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Diagnostic Role of Serum Free-to-Total Prostate Specific Antigen (PSA) Ratio in Prostate Cancer with Serum Total Concentration of PSA below 4 ng/mL

  • Chang, Chih-Chun;Lee, Yi-Chen;Tsai, Huang-Wen;Yii, Shyi-Chun;Yen, Tzung-Hai;Chu, Fang-Yeh
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.13
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    • pp.5261-5264
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    • 2015
  • Purpose: To examine the effectiveness of serum free-to-total prostate specific antigen ratio (%fPSA) for the detection of prostate cancer (PCa) in men with different serum total PSA (tPSA) categories. Materials and Methods: From January 2010 to December 2013, a total of 225 patients with lower urinary tract symptoms (LUTS) underwent tPSA and %fPSA measurements. Histological examination with calculation of Gleason score and whole body bone scans were performed in identified cases of PCa. Results: PCa was diagnosed in 44 (19.6%) patients and the remaining 181 patients had benign prostate disease. PCa was detected in 5 (23.8%), 13 (8.7%) and 26 (47.3%) cases with tPSA level ranges ${\leq}4ng/ml$, 4 to 10 ng/ml and >10 ng/ml, respectively. The average Gleason score was $7.2{\pm}0.2$. Some 6 (13.6%) out of 44 PCa patients had bone metastases. The sensitivity was 80% and specificity was 81.3% at the cut-off %fPSA of 15% in PCa patients with a tPSA level below 4 ng/mL. A lower %fPSA was associated with PCa patients with Gleason score ${\geq}7$ than those with Gleason score ${\leq}6$ ($11.7{\pm}0.98$ vs. $16.5{\pm}2.25%$, P=0.029). No obvious relation of %fPSA to the incidence of bone metastasis was apparent in this study. Conclusions: The clinical application of %fPSA could help to discriminate PCa from benign prostate disease in men with a tPSA concentration below 4 ng/mL.

A Study on Health Promoting Behavior In Post-Mastectomy Patients (유방절제술을 받은 여성의 건강증진행위에 관한 연구)

  • Kim, Hyun Ju;So, Hyang Sook
    • Korean Journal of Adult Nursing
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    • v.13 no.1
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    • pp.82-95
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    • 2001
  • The purpose of this study was to examine the relationship among perceived health status, self-esteem, self-efficacy and health promoting behavior, and to determine the predictors of health promoting behavior in post-mastectomy patients. The study, a descriptive correlational study, was done with structural questionnaires. A total of 51 post-mastectomy subjects from C university hospital in Kwang-ju, South Korea completed mail-in self-reporting questionnaires during a three month period from March to June, 1999. The data were collected using Lawstone's(1982) perceived health status scale, Rosenberg's(1965) self-esteem scale, the modified self-efficacy scale(Shere et al, 1982), and the modified health promoting lifestyle profile (Walker et al, 1987). The data obtained were analyzed according to percentage, mean and standard deviation, principal component analysis, varimax rotation, t-test, ANOVA, Pearson's correlation, and stepwise multiple regression. The results were as follows: 1. The health promoting behavior measurement resulted in six factors. Each factor was labelled as follows: self-actualization, nutrition, stress management, exercise, health responsibility and interpersonal support. The total percent of variance explained by the six factors was 58.4%. 2. The mean score of health promoting behavior was 85.92(range 58~117). The scores of six factor were nutrition 3.20, self-actualization 2.59, stress management 2.58, interpersonal support 2.58, health responsibility 2.49, and exercise 2.34 on a four point scale. 3. When the score of health promoting behavior factors were compared by general characteristics. Factor I: self-actualization, differed significantly by the frequency of pregnancy (F=3.06, p=.037). Factor II: nutrition differed significantly by drinking experience(t=-2.26, p=.028) and the pre- or post stage of menopause(F=2.69, p=078). FactorIII: stress management differed significantly depending on regularity of mensturation(t=-2.12, p= .042). FactorIV: exercise differed significantly by type of religion (F=2.49, p=.072), marital status(F=5.03, p=.010), and feeding type (F=2.64, p=.036). Factor V: health responsibility differed significantly by regularity of mensturation(t=2.18, p=.037). 4. The total health promoting behavior score was significantly related to self-esteem and perceived health status(r=.610, p.006; r= .378, p=.006). The score of selfactualization also corresponded with selfesteem and perceived health status(r=.556, p=.001; r=.343, p=.013). 5. The predictor to explain the score of health promoting behavior was self-esteem, which accounted for 37.1% of the total variance. The predictor to explain the score of self-actualization was self-esteem, which accounted for 30.9% of the total variance. The score of nutrition was primarily affected by both premenopause and drinking experience, which accounted for 13.1% and 9.5% respectively. Finally, the score of exercise was dictated by marriage, Buddhism, no experience of breast feeding, which accounted for 17%, 9.8%, & 5.2% respectively. In conclusion, self-esteem is the main predictor for health promoting behavior in post-mastectomy women. These findings suggest a need for nursing strategies which promote self-esteem in such patients.

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Relationships among School Children′s Internet Addiction, Family Environment and School Adjustment (학령기 아동의 인터넷 중독과 가정환경 및 학교생활 적응과의 관계 - 초등학교 5, 6학년 아동들을 중심으로 -)

  • Kim, Ji-Young;Ryu, Hyun-Sook
    • Child Health Nursing Research
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    • v.9 no.2
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    • pp.198-205
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    • 2003
  • Purpose: The purpose of this study is to investigate the degree of school children's internet addiction and to explicit the relationship among the internet addiction, family environment and school adjustment. Method: The subjects of the study were 640 students from 5th and 6th year children of five elementary schools in G city. The data were analyzed by SAS program with frequency, percentage, means, standard deviation, χ² -test, ANOVA and Pearson's Correlation Coefficient. Result: In the degree of the internet addiction were 10.0% of addiction group, 58.0% of intermediate group, and 32.0% of nonaddiction group. There were significant differences in family environment score(F=25.09, p=.0001) and school adjustment score(F=34.46, p=.0001) regarding internet addiction degree. The relationship among internet addiction score, family environment score and school adjustment score revealed a significant inverse correlation(r=-0.32, p=.0001, r=-0.35, p=.0001). And the relationship between family environment score and school adjustment score revealed a significant correlation(r=0.52, p=.0001). Conclusion: The degree of school children's internet addiction has been found to be very high and correlated to the family environment and school adjustment. Therefore, programs should be developed in order to improve this situation.

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The relation between phonetic differences of Korean learners' production of English vowels, pronunciation intelligibility and speaking proficiency test scores (한국인 학습자 영어 모음 발화의 음성학적 차이와 발음 이해도, 말하기 점수와의 관계)

  • Kim, Ji-Eun
    • Phonetics and Speech Sciences
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    • v.9 no.2
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    • pp.1-7
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    • 2017
  • The purpose of this study is to investigate the relations between phonetic differences among Korean learners' production of English front vowels, pronunciation intelligibility and speaking proficiency test score. To do so, thirty Korean university students were asked (1) to read English text book paragraphs and (2) describe a picture. Two English native raters and one Korean rater evaluated Korean subjects' English pronunciation intelligibility and speaking. In addition, subjects' English vowel productions were acoustically analyzed(F0, F1, F2, vowel duration, intensity). The results of the study show that the vowel quality and pitch of the unstressed vowels and lax vowel are related to the pronunciation intelligibility. In addition, the scores of pronunciation intelligibility and speaking are highly related.

A Study of the Effectiveness of Basic CPR (Cardiopulmonary Resuscitation) Education of Primary School Children (일부 초등학생의 기본심폐소생술 교육효과에 대한 연구)

  • Kang, Hea-Eun;Kim, Hyeon-Suk;Kim, Yun-Shin
    • Journal of the Korean Society of School Health
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    • v.24 no.1
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    • pp.118-128
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    • 2011
  • Purpose: This research is based on experiments practiced with 6th grade students in primary school as subjects. They were trained in basic cardiopulmonary resuscitation theory and received actual training in CPR. Methods: The subjects were randomly sorted into two classes of the 6th grade students. The experimental group was composed of 35 students. The control group was composed of 32. The experimental group received basic CPR theoretical and practical education once and received a practical evaluation three times, with 4 weeks in between evaluations. The control group received CPR theoretical education before the study. The data was analyzed by ${\chi}^2$-test and t-test using the SPSS/WIN 12.0 program. Results: Hypothesis 1 was that the basic CPR knowledge score would begin to decrease right after the education and continue to decrease as time passed. The experimental group's knowledge score continued to increase 12 weeks after education, but there was no decrease in the control group's knowledge score (F=5.870, p=.000). Hypothesis 2 was that the basic CPR attitude score would decrease right after the education and continue as time passed. There was no significant difference in the experimental group's score after education, nor was there any change in the control group's score on this measure (F=3.986, p=.004). Hypothesis 3 was that the subjects' confidence in practicing CPR would decrease right after education and continue as time passed. There was a significant decrease in the experimental group's score, but no significant change in the control group's score on this measure (F=75.574, p=.000). Hypothesis 4 was that the practical accomplishment evaluation score of CPR would decrease as time passed. There was a significant decrease in the experimental group's score on this measure right after education (F=38.368, p=000). Conclusion: Retraining for basic CPR education will be needed in all aspects of the education/training at least every 4 weeks, to preserve the students' retention of learned material/training. This is because students' scores fell significantly four weeks after education/training.

Validation of an Instrument to Measure Exercise of Self-Care Agency and its Predictors (자가간호역량의 행사 측정도구의 타당성 및 예측요인 조사)

  • 소향숙;이은숙
    • Journal of Korean Academy of Nursing
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    • v.19 no.3
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    • pp.273-284
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    • 1989
  • The aim of this investigation was to delineate concepts contributing to the Exercise of Self-Care Agency (E.S.C.A.) Scale developed by Kearney & Fleischer (1979) and to test its construct validity and its predictors. The results are summarized as follows ; 1. By means of principal factor analysis and maximal likelihood factor analysis upon data generated from 280 undergraduate students, the factors of Concern about Health Knowledge, self-Concept, Information - Seeking Behavior, Decision -making and Responsibility, Self-esteem, and Passivity emerged. The total percent of variance explained by the 6 factors was 75.1% 2. To assess factor independence and instrument homogeneity, correlations among the 6 factors were computed. The correlations ranged from .24 to .46 indicating that the factors and the items were not too similar or redundant. 3. Test-retest reliability of the total scale is r=.70. Cronbach's $\alpha$ coefficient for internal consistency of the total scale is .86 and that of the factors ranged from .750 to .661 (only factor 6 .497). 4. In additional analysis of the Exercise of Self-Care Agency Scale in relationship to Multiple Health Locus of Control, Family Environmental Scale, and Cornell Medical Index using stepwise multiple regression, the Internal Health Locus of Control Score predicted 21.8%(F=53.34, p=.0001), Family Environmental Score 8.3%(F=22.59, P=.0001), Modified Cornell Medical Index Score 5.4%(F=15.74, P=.0001) of the score of the E.S.C.A.

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Developing a Pedestrian Satisfaction Prediction Model Based on Machine Learning Algorithms (기계학습 알고리즘을 이용한 보행만족도 예측모형 개발)

  • Lee, Jae Seung;Lee, Hyunhee
    • Journal of Korea Planning Association
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    • v.54 no.3
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    • pp.106-118
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    • 2019
  • In order to develop pedestrian navigation service that provides optimal pedestrian routes based on pedestrian satisfaction levels, it is required to develop a prediction model that can estimate a pedestrian's satisfaction level given a certain condition. Thus, the aim of the present study is to develop a pedestrian satisfaction prediction model based on three machine learning algorithms: Logistic Regression, Random Forest, and Artificial Neural Network models. The 2009, 2012, 2013, 2014, and 2015 Pedestrian Satisfaction Survey Data in Seoul, Korea are used to train and test the machine learning models. As a result, the Random Forest model shows the best prediction performance among the three (Accuracy: 0.798, Recall: 0.906, Precision: 0.842, F1 Score: 0.873, AUC: 0.795). The performance of Artificial Neural Network is the second (Accuracy: 0.773, Recall: 0.917, Precision: 0.811, F1 Score: 0.868, AUC: 0.738) and Logistic Regression model's performance follows the second (Accuracy: 0.764, Recall: 1.000, Precision: 0.764, F1 Score: 0.868, AUC: 0.575). The precision score of the Random Forest model implies that approximately 84.2% of pedestrians may be satisfied if they walk the areas, suggested by the Random Forest model.

A study on the Family Caregiver Burden for Psychiatric Out-Patients (정신과 외래환자의 자가간호수행 및 가족기능과 가족 부담감의 관계)

  • Kim, Yeon-Hee
    • Research in Community and Public Health Nursing
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    • v.5 no.1
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    • pp.64-80
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    • 1994
  • The purpose of this study was to identify factors affecting family caregiver burden, and to identify the relationship between family caregiver burden and family function /self-care of psychiatric out-patient. These data were collected by questionnaire from September 20 to October 8, 1993. The subjects were 285 family caregiver of psychiatric out-patients. The instruments used in this study were Caregiver Burden Inventory(CBI) by Novak(1989), self-care performing by Yu(1992), and Family APGAR by Smilkstein(1979). The data were analyzed by cronbach's $\alpha$, mean, standard deviation, percentage, t-test, ANOVA, Pearson's correlation coefficient, and Stepwise Multiple Regression with SPSS /pc+ program. The result of this study were as follows ; 1. The means of family caregiver Burden revealed total 2.00, Time-Dependence Burden 78, developmental Burden 2.22, physical Burden 1.90, social Burden 1.43, emotional Burden 2.18, financial Burden 1.51. family caregiver burden score showed moderate level. time-dependence burden showed the highest score and social burden showed the lowest score. 2. The means of family function revealed total 5.67. 7 through high-21.4% (61), low through 3-38.6%(110). family function score showed moderate level. 3. The means of patient's self-care performance revealed total 137.71. self-care performance showed moderate level. 4. A ststistically significant correlation between family caregiver burden and patient's demographic variables, age (F=3.83, p<.01), marrital status(F=3.50, p<.01), job(F=3.17, p<.01), diagnosis(F=4.46, p<.01), income (F=4.46, p<.01). No significant differences between family caregiver burden and prevalent period, religion, sex (p>.05). S. A ststistically significant correlation between family caregiver burden and family's demographic variables, age (F=7.34, p<.01), sex(t=-2.63, p<.01), education level(F=7.61, p<.01), income (F=8.13, p<.01), relation with patient (F=6.92, p<.01), job(F=2.03, p<.05), medical service (F=3.89, p<.05), presence of chronically ill without patient(t=-2.01, p<.05) 6. Family function was the highest factor predicting family caregiver burden(R=.4168, $R^2=.1737$), low education level of family, patient's self-care, family income accounted for 36% in family caregiver burden.

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The Effects of Craniosacral Therapy on Chronic Headache (만성 두통환자에 대한 두개천골요법의 효과)

  • Choi, Song-Sil;Park, Hyoung-Sook
    • The Korean Journal of Rehabilitation Nursing
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    • v.7 no.1
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    • pp.68-77
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    • 2004
  • The Purpose of this study is to explore the effects of Craniosacral therapy(CST) on the chronic headache patients, and the research was used the one-group pretest-posttest design. The subjects were 31 chronic headache patients, who received Craniosacral therapy by once per week for 6 weeks. The data were collected from July 1, 2003 to August 28, 2003. In order to evaluate the effects of craniosacral therapy, Visual Analogue Scale(VAS) for headach intensity, blood pressure, pulse rate, respiration rate, craniosacral rhythm rate, depression and stress perception were measured before and after treatment. The results are as follows : 1) The mean score of intensity of headache (VAS) significantly decreased after each session of Craniosacral therapy(F=86.14, p<.001). 2) The mean score of systolic blood pressure significantly decreased after each session of craniosacral therapy(F=6.99, p<.001), and the mean score of diastolic blood pressure significantly decreased after 3rd session of Craniosacral therapy(t=5.710, p<.001). The means of pulse(F=6.19, p<.001), respiration (F=7.93, p<.001) and craniosacral impulse rate(F=22.84, p<.001) significantly decreased after each session of Craniosacral therapy. 3) The means score of depression significantly decreased after Craniosacral therapy(t=6.627, p<.001) and stress also significantly decreased after Craniosacral therapy(t=5.987, p<.001). Therefore, these results of this study suggest that Craniosacral therapy could be an effective nursing intervention to reduce the intensity of headache.

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