• 제목/요약/키워드: Exposure Periods

검색결과 262건 처리시간 0.033초

실험실 근무자의 화학물질 노출과 건강 위험 (A Review on Chemical Exposure and Related Health Risks in Laboratory Workers)

  • 변혜정;박정임
    • 한국환경보건학회지
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    • 제36권6호
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    • pp.441-455
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    • 2010
  • Researchers who work in science and engineering R&D laboratories are commonly exposed to a wide range of chemical, biological and physical hazards. They also may adopt ergonomically poor postures for long periods of time. These factors may increase the risk of adverse health outcomes in laboratory workers. Recently, there were several fatal accidents in the laboratories in universities and research institutes in Korea. Consequently, the 'Laboratory Safety Act' was enacted in 2006. However, there are concerns about the health risk associated with chronic exposures to hazards, as the management measures provided in this Act are very limited, focusing primarily on accident prevention and compensation for lab work-related accidents. In this article, the methods for assessing exposure to chemicals in laboratory environments are discussed. Also, epidemiological studies examining the association between laboratory exposure and health effects, including cancer and reproductive toxicity are extensively reviewed. Finally, the possible roles of environmental health professionals in this area are suggested, along with a list of critical research needs for properly assessing laboratory workers' exposure and risk.

시나리오별 논에서의 molinate 노출위험도 분석: (2) 노출위험도 평가 (Scenario-Based Exposure Risk Assessment of Molinate in a Paddy Plot ; (2) Exposure Risk Assessment)

  • 박기중;정상옥
    • 한국농공학회논문집
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    • 제50권4호
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    • pp.17-24
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    • 2008
  • Exposure risk assessment of pesticide molinate using the RICEWQ model in a rice paddy plot was performed to observe the effects of various water and pesticide management scenarios. Several scenarios were developed to represent the specific water and pesticide management practices of rice cultivation in Korea. The results of the scenario analysis using the RICEWQ model simulation from the previous studies were analysed. The molinate risk for aquatic organisms is evaluated by the ratio of the predicted environmental concentration(PEC) and the predicted no-effect concentration(PNEC). The results showed that the no-effect periods for aquatic organisms for the deep, shallow and very shallow irrigation conditions were 33.3, 28.9 and 25.6 DATs for the lable rate application and 36.4, 33.7 and 30.8 DATs for the double lable rate application, respectively. The higher application rate showed greater exposure risk to the aquatic organisms. Based on this study, the withholding period of molinate practiced in Korea, that is 3 to 4 DATs, must be much longer. The results of this study can be used for the non-point source pollution control and environmental policy making regarding pesticides.

Effects of harsh environmental exposures on the bond capacity between concrete and GFRP reinforcing bars

  • Al-Tamimia, Adil;Abed, Farid H.;Al-Rahmani, Abdulla
    • Advances in concrete construction
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    • 제2권1호
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    • pp.1-11
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    • 2014
  • This paper demonstrates an experimental study to evaluate the effects of environmental exposures on the bond between ribbed Glass Fiber Reinforced Polymer (GFRP) reinforcing bars and concrete. The equation recommended by ACI 440-1R-06, for the bond stress,was evaluated in this study. A total of 16 pullout samples, 12with GFRP bars and 4with steel bars, were exposed to two different harsh environments for different periods of time. The exposed harsh environments included direct sun exposure and cyclic splash zone sea water. The variation in the shear (bond) strengths before and after exposure was considered as a measure of the durability of the bond between GFRP bars and concrete.Experimental results showed there is no significant difference of the bond strength between 60 and 90 days of exposures.It also showed that the empirical equation of the bond stress calculated by ACI 440-IR-06 is very conservative.

황백, 연교 및 감초 추출물을 이용한 국소제제의 Staphylococcus intermedius에 대한 항균효과 (Antibacterial Activity of Topical Agent Extracted from Phellodendri cortex, Forsythia fructus and Glycyrrhizae radix Against Staphylococcus intermedius in Dogs)

  • 정효훈;오태호
    • 한국임상수의학회지
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    • 제22권4호
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    • pp.353-356
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    • 2005
  • This study was performed to examine the antibacterial efecacy of topical agent extracted from Phellodendri cortex, Forsythia fructus and Glycyrrhizae radix as an alternative dermatological agent. Also, the most efficacious concentration of this agent and the skin-contact time inhibiting the vegetation of bacterial cells in various dilutions were determined. Five strains of Staphylococcus intermedius were exposed to various dilutions of this agent. The efficacy was assessed after exposure for time periods varying between 0 and 30 min. The antibacterial efficacy was shown to be the strongest at dilution of 1: 2. The number of viable organisms decreased significantly after 8 minutes of exposure time and was the smallest after 30 minutes of exposure time. This alternative dermatological agent is considered to be effective against Staphylococcus intermedius and has a potential to be a new topical agents far the treatment of pyoderma in dogs.

3.5 중량% NaCl 용액에서 쌍선 아크 용사 공정으로 증착된 Al-Zn 코팅의 부식 성능에 대한 기공 밀봉제로서의 헥사메타인산나트륨의 영향 (Effect of sodium hexa-meta phosphate as pore-sealing agent on the corrosion performance of Al-Zn coating deposited by twin-wire arc thermal spray process in 3.5 wt.% NaCl solution)

  • 지텐드라 쿠마 싱;잔낫;이한승
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2022년도 가을 학술논문 발표대회
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    • pp.81-82
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    • 2022
  • Al and Zn are used to protect the steel structures from corrosion. In the present studies, 15Al-85Zn alloy wires has been used for the deposition of coating by arc thermal spray process. Moreover, this process of coating exhibited severe defects formation, therefore, this coating was post-treated with different concentrations i.e. 0.05, 0.1 and 0.5M sodium hexa meta phosphate (Na6[(PO3)6]: SHMP) to fill to defects of deposited coatings and assessed their corrosion resistance in 3.5 wt.% NaCl solution with exposure periods. After the treatment, the porosity of the coating reduced significantly by formation of composite oxide films onto the coating surface. Initially, 0.5 M SHMP treated coating exhibited highest in total impedance due to significant reduction of porosity but once the exposure periods are extended, the composite oxides are dissolved, thus, total impedance is decreased.

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카드뮴 장기노출에 따른 넙치, Paralichthys olivaceus의 기관별 축적 (Cadmium Accumulation in Tissue of Olive Flounder, Paralichthys olivaceus During tong Term Exposure)

  • 장석우;김성길;강주찬
    • 한국수산과학회지
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    • 제35권5호
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    • pp.480-484
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    • 2002
  • 넙치 (Paralichthys olivaceus)를 카드뮴 아치사 농도인 5, 10, 50, 100$\mu$g/L의 구간에 노출시켜 30일 동안 아가미, 간, 신장, 창자에서 축적되는 정도를 조사하였다. 넙치에서 카드뮴의 축적은 아가미, 창자와 간에서 카드뮴의 노출농도와 노출기간에 따라서 증가를 하였으며, 그러한 양상은 선형적으로 증가를 하였다 노출 20일까지는 기관별 축적순서는 아가미>간>창자>신장의 순서로 나타나지만, 노출 30일 이후에는 아가미와 간에서 축적이 완만한 경향을 나타내며, 창자의 축적은 급격한 경향을 나타내어 기관별 축적순서는 창자>아가미>간>신장의 순서로 나타났다. 카드뮴의 넙치에 대한 축적계수는 아가미와 신장, 창자에서 노출농도에 반비례하며, 노출 시간에 따라 증가하는 경향을 나타났다.

Changes in Antioxidant Enzyme Activities in the Gill And Digestive Glands of the Manila Clam Ruditapes philippinarum exposed to Cu

  • Min, Eun-Young;Jang, Suck-Woo;Kim, Sung-Gil;Kang, Ju-Cban
    • Fisheries and Aquatic Sciences
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    • 제13권1호
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    • pp.71-78
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    • 2010
  • We investigated the effect of Cu exposure on the activities of protective antioxidant enzymes in the gills and digestive glands of the manila clam Ruditapes phillippinarum exposed to subchronic concentrations (0, 20, 40, and $80{\mu}gL^{-1}$) of waterborne Cu. No mortality occurred during the experimental period, and no significant condition index differences were observed in any exposure group compared with the control. No significant differences were observed in the digestive glands and gills of the clams observed during 15 days of exposure, but after 30 days, the SOD activity in the gill showed a significant difference between the $80{\mu}gL^{-1}$ Cu-exposed group and the control. GPx activities in the digestive glands and gills were significantly lower after 30 days of Cu exposure. Gill GR activity in the high-exposure group ($80{\mu}gL^{-1}$) was significantly elevated compared with that in the control group. GST activities in the digestive glands of all groups did not change over 30 days. However, GST activity in the gill at $80{\mu}gL^{-1}$ Cu was significantly higher after 15 and 30 days of exposure. GSH activities in the gill showed patterns similar to those of GST activities during exposure periods. In the digestive glands, GSH activity was higher only at $80{\mu}gL^{-1}$ after 30 days exposure. In digestive glands and gills, the MDA levels of clams exposed to $80{\mu}gL^{-1}$ Cu were significantly higher after 30 days of exposure.

Effects of the exposure site on histological pulpal responses after direct capping with 2 calcium-silicate based cements in a rat model

  • Trongkij, Panruethai;Sutimuntanakul, Supachai;Lapthanasupkul, Puangwan;Chaimanakarn, Chitpol;Wong, Rebecca;Banomyong, Danuchit
    • Restorative Dentistry and Endodontics
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    • 제43권4호
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    • pp.36.1-36.12
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    • 2018
  • Objectives: Direct pulp capping is a treatment for mechanically exposed pulp in which a biocompatible capping material is used to preserve pulpal vitality. Biocompatibility tests in animal studies have used a variety of experimental protocols, particularly with regard to the exposure site. In this study, pulp exposure on the occlusal and mesial surfaces of molar teeth was investigated in a rat model. Materials and Methods: A total of 58 maxillary first molars of Wistar rats were used. Forty molars were mechanically exposed and randomly assigned according to 3 factors: 1) the exposure site (occlusal or mesial), 2) the pulp-capping material (ProRoot White MTA or Bio-MA), and 3) 2 follow-up periods (1 day or 7 days) (n = 5 each). The pulp of 6 intact molars served as negative controls. The pulp of 12 molars was exposed without a capping material (n = 3 per exposure site for each period) and served as positive controls. Inflammatory cell infiltration and reparative dentin formation were histologically evaluated at 1 and 7 days using grading scores. Results: At 1 day, localized mild inflammation was detected in most teeth in all experimental groups. At 7 days, continuous/discontinuous calcified bridges were formed at exposure sites with no or few inflammatory cells. No significant differences in pulpal response according to the exposure site or calcium-silicate cement were observed. Conclusions: The location of the exposure site had no effect on rat pulpal healing. However, mesial exposures could be performed easily, with more consistent results. The pulpal responses were not significantly different between the 2 capping materials.

자동차 조립공정에서 공기압력식 진동공구의 국소진동평가 (Assessment of Vibration Produced by Pneumatic Hand Tools Used in Automobile Assembly)

  • 김선술;백남원
    • 한국산업보건학회지
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    • 제6권1호
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    • pp.1-16
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    • 1996
  • This study was conducted at an automobile assembly line located in Kyonggi-do, Korea from January 16 to February 28, 1995. The purposes of this study were to assess worker exposures to hand-arm vibration and the performance of gloves for reduction of vibration. The exposure to vibration was measured using to the ISO 5349(1986) method. Vibration acceleration and frequency spectra for each tool were determined on-line replicating actual working conditions and analyzed together with exposure time for evaluating individual worker exposure. Eight pneumatic hand tools, 60 workers exposured to hand-arm vibration, and three pairs of gloves were involved in this study. Results are summarized as follows. 1. Dominant frequencies of vibration for all tools(n=8) measured in this study ranged from 250 Hz to 800 Hz. 2. There was no significant correleration between dominant frequencies and free running speed (p>0.05). 3. Total predicted exposure times of using impact, hammer type did not exceed 40 minutes, but metal finish task, using grinder and sander exceeded 40 minutes. Total exposure time affected significantly the frequency-weighted, 4 hr equivalent acceleration. 4. Predicted prevalence and observed exposure period data were compared in workers(n=60), according to ISO 5349. In this results, 23(50.0 %) and 24(48.07 %) persons exceeded the mean latency periods for vibration-induced white finger(VWF) at 10 % (n=46) and 50 % (n=52) standards, respectively. On the basis of ISO equation, mean latent periods for VWF were 3.23, 4.72 years at 10 %, 50 % standards, respectively. 5. Reduction of vibration by gloves was evaluated. Since impact pneumatic tools produced low frequency vibrations, conventional gloves did not provide any protection. Gloves A and C amplify somewhat the signal at frequency below 400 Hz; the attenuation increases progressively by frequency to reach 18 dB ($7.94{\times}10^{-6}m/s^2$) at 1,000 Hz, slightly worsening Glove B did not provide any protection and made the situation slightly worse. However, since they make the hands warm, the occurrence of vibration-induced white fingers may be reduced.

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Changes in Mechanical Properties of Wood Due to 1 Year Outdoor Exposure

  • KIM, Gwang-Chul;KIM, Jun-Ho
    • Journal of the Korean Wood Science and Technology
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    • 제48권1호
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    • pp.12-21
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    • 2020
  • For quantitative evaluation of wooden structures, the mechanical performance of members has undergone outdoor exposure tests. A year-long monitoring was conducted using an SPF species. Test groups were divided into twelve (each month) to measure the moisture content, density and ultimate load. Starting from May when moisture content of the test group was at the lowest, simple failure modes were observed more frequently during the first half of the experiment, whereas complex failure modes took over during the second half. Starting from June when moisture content of the test group was the highest, ultimate load decreased by 30% in the second half compared to the first half. A multiple regression analysis confirmed that moisture content of the test group was the variable with most effect on ultimate load of various outdoor variables, and an estimation equation of a simple regression analysis revealed that moisture content and ultimate load formed an inversely proportionate relationship. It is thought that correlational relationships of variables other than moisture content could be applied with the increase in added data amount by longer periods of outdoor exposure tests.