• The Journal of the Korea Contents Association
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• v.17 no.3
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• pp.212-221
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• 2017

This study was identify the effective factors on the subjective quality of life of the elderly. The data were collected on September 4, the subjects were 201 elderly who participated in the 1004day event in B metropolitan city. The data were analyzed by SPSS 20.0 program using descriptive statistics, t-test, ANOVA, Scheffe's test. Pearson's correlation coefficient and Stepwise Multiple Regression. The level of subjective quality of life was affected by general characteristics including education level(F=5.87, p=.001), living with whom(F=4.39, p=.005), perceived economic state(F=16.25, p<.001). The subjective quality of life of the elderly showed a positive correlation with subjective health status, social activity and family support. According to the result of multiple regression analysis, Factors affecting the subjective quality of life is subjective economic status, living with whom, family support and, social activities, it was explained by 23.6%. Based on these findings in order to improve the subjective quality of life of the elderly by developing improved family support programs and various social activities program proposes to apply.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2003.10a
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• pp.3-3
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• 2003

With biomedical literature expanding so rapidly, there is an urgent need to discover and organize knowledge extracted from texts. Although factual databases contain crucial information the overwhelming amount of new knowledge remains in textual form (e.g. MEDLINE). In addition, new terms are constantly coined as the relationships linking new genes, drugs, proteins etc. As the size of biomedical literature is expanding, more systems are applying a variety of methods to automate the process of knowledge acquisition and management. In my talk, I focus on the project, GENIA, of our group at the University of Tokyo, the objective of which is to construct an information extraction system of protein - protein interaction from abstracts of MEDLINE. The talk includes (1) Techniques we use fDr named entity recognition (1-a) SOHMM (Self-organized HMM) (1-b) Maximum Entropy Model (1-c) Lexicon-based Recognizer (2) Treatment of term variants and acronym finders (3) Event extraction using a full parser (4) Linguistic resources for text mining (GENIA corpus) (4-a) Semantic Tags (4-b) Structural Annotations (4-c) Co-reference tags (4-d) GENIA ontology I will also talk about possible extension of our work that links the findings of molecular biology with clinical findings, and claim that textual based or conceptual based biology would be a viable alternative to system biology that tends to emphasize the role of simulation models in bioinformatics.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.29 no.2B
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• pp.155-162
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• 2009

Univariate frequency analyses are widely used in practical hydrologic design. However, a storm event is usually characterized by amount, intensity, and duration of the storm. To fully understand these characteristics and to use them appropriately in hydrologic design, a multivariate statistical approach is necessary. This study applied a Gumbel mixed model to a bivariate storm frequency analysis using hourly rainfall data collected for 46 years at the Seoul rainfall gauge station in Korea. This study estimated bivariate return periods of a storm such as joint return periods and conditional return periods based on the estimation of joint cumulative distribution functions of storm characteristics. These information on statistical behaviors of a storm can be of great usefulness in the analysis and assessment of the risk associated with hydrologic design problems.

• Journal of Korean Tunnelling and Underground Space Association
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• v.24 no.6
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• pp.539-552
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• 2022

In the case of train stations, due to the specificity of underground spaces with limited smoke emissions, if appropriate removal equipment is not equipped, the damage caused by fire smoke may increase in the event of a fire. As a result, the need for measures to ensure the safety of evacuation of underground stations has been highlighted, and research for safe evacuation of platform users in case of fire is continuously being conducted at home and abroad. However, although the smoke removal area is currently divided by smoke boundary walls and platform screen doors (PSD) and installed in the train platform, standards for smoke removal methods (air supply or exhaust) for each fire removal area, that is, smoke removal mode, are not presented. In this study, fire analysis and evacuation analysis were performed to estimate the number of deaths and to derive F/N guidance in order to quantitatively evaluate the fire risk according to the fire station fire, and the total risk was the lowest in the case of fire area exhaust and supply to adjacent areas.

• Journal of Korean Society on Water Environment
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• v.33 no.1
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• pp.1-7
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• 2017

Bioretention systems, an advance low impact development and green infrastructure approach were currently utilized in different parts of the world because it promotes biodiversity thereby mimicking and preserving the pre-developed state of an area. This study investigated and compared the capability of four bioretention systems to identify factors affecting the hydraulic capabilities and pollutant removal efficiencies of each system. The two bioretention type A referred as Type A-C and Type A-FC were planted with perennials such as Chrysanthemum and Fan columbine, respectively. On the other hand, the two type B bioretention systems referred as Type B-A and Type B-JM were planted with shrub plant species such as Azalea and Japanese Meadowsweet, respectively. Based on the results, TV, infiltration mechanism, filter media depth and plant species were identified as the factors affecting the difference in flow attenuation, retained volume and pollutant removal efficiency of Type A-C, Type A-FC, Type B-A and Type B-JM bioretention systems. The design of bioretention Type B-A and Type B-JM were advantageous considering greater volume retention, groundwater recharge, longer HRT and peak flow attenuation and greater pollutant removal efficiency. On the other hand, the design of bioretention Type A-C and Type A-FC was more appropriate for design considering reduced groundwater contamination.

• Journal of Photoscience
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• v.7 no.3
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• pp.87-95
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• 2000

As sunlight not always optimized for every terrestrial plant in terms of light quality, quantity and duration, some plants suffer detrimental effects of sunlight exposure under certain conditions. Photoinhibition of photosynthesis is a typical phenomenon representing harmful light effects, commonly observed in many photosynthetic organisms. It is generally accepted that functional, structural loss of photosystem II complex(PSII) is the primary event of photoinhibition. Accumulating data also suggest that singlet oxygen($^1$O$_2$) is the main toxic species directly involved in it. There are two different views on the specific site and mechanism of $^1$O$_2$ production in the photosynthetic membrane. One of them favors the PSII reaction center, where the primary charge pairs recombination occurs as a prerequisite for the generation of $^1$O$_2$, and the other inclines to photosensitized $^1$O$_2$ formation by a substance located outside PSII. This article describes how we, as the advocators of the latter concept, have arrived at the conclusion that $^1$O$_2$ immediately involved in PSII photodamage is largely generated from the Rieske center of the cytochrome b$_{6}$/f complex and diffuses into PSII, attacking the reaction center subunits.s.

• Nuclear Engineering and Technology
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• v.44 no.8
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• pp.855-870
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• 2012

The paper deals with three main topics: a) the definition of System Thermal-Hydraulics (SYS TH), b) a historical outline for SYS TH and, c) the description of elements for reflection when planning research projects or improvement activities, this last topic being the main reason for the paper. Distinctions between basic thermal-hydraulics and computational Fluid-Dynamics (CFD) on the one side and SYS TH on the other side are considered under the first topic; stakeholders in the technology are identified. The proposal of Interim Acceptance Criteria for Emergency Core Cooling Systems in 1971 by US NRC (AEC at the time) is recognized as the starting date or the triggering event for SYS TH (second topic). The complex codes and the main experimental programs (list provided in the paper) constitute the pillars for SYS TH. Caution or warning statements are introduced in advance when discussing the third topic: a single person (or a researcher) has little to no possibility, or capability, of streamlining the forthcoming investments or to propose a roadmap for future activities. Nevertheless, the ambitious attempt to foresee developments in this area has been pursued without constraints connected with the availability of funds and with industrial benefits or interests. Demonstrating the acceptability of current SYS TH limitations and training in the application of those codes are mentioned as the main challenges for forthcoming research activities.

• Nuclear Engineering and Technology
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• v.48 no.1
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• pp.114-128
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• 2016

The development of operational performance indicators is of utmost importance for nuclear power plants, since they measure, track, and trend plant operation. Leading indicators are ideal for reducing the likelihood of consequential events. This paper describes the operational data analysis of the information contained in the Corrective Action Program. The methodology considers human error and organizational factors because of their large contribution to consequential events. The results include a tool developed from the data to be used for the identification, prediction, and reduction of the likelihood of significant consequential events. This tool is based on the resilience curve that was built from the plant's operational data. The stress is described by the number of unresolved condition reports. The strain is represented by the number of preventive maintenance tasks and other periodic work activities (i.e., baseline activities), as well as, closing open corrective actions assigned to different departments to resolve the condition reports (i.e., corrective action workload). Beyond the identified resilience threshold, the stress exceeds the station's ability to operate successfully and there is an increased likelihood that a consequential event will occur. A performance indicator is proposed to reduce the likelihood of consequential events at nuclear power plants.

• International Journal of Advanced Culture Technology
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• v.9 no.2
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• pp.72-79
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• 2021

This study is to develop a strategy to prepare an improvement strategy according to the environmental change of the hotel. Currently, domestic hotels are implementing marketing through food and beverage as a countermeasure against the sales decrease, and in order to develop effective marketing plan, 5 Force Model environmental analysis and STP analysis are analyzed. 5 Force Model Environmental Analysis showed that domestic hotels are facing various difficulties such as the expansion of accommodation sharing system, the decrease of Chinese tourists due to the THAAD problem, the increase of hotels, the introduction of PMS, the increase of minimum wage, the introduction of 52 hours work week, and the increase in product preference As an STP response strategy to correspond these difficulties, it is necessary to develop products for the main customers of the hotel food and beverage, such as those in the 20s-30s, the workers, smartphones and SNS users. And also hotels should seek ways to lower price of the product to the level desired by the user to compete against substitutes. In conclusion we suggest that hotels are committed to fulfilling their role by meeting guest safety and COVID-19 compliance requirements, but a focus on immediate cleanliness and quarantine against infectious diseases, like Airbnb, will enable greater growth.

• Molecular Medicine Reports
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• v.20 no.4
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• pp.3301-3307
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• 2019

c-Myc is a characteristic oncogene with dual functions in cell proliferation and apoptosis. Since the overexpression of the c-Myc proto-oncogene is a common event in the development and growth of various human types of cancer, the present study investigated whether oncogenic c-Myc can alter natural killer (NK) cell-mediated immunity through the expression of associated genes, using PCR, western blotting and flow cytometry assays. Furthermore, whether c-Myc could influence the expression levels of natural killer group 2 member D (NKG2D) ligands, which are well known NK activation molecules, as well as NK cell-mediated immunity, was investigated. c-Myc was inhibited by 10058-F4 treatment and small interfering RNA transfection. Upregulation of c-Myc was achieved by transfection with a pCMV6-myc vector. The inhibition of c-Myc increased MHC class I polyeptide-related sequence B and UL16 binding protein 1 expressions among NKG2D ligands, and the overexpression of c-Myc suppressed the expression of all NKG2D ligands, except MHC class I polyeptide-related sequence A. Furthermore, the alteration of c-Myc activity altered the susceptibility of K562 cells to NK cells. These results suggested that the overexpression of c-Myc may contribute to the immune escape of cancer cells and cell proliferation. Combined treatment with NK-based cancer immunotherapy and inhibition of c-Myc may achieve improved therapeutic results.