• 제목/요약/키워드: Expression characteristics

검색결과 2,607건 처리시간 0.031초

Lack of any Prognostic Relationship between Adiponectin Receptor (Adipo R1/R2) Expression for Early/Advanced Stage Gastric Cancer

  • Ayyildiz, Talat;Dolar, Enver;Ugras, Nesrin;Dizdar, Oguzhan Sitki;Adim, Saduman Balaban;Yerci, Omer
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권11호
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    • pp.4711-4716
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    • 2014
  • Introduction: Adiponectin (ApN) is a complement C1q-related protein, mainly secreted from adipose tissue, that signals through ApN receptor1 (Adipo-R1) and ApN receptor 2 (Adipo-R2). Low serum ApN concentrations are associated with obesity-related malignancies. However, there are very few studies on any prognostic role of ApN receptors in gastric cancer. Objectives: The aim of this study is to investigate the relationship between AdipoR1/R2 expression and early/advanced stage gastric cancer in terms of clinicopathologic characteristics and survival. Materials and Methods: Eighteen patients with early and 39 with advanced stage gastric cancer who underwent surgical gastric resection were included in this study. Results: Adipo-R1 expression was low in 2 of the 18 patients with early stage gastric cancer (11.1%), while 4 had low Adipo-R2 expression (22.2%). In those with advanced stage gastric cancer, 7 of 39 had low Adipo-R1 expression (17.9%) and 16 had low Adipo-R2 expression (41%). Adipo-R2 expression was significantly higher (p=0.011) in moderately differentiated tumors when compared to well-differentiated tumors. While there was nearly a statistically significant relationship between TNM stage (T, tumor size; N, regional lymph node; M, whether distant metastases exist) and Adipo-R2 expression (p=0.054), there was no relationship between Adipo-R1/-R2 expression with tumor stage and survival. Conclusion: Adipo-R1/-R2 expression has no prognostic significance of in early/advanced stage gastric cancer.

Analysis of Indoleamine 2-3 Dioxygenase (IDO) and EGFR Co-expression in Breast Cancer Tissue by Immunohistochemistry

  • Bi, Wei-Wei;Zhang, Wei-Hua;Yin, Gui-Hua;Luo, Hong;Wang, Shou-Qin;Wang, Hongran;Li, Chao;Yan, Wei-Qun;Nie, De-Zhi
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권14호
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    • pp.5535-5538
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    • 2014
  • Background: To determine the amount of co-expression of IDO and EGFR in breast cancer patients. Materials and Methods:In order to obtain the distribution of co-expression of IDO and EGFR in breast cancer, we tested 110 breast cancer paraffin tissue blocks with immunohistochemical methods. Then we investigated the relationship between the diagnostic and pathologic characteristics (tumor size, lymph node status, histologic grade, the gene expression of ER, PR, HER2, p53, Ki67 and PCNA) with the situation of co-expression of IDO and EGFR by reviewing the medical records of 32 breast cancer patients. Results: Among 110 breast cancers, 32 cases demonstrated IDO and EGFR co-expression (29.1%), IDO and EGFR synchronous co-expression being found in 19.1% and asynchronous in 10.0%. Conclusions: IDO and EGFR were co-expressed in breast cancer, including synchronous and asynchronous co-expression. The results suggest that considering IDO and EGFR as two indicators for breast cancer treatment or prognosis analysis provides a potential option of individual treatment for the portion of breast cancer patients with co-expression of IDO and EGFR.

스페이스 브랜딩을 적용한 한식뷔페 표현특성 - 서울시에 위치한 한식뷔페를 중심으로 - (Expression Characteristics of Korean Buffet applied Space Branding - Focusing on the Korean Buffet in Seoul City -)

  • 정영현
    • 한국실내디자인학회논문집
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    • 제26권3호
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    • pp.91-100
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    • 2017
  • The rapid growth of Korean-style buffet in recent years has increased the size of corporate investment. Under this circumstance, businesses make various marketing efforts while highlighting the features and advantages of their brands. Against this backdrop, this study aims to understand which space branding has been applied to the Korean-style buffet through case studies and to propose a method of application of space branding to increase sales in an effective manner in the future. First, the research is theoretical examination and case studies with focus on the characteristics of expressions of Korean-style buffet space branding. Basically, upon completion of examining the concept and the characteristics of expressions of the Korean-style buffet and analyzing the concept of space branding, the components of space branding have been reconstructed based on preceding studies on space branding and then have been applied to each brand space. Also, the hands-on experience of the characteristics of expression of the Korean-style buffet with space branding incorporated in it and prepared a checklist via visual inspections. And then, the field surveys based on these examinations and took approach of drawing a conclusion based on the results analysis conducted by using the SPSS statistical program. Through preceding studies, the three components of space branding, that is, sensory element, emotional element, and cognitive element have been reconstructed before proceeding with this study, which has obtained five major findings as a conclusion. First, the sensory element should be given elements differentiated enough to attract consumers' attention along with a sustainable effort to have brand image imprinted in their mind. Second, in terms of emotional element, the study has found that the brand experience oriented toward interest and participation results in higher utility frequency. Third, the study has found that the cognitive element should seek consistency in communicating with consumers with focus on face-to-face contact on the display in space. Fourth, it has been found that arranging independent spaces is necessary to attract consumers' participation. Finally, the study has identified in which location area of buffet the sensory, emotional, and cognitive elements have placed a significant weight.

영화 '이상한 나라 앨리스'의 영화의상에 나타난 환상성의 표현 유형에 관한 연구 - 문학적 환상성 이론을 중심으로 - (A Study on Expression Types of Fantasy in Movie Costumes for 'Alice In Wonderland' - Focused on the Theory of Fantasy in Literature -)

  • 김장현;김영삼
    • 한국의류산업학회지
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    • 제16권1호
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    • pp.26-34
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    • 2014
  • This study considered movie costumes shown in 'Alice In Wonderland' by Tim Burton based on the Theory of Fantasy in Literature by Tzvetan Todorov and Rosemary Jackson. The research method used was a case study on expression types of fantasy used in movie costumes with a literature research based on the Theory of Fantasy in Literature. The Theory of Fantasy in Literature has significance in suggesting a new theoretical approach for understanding a visual perspective and aesthetic characteristics shown in fashion as well as movie costumes. The conclusions of the study are as follows. First, fantasy can connote characteristics of the marvelous, the uncanny, and the imitative through a consideration of Theory of Fantasy in Literature. Second, the marvelous is what is not beautiful, not ugly, but is strange and surprising, and what escapes from the existing norm. The characteristics of the marvelous in movie costumes are expressed through cross-dressing or displayed by allowing the personified animal to wear clothes. Third, the uncanny is something that causes grotesque, disgusting, comic and recreational responses. The characteristics of the uncanny in movie costumes are expressed through exaggerating and artificially transforming the body. Fourth, the imitative is the property of trying to imitate or follow other things. The characteristics of the imitative in movie costumes are indicated by dismantling and expanding a form through borrowing costumes from various ages.

The relationship between myofiber characteristics and meat quality of Chinese Qinchuan and Luxi cattle

  • Lu, Xiao;Yang, Yuying;Zhang, Yimin;Mao, Yanwei;Liang, Rongrong;Zhu, Lixian;Luo, Xin
    • Animal Bioscience
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    • 제34권4호
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    • pp.743-750
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    • 2021
  • Objective: The objectives of this study were to explore the expression patterns of myosin heavy chain (MyHC) genes of different skeletal muscles from Chinese cattle, and to investigate the relationship between myofiber characteristics and meat quality of M. longissimus lumborum (LL), M. psoas major (PM), and M. semimembranosus (SM) from Chinese Luxi and Qinchuan cattle. Methods: Three major muscles including LL, PM, and SM from Chinese Luxi cattle and Chinese Qinchuan cattle were used in this study. The myofiber characteristics were measured by histochemical analysis. The MyHC isoforms expression was evaluated by real-time quantitative polymerase chain reaction. Quality traits including pH value, meat color, cooking loss, Warner-Bratzler shear force (WBSF) and sarcomere length were determined at day 5 postmortem. Results: PM muscle had higher pH value, a* value, sarcomere length and lower WBSF value compared to LL and SM muscles (p<0.05). Numbers of type I myofiber and the relative expression of MyHC I mRNA in PM muscle were higher than those of LL and SM muscles (p<0.05). Myofiber diameter of PM muscle was lower than that of LL and SM muscles, regardless of myofiber types (p<0.05). Conclusion: According to the stepwise linear regression analyses, tenderness was influenced by myofiber characteristics in all three examined muscles. Tenderness of beef muscles from Qinchuan and Luxi cattle could be improved by increasing numbers of type I myofiber.

Expression of Low Voltage-Activated $Ca^{2+}$ Channels in Xenopus Oocytes

  • Lee, Jung-Ha;Han, Dong-Pyo
    • Journal of Microbiology and Biotechnology
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    • 제11권4호
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    • pp.614-618
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    • 2001
  • Low-threshold T-type $Ca^{2+}$ channels are distinctive voltage-operated gates for external $Ca^{2+}$ entry around a resting membrane potential due to their low voltage activation. These phenomena have already been extensively studied due to their relevance in diverse physiological functions. Recently, three T-type $Ca^{2+}$ channel ${\alpha}$$_1$subunits were cloned and their biophysical properties were characterized after expression in mammalian expression systems. In this study, ${\alpha_IG} and {\alpha_IH}$ low-threshold $Ca^{2+}$ channels were expressed and characterized in Xenopus oocytes after adding 5' and 3'untranslated portions of a Xenopus ${\beta}$ globin to improve their expression levels. The added portions dramatically enhanced the expression levels of the ${\alpha_IG} and {\alpha_IH}$ T-type channels. When currents were recorded in 10 mM $Ba^{2+}$ as the charge carrier, the activation thresholds were about -60 mV, peak currents appeared at -20 mV, and the reversal potentials were between +40 and +45. The activation time constants were very similar to each other, while the inactivation time constants of the ${\alpha_IG}$ currents were smaller than those of ${\alpha_IH}$. Taken together, the electrophysiological properties of the ${\alpha_IG} and {\alpha_IH}$ channels expressed in Xenopus oocytes were similar to the previously reported characteristics of low-threshold $Ca^{2+}$ channel currents.

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현대 패션디자인에 표현된 새 이미지 연구 (A Study on the Bird Image Expressed in Modern Fashion Design)

  • 안세라;금기숙
    • 복식문화연구
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    • 제19권6호
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    • pp.1177-1192
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    • 2011
  • As a free creature that can fly in the sky, the bird has been an object of admiration and mystery and a mediator between human beings and the heavens. This study aims to clarify the aesthetic value of birds through study of the various expressions of the bird image on clothing and by the formative will of designers. Based on the general examination of the bird image through the study of documents, this study is composed of a case analysis, which reveals on modern fashion designs. Additionally, the forms of expression of the bird image are organized according to the stereoscopic expression of shaping, the relief expression of handicraft decoration, the flat expression of surface design, and the characteristic expression of wings and feathers. The aesthetic characteristics revealed by the expression patterns are metaphorical symbolism, surrealistic humor, lyrical naturalness, and fantastical femininity. Since antiquity, the bird image continuously recreated by artists has offered aesthetic value in terms of formativeness in the external form and symbolism in the internal form. This study would help to understand the diversity of creation in contemporary fashion design.

HRI를 위한 사람의 내적 요소 기반의 인공 정서 표현 시스템 (Human emotional elements and external stimulus information-based Artificial Emotion Expression System for HRI)

  • 오승원;한민수
    • 한국HCI학회:학술대회논문집
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    • 한국HCI학회 2008년도 학술대회 1부
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    • pp.7-12
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    • 2008
  • 사람과 로봇의 인터랙션에 있어 정서의 역할은 중요하다. 그러므로 사람과 유사한 정서 메커니즘이 로봇에게 필요하다. 본 논문에서는 사람의 정서에 대한 심리적 연구를 바탕으로 사람의 내적 요소에 기반한 새로운 인공 정서 표현 시스템을 제안한다. 제안된 시스템은 external stimulus, emotion, mood, personality, tendency, machine rhythm 의 6가지 정보 요소를 활용하며, 각 요소들은 그들의 특성에 따라 결과적으로 emotion 표현 패턴의 변화에 영향을 준다. 그 결과 통일한 외부 자극들은 내적 상태에 따라 emotion의 변화를 만들어 낸다. 제안된 시스템은 사람과 로봇의 자연스러운 인터랙션을 유지하고, 친밀한 관계를 형성할 수 있도록 도움을 줄 것이다.

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패션 일러스트레이션에서의 사진 이미지 차용에 관한 연구 (A Study on the Photo-image Appropriation in Fashion Illustration)

  • 김순자
    • 한국의류학회지
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    • 제33권7호
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    • pp.1061-1073
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    • 2009
  • Present expression methods have close relations with popular culture in the active acceptance of various kinds of genre. Fashion illustration is no longer limited to sketching garments or technically explaining construction, it is accepted as an art that is expressed by the desire and consciousness of the artist. This study examines the expressional characteristics and effects of photo-image appropriation as an expression method in fashion illustration. The word 'appropriation' (to steal something) is used as euphemism and not meant to be derogatory. The methods of appropriation in art indicate that paintings are not inventions but are self-satisfactory creations that show that the idea of originality is false and that paintings should be uninhibited from the greed of the authority of the genius of artists. In postmodern paintings, the photo-image of appropriation are expressed through the methods of re-photography, photo collage, and photo painting. Photo-image appropriation methods in fashion illustration are re-photography, photo collage, image mixing of photography, drawing, and graphic expression of photography. Fashion illustrators are able to develop expression techniques for expanding a field of expression and enhance the ability of communication through the photo-image appropriation methods.

현대 실내디자인의 하이브리드 미학적 표현기법과 특성에 관한 연구 (A Study on the Expression Techniques and Characteristic of Hybrid Aesthetics in Contemporary Interior Design)

  • 김은지;이정욱
    • 한국실내디자인학회논문집
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    • 제16권1호
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    • pp.39-47
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    • 2007
  • In comtemporary interior design, hybrid form causes cognitive turnovers of aesthetics. Especially it offers much possibility to expression techniques in interior design and works as compound system, symbolic aggregate that makes and expands various meanings. The aesthetic ideology of hybrid design can be interpreted through the philosphic concept of art, sublime, reception, representation and explains expression techniques and characteristic in interior design through various transformation and meaning conversion. The expression techinique that is a form of openness, transcendental interpretation that exceed a dupilicate of meaning. can be classified as oxymoron, defamiliarization and interface. The characteristic that is based on those expressions appears as use of complex codes of visual images, decoding strategy, intertextuality of meaning. This research attitude can explain the thinking method of interior design by defining the epistemological scheme that is basically involved in expressional styles with characteristics of hybrid aesthetics. In order to be recognized as the object of aesthetics, hybrid has to be approached by interpretational methods of expression techniques. Consequently the characters of expression techniques in hybrid design can be investigated as one of the methodology in interior design plan.