• Journal of Pharmacopuncture
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• v.15 no.4
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• pp.32-41
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• 2012

Objectives: Rehmannia glutinosa pharmacopuncture solution (RGPS) was investigated to determine both its anti-allergic inflammatory effects on mast cells and its detailed mechanism of actions. Methods: We investigated whether RGPS suppress cytokines, enzymes, $Fc{\varepsilon}RI$ expression and $Fc{\varepsilon}RI$-mediated signaling in RBL-2H3 cells stimulated with anti-DNP IgE/DNP-HSA. The suppressive effects of RGPS on the levels of cytokines such as IL-$1{\beta}$, IL-6 and GM-CSF were measured using emzyme-linked immunospecific assay (ELISA). The mRNA expression levels of cytokines, enzymes (HDC2, COX-1, COX-2 and 5LO) and $Fc{\varepsilon}RI$ ${\alpha}{\beta}{\gamma}$ subunits were measured using reverse transcription polymerase chain reaction (RT-PCR) method. The activation of $Fc{\varepsilon}RI$-mediated signaling was examined using Western blot analyses. Results: RGPS suppressed production of proinflammatory cytokines (IL-$1{\beta}$, IL-6, and GM-CSF) in stimulated RBL-2H3 cells significantly (p < 0.05). RGPS also suppressed mRNA expression of inflammatory enzymes (HDC2, COX-1, COX-2, 5LO). In addition, mRNA expression levels of $Fc{\varepsilon}RI{\alpha}$, $Fc{\varepsilon}RI{\beta}$and $Fc{\varepsilon}RI{\gamma}$ were lowered by treatment with RGPS. Finally, RGPS prevented phosphrylation of Lyn, Syk, LAT, Gab2, PLC ${\gamma}1/2$, PI3K, Akt, cPLA2 and $I{\kappa}B{\alpha}$. Conclusions: RGPS effectively suppresses mast cell activations such as degranulation and inflammatory response via down-regulation of the $Fc{\varepsilon}RI$-mediated signaling pathways in IgE/Ag-stimulated mast cells.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.67 no.3
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• pp.147-154
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• 2022

This study was conducted by directly sowing Asemi in late April at 30 × 10 cm intervals to determine the optimal irrigation method and irrigation amount to maximize the use of limited agricultural water and to increase the yield when growing rice in a desert climate. Conventional irrigation (Conv.), surface drip irrigation (Sur), subsurface drip irrigation (Sub.), and sprinkler irrigation (Spr.) methods were used. The following amounts of irrigation were tested based on field capacity (0.33 bar): 80% (V/V, FC80), 100% (FC100), and 120% (FC120), and data for 2 years were averaged. The total amount of irrigation by irrigation method was the lowest, at 627 ton/10 a, for Sub. irrigation with the FC80 treatment, which was 60.4% less than the amount of irrigation with the FC120 treatment (1,584 ton/10a). Sub. irrigation with the FC120 treatment gave the greatest amount of rice, at 665 kg/10 a, and this condition obtained a yield of 88.1% (754 kg/10 a) of the yield obtained with the conventional treatment. Therefore, when planting rice in a desert climate, subsurface drip irrigation at 120% of field capacity is considered advantageous to increase water use efficiency and crop yield.

• Journal of Advanced Marine Engineering and Technology
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• v.38 no.9
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• pp.1032-1038
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• 2014

In this study, an experimental study was performed to understand the boiling heat transfer characteristics of FC-72 in parallel micro-channels. The parallel micro-channels contained channels having a $0.2mm{\times}0.45mm$ [$H{\times}W$] cross section and length of 60 mm. And heat flux was varied from 16.4 to $25.6kW/m^2$ and mass fluxes from 300 to $500kg/m^2s$. The measured heat transfer coefficient was sharply decreased at lower vapor quality and then it was kept approximately constant as the vapor quality is increased. From the experimental results, the boiling heat transfer mechanism of FC-72 was confirmed and the measured heat transfer coefficient was compared and analyzed with the existing correlations to predict the heat transfer coefficient.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.21 no.3
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• pp.189-195
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• 2018

Purpose: We investigated fecal calprotectin (FC) levels in preterm infants with and without feeding intolerance (FI), and compared the FC levels according to the type of feeding. Methods: The medical records of 67 premature infants were reviewed retrospectively. The fully enteral-fed infants were classified into two groups; the FI group (29 infants) and the control group (31 infants). Seven infants with necrotizing enterocolitis, sepsis, and perinatal asphyxia were excluded. If breast milk (BM) or preterm formula (PF) could not be tolerated by infants with FI, amino acid-based formula (AAF) was tried temporarily. Once FI improved, AAF was discontinued, and BM or PF was resumed. We investigated the FC levels according to the type of feeding. Results: Significant differences were found in gestational age, birth weight, age when full enteral feeding was achieved, and hospital stay between the FI and control group (p<0.05). The FC levels in the FI group were significantly higher than those in the control group (p<0.05). The FC levels in the AAF-fed infants with FI were significantly lower than those in the BM- or PF-fed infants (p<0.05). The growth velocities (g/d) and z scores were not significantly different between the FI and control group (p>0.05). Conclusion: The FC levels in AAF-fed infants with FI showed significantly lower than those in the BM- or PF-fed infants with FI. The mitigation of gut inflammation through the decrease of FC levels in AAF-fed infants with FI could be presumed.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.14 no.1
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• pp.93-99
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• 2014

This paper deals with the FC-MMA (Fast Convergence-Multi Modulus Algorithm) which is improving the convergence characteristics of the MMA (Multiple Modulus Algorithm) adaptive equalization algorithm that is used for the minimization of the intersymbol interference which occurs in the time dispersive communication channel. In the time varying charateristics and the abnormal situation like as outage of the communication channel, the adaptive equalizer needs to adapting the new environment more rapidly. For this problem, the residual isi and the maximum distortion performance index which are meaning the convergence characteristics are widely adapted in the adaptive equalizer. The 16-QAM signal is transmitted and it was confirmed that the proposed algorithm, the FC-MMA has the fast convergence performance such as in the 1.75 times fast in residual isi and 2.5 times fast in the maximum distortion in order to reaching the steady state compare to the MMA algorithm in the same channel environment by the computer simulation.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.11
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• pp.1770-1778
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• 2020

Objective: This study was conducted to reveal potential metabolic differences of dairy cows fed corn stover (CS) and rice straw (RS) instead of alfalfa hay (AH) as main forage source. Methods: Thirty multiparous mid-late lactation Holstein dairy cows were selected and randomly assigned to three diets, AH, CS, or RS (n = 10). After 13 weeks of the feeding trial, coccygeal arterial and superficial epigastric venous plasma samples were collected before morning feeding for gas chromatography time-of-flight/mass spectrometry analyses. Results: In the artery, 8 and 13 metabolites were detected as differential metabolites between AH and CS, and between AH and RS, respectively. The relative abundance of phenylpropanoate (log₂fold change [FC]) = 1.30, 1.09), panthenol (log₂FC = 2.36, 2.20), threitol (log₂FC = 1.00, 1.07), and 3,7,12-trihydroxycoprostane (log₂FC = 0.79, 0.78) were greater in both CS and RS than in AH, and tyrosine (log₂FC = -0.32), phenylalanine (log₂FC = -0.30), and pyruvic acid (log₂FC = -0.30) were lower in RS than in AH. In the vein, 1 and 7 metabolites were detected as differential metabolites between AH and CS, and between AH and RS, respectively. By comparing AH and RS, we found that metabolic pathways of phenylalanine, tyrosine, and tryptophan biosynthesis and phenylalanine metabolism were enriched by integrative artery and vein analysis. Furthermore, AH and RS, arterial phenylpropanoate and 4-hydroxyproline were positively, and phenylalanine was negatively correlated with milk urea nitrogen. Finally, in AH and CS, arterial panthenol was negatively correlated with feed efficiency. Conclusion: Arterial metabolic profiles changed more than those in the veins from animals on three forage diets, differing in amino acids. We found that phenylalanine, tyrosine, and tryptophan biosynthesis and phenylalanine metabolism were restricted when cows were fed low-quality cereal straw diets.

• Journal of Microbiology and Biotechnology
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• v.16 no.2
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• pp.232-239
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• 2006

The microbial activity and bacterial community structure of activated sludge reactors, which treated free cyanide (FC), zinc-complexed cyanide (ZC), or nickel-complexed cyanide (NC), were studied. The three reactors (designated as re-FC, re-ZC, and re-NC) were operated for 50 days with a stepwise decrease of hydraulic retention time. In the re-FC and re-ZC reactors, FC or ZC was almost completely removed, whereas approximately 80-87% of NC was removed in re-NC. This result might be attributed to the high toxicity of nickel released after degradation of NC. In the batch test, the sludges taken from re-FC and re-ZC completely degraded FC, ZC, and NC, whereas the sludge from re-NC degraded only NC. Although re-FC and re-ZC showed similar properties in regard to cyanide degradation, denaturing gradient gel electrophoresis (DGGE) analysis of the 16S rRNA gene of the bacterial communities in the three reactors showed that bacterial community was specifically acclimated to each reactor. We found several bacterial sequences in DGGE bands that showed high similarity to known cyanide-degrading bacteria such as Klebsiella spp., Acidovorax spp., and Achromobacter xylosoxidans. Flocforming microorganism might also be one of the major microorganisms, since many sequences related to Zoogloea, Microbacterium, and phylum TM7 were detected in all the reactors.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.25 no.12
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• pp.1821-1830
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• 2001

The flow around free end of a finite circular cylinder (FC) embedded in an atmospheric boundary layer has been investigated experimentally. The experiments were carried out in a closed-return type subsonic wind tunnel with varying aspect ratio of the finite cylinder mounted vertically on a flat plate. The wakes behind a 2-D cylinder and a finite cylinder located in a uniform flow were measured for comparison. Reynolds number based on the cylinder diameter was about Re=20,000. A hot-wire anemometer was employed to measure the wake velocity and the mean pressure distributions on the cylinder surface were also measured. The flow past the FC free end shows a complicated three-dimensional wake structure and flow phenomenon is quite different from that of 2-D cylinder. The three-dimensional flow structure was attributed to the downwashing counter rotating vortices separated from the FC free end. As the FC aspect ratio decreases, the vortex shedding frequency decreases and the vortex formation length increases compared to that of 2-D cylinder. Due to the descending counter-rotating twin-vortex, near the FC free end, regular vortex shedding from the cylinder is suppressed and the vortex formation region is hardly distinguished. Around the center of the wake, the mean velocity for the FC located in atmospheric boundary layer has large velocity deficit compared to that of uniform flow.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.11
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• pp.2651-2657
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• 2014

It can be organized with PVRs and FC-AL for a high-quality TV content-sharing architecture. It is, however, not easy to configure a large community network with the FC-AL since it has a 7-bit address space with supporting up to 127 users. We, therefore, propose a novel scalable FC-AL multiple-loop architecture using shared disks, which does not need to use expensive and load-concentrated switches. In this article, our suggested architecture shows a superb startup delay, such as less than 20msec. In addition, it demonstrates outstanding scalability, such that the number of accomodable users increases almost linearly according to adding loops. Lastly, it reveals exceptional time-shifting hours, that is, which supports more than 140 hours with 1000 users.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.25 no.1
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• pp.1-12
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• 2022

Inflammation plays an important role in the outcome of patients with cystic fibrosis (CF). It may develop due to cystic fibrosis transmembrane conductance regulator protein dysfunction, pancreatic insufficiency, or prolonged pulmonary infection. Fecal calprotectin (FC) has been used as a noninvasive method to detect inflammation. Therefore, the aim of the current meta-analysis was to investigate the relationship between FC and phenotype severity in patients with CF. In this study, searches were conducted in PubMed, Science Direct, Scopus, and Embase databases up to August 2021 using terms such as "cystic fibrosis," "intestine," "calprotectin," and "inflammation." Only articles published in English and human studies were selected. The primary outcome was the level of FC in patients with CF. The secondary outcome was the relationship between FC and clinical severity. Statistical analysis was performed using Comprehensive Meta-Analysis software. Of the initial 303 references, only six articles met the inclusion criteria. The mean (95% confidence interval [CI]) level of FC was 256.5 mg/dL (114.1-398.9). FC levels were significantly associated with pancreatic insufficiency (mean, 243.02; 95% CI, 74.3 to 411.6; p=0.005; I²=0), pulmonary function (r=-0.39; 95% CI, -0.58 to -0.15; p=0.002; I²=60%), body mass index (r=-0.514; 95% CI, 0.26 to 0.69; p<0.001; I²=0%), and Pseudomonas colonization (mean, 174.77; 95% CI, 12.5 to 337.02; p=0.035; I²=71%). While FC is a reliable noninvasive marker for detecting gastrointestinal inflammation, it is also correlated with the severity of the disease in patients with CF.