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Hirschsprung's Disease의 진단과 치료 : 1992년도 현황 -대한소아외과학회 회원대상 선호도 설문조사- (Diagnosis and Treatment of Hirschsprung's Disease in Korea - Current Status of 1992 - -A Survey f or Surgeon's Preference among the Members of the Korean Association of Pediatric Surgeons in 1992-)

  • 유수영;김상윤;김우기;김인구;김재억;박귀원;박우현;박주섭;송영택;오수명;이두선;이명덕;이성철;장수일;정상영;정을삼;정풍만;주종수;최금자;최순옥;최승훈;허영수;황의호
    • Advances in pediatric surgery
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    • 제2권1호
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    • pp.33-41
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    • 1996
  • This report present the result of the national survey of pediatric surgeons' preferences on diagnosis and treatment of Hirschsprung's disease(HD) carried out in 1993. The questionnaires were sent to twenty-seven members of the Korean Association of Pediatric Surgeons (KAPS) working in twenty-four institutions. The questionnaires were designed to determine the individual surgeon's preference for the methods of diagnosis and treatment of the disease. Twenty-three pediatric surgeons from twenty institutions returned completed forms. The total number of patients diagnosed with HD in 1992 was 190 in this group. The estimated incidence of HD was 1/3,900. The most important symptom was delayed meconium passing and the most preferred diagnostic procedure was barium study. Anorectal manometric examination was carried out by 13 pediatric surgeons and 19 confirmed the diagnosis before operation by rectal biopsy, 12 with full-thickness biopsy and 7 with suction. Frozen section biopsy during operation was done by 22 surgeons. Eight surgeons did one stage operation if the age of the patient is suitable. Definitive operation was usually done at the age of 6 to 11 months. The most preferred operation was Duhamel procedure done by 19. Enterocolitis was the most serious complication of HD. Most of patients had normal continence within 6 to 12 months after operation. The follow-up period was less than 6 years in 16 surgeons. The results were presented at the 9th annual meeting of KAPS in June of 1993. This is the first national survey of HD and it can provide guidelines of diagnosis and treatment of Hirschprung's disease even though it is not a detailed study of patient data.

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한국에 있어서 제수문구조물의 설계의 기준을 주기 위한 수문학적 연구(류거, 홍수 편) (The furulamelllal study in order to obtain the hydrological design basis for hydrological structures in Korea (Run ofl estimate and Flood part))

  • 박성우
    • 한국농공학회지
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    • 제8권1호
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    • pp.1011-1034
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    • 1966
  • This thesis is the final report which has long been studied by the author to obtain the design basis for various hydrological constructions with the specific system suitable to the natural environmental conditions in Korea. This report is divided into two parts: one is to estimate runoff volume from watersheds and the other to estimate the peak discharge for a single storm. According to the result of observed runoff record from watersheds, it is known that Kajiyama formula is useful instrument in estimating runoff volume from watersheds in this country. But it has been found that this formula shows us 20-30% less than the actual flow. Therefore, when wihed to bring a better result, the watershed characteristics coefficient in this formula, that is, f-value, should be corrected to 0.5-0.8. As for the method to estimate peak discharge from drainage basin, the author proposes to classify it in two ways; one is small size watershed and the other large size watershed. The maximum -flood discharge rate $Q_p$ and time to peak Pt obtained from the observed record on the small size watershed are compared by various methods and formulas which are based upon the modern hydrological knowledge. But it was fou.d that it. was not a satisfied result. Therefore, the author proposes. tocomputate $Q_p$, to present 4.0-5.0% for the total runoff volume ${\Sigma}Q$.${\Sigma}Q$ is computed under the assumption of 30mm 103s in watershed per day and to change the theoritical total flow volume to one hour dura tion total flow rate when design daily storm is given. Time to peak Pt is derived from three parameters which are u,w,k. These are computed by relationship between total runoff volume (ha-m unit)and $Q_p$. (C.M.S. unit). Finally, the author checked out these results obtained from 51 hydrographs and got a satisfied result. Therefore the author suggested the model of design dimensionless unit-hydrograph. And the author believes that this model will be much available at none runoff record river site. In the large size watersheds in Korea when the maximum discharge occurs, the effective rainfall is two consequtive stormy days. So the loss in watershed was assutned as 6Omm/2days,and the author proposed 3-hour-daration hydrograph flow distribution percentage. This distribution percentage will be sure to form the hydrograph coordinate.

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다이아몬드의 유통구조와 국내감정 현황에 관한 연구 (The Rationalization of Distribution Structure in Diamond Market and Study on Diamond Grading System In Korea)

  • 이상기
    • 유통과학연구
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    • 제14권4호
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    • pp.103-110
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    • 2016
  • Purpose - This study investigates the improvement of rationalization of distribution structure in Korean diamond market. It also explores the international distribution of diamond and how the distribution of Korean diamond market system was improved. This study also for providing the evaluation method in case of purchasing diamond on the consumers. Research Design, Data, and Methodology - The research investigates how international diamond distribution market has been changed since 1933 by De Beers. The international Diamond rough stone has been deregulated in supply and demand by Debeers since July, 2000, therefore, the price maintenance policy of diamond market also has been changed. In the short term, the diamond price in market has been down, whereas, in the long term, the market share of Debeers has affected the high quality of diamond price in world market. Before 1985, both G color and VVS1 clarity were used as the level of percentages in the diamond certificate of authenticity in Korea. But, after 1985, the diamond certificate of authenticity uses Diamond Grading Report. Results - Between the 1970's and 1980's, Debeers had controlled about 80 percentages of international diamond supply market. But, Debeers share in diamond market fell by 60 percentages in 2000's. Debeers supplied 31%(4390 carets) of international diamond supply and 41%(39 billion dollars) in 2003. However, Debeers shares 50% of market shares in the diamond supply market by Alosa in Russia. In Korea, the diamond grading report system has been used since 1985. But, the diamond grading report system has price bubbles and much irrational parts in grading system methods. Conclusions - 4C, the grading system of diamond, is a method for comparing and evaluating diamond objectively. Diamond is graded according to its color, cut, clarity, and carat. The price of diamond is determined based on its each item. Consumers purchase diamond for the purpose of investment and wearing. In terms of investment, it is recommended to purchase diamond with color of D grade, cut with Excellent or Very Good Cut grade, Clarity of FL or IF, and more than 3 carat. As for wearing purpose, it is highly recommended for diamond to have color of F or G grade, cut of Excellent or Very Good Cut, clarity of VS2 or SI1, and more than 1 carat Before 2000, Central Selling Organization(CSO) distributed about 80 percentages rough diamond to world market exclusively by purchase, classification, assessment, and sales. After 2000, Dbeers diamond company looses slowly market shares, while Almosa diamond company etc. in Russia are taking over world market shares more and more. Debeers market shares have been falling over the years, and the international diamond markets are gradually growing by other international diamond companies. But, there is no change in Korean diamond market after 1980's. Korean diamond distribution needs to follow international level of Diamond Grading System. By using different grading systems with different panel members, Korean diamond grading system needs to follow international perfect grading systems to grow diamond markets and maintain within top 10 diamond markets countries.

유물 공간의 종합적 유해생물 관리(Integrated Pest Management)를 위한 실시간(Real-Time) 온습도 모니터링 및 유해 생물 조사 자료의 시각화 (Real-time Monitoring of Temperature and Relative Humidity and Visualization of Pest Survey Data for Integrated Pest Management in Collection Storage Area)

  • 임익균;임승덕;한규성
    • 보존과학회지
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    • 제37권5호
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    • pp.440-450
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    • 2021
  • 수장고 및 전시 공간의 종합적 유해생물 관리를 위하여 실시간 온습도 센서 및 모듈을 이용한 환경 데이터 수집, 실내 부유 진균류 농도 및 곤충 유입 자료의 데이터 시각화를 부여 정림사지 박물관 유물 공간을 대상으로 실시하였다. 실시간 온습도 모니터링 시스템은 30분 단위로 측정 데이터를 수집하였으며 연동 애플리케이션을 통해 측정 데이터를 실시간으로 확인 가능하도록 하였다. 또한 측정된 온습도 데이터가 미리 설정한 범위를 초과하였을 경우, 푸시 알림을 담당자의 단말기로 전송하여 현황 정보를 제공함으로써 상시적 관리 체계를 구축하였다. 이를 통해 8월 중 유물 권장 온도 범위를 초과한 상황의 즉각적인 인지 및 조치가 가능하였다. 수장고 내부 공간에 따른 시기별 부유진균류 농도 데이터를 국립문화재연구소에서 제시한 생물학적 유해환경요인 권고기준(안) 기준으로 범례화하여 시각화한 결과, 수장고 1층과 2층 유물 공간 모두 위험 기준인 80 C.F.U./m3 이하의 부유 진균류 농도가 유지되는 것이 확인되었다. 또한 곤충 유입 조사 결과, 수장고 내부에는 곤충이 포획되지 않았으며, 전시공간의 경우, 딱정그리마, 알락귀뚜라미, 알락꼽등이 등의 곤충이 포획되었다. 이를 바탕으로 구역별 포획 곤충의 개체 밀도에 따른 시각화를 실시한 결과, 곤충의 주요 유입 경로가 외부 출입구 및 화장실 구역임을 확인할 수 있었다.

질병저항성 꿀벌 계통 선발을 위한 청소능력 특성 평가 (Evaluation of Hygienic Ability for the Selection of Disease Resistant Honey Bee (Apis mellifera) Lines)

  • 김혜경;박창규;한국인
    • 생물환경조절학회지
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    • 제30권3호
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    • pp.206-211
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    • 2021
  • 화분매개곤충으로 중요한 산업적 가치를 지닌 꿀벌은 전 세계적으로 병해충에 의한 개체수 감소 현상이 심각한 문제로 제기 되고 있다. 본 논문에서는 이를 타개하기 위하여 질병저항성 꿀벌 계통을 선발하고자 하였으며, 이를 위해 꿀벌 육성 계통별 청소력(hygienic behavior) 평가를 수행하였다. 이는 질병 저항성 계통 선발에 관한 연구로본 연구에서는 5종의 꿀벌 계통과 2종의 교배종 계통에 대한 청소력 평가를 Pin killed brood assay 법에 의해 수행하였다. 그 결과 처리 24 시간 후 죽은 번데기를 제거하거나 개봉하는 능력이 60% 이상으로 청소능력이 낮은 계통(non-hygienic)은 확인되지 않았으며, 반대로 죽은 번데기를 제거하거나 개봉하는 능력이 90%이상인 hygienic 계통은 C, D, E, F, ♀CX♂D 그리고 ♀FX♂D 계통인 것으로 드러났으며, 그 외A 계통은 보통(intermediate)의 청소능력을 가진 것으로 확인 되었다. 이를 통해 본 연구에서는 육성 계통 대부분이 높은 질병저항성 특성을 지니는 것으로 평가되고 있으며, 이러한 결과는 지속적인 질병저항성 꿀벌 계통 선발에 활용할 수 있을 것으로 기대되고 있다.

Development of an Equine Antitoxin by Immunizing the Halla Horse with the Receptor-Binding Domain of Botulinum Neurotoxin Type A1

  • Kim, Na Young;Park, Kyung-eui;Lee, Yong Jin;Kim, Yeong Mun;Hong, Sung Hyun;Son, Won Rak;Hong, Sungyoul;Lee, Saehyung;Ahn, Hye Bin;Yang, Jaehyuk;Seo, Jong-pil;Lim, Yoon-Kyu;Yu, Chi Ho;Hur, Gyeung Haeng;Jeong, Seong Tae;Lee, Hun Seok;Song, Kyoung;Kang, Tae Jin;Shin, Young Kee;Choi, Joon-Seok;Choi, Jun Young
    • Journal of Microbiology and Biotechnology
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    • 제29권7호
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    • pp.1165-1176
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    • 2019
  • Botulinum neurotoxins (BoNTs), produced by Clostridium botulinum, are the most toxic substances known. However, the number of currently approved medical countermeasures for these toxins is very limited. Therefore, studies on therapeutic antitoxins are essential to prepare for toxin-related emergencies. Currently, more than 10,000 Halla horses, a crossbreed between the native Jeju and Thoroughbred horses, are being raised in Jeju Island of Korea. They can be used for equine antitoxin experiments and production of hyperimmune serum against BoNT/A1. Instead of the inactivated BoNT/A1 toxoid, Halla horse was immunized with the receptor-binding domain present in the C-terminus of heavy chain of BoNT/A1 (BoNT/A1-HCR) expressed in Escherichia coli. The anti-BoNT/A1-HCR antibody titer increased rapidly by week 4, and this level was maintained for several weeks after boosting immunization. Notably, $20{\mu}l$ of the week-24 BoNT/A1-HCR(-immunized) equine serum showed an in vitro neutralizing activity of over 8 international units (IU) of a reference equine antitoxin. Furthermore, $20{\mu}l$ of equine serum and $100{\mu}g$ of purified equine $F(ab^{\prime})_2$ showed 100% neutralization of 10,000 $LD_{50}$ in vivo. The results of this study shall contribute towards optimizing antitoxin production for BoNT/A1, which is essential for emergency preparedness and response.

추나요법의 건강보험 및 의료급여 적용에 따른 한방병원에 내원하는 환자군에 대한 통계적 고찰 (The Statistics Study on Patients visiting a Korean Medicine Hospital according to the Application of Chuna Therapy Health Insurance and Medical benefits)

  • 김효준;변다영;김국범;박주언;권용수;유재은;이희원;오민석
    • 대한한의학회지
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    • 제40권3호
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    • pp.188-197
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    • 2019
  • Objectives: The objective of this study is to analyze and observe what kinds of changes in Patients who visited a Korean Medicine Hospital according to the Application of Chuna Therapy Health Insurance and Medical benefits. Methods: In this study we collected data of Patients who first visited the ${\bigcirc}{\bigcirc}{\bigcirc}{\bigcirc}$ Korean Medicine Hospital from March 8 to May 8. we collected data of 1074 Patients who first visited the Daejeon Jaseng Korean Medicine Hospital from March 8 to May 8. Based on the medical charts, Computer order, we analyze and observe statistical data of 1074 patients putting them into six groups. Outcuomes: 1.The increase in the rate of receiving chuna therapy was significant in Group A and Group B(${\rho}<0.05$). 2.The increase in the onset of the disease for more than one year was significant in Group C and Group D(${\rho}<0.05$). 3.The increase in the proportion with disease Corporal was significant in Group E and Group F(${\rho}<0.05$). Conclusions: According to according to the Application of Chuna Therapy Health Insurance and Medical benefits, the number of patients receiving Chuna Therapy increased, and people with old illnesses were more likely to receive Chuna Therapy.

간호대학생의 자기주도 학습능력과 비판적 사고성향이 문제해결능력에 미치는 영향 (Impact of Self-Directed Learning Ability and Critical Thinking Disposition on Problem Solving Ability in Nursing Students)

  • 류현숙;김지영
    • 한국응용과학기술학회지
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    • 제39권1호
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    • pp.42-51
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    • 2022
  • 본 연구는 간호대학생의 문제해결능력, 자기주도 학습능력, 비판적 사고성향 간의 관련성을 파악하고 문제해결능력에 대한 영향요인을 확인하기 위한 서술적 조사연구이다. 연구대상자는 G도와 C도에 소재하는 2개 대학 간호대학생 226명이었고 구조화된 설문지를 이용하여 조사하였다. 수집된 자료는 기술 통계, t-test, ANOVA, Pearson's 상관관계 분석 및 다중회귀분석을 이용하여 분석하였다. 간호대학생의 문제해결능력의 영향요인을 확인하기 위해 다중회귀분석 결과, 비판적 사고성향(β= .490, p< .001)과 자기주도 학습능력(β= .355, p< .001)이 영향요인으로 나타났다. 회귀모형의 적합도에 대한 F 통계량은 183.523(p< .001)으로 유의하였고, 설명력은 61.9%인 것으로 나타났다. 따라서 간호대학생의 문제해결능력 향상을 위해서는 비판적 사고성향과 자기주도 학습능력이 향상될 수 있도록 다양한 교수학습방법을 접목해야 할 것이다. 본 연구는 간호대학생의 문제해결능력을 향상시키기 위한 교육프로그램을 개발하는데 기초자료로 유용하게 활용될 것이다.

Along and across-wind vibration control of shear wall-frame buildings with flexible base by using passive dynamic absorbers

  • Ivan F. Huergo;Hugo Hernandez-Barrios;Roberto Gomez-Martinez
    • Wind and Structures
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    • 제38권1호
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    • pp.15-42
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    • 2024
  • A flexible-base coupled-two-beam (CTB) discrete model with equivalent tuned mass dampers is used to assess the effect of soil-structure interaction (SSI) and different types of lateral resisting systems on the design of passive dynamic absorbers (PDAs) under the action of along-wind and across-wind loads due to vortex shedding. A total of five different PDAs are considered in this study: (1) tuned mass damper (TMD), (2) circular tuned sloshing damper (C-TSD), (3) rectangular tuned sloshing damper (R-TSD), (4) two-way liquid damper (TWLD) and (5) pendulum tuned mass damper (PTMD). By modifying the non-dimensional lateral stiffness ratio, the CTB model can consider lateral deformations varying from those of a flexural cantilever beam to those of a shear cantilever beam. The Monte Carlo simulation method was used to generate along-wind and across-wind loads correlated along the height of a real shear wall-frame building, which has similar fundamental periods of vibration and different modes of lateral deformation in the xz and yz planes, respectively. Ambient vibration tests were conducted on the building to identify its real lateral behavior and thus choose the most suitable parameters for the CTB model. Both alongwind and across-wind responses of the 144-meter-tall building were computed considering four soil types (hard rock, dense soil, stiff soil and soft soil) and a single PDA on its top, that is, 96 time-history analyses were carried out to assess the effect of SSI and lateral resisting system on the PDAs design. Based on the parametric analyses, the response significantly increases as the soil flexibility increases for both type of lateral wind loads, particularly for flexural-type deformations. The results show a great effectiveness of PDAs in controlling across-wind peak displacements and both along-wind and across-wind RMS accelerations, on the contrary, PDAs were ineffective in controlling along-wind peak displacements on all soil types and different kind of lateral deformation. Generally speaking, the maximum possible value of the PDA mass efficiency index increases as the soil flexibility increases, on the contrary, it decreases as the non-dimensional lateral stiffness ratio of the building increases; therefore, there is a significant increase of the vibration control effectiveness of PDAs for lateral flexural-type deformations on soft soils.

성산딕카이트광상에서의 백악기산성마그마티즘에 관련된 열수변질작용 ; 광상형성온도의 측정 및 열수용액의 aNa+/aK+ (Hydrothermal Alteration Related to Cretaceous Felsic Magmatism in the Seongsan Dickite Deposits, Korea; Estimation of Ore - Forming Temperature and aNa+/aK+ Ratio of the Hydrothermal Fluid)

  • 김인준
    • 자원환경지질
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    • 제25권3호
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    • pp.259-273
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    • 1992
  • 성산광산은 한반도의 남서부에 위치하는 큰 딕카이트광상 중에 하나이다. 광석광물로는 주로 딕카이트와 석영이며, 소량의 명반석, 카올리나이트 및 견운모가산출된다. 성산광상의 주변지질은 주로 백악기의 산성 화산암류로 구성된다. 연구지역에서 이러한 암석들은 동서방향의 축을 갖고 동쪽으로 경사지는 향사구조를 갖는다. 산성 화산암류는 심한 열수변질작용을 받고 있다. 이러한 암석들은 중심부로부터 바깥쪽으로 딕카이트, 딕카이트-석영, 석영, 견운모, 알바이트 및 녹니석대로 구분된다. 변질암의 이러한 누대배열은 주변암 (용결응회암과 유문암의 상부)이 산성열수에 의한 변질작용으로 생성되었다. 그것은 황화수소를 함유한 용액과 초기 가스, 그리고 다른 것들이 지표 가까이에서 산화되었고, 황산열수용액에 의해 형성되어졌음을 시사한다. 변질암의 광물학적, 화학적 변화에 대하여는 여러가지 방법으로 검토하였고, 특히, 56개의 변질암에 대한 화학조성은 습식분석과 XRF로써 분석하였다. 이러한 분석자료들을 기초로 하여 고창한 결과 거의 모든 원소가 원암으로부터 이동되었다고 사료된다. 광상의 형성온도는 석영대로부터 얻은 시료의 유체포유물 연구로부터 200 이상임이 판명되었다. 변질대의 광물조성과 암석의 화학 성분으로 보아 성산광상을 형성한 열수용액은 $m_{K^+}=0.003$, $m_{Na^+}=0.097$, $m_{SiO_2(aq.)}=0.008$ 및 pH=5.0으로 나타났다.

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