 lm/w, respectively The luminance of EEFLS increased as the widths of external electrode increased, and the luminous efficiency of EEFLS showed to increase to 20 mm of electrode width) and to decrease at wider than 20 m of electrode widths. The luminance and luminous efficiency of EEFL with 20 mm of electrode widths were 21600 cd/$m^2$ and 26500 cd/$m^2$, 35.6 lm/w and 34.8 lm/w at 12 V, 14 V, respectively.

Immunosuppression Associated with Ovine Foetal Skin Extracts (면양태아피부추출액(緬羊胎兒皮膚抽出液)의 세포면역(細胞免疫) 기능저하(機能低下) 효과(效果)에 관(關)한 연구(硏究))

  • Jun, Moo Hyung
    • Korean Journal of Agricultural Science
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    • v.11 no.2
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    • pp.344-351
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    • 1984
  • Crude 3 M KCI extracts of ovine foetal skin (FLS) were shown to induce serum inhibition of lymphocyte blastogenesis when injected to normal sheep. When fractionated through Sephadex C-150 columns, four protein peaks were obtained, immunosuppressive activity in vitro and in vivo being associated with Peak IV. In discussion, the immunosuppressive activity of FLS is compared with that obtained with extracts of ovine squamous cell carcinoma, and possible identity of the immunosuppressors is suggested.

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Differential Responses of Soybean Cultivars to Cercospora sojina Isolates, the Causal Agent of Frogeye Leaf Spot in Korea

  • Kim, Ji-Seong;Lee, Young-Su;Kim, Sung-Kee;Kim, Ki-Deok;Kim, Jin-Won
    • The Plant Pathology Journal
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    • v.27 no.2
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    • pp.183-186
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    • 2011
  • During the summer of 2005, specimens of soybean cultivars (Daepung, Daewon, Hwanggeum and Taegwang) showing frogeye leaf spot (FLS) were obtained from various areas in Korea. Eight isolates identified as Cercospora sojina were inoculated on the adaxial leaf surfaces of 63 Korean soybean cultivars; the disease responses to each isolate were evaluated 14 days and 21 days after inoculation. Based on the disease responses (resistant or susceptible) of the cultivars by the isolates, a set of cultivars (Anpeong, Bogwang, Cheongdu No. 1, Cheongja No. 3, Dachae, Daemang, Jangwon, Namhae, Sowon, Taegwang) were selected and inoculated with seven isolates for further testing pathogenic variance. Interestingly, 6 out of 7 tested C. sojina isolates revealed differential ability in infecting different soybean cultivars. This result may indicate the possibility of new race occurrence or pathogenic variation; this also presents evidence for prevalent FLS occurrence during humid and hot weather in Korea.

Autonomous swimming technology for an AUV operating in the underwater jacket structure environment

  • Li, Ji-Hong;Park, Daegil;Ki, Geonhui
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.11 no.2
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    • pp.679-687
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    • 2019
  • This paper presents the autonomous swimming technology developed for an Autonomous Underwater Vehicle (AUV) operating in the underwater jacket structure environment. To prevent the position divergence of the inertial navigation system constructed for the primary navigation solution for the vehicle, we've developed kinds of marker-recognition based underwater localization methods using both of optical and acoustic cameras. However, these two methods all require the artificial markers to be located near to the cameras mounted on the vehicle. Therefore, in the case of the vehicle far away from the structure where the markers are usually mounted on, we may need alternative position-aiding solution to guarantee the navigation accuracy. For this purpose, we develop a sonar image processing based underwater localization method using a Forward Looking Sonar (FLS) mounted in front of the vehicle. The primary purpose of this FLS is to detect the obstacles in front of the vehicle. According to the detected obstacle(s), we apply an Occupancy Grid Map (OGM) based path planning algorithm to derive an obstacle collision-free reference path. Experimental studies are carried out in the water tank and also in the Pohang Yeongilman port sea environment to demonstrate the effectiveness of the proposed autonomous swimming technology.

Study on the Effect of Geopungjeseup-tang in Rheumatoid Arthritis (거풍제습탕(祛風除濕湯)의 류마토이드 관절염 치료효과에 대한 실험적 연구)

  • Hong, Sun-Sung;Yoon, Il-Ji;Oh, Min-Suck
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.5
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    • pp.1241-1244
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    • 2006
  • This study was carried out to know the effect of Geopungjeseup-tang(GPJST) to on Rheumatoid Arthritis by using human fibroblast-like synoviocytes(hFLS). GPJST consists of Coisis Semen, Coccllus Trilobus DC., Lycopi Herba, Arisaematis Rhizoma. The author peformed several experimetal items : that is cytotoxicity of GPJST, mRNA expression of TNF-${\alpha}$, IL-1${\beta}$, ICAM-1, production of NO. The results were obtained as follows : The mRNA expression of pro-inflammatory cytokines TNF-${\alpha}$, IL-1${\beta}$, ICAM-1 were dose-dependently reduced in hFLS. The production of NO was reduced. Talking all these observations into account, GPJST is considered to be effective in treating rheumatoid arthritis. Therefore we have to survey continuously in looking for the effective substance and mechanism in the future.