• 대한전기학회:학술대회논문집
• /
• 대한전기학회 2005년도 학술대회 논문집 정보 및 제어부문
• /
• pp.328-330
• /
• 2005

Most of the water level controllers of the actual plant are PID controllers. But they have limitations in appling for tracking the set point and getting rid of disturbances, so there are some defects to apply in the actual ground even though many research works represented the resolution to solve it. In this paper, we design a fuzzy logic system (FLS) for controlling the steam generator water level in nuclear power plants. Some computer simulations reveal similar performance with the conventional PID controller.

• Journal of Plant Biotechnology
• /
• 제38권4호
• /
• pp.278-284
• /
• 2011

The CCR4-CAF1-NOT complex-mediated degradation of mRNA is a fundamental aspect of gene regulation in eukaryotes. We herein examined the role of AtCAF1 in the innate immune and wound responses of plants. Our results showed that overexpression of AtCAF1 significantly downregulated the transcript level of EFR but not FLS2 and BRI1, as well as abolished up-regulated expression pattern of EFR in response to wounding. Consistently, Agrobacteriummediated transient expression of GUS was highly enhanced in the transgenic plants overexpressing AtCAF. Furthermore, JA responsive genes were down-regulated by overexpression of AtCAF, causing the transgenic plants overexpressing AtCAF more susceptible to necrotrophic fungal pathogen, Botrytis cinerea. These results suggest that The CCR4-CAF1-NOT complex-mediated degradation of mRNA negatively regulates wounding-mediated disease resistance in Arabidopsis thaliana.

• Journal of the Optical Society of Korea
• /
• 제20권1호
• /
• pp.204-211
• /
• 2016

Oil pollution seriously endangers the biological environment and human health. Due to the diversity of oils and the complexity of oil composition, it is of great significance to identify the oil contaminants. The 3-D fluorescence spectrum combined with a second order correction algorithm was adopted to measure an oil mixture with overlapped fluorescence spectra. The self-weighted alternating trilinear decomposition (SWATLD) is a kind of second order correction, which has developed rapidly in recent years. Micellar solutions of #0 diesel, #93 gasoline and ordinary kerosene in different concentrations were made up. The 3-D fluorescence spectra of the mixed oil solutions were measured by a FLS920 fluorescence spectrometer. The SWATLD algorithm was applied to decompose the spectrum data. The predict concentration and recovery rate obtained by the experiment show that the SWATLD algorithm has advantages of insensitivity to component number and high resolution for mixed oils.

• 천문학회보
• /
• 제35권1호
• /
• pp.77.1-77.1
• /
• 2010

I summarize highlights from extragalactic research activities performed with AKARI infrared space telescope. The main emphasis will be given to the works carried out by Korean astronomers. The activities span a wide range of topics, such as MIR properties of nearby galaxies in cluster environment, MIR diagnosis of star-forming galaxies at z=0 through z=2 in the North Ecliptic Pole (NEP) survey field, the Extended Groth Strip (EGS), and the First Look Survey (FLS) field, and the NIR spectroscopy of Luminous Infrared Galaxies (LIRGs) and Active Galactic Nuclei/Super-massive Black Holes at low redshift as well as near the re-ionization epoch of z~6. I describe FIR and MIR all sky data which can be used as a precious resource for extragalactic research, and other future and ongoing works with AKARI. These AKARI results will form a strong basis for future studies using other facilities, such as infrared surveys with UKIRT, FIR study of dusty universe with Herschel, and the SPICA mission.

• 한국지능시스템학회논문지
• /
• 제18권1호
• /
• pp.109-115
• /
• 2008

무인자동차에 관한 연구가 활성화되면서 무인 주차 또한 중요한 과제로 대두되고 있다. 본 논문에서는 무인차랑을 위한 주차 편의 시스템 설계를 위하여 퍼지논리시스템에 의한 주차 알고리즘 설계를 제안하고자 한다. 기존의 논문들이 제시한 장단점을 분석하여 새로운 단일 입력을 가지는 퍼지논리시스템을 통한 주차 알고리즘을 설계하고, 시뮬레이션을 통하여 그 효용성을 확인하고자 한다.

• IMMUNE NETWORK
• /
• 제8권1호
• /
• pp.29-37
• /
• 2008

Interleukin-23 (IL-23) is a novel pro-inflammatory cytokine which has been implicated to play a pathogenic role in rheumatoid arthritis (RA). This study was undertaken to investigate the IL-23 inductive activity of the proinflammatory cytokine IL-17, $IL-1{\beta}$ and tumor necrosis factor (TNF-${\alpha}$) in RA synovial fluid mononuclear cells (SFMC). Expression of IL-23p19, IL-17, $IL-1{\beta}$ and TNF-${\alpha}$ in joint was examined by immunohistochemistry (IHC) of patients with RA and osteoarthritis (OA). The effects of IL-17 and $IL-1{\beta}$ on expression of IL-23p19 in human SFMC from RA patients were determined by reverse transcriptase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA). IL-23p19 was expressed in the RA fibroblast like synoviocyte (FLS), but not from OA FLS. Similar to the protein expression, IL-23p19 mRNA could be detected by RT-PCR in RA SFMC. IL-17 and $IL-1{\beta}$ could induce RA SFMC to produce the IL-23p19. The effects of IL-17 were much stronger than $IL-1{\beta}$ or TNF-${\alpha}$. These responses were observed in a doseresponsive manner. In addition, IL-17 or $IL-1{\beta}$ neutralizing antibody down-regulated the expression of IL-23p19 induced by LPS in RA-SFMC. Our results demonstrate that IL-23p19 is overexpressed in RA synovium and IL-17 and $IL-1{\beta}$ appears to upregulate the expression of IL-23p19 in RA-SFMC.

• 생명과학회지
• /
• 제22권8호
• /
• pp.1034-1040
• /
• 2012

활막조직은 관절부위에 존재하는 비연골성의 얇은 세포층으로 구성되어 있으며, 류마티스 관절염 등에서 활성화 되어진다. 우리는 골관절염(n=8)과 류마티스 관절염(n=5)에서 유래한 활막조직을 대상으로 활막조직내의 세포를 정량화하고 세포성분들을 비교 분석하고자 하였다. 활막조직을 H&E 염색한 후 광학현미경으로 관찰하였을 때 류마티스 관절염의 활막조직은 골관절염에 비해 형태적으로 두터워졌으며 비후된 양상이었다. 또한 CD68, CD90, PGP9.5 등과 마커들을 이용하여 IHC 분석을 수행한 결과 활막조직의 내막층과 내막하층에 존재하는 세포들을 특성을 분한 결과 내막층에는 대식세포가 집중적으로 분포하며, 내막하층에는 대식세포와 섬유아세포 유사 활막세포(FLS)가 존재한다는 사실을 알 수 있었다. H&E 이미지를 포토샵 프로그램을 이용하여 반전시켜 내막층과 내막하층 부위별로 세포계수 및 세포층계수를 수행하였다. 내막층 분석 결과 류마티스 관절염의 활막조직의 골괄절염보다 대식세포의 수와 층이 현저하게 증가된 것을 확인할수 있었다. 또한 류마티스 관절염의 활막조직의 내막하층분석결과 섬유아세포 유사 활막세포의 수적인 증가를 계수 할 수 있었다. 또한 류마티스 관절염의 경우 활막의 비후가 심하기 때문에 혈관의 위치가 내막층으로부터 상대적으로 멀리 위치하고 있음을 알 수 있었다. 그러므로 H&E 염색 이미지의 포토샵 분석을 이용한 골관절염과 류마티스 관절염 활막조직에 대한 정량 분석 방법은 류마티스 관절염의 발병과정에서 세포들이 활성화된다는 사실을 증명하는데 유용할 것으로 사료된다.

• 한국식물병리학회:학술대회논문집
• /
• 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
• /
• pp.82-83
• /
• 2003

Plants have evolved differently from animals having mobile activities. Thus, plants should have developed unique defense mechanisms against biotic/abiotic stresses to which plants are differently exposed, according to seasons. Most organisms have an conserved signaling network using mitogen-activated protein kinase (MAPK) cascade(s). The phenomenon implied that they are functionally very important in all organisms. In fact, they constitute one of the major components of signaling pathways involved in regulating a wide range of cellular activities from growth and development to cell death. Recently, complete MAPK cascade was first characterized in Arabidopsis from the receptor kinase (FLS2) through fellowing MEKKI -MKK4/MKK5-MPK3/MPK6-WRKY22/MRKY29 pathway. Whereas, MAPK cascade signaling pathway in monocot plant including rice (0ryza sativa L.), the most important of all food crops and an established monocot plant research model, MAPKinase kinase kinases (MAPKKK) of rice are the first upstream component of the MAPK cascade, but MAPKKK has been first identified and characterized in our lab and designated as, OsEDRl based on its homology with the Arabidopsis EDRI. The Arabidopsis EDRl was regarded as a negative regulator of defense response and the role of rice OsEDRl was analyzed. Transcriptional regulation of OsEDRl was detected under various stresses and immunoblotting analysis is going on to detect the level of OsEDRl protein in the mutants showing unique phenotype. We also introduced the constitutively active and the dominant negative forms of the OsEDRl for characterizing biological function.

• Molecules and Cells
• /
• 제19권2호
• /
• pp.180-184
• /
• 2005

IL-17 is a major proinflammatory cytokine secreted by activated T-lymphocytes that accumulates in the inflamed joints of rheumatoid arthritis (RA) patients. Additional IL-17-related molecules and their receptors have been discovered and may also contribute to RA pathogenesis. We examined the expression of the prototypic IL-17 (IL-17A) and its homologs, IL-17B-F, by RT-PCR analyses of synovial fluid mononuclear cells (SFMCs) and peripheral blood mononuclear cells (PBMCs) from RA patients. We also tested for induction of the IL-17 receptor homologs upon stimulation of the fibroblast-like synoviocytes (FLSs) of RA patients with IL-17. The patients' SFMCs expressed IL-17C, E and F in addition to IL-17A. As in the case of IL-17, IL-15 appears to be the major inducer of these homologs in RA SFMCs. We detected transcripts of IL-17R, as well as those of IL-17RB, C and D, in the FLSs of RA patients. Whereas IL-17R expression increased upon in vitro stimulation with IL-17, expression of IL-17RB, C and D was unchanged. However the possibility of cross-interaction between other IL-17 homologs and receptor isoforms remains to be investigated. Our data suggest that these additional homologs should also be considered as targets for immune modulation in the treatment of RA joint inflammation.

• 천문학회보
• /
• 제39권2호
• /
• pp.53.2-53.2
• /
• 2014

Radial color gradient of early type galaxies (ETGs) is a key tool for studying the evolution of these galaxies. In this work, we investigated whether ETGs having negative or positive color gradients show any distinguishable characteristics in the galaxy properties. We selected sample of 211 ETGs at 0.01 < z < 0.5 in the Spitzer FLS field, then we constructed u-R color gradients. We obtained the stellar mass, specific star formation rate and fluxes of emission lines of each ETG from MPA-JHU DR7 catalog. Spitzer IRAC and MIPS 24 micron data were used to detect dust emission from the ETGs. Preliminary result shows that less massive galaxies are likely to have positive color gradients, which is probably due to the ongoing star formation in the galaxy core. Almost all AGNs have negative color gradients. This probably is because AGNs are located in relatively massive galaxies with little ongoing star formation. There exists a marginal difference in the percentage of galaxies with PAH emission between ETGs having positive color gradient and negative color gradient. This also supports that ETGs with positive color gradient are galaxies having enhanced star formation.