Hydrogel coated ring shaped ocular inserts (containing the antibiotic, tylosin tartrate) were used in an evaluation of the effectiveness of polymeric ocular drug release devices for treating infectious bovine keratoconjunctivitis. The in vivo experiments represent the first experiments using hydrogel ocular inserts containing an antibiotic for treating infectious bovine keratoconjunctivitis. In the infection tests, ten calves. were challenged with $2.4{\times}10^8{\sim}1.6{\times}10^9$ Moraxella bovis (a bacterium) colonies per eye following two ten minute ultraviolet radiation eye preconditioning exposures. Ninety five percent of the eyes (19 of 20 eyes) were successfully infected by this method. All infected eyes were monitored for the presence of the bacteria quantitiatively, and clinical observations were made for 14 days. The test was performed by three consecutive steps: 1) inoculation with 2 ultraviolet (UV) radiations, 2) growth of bacterial colonies and 3) treatment with medicated ring-shaped devices. The first. bacteriological measurements after 2 UV exposures were performed at day 3 of the tests. At day 7 after inoculation of both eyes of a calf with M. bovis, a medicated or a non-medicated ring-shaped device was inserted into each eye of a calf. The eye receiving the non-medicated ring was taken as a control for comparison with the eye that received a medicated ring. During the next 7 day period following a medicated ring insertion, the number of bacteria in the treated eyes dropped dramatically to negligible levels (0 to 30 colony forming units/swab), while the control eyes which received a non-medicated ring still exhibited a relatively high number of bacteria ($10^3\;to\;10^6$ colony forming units/swab). The number of bacteria was significantly reduced by the antibiotic released from the medicated ocular insert.
PET fabrics of various luster, fiber thickness(denier), and weaving structure were dyed at the same conditions and determined their grey scale by using naked eyes, computer color matching (CCM) system, and real industry color (RIC) device to evaluate the effectiveness of RIC device developed in this study. As for the luster of fabrics, bright PET showed more differences when compared with semi-dull and full-dull. PET in both naked eyes and RIC device since the RIC device provide the real image of fabrics to observers. As for the fiber thickness, the results of naked eyes and RIC device were very similar while the result of CCM showed lower color grade. Finally, as for the weaving structures of PET fabrics, all the test results by naked eyes, CCM, and RIC device showed almost same grey scales. In these regards, the RIC device developed in this study was comparable to naked eyes by providing the real image of fabrics, however it was difficult to compare the very bright colors such as yellow and fiber thickness(denier) and weaving structure of fabrics.
The Journal of the Society of Korean Medicine Diagnostics
/
v.12
no.2
/
pp.49-60
/
2008
Objectives: The aim of this study was to investigate correlation of the phlegm-retained fluid, namely Damum(痰飮) and dark circles under eyes. Methods: 2 males and 11 females aged 26-60 years were participated in this study. They were asked the intensity of 29 symptoms related with Damum(痰飮) including dark circle with the questionnaire published by the Journal of the Korea Institute of Oriental Medical Diagnostics. Three skin researchers including OMD graded the dark circles by inspection. We took the pictures around eyes by Facial Stage (Moritex, Japan) and analyzed the skin color by Image-Pro Plus (Media Cybernetics, USA). Results: There was statistically significant correlation between Damum(痰飮) and dark circles measured by self, inspectors and image analysis. Conclusions: In the Oriental Medicine, It is reported that the shadows under eyes are the sign of the retention of fluid, Damum(痰飮). In our study, that shadows, namely dark circles, has correlation with the symptoms of Damum(痰飮). Especially, the correlation between inspected grade and image analysis was very high. According to the above results, it is proved that dark circles under eyes are important diagnostic sign of Damum(痰飮).
The eyes of Nilaparvata lugens were examined for ultrastructural changes in the light and dark adapted states. Inspection of light microscope sections taken at similar levels of compound eyes from insects kept in light or darkness for periods up to 72 hors revealed some differences between light and dark adapted eyes. Using the electronmicroscope, in light adapted eyes the palisade layer was narrower than that in dark adapted eyes. The pigment granules still formed a ring around the palisade layer in the dark adapted eye but, they did not form a tight circle around the rhabdom. No constant difference was found between the diameters of the microvilli in light and dark adapted eyes. The pigment movements at the junction of the cone and the rhabdom took the effect on varying the pigment aperture at the tip of the cone in front of the rhabdom tip.
This study aimed to conduct an eye-tracking experiment carried with facade images as a medium and to do research on 'the interest of the eyes' resulted from people's gazing phenomena. This study secured gazing data which appeared according to visual response and analyzed gazing phenomena to find the basic theory of 'the interest of the eyes' as a methodological role, which consumer interest and attention could be grafted when a plan and a design for space design was made. Data terms used in eye-tracking backgrounds and the movement of the eyes were investigated in literature review. Twenty (20) facade images were selected through a case study to get experimental stimuli for the related experiment. Thirty (30) subjects (men and women) suitable for the experiment were recruited to conduct an eye-tracking experiment. After the experiment, five (5) areas were set up in the facade image to identify the focus level of interest and attention. The level of interest and focus was connected to the interest of the eyes. The analysis to study the interest of the eyes was based on nine (9) items such as sequence, entry time, dwell time, hit ratio, revisits, revisitors, average fixation, first fixation and fixation count. Through gaze analysis, the following conclusion was drawn about the 'interest level of sight' for gaze frequency. The interest level can be interpreted to be higher for faster sequence, shorter entry time, longer all fixation(ms) for dwell time, faster all saccade(%), higher hit ratio, more revisits, more revisitors, longer average fixation, faster and longer first fixation, and more fixation count, and the person can be said to have felt interest faster and/or more.
The purpose of this study was to investigate the effect of aqua exercise program on the static balance of child with mental retardation. The subjects were seven male child and three female child with mental retardation(age ranges from 5 to 6). The subjects were practiced with focusing on the aqua exercise program for 8 weeks, from 7, January 2003 to 28, February 2003. The results of this study were as follows : 1. After the exercise program, the balance of double-stance by BPM was significantly reduced of lateral sway number by $12.2\%$(P<.01) with eyes obstruct. 2. After the exercise program, the balance of double-stance by BPM was significantly reduced of anterior and posterior sway number of left leg by $8.5\%$(P<.05) with eyes obstruct. 3. After the exercise program, the balance of double-stance by BPM was significantly reduced of anterior and posterior sway number of right leg by $8.3\%$(P<.05) with eyes obstruct. 4. After the exercise program, the balance of double-stance by BPM was significantly reduced of lateral sway number by $13.2\%$(P<.01) with eyes open. 5. After the exercise program, the balance of double-stance by BPM was significantly reduced of anterior and posterior sway number of left leg by $10.3\%$(P<.05) with eyes open. 6. After the exercise program, the balance of double-stance by BPM was significantly reduced of anterior and posterior sway number of right leg by $10.3\%$(P<.01) with eyes open. As we can see the results of this study, the aqua exercise program improved the static balance of child with mental retardation. Futhermore, it is reasonable program that can improvability of static balance for the children with mental retardation using aqua exercise program. And then it is necessary to develop much better program than now for the children with mental retardation's health and to provide the adequate pool for their aqua exercise.
This study was aimed to evaluate the prophylactic anti-glaucoma effect of topical 5% betaxolol (BTX) and 2% dorzolamide (DRZ) on the second eye in dogs with unilateral primary angle closure glaucoma (PACG). Medical records of 60 dogs with unilateral PACG who received prophylactic anti-glaucoma eyedrops in the second eye, from 2016 to 2021, were reviewed. The prophylactic effects of BTX were maintained on 28/60 (46.7%) eyes until last visit and BTX failure was observed on median 510 (range, 53-1,927) days in 32/60 (53.3%) eyes. After DRZ instillation in BTX failure eyes, the prophylactic effects were extended at median 610 (range, 157-2,270) days in 21/32 (65.6%) eyes. DRZ failure eyes (17/21, 81.0%) eyes required chemical ablation or surgical intervention due to uncontrolled intraocular pressure. The duration of prophylactic effects was decreased with aging (R2 = 0.334, p = 0.006). The predominant breeds were Shih-Tzu (41.9%) and American Cocker Spaniel (30.6%) with no significant differences in survival curves (p = 0.210). The average prophylactic effects of BTX persisted more than 1.5 year and could be selected the first prophylactic eye drop in unilateral PACG. Also, early surgical intervention should be considered in prophylactic medications failure cases.
The use of intraoperative application of Mitomycin C at the filtration site has been known to improve the surgical outcome in glaucomatous eyes with high risk for failure of trabeculectomy. The author performed trabeculectomies with intraoperative Mitomycin C on 25 eyes of 20 patients with poor surgical prognosis to study the efficacy and safety of this technique in glaucomatous patients with high risk for failure of trabeculectomy. After the preparation of a scleral flap, 0.2mg/ml solution of Mitomycin C was applied between Tenon's capsule and the sclera for 2 minutes. The exposed area was then irrigated with 200 ml of balanced salt solution. The follow-up period was from 1 to 7 months (mean 3.8 months). The mean preoperative intraocular pressure (IOP) was $38.6{\pm}6.6mmHg$. The mean final postoperative IOP was $11.7{\pm}3.8mmHg$. Twenty three (88%) of the 25 eyes were successfully controlled with the IOP of less than or equal to 20 mmHg without glaucoma medication. There were early postoperative complications of hyphema in 5 eyes (20%), shallow anterior chamber in 4 eyes(16%), punctate keratopathy in 3 eyes (12%), aqueous leaking from conjunctival wound in 2 eyes (8%), encapsulated bleb in 1 eye (4%) and choroidal detachment in 1 eye (4%), and 4 eyes had long term hypotony lasting more than 2 months. Although Mitomycin C is simple to use and effective adjunct to trabeculectomy, further study will be needed to determine the mechanism of action, indication, dosage and optimal exposure time of Mitomycin C.
The starting point of this discussion resides in the 'eyes' of mirror in a sense of seeing the self reflected in a mirror. The meaning of mirror has been evolved over the centuries while strengthening its sense of identity by bringing up some questions for resemblance, reproduction, self-reflection and reality. A mirror has also extended its vision and provided with a range of images that the self can't have. In this regard, looking into a mirror has been a sustained focus of attention by creating another ostensible being of self-image. This shows the two sides of mirror, which reveals an ambiguous gap between substance and illusion. An excessive immersion in a reflected image in a mirror is intensified and expressed today. The eyes of mirror consisting of a complex dual structure show relations between a person who sees and a person who is seen, which draws a hazy line of demarcation between the subject and the object. This opens up the possibility of the world of chiasme, where you could face all the aspects being from the eyes of others. Furthermore, the meaning of the reflection in a mirror has formed a creative discourse as an enigmatic medium that creates a variety of 'eyes' in various forms of aesthetic expression like paintings and literature. I accordingly suggest that the 'eyes of mirror' is the ambiguous 'eyes of human being' reflected in two territories of the world. Therefore, I will present the historical development of the perspective on the mirror to take a concrete approach in which it opens up the reflective structure of resemblance through a series of examples projected onto the literary and artistic productions. This study will serve as ruminations on the fact that your life is being existent in 'chiasme' of mutual entanglement between the self and the world by investigating relations between a person who sees and a person who is seen, in other words, relations between the perceiving subject and the eyes of others reflected in a mirror.
Journal of the Korea Society of Computer and Information
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v.27
no.12
/
pp.259-266
/
2022
In this paper, we propose a study is to prepare basic data for integrated health promotion education by preventing dry mouth and dry eyes through lifestyle management. From October 7 to 17, 2022, a total of 516 respondents who voluntarily agreed and responded through a self-written structured questionnaire were statistically analyzed for university students in their 20s across the country. As for the factor of feeling dry mouth among the living habits of the study subjects, the more smoking per day, the higher(8.41±2.041) and very high(7.75±2.927) felt dry mouth(p=.015), and the time spent using smart phones. The shorter this was, the lower(1.16±0.784) and very low(1.83±1.672) felt dry mouth(p=.022). The main factors contributing to dry mouth and dry eyes were dry eyes (odds ratio 3.651, p=.000), and high smoking(odds ratio 0.916, p=.038), and the more you use your smart phone (odds ratio 0.256, p=.004), the more you feel dry mouth. When feeling dry eyes, they felt dry mouth more(odds ratio 4.002, p=.000), and the more they exercised, the more dry eyes they felt(odds ratio 1.600, p=.009). As a result, since dry mouth and dry eyes appear as common inconveniences, it was found that lifestyle management is necessary to maintain and promote a healthy life. Therefore, it is proposed to build an integrated health platform that can improve the quality of life and implement personalized health management programs.
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