• Title/Summary/Keyword: Extreme condition

검색결과 413건 처리시간 0.032초

Functions of Monocyte Chemotactic Protein-3 in Transgenic Mice Fed a High-Fat, High-Cholesterol Diet

  • An, So Jung;Jung, Un Ju;Choi, Myung-Sook;Chae, Chan Kyu;Oh, Goo Taek;Park, Yong Bok
    • Journal of Microbiology and Biotechnology
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    • 제23권3호
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    • pp.405-413
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    • 2013
  • Monocyte chemotactic protein-3 (MCP-3), a chemokine that is in a superfamily of structurally related small chemotactic cytokines involved in leukocyte trafficking, is regarded as a key factor in atherogenesis. In this study, we examined the changes in atherogenic parameters including hepatic lipid accumulation and oxidative balance in MCP- 3-overexpressing transgenic mice (MCP-3 mice) under atherogenic conditions. To induce an extreme atherogenic condition, mice were fed a high-fat, high-cholesterol (HFHC) diet for 12 weeks. The body weight and food intake were not changed by MCP-3 overexpression in the aorta. On a HFHC diet, the MCP-3 mice had higher plasma levels of total cholesterol and a higher atherogenic index compared with wild-type mice, although there were no differences in the plasma HDL-cholesterol and triglyceride levels. Furthermore, an increase in lipid accumulation was observed in the aortas as well as the livers of the HFHC diet-fed MCP-3 mice compared with wild-type mice. The activities of antioxidant enzymes increased in the livers of the HFHC diet-fed MCP-3 mice, whereas supplementation with antioxidants, naringin and hesperidin, reversed the activities of the hepatic antioxidant enzymes in HFHC diet-fed MCP-3 mice, indicating that there might be more oxidative damage to the tissues in the HFHC diet-fed MCP-3 mice leading to progression towards atherosclerosis and hepatic steatosis. Microarray analyses of the aorta revealed atherosclerosis-, PPARs-, lipoprotein receptor, and apolipoprotein-related genes that were affected by the HFHC diet in MCP-3 mice. These findings suggest that aortic MCP-3 overexpression may contribute to the development of atherosclerosis and hepatic steatosis under atherogenic conditions.

습식 세정법에서 암모니아 대체물질에 관한 연구 (Studies on the aqueous ammonia alternatives in the wet scrubbing method)

  • 김재강;이주열;박병현;최진식
    • 한국응용과학기술학회지
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    • 제33권1호
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    • pp.110-117
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    • 2016
  • 기존 연구에서는 스크러버를 이용한 $NO_2$ 를 제거하기 위해 암모니아 수용액을 적용한다. 하지만 암모니아는 독성 및 악취가 강해 실선 적용에 어려움이 따를 수 있어, 암모니아를 대체할 수 있는 물질을 찾기 위해 이 연구를 진행하였다. 대체 물질로는 수산화나트륨(NaOH), 티오황산나트륨($Na_2S_2O_3$), 요소(Urea)를 사용하였다. 세정액을 제외한 모든 부분은 기존 암모니아를 적용한 실험의 최적 조건과 동일하게 진행하였다. 그 결과 실험에 사용된 세 가지 물질 중 두 물질은 암모니아 용액과 대체가 가능한 것으로 사료되었으며, 최적조건은 각각 NaOH 2.5 %, $Na_2S_2O_3$ 5.0 % 에서 가장 높은 효율을 나타냈다. Urea는 효율이 일정하게 지속되지 않아 대체 물질로는 적합하지 않음을 확인 할 수 있었다.

1930년대 김종량의 H자형 한일절충식 도시주택 (Kim, Jong-Ryang's H-shaped Houses in 1930s in Seoul)

  • 백선영;전봉희
    • 건축역사연구
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    • 제18권5호
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    • pp.7-24
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    • 2009
  • This stydy investigates H-shaped houses in 1930s and examines the characters and meanigs of Kim, Jong-Ryang's H-shaped houses as a new trial to urban Hanok of those days. He, who was concerned about the housing problem of Seoul, made an attempt to make various types of dwellings. Among them, this study focuses on Japanese-Korean Style H-shaped houses in Samcheong-dong. As the alternative housing type against other urban Hanok of Seoul in 1930s, the H-shaped houses of Kim, Jong Ryang had characters as follows : 1) H-shaped houses has two special characters. First, the whole space of a single house can be divided into a left region and a right region. Second, it can be divided to a front region and a rear region. In his H-shaped houses, the left/right division was expressed as folding of space-layers in parallel with urban streets. The front/rear division was used as classification of main-living space and sub-living space. 2) KJR's H-shaped Japanese-Korean Style houses were proved to be designed as urban housing against the extreme housing shortage of Seoul in 1930s. 3) His houses however were not accepted broadly as a urban house type because the construction cost of those was higher than an average and the element of Japanese style house was not adapted to Korea. Kim, Jong-Ryang's trial is valuable because it was the rare case of realization of many discourses as defects of existing house type. With more rigorous investigations on KJR's experiment in modern house type, we could understand the housing condition of Seoul in 1930s and modern urban houses more than before.

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찰스 다윈의 '비글호 항해기'와 지구과학 (Charles Darwin's 'The Voyage of the Beagle)

  • 장순군
    • 한국지구과학회지
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    • 제21권4호
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    • pp.488-501
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    • 2000
  • 인류사상 가장 위대한 박물학자인 찰스 다윈(1809-82)이 쓴 사상 최고의 과학여행기인 '비글호 항해기'를 지구과학관점에서 검토했다. 항해기에는 지구과학에 관한 여러 가지의 관찰과 해석이 실려있다. 먼저 다윈이 지질시대가 당시 받아들여지던 것보다 훨씬 더 길다는 사실과 조산운동, 융기, 침강, 침식, 퇴적같은 지질현상과 지질과정을 이해했다. 그가 산호초가만들어지는 과정을 완전하게 설명했으며 생물의 진화에 관한 훌륭한 이론을 제안했다. 화석에 바탕을 두고 고환경을 이치에 맞게 복원한 내용이 항해기에 실려있다. 그가 관찰한 기상학에 관련된 내용으로는 대서양을 내려가면서 '비글'호에서 채집한 생물로 된 먼지부터 안데스산맥 능선에서 경험한 공기 움직임과 극도로 맑고 건조한 환경까지 여러 가지에 이른다. 일반 해양에 관한 관찰로는 바다의 변색을 비롯해 해면의 발광, 갈라파고스군도에서 발견된 패류구, 먼 섬에서 발견된 나무와 식물에 관한 것들과 다른 것들이 있다. 그러나 다윈이 육상여행을 상당히 많이 해서인지 천문학에 관한 기록이 거의 없다. 그의 해석과 제안의 대부분이 지금 받아들여진다.

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Verification on Cold-Tolerance of Some Fruit Trees as Species for Urban Greening Plants

  • Lee, Jin-Hee;Oh, Hee-Young;Kwon, O-Man
    • 한국환경과학회지
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    • 제26권10호
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    • pp.1155-1166
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    • 2017
  • This study selected commonly known species of fruit trees, and re-selected the species that endure the stress of extreme cold weather and physiologically restore themselves to the previous state until the following year. Then we could go ahead to propose the species that were appropriate as urban greening plants in weather condition of any part of the country. To do this, we conducted an experiments for six species of fruit trees based on the preference of the general public and recommendation of the experts; Morus alba (English name: mulberries), Diospyros kaki (English name: Persimmon), Prunus persia (English name: Peach), Elaeagnus umbellata var. coreana (English name: Korean Autumn Olive), Malus domestica 'Alps Otome' (English name: Alps Otome), and Prunus mume (English name: Blue Plum). The experiment verifies whether the trees survive without any stress from the cold weather under the national climate conditions (one in the suburbs of Seoul: Yongin city, one in the central Chungcheong region: Daejeon city, and in the southern Gyeongsang region: Jinju city in Korea). The experiment lasted for a year from August 2016 to August 2017. The levels of electrolytic efflux, chlorophyll content, plant height, fresh weight, and dry weight were measured four times (on August of 2016, January, February, and August of 2017) for each tree planted bare ground outdoors. Results showed that Diospyros kaki, Prunus persia, and Malus domestica 'Alps Otome' were proven durable and resistant to winters of all three areas (one in the suburbs of Seoul: Yongin city, one in the central Chungcheong region: Daejeon city, and in the southern Gyeongsang region: Jinju city in Korea). Especially, the increase of chlorophyll content and the reduction of electrolytic efflux were noticeable in Prunus persia than in the other two species, proving itself as the most cold-tolerant among the six species used in the experiment. In addition, interpreting from the physiological restoration data of one-year span before and after getting through winterer, Prunus persia was proven to be the most cold-tolerant species.

200 마력급 터보 블로워 적용을 위한 자기베어링 설계 (Design of Magnetic Bearings for 200 HP Class Turbo Blower)

  • 박철훈;윤태광;박준영
    • 한국유체기계학회 논문집
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    • 제18권6호
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    • pp.12-18
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    • 2015
  • Recently, the development trend of turbomachinery is high capacity and high efficiency. Most of turbomachinery in the market are adopting ball bearings or air foil bearings. However, ball bearings have a limit for high speed product over $2.0{\times}10^6DN$(product of the inner diameter of the bearing in mm (D) and the maximum speed in rpm (N)). Air foil bearings have a limit for high axial load for high power products over 200~300 HP(horse power). Magnetic bearing is one of the solutions to overcome the limits of high speed and high axial load. Because magnetic bearings have no friction between the rotor and the bearings, they can reduce the load of the motor and make it possible to increase the rotating speed up to $5.0{\times}10^6DN$. Moreover, they can have high axial load capacity, because the axial load capacity of magnetic bearing depends on the capacity of the designed electromagnet. In this study, the radial and thrust magnetic bearings are designed to be applied to the 200 HP class turbo blower, and their performance was evaluated by the experiment. Based on the tests up to 26,400 rpm and 21,000 rpm under the no-load and load condition, respectively, it was verified that the magnetic bearings are stably support the rotor of the turbo blower.

고분자전해질형 연료전지의 가습 방법에 대한 연구 (A Study of Humidification Method in PEMFC)

  • 한덕수;김준범
    • 전기화학회지
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    • 제6권3호
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    • pp.212-216
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    • 2003
  • 고분자전해질형 연료전지에 사용되는 외부 및 내부 가습기를 통과한 반응 기체의 상대습도와 온도를 측정한 자료가 실시간으로 컴퓨터에 입력되어지는 시스템을 자체적으로 구성하였다. 이 시스템을 이용하여 측정한 경우 10-20분이 경과한 후에 습도 값이 안정되었으므로 가습 측정치에 대한 신뢰성을 향상시킬 수 있었으며, 여러 가지 가습의 영향을 해석할 수 있었다. 측정 장비의 이상을 초래할 수 있는 상대 습도가 $100\%$부근의 영역에서 지속적으로 측정을 수행할 경우 센서의 오작동 내지 고장의 원인이 될 수 있었으므로 실험시 주의가 필요하였다. 가습기를 통과한 반응기체는 유량이 증가할수록 가습되는 양은 증가하나, 일정 유량 이상이 되면 그 증가폭이 감소하는 경향을 보였는데 이는 가습기 출 통과하는 기체의 체류 시간 영향에 기인한 것으로 추정되어진다.

화학기상증착법으로 성장시킨 단결정 6H-SiC 동종박막의 성장 특성 (Growth characteristics of single-crystalline 6H-SiC homoepitaxial layers grown by a thermal CVD)

  • 장성주;설운학
    • 한국결정성장학회지
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    • 제10권1호
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    • pp.5-12
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    • 2000
  • Silicon carbide(SiC)는 뛰어난 전기적, 열적, 물리적 특성 때문에 내환경 전자소자용 반도체 재료로 널리 연구되고 있다. 본 연구에서는 화학기상증착법으로 단결정 6H-SiC 동종박막을 성장시키고 이의 성장 특성을 조사하였다. 특히, 몰리브덴 (Mo)-plate를 이용하여 SiC를 코팅하지 않은 graphite susceptor를 사용한 6H-SiC 동종박막 성장조건을 성공적으로 얻었다. 대기압 상태의 RF-유도가열식 챔버에서 CVD성장을 수행하였고, <1120> 방향으로 $3.5^{\circ}$off-axis된 기판을 사용하였다. 성장 박막의 결정성을 평가하기 위하여 Nomarski 관찰, 투과율 측정 , 라만 분광, XRD, 광발광(PL) 분광, 투과전자현미경(TEM) 측 정 등의 방법을 이용하였다. 이상과 같은 실험을 통하여, 본 연구에서는 성장온도 $1500^{\circ}C$, C/Si flow ratio ($C_3H_8$ 0.2 sccm, $SiH_4$ 0.3 sccm)인 성장조건에서 결정성이 가장 좋은 6H-SiC 동종박막을 얻을 수 있었다.

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대구경 현장타설말뚝의 설계 사례 (Design of Large-scale Drilled Shaft)

  • 임철오;최영석;곽기석;장학성
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2009년도 세계 도시지반공학 심포지엄
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    • pp.545-553
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    • 2009
  • A lot of long-span marine bridge, which connects land to island or island to island, are being designed and constructed lately in south-west coast in South Korea. In the past, caisson foundations in marine were mainly adopted in construction and stability aspect, however, nowadays with development of pile construction technology, drilled shaft foundations are mainly adopted. As the long span cable stayed bridge and suspension bridge applied with lots of loads are being designed, the scale of pile foundations are getting larger. As the construction cost of substructure including foundation in marine bridges is too high, the appropriate evaluation of the axial bearing capacity of pile becomes a core factor to decide the construction cost of foundation if the drilled shaft is adopted as foundation type of bridge. The evaluation values of skin friction and end bearing capacity of drilled shaft in weathered rock suggested in south Korea are only to introduce the foreign specifications, and most of them are designed in a kind of hard soil layer. Also the allowable load of pile section is less than the expected bearing capacity of pile in the soil condition since the allowable capacity of pile is undervalued. Recently in order to improve this factor the bi-axial hydraulic load test of pile was taken, the data of load transfer analysis of pile, unit of skin friction and end bearing capacity are accumulated. In our country, the design of piles are made with ASD, however, LRFD considering service, strength and extreme state was adopted in Incheon Grand Bridge implemented with BTL, and the research to systematize the resistance coefficient appropriate at home country are being progressed.

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전족과 코르셋에 표현된 몸의 억압에 대한 의미해석 (A Study on Repression of the Female Body as Expressed by Chinese Foot-binding and the Western Corset)

  • 정기성;김민자
    • 복식
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    • 제61권7호
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    • pp.35-50
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    • 2011
  • In this study, repression of the body is defined as a restriction on natural developments or movements and a modification either temporarily or permanently of the human body in shape, color, texture and odor. In addition, it involves physical and (or) mental pain. Chinese foot-binding and the Western corset are extreme examples of female body's being repressed in the history of fashion. The analysis of this type of repression will be based on historical research and theoretical concepts such as Darwin's (1809-1882) survival condition, Freud's (1856-1939) renunciation of desire, Weil's (1909-1943) privilege, and Foucault's (1926-1984) L'Usage des Plaisirs(the use of pleasure). Chinese foot-binding symbolically represents ideal beauty, the distinction of an ethnic group, and a desire for improved social status in the struggle for political power. It also represents psychology and a esthetics of eroticism and fetishism that originate from a man's desire and his individual taste. Symbolically, the Western corset represents abundance and fecundity, obedience and devotion to religion, the sanctity of God and ideal beauty as defined by political power. It also represents psychology and aesthetics of eroticism and fetishism as man's desire and a fashion icon. In conclusion, Chinese foot-binding was pursuit of power in male ideology but Western corset was a power struggle between God and mankind.