• 제목/요약/키워드: Extramedullary

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Intradural Extramedullary and Subcutaneous Tumors in Neonate : Atypical Myxoid Spindle Cell Neoplasm

  • Yu, Dong-Woo;Choi, Joon-Hyuk;Lee, Eun-Sil;Kim, Seong-Ho
    • Journal of Korean Neurosurgical Society
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    • 제52권4호
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    • pp.417-419
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    • 2012
  • Tumors of the central nervous system are common in the pediatric population and constitute the second most prevalent tumor type in children. Within this group, spinal cord tumors are relatively rare and account for 1 to 10% of all pediatric central nervous system tumors. We describe a very rare case of an intradural extramedullary spinal cord tumor with a subcutaneous mass and discuss its clinical presentation, pathogenesis, and treatment. A male infant was delivered normally, with uneventful development. At 16 days post-delivery, his family took him to a pediatrician because of a mass on his upper back. Magnetic resonance imaging of the thoracic spine revealed a well-demarcated soft-tissue mass with central cystic change or necrosis at the subcutaneous layer of the posterior back (T2-7 level). Another mass was found with a fat component at the spinal canal of the T1-3 level, which was intradural extramedullary space. After six weeks, the spinal cord tumor and subcutaneous mass were grossly total resected; pathologic findings indicated an atypical myxoid spindle cell neoplasm, possibly nerve sheath in type. The final diagnosis of the mass was an atypical myxoid spindle cell neoplasm. The postoperative course was uneventful, and the patient was discharged after nine days without any neurological deficit. We report a rare case of an intradural extramedullary spinal tumor with subcutaneous mass in a neonate. It is necessary to monitor the patient's status by examining consecutive radiologic images, and the symptoms and neurological changes should be observed strictly during long-term follow-up.

폐 종괴로 나타난 원발성 골수섬유증 환자의 골수 외 조혈 1예 (A Case of Extramedullary Hematopoiesis Presenting as a Lung Mass in a Patient with Primary Myelofibrosis)

  • 김여명;김현태;노금엽;강민수;장윤환;김혜련;이재철;김철현
    • Tuberculosis and Respiratory Diseases
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    • 제67권3호
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    • pp.244-248
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    • 2009
  • Primary myelofibrosis is characterized by replacement of bone marrow with fibrotic tissue and the development of extramedullary hematopoiesis. Extramedullary hematopoiesis primarily involves the spleen and liver, but can also occur in the lungs. We report the case of an 80-year-old male who was admitted for evaluation of a lung mass and persistent thrombocytopenia. A percutaneous needle aspiration from the mass in the right lower lung showed myelopoietic cells with fatty tissue. A bone marrow biopsy revealed a hypercellular marrow with an increased number of atypical megakaryocytes. The final diagnosis was a prefibrotic stage of primary myelofibrosis leading to extramedullary hematopoiesis in the lung.

고령에서 발현한 척수외 혈관모세포종 - 증 례 보 고 - (Intradural Extramedullary Hemangioblastoma of the Spinal Cord in Old Age - A Case Report -)

  • 김영우;김재건;유도성;허필우;조경석;김달수;강준기
    • Journal of Korean Neurosurgical Society
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    • 제30권sup2호
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    • pp.361-363
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    • 2001
  • Intradural extramedullary hemangioblastoma of the spinal cord is uncommon tumor. Symptom onset is typically in the forth decade. Complete excision offers the best chance for cure. We report a case of extramedullary hemangioblastoma of the spinal cord in old age. A 76 -year old man presented with 1 month history of paraparesis. Multiple enhancing lower thoracic and lumbar spinal masses were seen on magnetic resonance imaging(MRI). Surgical exploration for symptomatic lesion revealed intradural-extramedullary mass, which had hypervascularity. The excised spinal masses were diagnosed as hemangioblastoma. Postoperative course was uneventful and symptoms improved gradually.

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척수 원위부에 발생한 경막내수막외 혈관아세포종 - 증례보고 - (An Intradural Extramedullary Hemangioblastoma of Distal Spinal Cord - A Case Report -)

  • 박성호;조준;윤승환;장상근
    • Journal of Korean Neurosurgical Society
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    • 제29권11호
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    • pp.1523-1526
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    • 2000
  • It has been known that hemangioblastoma of spinal cord occurs about 4% of all the spinal tumors. The authors present a rare case of intradural extramedullary(IDEM) hemangioblastoma of distal spinal cord in 41-year-old male patient. This IDEM mass at the level of conus medullaris showed iso-signal intensities on T1-weighted image(T1-WI) and high-signal intensities on T2-WI, and was enhanced homogeneously on MRI. At surgery, T12- L1 total laminectomy and enbloc mass removal were performed. This IDEM hemangioblastoma was confirmed by histopathologic findings. For less postoperative complication in IDEM tumors, we suggest that precise preoperative evaluation and complete excision via proper surgical approach to distal conus should be reemphasized.

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경막내 척수외 결핵종의 자기공명영상 소견: 2예 보고 (MR Imaging of Intradural Extramedullary Tuberculoma of the Spinal Cord: Report of Two Cases)

  • 손영준;최시성;전세정;박성훈;정선관
    • Investigative Magnetic Resonance Imaging
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    • 제12권2호
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    • pp.201-205
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    • 2008
  • 경막내 척수외 결핵종은 척추 결핵의 드문 형태로, 몇몇 증례들이 보고되었다. 저자들은 최근 흉추에 발생한 광범위한 경막내 척수외 결핵종 2예를 경험하였기에 문헌고찰과 함께 보고하고자 한다.

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Primary Extramedullary Ependymoma of the Cervical Spine : Case Report and Review of the Literature

  • Son, Dong-Wuk;Song, Geun-Sung;Han, In-Ho;Choi, Byung-Kwan
    • Journal of Korean Neurosurgical Society
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    • 제50권1호
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    • pp.57-59
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    • 2011
  • Intradural extramedullary (IDEM) ependymomas occur very rarely and little has been reported about their clinical characteristics. The authors present a case of a 57-year-old woman with an IDEM ependymoma. She was referred for the evaluation of a 4-month history of increasing neck pain and muscular weakness of the left extremities. Magnetic resonance imaging (MRI) of the cervical spine demonstrated an IDEM tumor with spinal cord compression. At the time of surgery, an encapsulated IDEM tumor without a dural attachment or medullary infiltration was noted, but the tumor capsule adherent to the spinal cord and root was left in place to minimize the risk of neurological sequelae. Histologic examination revealed a benign classic ependymoma. The post-operative course was uneventful and radiotherapy was performed. The patient showed an excellent clinical recovery, with no recurrence after 5 years of follow-up.

Herniated Lumbar Disc Combined with Spinal Intradural Extramedullary Cysticercosis

  • Choi, Kyeong-Bo;Hwang, Byeong-Wook;Choi, Won-Gyu;Lee, Sang-Ho
    • Journal of Korean Neurosurgical Society
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    • 제48권6호
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    • pp.547-550
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    • 2010
  • Spinal cysticercosis is a very uncommon manifestation of neurocysticercosis which is caused by the larvae of Taenia solium. However, it can develop as a primary infection through blood stream or direct larval migration. It can result in high recurrence and severe neurologic morbidity if not treated appropriately. We report the case of a 43-year-old woman who presented with severe lower back pain and left leg radiating pain in recent 2 weeks. Magnetic resonance image (MRI) of lumbar spine demonstrated extruded disc at the L5-S1 level combined with intradural extramedullary cystic lesion. We performed the open lumbar microdiscectomy (OLM) at L5-S1 on the left with total excision of cystic mass. After surgery, the patient showed an improvement of previous symptoms. Diagnosis was confirmed by histopathological examination as intradural extramedullary cysticercosis. We discuss clinical features, diagnostic screening, and treatment options of spinal cysticercosis.

Neurologic Complication Following Spinal Epidural Anesthesia in a Patient with Spinal Intradural Extramedullary Tumor

  • Kim, Sung-Hoon;Song, Geun-Sung;Son, Dong-Wuk;Lee, Sang-Won
    • Journal of Korean Neurosurgical Society
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    • 제48권6호
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    • pp.544-546
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    • 2010
  • Paraplegia following spinal epidural anesthesia is extremely rare. Various lesions for neurologic complications have been documented in the literature. We report a 66-year-old female who developed paraplegia after left knee surgery for osteoarthritis under spinal epidural anesthesia. In the recovery room, paraplegia and numbness below T4 vertebra was checked. A magnetic resonance image (MRI) scan showed a spinal thoracic intradural extramedullary (IDEM) tumor. After extirpation of the tumor, the motor weakness improved to the grade of 3/5. If a neurologic deficit following spinal epidural anesthesia does not resolve, a MRI should be performed without delay to accurately diagnose the cause of the deficit and optimal treatment should be rendered for the causative lesion.

Extramedullary tanycytic ependymoma of the lumbar spinal cord

  • Kim, Dong Ja;Han, Man-Hoon;Lee, SangHan
    • Journal of Yeungnam Medical Science
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    • 제37권2호
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    • pp.128-132
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    • 2020
  • Tanycytic ependymoma is a rare variant of ependymoma that commonly affects the cervical and thoracic spinal cord. It usually arises as intramedullary lesions, and extramedullary cases are extremely rare. We report a case of a 44-year-old woman who was diagnosed with tanycytic ependymoma in her lumbar spine at level 2-3. The tumor mass developed in an intradural extramedullary location. Histopathologically, tanycytic ependymoma can be misdiagnosed as schwannoma or pilocytic astrocytoma. Immunohistochemical findings such as strong positivity for glial fibrillary acidic protein, perinuclear dot-like positive patterns for epithelial membrane antigen, and focal positivity for S100 protein are helpful in diagnosing tanycytic ependymoma. It is important to be aware of this rare tumor to ensure appropriate patient management and accurate prognosis.

Endoscopic Diagnosis and Management of Esophageal Extramedullary Plasmacytoma in a Dog

  • Tae-Hyung Kwon;Guk-Il Jung;Kun-Ho Song;Joong-Hyun Song
    • 한국임상수의학회지
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    • 제41권1호
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    • pp.18-23
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    • 2024
  • A 13-year-old spayed female Golden Retriever with clinical signs of weight loss and lethargy presented with two esophageal masses and one sessile polyp on computed tomography and esophagoscopy. Endoscopic snare resection was performed, and histopathological examination was requested. Based on histopathology and immunohistochemistry of multiple myeloma oncogene 1 staining, the patient was diagnosed with esophageal extramedullary plasmacytoma. The patient remained clinically well without any clinical signs during a follow-up period of 12 months. Herein, we report the successful diagnosis and management of esophageal extramedullary plasmacytoma in a dog using endoscopy.