• 한국의학물리학회지:의학물리
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• 제32권4호
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• pp.179-184
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• 2021

This study aimed to determine the optimal thickness of the active layer and scan mode for a flexible radiochromic film (F-RCF) based on the active lithium salt of pentacosa-10,12-diynoic acid (LiPCDA). F-RCFs of 90, 120, 140, and 170-㎛ thickness were fabricated using LiPCDA. Several pieces of the F-RCFs were exposed to doses ranging from 0 to 3 Gy. Transmission and reflection modes were used to scan the irradiated F-RCFs. Their dose-response curves were obtained using a second-order polynomial equation. Their sensitivity was evaluated for both scanning modes, and the uniformity of the batch was also examined. For both the transmission and reflection modes, the sensitivity increased as the film thickness increased. For the reflection mode, the dose response increased dramatically under 1 Gy. The value of the net optical density varied rapidly as the thickness of the film increased. However, the dose-response curves showed a supralinear-curve relationship at doses greater than 2 Gy. The sensitivity of the reflection scan at doses greater than 2 Gy was higher than that of the reflection scan within 0-2 Gy. The sensitivity steadily decreased with increasing doses, and the sensitivity of the two modes was within 0.1 to 0.2 at 2 Gy and was saturated beyond that. For the transmission scan, the sensitivity was approximately 0.2 at 3 Gy. For the intra-batch test result, the maximum net optical density difference of the intra-batch was 5.5% at 2 Gy and 7.4% at 0.2 Gy in the transmission and reflection scans, respectively. In the low-dose range, film thickness of more than 120-㎛ was proper in the transmission mode. In contrast, the transmission mode showed a better result compared to the reflection mode. Therefore, the proper scan mode should be selected according to the dose range.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2000년도 하계학술대회 논문집
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• pp.934-941
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• 2000

We measured the electron transport coefficients, the electron drift velocity W and the longitudinal diffusion coefficient $D_{L}$ in the 0.526% and 5.05% $C_{3}F_{8}$-Ar mixtures over the E/N range from 0.01 Td to 100 Td by the double shutter drift tube, and compared the measured results by Hunter et al. with those. We determined the inelastic collision cross sections for the $C_{3}F_{8}$ molecule by the comparison of the present measurements and the calculation of electron transport coefficients in the $C_{3}F_{8}$-Ar mixtures by using a multi-term Boltzmann equation analysis.

• 대한본초학회지
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• 제31권3호
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• pp.71-75
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• 2016

Objectives : Mori Ramulus is a young branch of Morus alba Linne, which has been used as traditional medicines for antidiarrhea, antibacteria, and antihypertension in Korea. With the basis on these medicinal activities, it is registered at the Korean Herbal Pharmacopoeia. The standard for quality control in use, however, is not yet validated.Methods : We experiment on heavy metals test, TLC, loss on drying, ash, acid-insoluble ash, contents of ethanolsoluble extracts and contents of oxyresveratrol by using the 15 samples of Mori Ramulus which are collected domestically. We tested items according to the General Test, processes and apparatus, Crude Drugs Test of KP(2011).Results : Purity test(Heavy metals) showed contents for Pb, As, Hg, and Cd range of 0.1~1.1 ppm, 0.0~0.2 ppm, 0.00~0.01 ppm, and 0.00~0.02 ppm. Identification test(Thin layer chromatography) was on comparing with morucine standard solution in R_f value, all samples showed morucine spot (dark blue, R_f : 0.3) as same as R_f value of morucine-standard solution. Loss on drying was ranged from 5.1 to 8.9 %, ash and acid-insoluble ash were between the range 3.0~6.3% and 0.3~0.8%. Contents of ethanol-soluble extracts was ranged from 6.2 to 12.0%. Content of oxyresveratrol was ranged from 0.01 to 0.16 % based on the oxyresveratrol standard curve.Conclusions : We sincerely hope that this study will be contributed to the standardization and quality control of Korean herbal medicines.

• 말소리와 음성과학
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• 제1권1호
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• pp.99-107
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• 2009

In view of the hypothesis that the effects of Parkinson disease on voice production can be detected before pharmacological intervention, the voice differences of patients with Idiopathic Parkinson's disease and a healthy aging group were diagnostically analyzed with the long term object of establishing, for clinical purposes, early disease-progression biomarkers. Fifteen patients with Idopathic Parkinson's disease (prior to pharmacological intervention) and a healthy control group of 15 were selected and every voice was recorded three times using praat (ver. 5022) with a headset mic. Relevant parameters - acoustic measure of /a/ phonation, F0 related parameters, MPT related parameters, articulatory ratio, VOT - were then analyzed by MANOVA. Significant differences were found in the F0 related (low F0, high F0, F0 range) and MPT related parameters. There were also significant differences in acoustic measurements (intensity, shimmer, HNR, jitter), AMR (/$t{\Lambda}$/,/$k{\Lambda}$/) and VOT (/ta/), The findings indicated that the voice production of patients with Idiopathic Parkinson's disease have normal pitch but bad quality. In particular, with slow articulatory ratios and VOT values, the tongue tip functioning of patients was lower than for the healthy group.

• 한국산학기술학회논문지
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• 제16권5호
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• pp.3051-3059
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• 2015

본 연구에서는 가습소자 개발을 목적으로 절곡형상이 전열판의 성능에 미치는 영향을 수치해석적으로 검토하였다. 수치해석은 절곡각을 변화시키며 ($0^{\circ}/0^{\circ}$에서 $60^{\circ}/60^{\circ}$사이의 등각도와 $15^{\circ}/0^{\circ}$에서 $15^{\circ}/60^{\circ}$사이의 엇각도) 수행되었다. 해석 결과 j와 f 인자 모두 절곡각이 증가할수록 증가하였다. 특히 f 인자는 절곡각이 큰 영역에서 급격히 증가하였다. 엇각도 전열판의 j, f 인자와 두 각을 평균내어 구한 등각도 전열판의 j, f 인자는 거의 같은 값을 나타내었다. 한편 동일 소비동력 대비 열전달량을 나타내는 $j/f^{1/3}$의 경우 $15^{\circ}/15^{\circ}$에서 가장 크게 나타났다. 기존 상관식은 본 수치해석 결과를 과대 또는 과소예측하였다.

• 보건의료산업학회지
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• 제13권2호
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• pp.121-133
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• 2019

Objectives: The purpose of this study was to determine the effectiveness of hand acupressure in relieving shoulder pain among male manufacturing workers. Methods: A nonequivalent control group was employed using a nonsynchronized design. Data were collected from two manufacturing plants located in metropolitan area U. The data were analyzed with a ${\chi}^2$-test and an independent t-test to perform a homogeneity test, and with repeated ANOVA measures to perform an hypothesis test using the SPSS 21.0 program. Results: Hypothesis 1 that "the experimental group provided with hand moxibustion would score lower for low shoulder pain than the control group" was supported (F=306.05, p<.001). Hypothesis 2, that "the experimental group provided with hand moxibustion would have a wider range of motion than the control group" was also supported with increased flexion(F=7.73, p<.001), extension(F=7.89, p=.001), abduction(F=21.23, p<.001), and horizontal abduction(F=20.89, p=.028). Hypothesis 3, that "the experimental group provided with hand moxibustion would score lower for quality of sleep than the control group" was not supported (F=56.10, p=.091). Conclusions: Hand moxibustion is effective in relieving shoulder pain for male manufacturing workers, in relieving low shoulder pain and increasing the range of motion.

• International Journal of Industrial Entomology and Biomaterials
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• 제22권2호
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• pp.83-93
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• 2011

Biochemical and enzymatic characterization for extracellular protease isolated from Cordyceps militaris cultivated on rice bran medium was investigated. C militaris produced proteolytic enzymes from 10 days after inoculation, maximum enzyme production was found at 25 days. The optimum temperature and pH of proteases production was at $25^{\circ}C$ and pH 7.0, respectively. The protease activity was observed in the four peaks (Pro-I, Pro-II, Pro-III, and Pro-IV) separated through Sephadex G-100 column chromatography. The separated protease was optimally active at $25^{\circ}C$. Optimum pH of the protease was between 7 and 8. Enzyme was also stable over at $30-80^{\circ}C$. The enzyme was highly stable in a pH range of 4-9. Protease activity was found to be slightly decreased by the addition of $Mg^{2+}$, $Mn^{2+}$, $Zn^{2+}$, $Fe^{2+}$ and $Cu^{2+}$, whereas inhibited by the addition of $Ca^{2+}$ and $Co^{2+}$ Protease activity was inhibited by protease inhibitor PMSF. On the other hand, the partially purified protease was investigated on proteolytic protease activity by zymogram gel electrophoresis using three substances (casein, gelatin and fibrin). Four active bands (F-I, FII, F-III, and F-IV) of fibrin degradation were revealed on fibrin zymogram gels. Both of F-II and FIII showed caseinolytic, fibrinolytic and gelatinolytic activities in three gels. Thermostability, pH stability, and pH-thermostability of the enzyme determined the residual fibrinolytic activity also displayed on fibrin zymogram gel. The only one enzyme (F-II) displayed over a broad range of temperature at $30-90^{\circ}C$. The FII displayed fibrinolytic activity in the pH range 3-5, but was inactivated in the range of pH 6-11. The F-I and F-III showed enzyme activity in the pH range of 6-11. In the pH-thermostability, the F-II only kept fibrinolytic activity after heating at $100^{\circ}C$ for 10, 20 and 30 min at pH 3 and pH 7, respectively. On the other hand, the F-II was retained activity until heating for 10 min under pH 11 condition. By using fibrin zymogram gel electrophoresis, extracellular fibrinolytic enzyme F-II from C. militaris showed unusual thermostable under acid and neutral conditions.

• 대한기계학회논문집B
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• 제26권4호
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• pp.515-523
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• 2002

Effects of rotary oscillation on unsteady laminar flow past a circular cylinder have been investigated in this study. Numerical simulations are performed for the flow at Re=100 in the range of 0.2<$\Omega$<2.5 and 0.02<$St_f$<0.8, where $\Omega$ and $St_f$ are, respectively, the maximum rotation velocity and rotation frequency normalized by the free-stream velocity and cylinder diameter. Results show that rotary oscillation has significant effects on the flow. When the rotation frequency is near the natural vortex-shedding frequency, lock-on occurs and the lock-on frequency range becomes wider as the rotation velocity increases. In a certain range of the rotation frequency and velocity, modulations in the velocity, lift and drag signals occur and this modulation frequency is expressed as a linear combination of the rotation frequency and vortex-shedding frequency. The mean drag and amplitude of the lift fluctuations show local minima near the boundary between the lock-on non and lock-on regions.

• Macromolecular Research
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• 제9권4호
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• pp.228-237
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• 2001

The evolution of conformational constraints in bisphenol-A polycarbonate (BAPC) upon quiescent bulk crystallization was quantitatively analyzed from calorimetric study employing a rigid amorphous fraction (RAF) as an indicator of the level of conformational constraints. From the correlation between corrected crystallinity (X$\sub$c/) and total rigid fraction (f$\sub$r/), it was found that, regardless of molar mass distribution and thermal treatment conditions, semicrystalline BAPC always exhibits greater f$\sub$r/ than X$\sub$c/ maintaining a quantitative relationship of f$\sub$r/〓2X$\sub$c/ in the range of 0.0 $\sub$c/< 0.4. This directly indicates the evolution of approximately the same amount of RAF as X$\sub$c/, (i.e., RAF〓X$\sub$c/) upon bulk crystallization of BAPC. It was also found that T$\sub$g/ per se and T$\sub$g/ broadening enhance as RAF increases, and there appears to be a critical level of RAF (>0.2) needed to initiate significant changes in both quantities.

• 여성건강간호학회지
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• 제2권2호
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• pp.270-283
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• 1996

This study was done for the purpose of analyzing the relationship between menopausal symptoms and depression. Data were collected by a questionnaire from November 28 to December 30, 1995. The subjects were 134 women between 40-61 years of age. The instruments used for this study were The Menopausal symptom scale by Neugartom and Depression scale by Zung. The results of the study were as follows. 1. Mean score of menopausal symptoms was 1.59. Mean score orders of experienced symptoms were "Rack pain and joint pain"(2.02), "General weakness"(1.98), "Nervousness"(1.96). The most serious menopausal symptom was psychosomatic symptom.(1.88) Total score orders of experienced symptoms was 27.9 and over 90.3% of women complained menopausal symptom. 2. Mean score orders of depression was 39.13. It was normal range of depression. 85.1% of the women were normal range of depression and 14.2% of women mild depression. 3. The relationship between menopausal symptoms and depression was statistically significant(r=0.5307, p=0.000). When the relationship among three dimensions of menopausal symptoms were explored the psychosomatic symptom(r=0.4090, P=0.000), Physical symptom(r=0.319, P=0.000), Physical symptom(r=0.319, P=0.000) were statistically significant. 4. General characteristic variables were significantly related to the level of menopausal symptoms as follows ; environment of living(F=2.89, p=0.038), religion(F=4.18, P=0.007), times of birth(F=2.66, p=0.043). The analysis of this study have implication for management of middle aged women's health, to solve the nursing problems, and to prevent and relieve climacteric symptoms.