• 제목/요약/키워드: FDA system

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제약산업에서 FDA규제 영향에 관한 시스템 다이내믹스 모델링: FDA규제가 R&D비용에 미치는 영향을 중심으로 (System Dynamics Modeling for FDA Regulation Effect of Pharmaceutical Industry)

  • 고성필;최정환;남동욱;이정동
    • 한국시스템다이내믹스연구
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    • 제13권4호
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    • pp.57-80
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    • 2012
  • This research studies effect of FDA regulations in pharmaceutical industry on new drug development. System dynamics is implemented to demonstrate dynamic relationship between FDA regulations and R&D costs, firm's profits, sales. This research is focused on clinical trials of new medical entity process 50~60% portion of total development cost. Simulation results say that firm's profit is more sensitive to increasing the regulation than alleviating the regulation and effect of regulation policy make different result depending on the intensity of regulation and policy direction. Our simulation model provides the instrumental means for the policy makers and strategic decision in pharmaceutical industry.

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시설용수 및 영농편의용수 공급시스템 개발 (I) - FDA 시스템 개발 - (Development of Clean Water Supplying System for Greenhouse Cultivation and Convenience Water (I) - Development of the FDA System -)

  • 이광야;최경숙
    • 한국농공학회논문집
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    • 제51권5호
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    • pp.95-100
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    • 2009
  • The water purification systems have been hardly used for agricultural purpose due to their complicated compositions and high costs for farmers, while only simple filtrations have been applied to irrigation systems in order to prevent the system from clogging problems. This study therefore developed a clean water supplying system, the Filter-Disinfection-Adsorption (FDA) system, especially for greenhouse cultivation of where low quality of water is available. This system has also been produced for providing convenience water to farmers in the areas of no water supply service systems for the purpose of washing their bodies or agricultural machineries after farm work. The FDA system consists of three stages of purification processes with an integral module, including disk and teflon filtrations and Ultraviolet (UV) sterilization processes. Indoor experiments were undertaken with a trial product of the FDA system to test its performance. The operation test of the process was performed as well as the condition check of each item including UV module, filters, control panel, pump, valves, etc. The results shows good performance of each test with no critical problems. The initial and maintenance costs were also analysed with other purification systems. From the comparisons, the FDA system found to be very economical and easy to use.

시설용수 및 영농편의용수 공급시스템 개발 (II) - FDA 시스템 현장적용성 평가 - (Development of Clean Water Supplying System for Greenhouse Cultivation and Convenience Water (II) - Assessment of the FDA System through a Site Application -)

  • 이광야;최경숙
    • 한국농공학회논문집
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    • 제51권5호
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    • pp.101-106
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    • 2009
  • The previous study developed the Filter-Disinfection-Adsorption (FDA) system to provide clean irrigation water for greenhouse cultivation as well as convenience water to farmers. In this study, the field examination was undertaken to assess performance of the FDA system. The field application was made in the suburb of Daegu, one of the large city in Korea. The study area located near by down-stream of Gum-Ho river is suffering low irrigation water quality problems with no water supply service facilities. Four water quality parameters including Suspended Solid (SS), Biological Oxygen Demand (BOD), coliform, and turbidity were selected to test the purification performance of FDA system. Also in order to improve the system, this study investigated the defects of using the FDA system through field monitoring. As results, it was found that this system can be used to supply good quality of irrigation water for greenhouse cultivation and also provide convenience water to farmers in the field areas of no water supply services.

Implementation and Test of the Automatic Flight Dynamics Operations for Geostationary Satellite Mission

  • Park, Sang-Wook;Lee, Young-Ran;Lee, Byoung-Sun;Hwang, Yoo-La;Galilea, Javier Santiago Noguero
    • Journal of Astronomy and Space Sciences
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    • 제26권4호
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    • pp.635-642
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    • 2009
  • This paper describes the Flight Dynamics Automation (FDA) system for COMS Flight Dynamics System (FDS) and its test result in terms of the performance of the automation jobs. FDA controls the flight dynamics functions such as orbit determination, orbit prediction, event prediction, and fuel accounting. The designed FDA is independent from the specific characteristics which are defined by spacecraft manufacturer or specific satellite missions. Therefore, FDA could easily links its autonomous job control functions to any satellite mission control system with some interface modification. By adding autonomous system along with flight dynamics system, it decreases the operator's tedious and repeated jobs but increase the usability and reliability of the system. Therefore, FDA is used to improve the completeness of whole mission control system's quality. The FDA is applied to the real flight dynamics system of a geostationary satellite, COMS and the experimental test is performed. The experimental result shows the stability and reliability of the mission control operations through the automatic job control.

IP-USN 기반의 홈 네트워크 환경에서 결함 감지 에이전트를 위한 신뢰성 (Reliability for A Fault-Detection Agent running on Home Network Environment based IP-USN)

  • 고응남
    • 한국항행학회논문지
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    • 제13권1호
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    • pp.74-78
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    • 2009
  • 본 논문은 IP-USN 기반의 FDA(Fault Detection Agent)의 설계와 구축을 설명한다. FDA는 IP-USN 기반의 홈 네트워크 환경에서 멀티미디어 원격 교육을 위한 소프트웨어 오류를 감지하기에 적합한 에이전트이다. 이 시스템은 ED, ES로 구성되어 있다. ED는 IP-USN 기반 환경에서 멀티미디어 원격 교육을 위하여 훅킹 기법으로 오류를 감지하는 에이전트이다. ES는 IP-USN 기반 환경에서 멀티미디어 원격 교육을 위하여 오류를 공유하는 에이전트이다.

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Effects of in Utero Exposure of Di(n-butyl)phthalate and Flutamide on the Development of Reproductive Organs in Male Rats

  • Shin, Jae-Ho;Lee, Su-Jung;Kim, Tae-Sung;Moon, Hyun-Ju;Kang, Il-Hyun;Kim, In-Young;Whang, Sung-Jo;Han, Soon-Young
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2003년도 추계학술대회
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    • pp.181-181
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    • 2003
  • The aims of present study were to compare the effects of in utero exposure of several chemicals which have antiandrogenic characteristics on the development of reproductive organs and to investigate the specific mechanisms related to the abnormalities observed in the male reproductive system.(omitted)

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클라우드 컴퓨팅 공동 환경의 네스티드 세션관리에서의 응용 및 오류 훅킹 (An Application and Error Hooking running on Nested Session Management of Cloud Computing Collaboration Environment)

  • 고응남
    • 한국항행학회논문지
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    • 제16권1호
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    • pp.145-150
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    • 2012
  • 본 논문은 규칙-기반 DEVS 모델링과 시뮬레이션 기법을 사용하면서 클라우드 컴퓨팅 공동 환경의 네스티드 세션 관리에서의 오류 감지 시스템의 성능 분석을 설명한다. 본 논문은 FDA(Fault Detection Agent)의 설계와 구축을 설명한다. FDA는 클라우드 컴퓨팅 공동 환경의 네스티드 세션 관리에서 멀티미디어 원격 제어를 위한 소프트웨어 오류를 감지하기에 적합한 에이전트이다.

The Effect of 3-MCPD on Male Fertility and Sperm Parameters in Rats

  • Kwack, Seung-Jun;Kim, Soon-Sun;Rhee, Gyu-Seek;Lee, Rhee-Da;Chae, Soo-Young;Choi, Yo-Woo;Lee, Hyun-Joo;Park, Kui-Lea
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.114.2-115
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    • 2003
  • 3-Monochloro-1, 2-propanediol(3-MCPD) is a toxic compound, often present in different foods containing acid hydrolyzed(AH) protein, like seasonings and savory food products. In Korea, 3-MCPD is currently being a problem because of its toxicity in AH soybean sauce. The purpose of the present studies was to investigate the effects of 3-MCPD on male fertility, sperm and testosterone secretion. In vivo male fertility test was performed for observing the adverse effects of 3-MCPD on the function of male reproductive system and pregnancy outcome. (omitted)

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홈 네트워크 환경에서 원격 교육을 위한 결함 감지 에이전트 (A Fault-Detection Agent for Distance Education on Home Network Environment)

  • 김학준;고응남
    • 한국항행학회논문지
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    • 제11권3호
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    • pp.313-318
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    • 2007
  • 본 논문은 FDA(Fault Detection Agent)의 설계와 구축을 설명한다. FDA는 홈 네트워크 환경에서 멀티미디어 원격 교육을 위한 소프트웨어 오류를 감지하기에 적합한 에이전트이다. 이 시스템은 ED, ES로 구성되어 있다. ED는 홈 네트워크 환경에서 멀티미디어 원격 교육을 위하여 훅 킹 기법으로 오류를 감지하는 에이전트이다. ES는 홈 네트워크 환경에서 멀티미디어 원격 교육을 위하여 오류를 공유하는 에이전트이다. 멀티미디어 공동 작업 환경의 관점에서 오류 공유는 협동 작업에 참가하는 참가자에게 상호작용적으로 오류를 공유한다. 훅 킹 방법과 가로채기 방법과의 비교를 통하여 효율성 분석을 하였다.

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