• The Journal of Internal Korean Medicine
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• v.41 no.5
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• pp.769-776
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• 2020

Objective: This case study reports improvement in a case of Guillain-Barre Syndrome by Korean medicine treatment in a patient with quadriplegia and anorexia. Methods: A 79-year-old woman diagnosed with Guillain-Barre Syndrome was treated with acupuncture, electroacupuncture, Bojungikgi-tang-gami, cupping, moxibustion, and rehabilitation. Her clinical symptoms were measured with the Manual Muscle Test (MMT), Modified Barthel Index (MBI), Functional Independence Measurement (FIM), and the EuroQol five-dimensional descriptive system (EQ-5D-5L). Results: After treatment, improvements in the MMT, MBI, FIM, and EQ-5D-5L were observed and her anorexia decreased. Conclusion: Korean medicine treatment appeared to be effective in the treatment of a patient with Guillain-Barre Syndrome with quadriplegia and anorexia.

• Korean Institute of Interior Design Journal
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• v.20 no.3
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• pp.242-248
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• 2011

According to a study on the accident patterns of older people in 2006 by Korea Consumer Agency (CISS), the number of accidents of the elderly at home reached 486, and the figure has increased every year. As Korea is about to enter into the aged society, it is important to investigate the factors that cause an accident in the welfare facilities for the aged and establish the barrier-free construction standards. The accident influence factors include facility environmental, physical functional, socio demographic and socio psychological factors. In terms of the verification tools, there are Facility Evaluation Index, FIM, MMSE-K and General Feature. In terms of analysis method, in addition, there are real number, percentage, t-test, ANOVA and logistic regression. In conclusion, this paper attempts to reveal correlations among the accident influence factors using the Facility Evaluation Standards (115 items in total) for facility environmental factor, FIM (3 items) for physical functional factor, MMSE-K (6 items) for socio psychological factor and questionnaire (5 items) for socio demographic factor.

• The Journal of Korean Physical Therapy
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• v.19 no.5
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• pp.87-96
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• 2007

Purpose: It remains controversial for the effect of daily functioning and quality of life on therapeutic exercise after stroke. The purpose of this study was to describe the effects on daily functioning and QOL. Methods: Outcome measures of daily functioning included, such as the Functional Independence Measure (FIM), Barthel index. Outcome measures of QOL included, such as Stroke Impact Scale(SIS) and the Medical Outcomes Study short-form 36-item questionnaire(SF-36). Results: 125 stroke patients were recruited, who were in or outpatients. The average age was 55.4 years. 64.8% were male. The mean Bathel index and FIM score was 63.7 and 87.5. The mean SIS score were higher in communication and mean SF-36 score were higher in physical pain. In/out patients are associated with SIS (communication, emotion) and SF-36(social function, energy or fatigue). Sex are associated with SF-36 (physical function). Other disease state are associated with SIS(hand function) and SF-36 (physical function). Paralysis portion are associated with SIS(communication, daily activity). Barthel index are associated with SIS(communication, mobility) and SF-36(social function, physical function, role limits due to emotional problems). Conclusion: These findings may provide the useful with rehabilitation professionals, who specilalized in the importance of QOL in designing treatment modalities.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.6
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• pp.842-846
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• 2013

The purpose of this study was to report one clinical case of spinocerebellar ataxia(SCA) type 1 improved by herbal medicine and oriental medical treatment. As a treatment, Yukmijihwang-tang(Liuweidihuangtang)-gamibang, acupuncture, and moxa were tried upon the patient for 21 days in order to relieve the symptoms. In terms of observing the changes of symptoms, the progress of patient's condition was evaluated periodically by using the Korean-mini mental state examination(K-MMSE), Modified Barthel Index(MBI), Functional Independence Measure(FIM). In accordance with the observation under K-MMSE, MBI, FIM, the patient's symptoms had gradually improved throughout the treatment. Therefore, this report suggests that Yukmijihwang-tang(Liuweidihuangtang)-gamibang, acupuncture and moxa were probably effective in the treatment of SCA type 1.

• Journal of Oriental Neuropsychiatry
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• v.26 no.3
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• pp.307-318
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• 2015

Objectives: This study evaluated the effect of oriental treatments and rehabilitation on a patient with organic mental disorder after head trauma caused by traffic accident. Methods: We treated the patient with acupuncture, herb-medication, oriental psychotherapy, and rehabilitation. MMSE-K, BDI, K-MBI, FIM were evaluated before and after treatment. Results: The results indicated that MMSE-K was maintained at 27 points; BDI was reduced from 16 points to 5 points; K-MBI was increased from 75 points to 99 points; and FIM was increased from 86 points to 115 points. Furthermore, the treatment resulted in reduced mental symptoms and improved work capacity. Conclusions: Oriental medical treatment has potential validity in improving symptoms of organic mental disorder.

• Journal of The Korean Society of Integrative Medicine
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• v.4 no.1
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• pp.21-29
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• 2016

Purpose : The purpose of this study was to evaluate the influence of LOTCA-G and ADL by individualized cognitive program in elderly with vascular dementia, alzheimer dementia and mild cognitive impairment. Method : The subjects of this study, old man and woman diagnosed with vascular dementia, alzheimer dementia and mild cognitive impairment, 24 patients were picked up, who were agreed with this research and were having hospital care for 3weeks at nursing care centers. Individualized cognitive program was applied to 8 patients of vascular dementia, 8 patients of alzheimer dementia and 8 patients of mild cognitive impairment. Cognitive function measured by LOTCA-G and performance measured by FIM. The SPSS Ver. 22.0 statistical program was used for data processing. The significance level for statistical inspection was set as 0.05. Result : In comparison of LOTCA-G was significant increased after intervention and among three groups were significant difference. But FIM was no significant difference after intervention and among three groups were no significant difference. Conclusion : Therefore, the individualized cognitive program is useful to improve the cognitive function in elderly with dementia and mild cognitive impairment.

• Korean Journal of Adult Nursing
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• v.20 no.2
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• pp.239-250
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• 2008

Purpose: The purpose of this study was to determine the effect of a 2-week somatosensory stimulation program on cognitive function and ADL of patients with brain damage. Methods: The sample consisted of two groups of patients with stroke: 10 patients with a mean age of 59.0 years who were treated with somatosensory stimulation, and 9 patients with a mean age of 51.78 years, who were not treated with somatosensory intervention. A nonequivalent control group non-synchronized design was used to assess the functional recovery after stroke. Instruments used in this study were MMSE-K for cognitive function and FIM for ADL. Results: The hypothesis 1 that "Patients with stroke who were treated with the somatosensory stimulation program will show higher MMSE-K score than that of the non-treatment group" was supported(Z = -2.390, p = .017). The hypothesis 2 that "Patients with stroke who were treated with the somatosensory stimulation program will show higher FIM score than that of the non-treatment group", however, was partially supported(social cognition: Z = -2.204, p = .045). Conclusion: Somatosensory stimulation was effective to patients with stroke in improving their cognitive function. These findings suggest that somatosensory input can be adopted to nursing intervention for functional recovery after stroke.

• Biomolecules & Therapeutics
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• v.12 no.3
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• pp.179-184
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• 2004

The FimH subunit of type 1-fimbriated Escherichia coli has been determined as a major cause for urinary tract infections. In our previous study, the Adhesin/CTXA2B was expressed as soluble recombinant chimaeric protein derived from the uropathogenic Escherichia coli adhesin genetically coupled to cholera toxin A2B (CTXA2B) subunit in Escherichia coli. Since it is very important to optimize IPTG concentration and culture temperature to maximize cell growth and productivity, These optimal culture factors were determined to increase the productivity of the expressed Adhesin/CTXA2B chimaeric protein in Escherichia coli TB1 carrying pMALfimH/ctxa2b. Our data demonstrate that optimal concentration of IPTG for increased production of chimaeric protein was 0.5 mM. Additionally, culture time was 10 hours and temperature, 37${\circ}C$.

• Journal of the Korean Society of Physical Medicine
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• v.8 no.2
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• pp.175-182
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• 2013

PURPOSE: The purpose of this study was to investigate the effects of task oriented ADL exercise in different environments in patients with chronic stroke. METHODS: A total of 28 patients with hemiplegia resulting from stroke were included in this study. The patients were randomized into two groups. The control group(n=14) was received neurodevelopment therapy + task oriented ADL exercise and experimental group(n=14) was received neurodevelopment therapy + home based task oriented ADL exercise for 30 minutes twice per week during 6weeks. A task oriented ADL exercise pretest and postest design was used examine the change of FIM(Functional Independent Measure) and K-MBI(Korea-Modified Bathel Index) at the completion of 6 weeks task oriented ADL exercise. RESULTS: After 6 weeks, the experimental group compared with control group showed a significant improvement (p<.05) in FIM and K-MBI scores. CONCLUSION: The results indicate that the home based task oriented ADL exercise improves functions in the persons with chronic stroke.

• Journal of the Korean Society of Physical Medicine
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• v.6 no.2
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• pp.225-233
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• 2011

Purpose: This study evaluated the feasibility of using Nintendo Wii games for improving cognition, balance, function in patients with dementia. Methods: A total 30 dementia patients were randomly assigned into the experimental group(n=15) and control group(n=15). All subjects performed a general therapeutic exercise, and 30-minute sessions of the table tennis and fencing game of Nintendo Wii were conducted with experimental group 3 times a week for 8 weeks. The intervention effects were measured by using MMSE-K, BBS, and FIM. The results were analyzed by using repeated measure ANOVA. Results: The MMSE-K and BBS scores showed significant differences. A significant interaction was observed between the experimental group and the control group in MMSE-K. The final MMSE-K and BBS scores for the experimental group were significantly higher than those for the control group. However, there was no difference in the FIM scores. Conclusion: We suggest that Nintendo Wii games are effective in cognㅇition and balance improvement in dementia patients. Future research on a variety of programs in needed.