• The Korean Journal of Ceramics
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• v.4 no.4
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• pp.372-376
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• 1998

Using calcium-phosphate-powder targets with the Ca/P ratios of 1.0-1.67, hydroxyapatite ($Ca_{10}(PO_4)_6(OH)_2$, HAp) thin films with 4-7㎛ thickness were prepared on titanium metal plates by r.f. magnetron sputtering, followed an annealing at $200^{\circ}C$ for 24 hr under a high water vapor pressure using an autoclave. All the specimens were systematically characterized by XRD, FT-IR, SEM and EDS analyses. The post-annealed films were confirmed to be a nonstoichiometric oxyhydroxyapatite by XRD and FT-IR measurements.

• Proceedings of the Korean Nuclear Society Conference
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• 2004.10a
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• pp.1253-1254
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• 2004

• Journal of Music and Human Behavior
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• v.13 no.2
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• pp.67-83
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• 2016

This study investigated the tonal characteristics in Korean emotion words by analyzing the pitch patterns transformed from word utterance. Participants were 30 women, ages 19-23. Each participant was instructed to talk about their emotional experiences using 4-syllable target words. A total of 180 utterances were analyzed in terms of the frequency of each syllable using the Praat. The data were transformed into meantones based on the semi-tone scale. When emotion words were used in the middle of a sentence, the pitch pattern was transformed to A3-A3-G3-G3 for '즐거워서(joyful)', C4-D4-B3-A3 for '행복해서(happy)', G3-A3-G3-G3 for '억울해서(resentful)', A3-A3-G3-A3 for '불안해서(anxious)', and C4-C4-A3-G3 for '침울해서(frustrated)'. When the emotion words were used at the end of a sentence, the pitch pattern was transformed to G4-G4-F4-F4 for '즐거워요(joyful)', D4-D4-A3-G3 for '행복해요(happy)', G3-G3-G3-A3 and F3-G3-E3-D3 for '억울해요(resentful)', A3-G3-F3-F3 for '불안해요(anxious)', and A3-A3-F3-F3 for '침울해요(frustrated)'. These results indicate the differences in pitch patterns depending on the conveyed emotions and the position of words in a sentence. This study presents the baseline data on the tonal characteristics of emotion words, thereby suggesting how pitch patterns could be utilized when creating a melody during songwriting for emotional expression.

• Journal of the Korean Ceramic Society
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• v.39 no.8
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• pp.742-749
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• 2002

The PZT thin films werre deposited on Pt/Ti/$SiO_2$/Si substrate by R. F. magnetron sputtering with $Pb_{1.1}Zr_{0.53}Ti_{0.47}O_3$ target. When interlayers(PbO, $TiO_2$, PbO/$TiO_2$) were inserted between PZT and Pt, the crystallization of the PZT thin films was considerably improved and the processing temperature was lowered. Compared to the pure PZT thin films, dielectric constant, dielectric loss and polarization properties of PZT thin films with interlayers were considerably improved. From XPS depth profile analysis, it was confirmed that PZT thin films and interlayers existed independently. In particular, PZT thin films deposited on interlayer(PbO/$TiO_2$) showed the best dielectric property (${\varepsilon}_r$=414.94, tan${\delta}$=0.0241, Pr=22${\mu}C/cm^2$).

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.1833-1840
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• 2013

Metastasis is one of the hallmarks of malignant neoplasms and is the leading cause of death in many cancer patients. A major challenge in cancer treatment is to find better ways to specifically target tumor metastasis. In this study, the anti-metastatic potential of the methanolic extract of Rhizophora apiculata (R.apiculata) was evaluated using the B16F-10 melanoma induced lung metastasis model in C57BL/6 mice. Metastasis was induced in C57BL/6 mice by injecting highly metastatic B16F-10 melanoma cells through the lateral tail vein. Simultaneous treatment with R.apiculata extract (10 mg/kg b.wt (intraperitoneal) significantly (p<0.01) inhibited pulmonary tumor nodule formation (41.1 %) and also increased the life span (survival rate) 107.3 % of metastatic tumor bearing animals. The administration of R.apiculata extract significantly (p<0.01) reduced biochemical parameters such as lung collagen hydroxyproline, hexosamine, uronic acid content, serum nitric oxide (NO), ${\gamma}$-glutamyl transpeptidase (GGT) and sialic acid levels when compared to metastasis controls. These results correlated with lung histopathology analysis of R.apiculata extract treated mice showing reduction in lung metastasis and tumor masses. Taken together, our findings support that R.apiculata extract could be used as a potential anti-metastasis agent against lung cancer.

• Proceedings of the Korean Society of Computational and Applied Mathematics Conference
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• 2003.09a
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• pp.6-6
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• 2003

In this work we consider the mathematical formulation and numerical resolution of the linear feedback control problem for Boussinesq equations. The controlled Boussinesq equations is given by $$\frac{{\partial}u}{{\partial}t}-{\nu}{\Delta}u+(u{\cdot}{\nabla}u+{\nabla}p={\beta}{\theta}g+f+F\;\;in\;(0,\;T){\times}\;{\Omega}$$, $${\nabla}{\cdot}u=0\;\;in\;(0,\;T){\times}{\Omega}$$, $$u|_{{\partial}{\Omega}=0,\;u(0,x)=\;u_0(x)$$ $$\frac{{\partial}{\theta}}{{\partial}t}-k{\Delta}{\theta}+(u{\cdot}){\theta}={\tau}+T,\;\;in(0,\;T){\times}{\Omega}$$ $${\theta}|_{{\partial}{\Omega}=0,\;\;{\theta}(0,X)={\theta}_0(X)$$, where $\Omega$ is a bounded open set in $R^{n}$, n=2 or 3 with a $C^{\infty}$ boundary ${\partial}{\Omega}$. The control is achieved by means of a linear feedback law relating the body forces to the velocity and temperature field, i.e., $$f=-{\gamma}_1(u-U),\;\;{\tau}=-{\gamma}_2({\theta}-{\Theta}}$$ where (U,$\Theta$) are target velocity and temperature. We show that the unsteady solutions to Boussinesq equations are stabilizable by internal controllers with exponential decaying property. In order to compute (approximations to) solution, semi discrete-in-time and full space-time discrete approximations are also studied. We prove that the difference between the solution of the discrete problem and the target solution decay to zero exponentially for sufficiently small time step.

• Animal cells and systems
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• v.16 no.4
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• pp.280-288
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• 2012

Targeted degradation of proteins through ubiquitin-mediated proteolysis is an important control mechanism in various cellular processes. The process of ubiquitin conjugation is achieved by three enzyme complexes, among which the ubiquitin ligase complex (E3) is in charge of substrate specificity. The SCF (SKP1-CUL1-F-box) family portrays the largest and the most characterized member of the E3 ligases. For each SCF complex, the ubiquitination target is recognized by the F-box protein subunit, which interacts with the substrate through a unique C-terminal domain. We have characterized a novel F-box protein CFL-1 that represents a single LRR-type F-box (FBXL) in the Caenorhabditis elegans genome. CFL-1 is highly homologous to FBXL20 and FBXL2 of mammals, which are known to regulate synaptic vesicle release and cell cycle, respectively. A green fluorescence protein (GFP)-reporter gene fused to the cfl-1 promoter showed restricted expression around the amphid and the anus. Modulation of CFL-1 activity by RNAi affected the time interval between defecations. RNAi-treated worms also exhibited reduced tendency to form dauer when exposed to daumone. The potential involvement of CFL-1 in the control of defecation and pheromone response adds to the ever expanding list of cellular processes controlled by ubiquitin-mediated proteolysis in C. elegans. We suggest that CFL-1, as a single LRR-type F-box protein in C. elegans, may portray a prototype gene exerting diverse functions that are allocated among multiple FBXLs in higher organisms.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.49 no.4
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• pp.432-439
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• 2013

This study was performed to assess the current stock condition of elkhorn sculpin along the Uljin area in the East Sea of Korea. To assess the state of the stock, yield-per-recruit (YPR) and spawning biomass-perrecruit (SBPR) analyses were performed. Estimates of $F_{max}$ and $F_{0.1}$ were 2.10/year and 0.48/year, respectively, and those of $F_{35%}$ and $F_{40%}$ were 0.66/year and 0.54/year, respectively. Current fishing mortality was estimated at 0.63/year and the current age at first capture was 2.41years. $F_{40%}$ was set as the target reference point of the stock. SBPR at $F_{40%}$ and current SBPR were estimated to be 41.85g and 37.77g, respectively. Estimated FOTY which is the fishing mortality for the overfished threshold yield was 0.49/year. The ratio of SBPR/$SBPR_{MSY}$ was calculated as 0.90 and that of $F/F_{OTY}$ was 1.05. The ratio of $t_c/t_{c\;opt}$ was calculated as 1.15 and that of $F/F_{OTY}$ was 1.17. Therefore, the current stock condition of elkhorn sculpin along the Uljin area of Korea has not been overfished, however, it indicates that a light overfishing is going on this stock.

• Journal of Environmental Science International
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• v.23 no.8
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• pp.1437-1446
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• 2014

This study, the urban energy used office building green roof type composition of the target by analyze building energy reductions. Green roof is total 6 types(type A~F) were selected, EnergyPlus the energy simulation programs were used. Top floor of green roof types evaluation, the reduction of the cooling peak load type E(1.26%), type D(1.30%), type C(1.37%), type B(1.45%), type F(1.49%), and heating peak load is type D(1.32%), type E(1.40%), type C(1.47%), type F(1.69%), type B(2.13%) order. Annual cooling load of heating load is reduced more than about 1% effect. The heating load reduction ratio for a maximum of 9% respectively. Cooling peak load of the building energy performance evaluation of type F > type B > type C > type D > type E in the order and in the case of peak loads heating type B > type F > type D > type E>type C order. Annual total energy use reduction of 1.07 to 1.22% and earn, type B in the best good. In primary energy use reductions in the presence of a green roof were in the 4249~4876 kWh/yr. Annual $CO_2$ emissions reductions of unapplied type A were analyzed on average 469.78 kg.

• 한국전산유체공학회:학술대회논문집
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• 2008.03b
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• pp.205-208
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• 2008

The wind load on building surface is numerically investigated. The geometry of target building is a square cross section and aspect ratio (height (H) to width (d)) is 6. On building surface, the pressure was measured, compared to obtained value from numerical simulation. The numerical simulations were done using URANS with three different turbulence models such as v2-f model, k-${\omega}$model, and k-${\varepsilon}$ model, respectively. The v2-f model showed the best agreement with experimental data in simulating mean pressure coefficients on front, rear and side surface. But unsteady characteristics of pressure history measured on surface is shown a discrepancy between experiment and numerical simulation.