Objective: The purpose of this study is to find out whether people still have problems with breathing after being quarantined for a certain period after being infected with COVID-19. Design: Two-group pretest-posttest design. Methods: A total of 36 subjects were included in this study. Subjects who have been quarantined after being infected with COVID-19 (the after-quarantine group, n=18) and those who have never had COVID-19 (the healthy group, n=18). Respiratory function was evaluated by subjects in resting state and after treadmill exercise. Subjects performed treadmill exercise at moderate intensity for 20 minutes. To compare the differences in respiratory function between groups, forced vital capacity (FVC), forced expiratory volume in first second (FEV1), and maximum voluntary ventilation (MVV) were evaluated using a spirometer. Results: The result of the study, there was a significant difference in FVC in the after-quarantine group between resting and after treadmill exercise (p<0.05). In the healthy group, there was no significant difference in respiratory functions between resting and after treadmill exercise. Conclusions: The meaning of this result is that people who have been quarantined with COVID-19 have lower respiratory function than healthy people who are not infected with COVID-19.
Background: The purpose of this study was to investigate the effects of breathing training on the balance ability, lung capacity, and shooting score of shooting athletes. Design: Randomized controlled trial. Methods: Twenty shooters were randomly assigned to the experimental group and the control group. Both the experimental group and the control group performed trunk stabilization exercise, and the experimental group received breathing training during exercise. Balance ability, lung capacity, and shooting score were measured before and after the intervention. Results: There was a significant difference in the forced expiratory volume at one second(FEV1), forced vital capacity(FVC) before and after intervention in the experimental group. In the comparison between the two groups, there was a significant difference in FVC between the control group and the control experimental group. Conclusion: The application of breathing training was effective in improving the lung capacity of shooters.
Purpose: This study investigated the effect of virtual reality and Schroth breathing exercises on the lung function characteristics of normal adults in their 20s. Methods: The subjects were randomly divided into groups with ten people each in the experimental groups, namely the virtual reality breathing exercise group (BBEG) and the Schroth breathing exercise group (SBEG), and the control group. The experimental groups performed each breathing exercise for 4 weeks. Subsequently, pulmonary function test indicators such as the forced vital capacity (FVC) and the forced expiratory volume (FEV1) were measured. Results: In the within-group comparison of the subjects before and after the exercises, there was a significant difference in the FVC and FEV1 (p<0.05), but there was no significant difference in FEV1/FVC. The result of the difference test between groups showed that there was a significant difference in FEV1/FVC after exercise (p<0.05). However, there were no significant differences in the remaining items (p>0.05). Conclusion: Improvement in lung function was seen in both exercise groups, and the changes in FEV1/FVC indicated significant improvement in the lung function of the experimental groups compared to the control group.
To evaluate training effect, aerobic dance was performed by eight female collegestudents for 8 weeks. Body composition, cardiopulmonary function at rest and during maximal exercise, blood cholesterol concentration at rest were determined before and after 8weeks of aerobic dance training. Maximal exercise was performed on the treadmill according of Bruce protocol. Pre to post training differences were evaluated. The results obtained were as follows : 1. After the training, skinfold thickness and total body fat decreased significantly(p<0.1) while lean body mass increased with significance (p<0.1). 2. Heart rate and arterial blood pressure at rest decreased without sinificance after the training. 3. As a result of training, forced vital capacity and forced expiratory volume for a second increased significantly (p<0.01, p<0.1). 4. After the training period, heart rate at 3, 6, and 9 min. during treadmill exercise was significantly lower than those of pretraining (p<0.05). 5. After the training, systolic and diastolic blood pressure at 6 and 9 min during the exercise was significantly lower than those of pretraining (p<0.025, p<0.1). 6. After the training, oxygen uptake at 3 and 6 min during the exercise was significantly greater than those of pretraining (p<0.05). 7. As a result of training, the maximal oxygen uptake increased significantly during the exercise (p<0.1). 8. After the training, expired air volume for a minute at 3 and 6 min during the exercise was signigicantly grerter than those of pretraining (p<0.1). 9. After the training, repiratory quotient during the exercise was lower than pretaining without significance. 10. After the training, blood HDL -cholesterol concentration incereased with significance, (p<0.1) blood total cholesterol and triglycerids concentration decreasedsignificantly (p<0.1). From these results, it may be concluded that 8 week aerobic dance training reduces skinfold thickness and body fat contents, improves the cardiopulmonary function and tissue oxygen utilization, reduces blood cholesterol and triglyceride concentration and brings about the increase of blood HDL-cholesterol concentriation.
Purpose: To evaluate the predictive factors of radiation pneumonitis (RP) and associated changes in pulmonary function after definitive concurrent chemoradiotherapy (CCRT) in patients with non-small cell lung cancer (NSCLC). Materials and Methods: Medical records of 60 patients with NSCLC who received definitive CCRT were retrospectively reviewed. Dose volumetric (DV) parameters, clinical factors, and pulmonary function test (PFT) data were analyzed. RP was graded according to the CTCAE ver. 4.0. Percentage of lung volume that received a dose of threshold (Vdose) and mean lung dose (MLD) were analyzed for potential DV predictors. PFT changes were calculated as the difference between pre-RT and post-RT values at 3, 6, and 12 months after RT. Results: Twenty-two patients (37%) developed grade ${\geq}2$ RP. Among clinical factors, tumor location in lower lobe was associated with RP. Among the DV parameters, only MLD >15 Gy was associated with grade ${\geq}2$ RP. There were statistically significant decreases in PFT at all points compared with pre-RT values in grade ${\geq}2$ RP group. MLD was associated with forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1) changes at 6 and 12 months. V10 was associated with FVC changes at 12 months. V20 and V30 were associated with FEV1 changes at 6 months and FVC changes at 12 months. Conclusion: After definitive CCRT in patients with NSCLC, MLD >15 Gy and lower lobe tumor location were predictors of grade ${\geq}2$ RP. Pulmonary functions were decreased after CCRT and the magnitude of changes was associated with DV parameters.
Background: A lung bulla may rarely shrink as a result of an inflammation within the bulla or a closing of a bronchus involved in the inflammation process, which is termed 'autobullectomy'. The purpose of this study was to describe clinical features of patients with regressions of bullae during follow-up. Methods: We retrospectively reviewed the cases and individuals who showed unequivocal evidence of interval regressions in a pre-existing bulla. A total of 477 cases with a bulla >5 cm in diameter were screened manually. Thirty cases with bullae that showed regression during follow-up were selected. Results: Regressions of large bullae occurred in 30 of 477 cases (6.3%). The median age of those patients was 61 (range, 53~66) years and 87% of those patients were men. The main cause of a bulla was emphysema (80%). Among 30 cases, 16 cases had pneumonia in the lung parenchyma of the peribullous area. Another 7 cases had a regressed bulla accompanied by an air-fluid level within the bulla. The remaining 7 cases showed a spontaneous regression of the bulla without such events. Complete regression of a bulla occurred in 25 cases. A follow-up chest-X ray showed that in all cases except one, the bulla remained in a collapsed state after 24 months. Forced expiratory volume in one second ($FEV_1$) improved in 3 cases and the other 2 cases had increased forced vital capacity (FVC). In addition, total lung capacity (TLC) and residual volume (RV) decreased in another 2 cases. Conclusion: Regression of a lung bulla occurred not only after pneumonia or the presence of air-fluid level within the bulla, but also without such episodes. The clinical course of regression of a lung bulla varied. After regression of a bulla, lung function could be improved in some cases.
The Transactions of The Korean Institute of Electrical Engineers
/
v.61
no.9
/
pp.1350-1357
/
2012
Medical system for personal health management recently changes its paradigm from hospital service to self home care based on ubiquitous technology for healthcare anywhere at any time. The present study developed a wireless bio-signal measurement system for patients to self manage pulmonary disease and benign prostate hyperplasia(BPH), both of which are chronic diseases with increasing frequency in modern society. Velocity-type respiratory air flow transducer adapted to develop respiratory module for pulmonary disease management was simplified in structure to measure uni-directional flow since most important diagnostic parameters are evaluated on the expiratory flow signal only. Standard weight measurement technique was introduced to obtain urinary flow signal for BPH management. Three load cell signals were acquired for averaging to minimize noise, followed by accuracy evaluation. Transmission and receiver modules were also developed with user program for wireless communication. Averaged relative errors were 2.05 and 1.02% for respiratory volume and maximal flow rate, respectively, and the relative error was 2.17% for urinary volume, demonstrating that both modules enabled very accurate measurements. Wireless communication distance was verified within 15m, long enough for home care application. The present system allows the user to select a necessary measurement module on a particular health demand and to immediately provide the self-test results, thus better quality health care would be possible.
Background: Predicting postoperative lung function after pneumonectomy is essential. We retrospectively compared postoperative lung function to predicted postoperative lung function based on computed tomography (CT) volumetry and perfusion scintigraphy in patients who underwent pneumonectomy. Methods: Predicted postoperative lung function was calculated based on perfusion scintigraphy and CT volumetry. The predicted function was compared to the postoperative lung function in terms of forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1), using 4 parameters: FVC, FVC%, FEV1, and FEV1%. Results: The correlations between postoperative function and predicted function based on CT volumetry were r=0.632 (p=0.003) for FVC% and r=0.728 (p<0.001) for FEV1%. The correlations between postoperative function and predicted postoperative function based on perfusion scintigraphy were r=0.654 (p=0.002) for FVC% and r=0.758 (p<0.001) for FEV1%. The preoperative Eastern Cooperative Oncology Group (ECOG) scores were significantly higher in the group in which the gap between postoperative FEV1 and predicted postoperative FEV1 analyzed by CT was smaller than the gap analyzed by perfusion scintigraphy (1.2±0.62 vs. 0.4±0.52, p=0.006). Conclusion: This study affirms that CT volumetry can replace perfusion scintigraphy for preoperative evaluation of patients needing pneumonectomy. In particular, it was found to be a better predictor of postoperative lung function for poor-performance patients (i.e., those with high ECOG scores).
Background: We tried to examine the small airway diseases which can be found early, in workers exposed to inorganic dusts. This is measured in normal breath by using the impulse oscillometry (IOS). Methods: The Pulmonary function test (forced vital capacit [FVC], forced expiratory volume in one second [$FEV_1$], forced expiratory flow between 25% and 75% of vital capacity [$FEF_{25-75}$]), IOS resistance (Rrs at 5, 10, 15, 20, 25, 35 Hz) and reactance (Xrs at 5, 10, 15, 20, 25, 35 Hz) were measured for 454 workers. The subjects were classified into 173 workers of normal (38.1%) and 281 patients with pneumoconiosis (61.9%). Results: There were significant differences between normal and patients with FVC ($3.82{\pm}0.61$ vs. $3.53{\pm}0.56L$), $FEV_1$ ($2.67{\pm}0.63$ vs. $2.35{\pm}0.48L$), and $FEF_{25-75}$ ($1.88{\pm}0.95$ vs. $1.47{\pm}0.80L/sec$) between groups (p<0.05). And as for IOS, there was no significant difference in resistance (Rrs) (p>0.05), and there were significant differences between normal and patients with reactance (Xrs) 15 Hz ($0.003{\pm}0.05$ vs. $-0.006{\pm}0.04kPa/L/s$), 20 Hz ($0.043{\pm}0.05$ vs. $0.031{\pm}0.04kPa/L/s$), and 35 Hz ($0.141{\pm}0.05$ vs. $0.131{\pm}0.05kPa/L/s$) between groups (p<0.05). Conclusion: We could find out that 15 Hz, 20 Hz, and 35 Hz values of reactance were significantly influenced by pneumoconiosis. When usefulness and reproducibility to carry out the IOS are considered, it is thought that in future work will be required to draw the reference values for normal Korean persons.
Background: Airway obstruction and the extent of emphysema are reported to be responsible for reduced bone mineral density (BMD). Corresponding to different phenotypes of a pulmonary disease, different severity in extra pulmonary features may exist. We compared BMDs of subjects with or without airway obstruction and/or emphysema and investigated the relationships among BMD, the severity of airway obstruction, and the extent of emphysema. Methods: Using a university hospital database, we reviewed patients over 40 years old who performed spirometry, computed tomography of chest, and measurement of BMD of the lumbar (L) spine. According to the presence or absence of airway obstruction and/or emphysema, four groups were classified. Results: Among a total of 59 subjects, 33 (56%) had osteoporosis. The prevalence of osteoporosis in subjects with no airway obstruction and no emphysema, those with only emphysema, those with only airway obstruction, and those with both airway obstruction and emphysema were 42%, 57%, 64%, and 73%, respectively (p=0.047 by linear-by-linear association). The mean T-scores of BMD of L1 (p=0.032) and L1-4 spines were different among the four groups (p=0.034). Although the T-score of L1 BMD negatively correlated with the extent of emphysema (r=-0.275, p=0.035) and positively with each of body mass index (BMI) (r=0.520, p<0.001), forced expiratory volume in one second ($FEV_1$) (r=0.330, p=0.011), $FEV_1$/forced vital capacity (r=0.409, p=0.001), and forced expiratory flow at 25~75% of FVC ($FEF_{25-75%}$) (r=0.438, p=0.0001), respectively, multiple linear regression analysis indicated that BMI (p<0.001) and $FEF_{25-75%}$ were predictive of BMD (p=0.012). Conclusion: Low BMI and airway obstruction were strongly associated with reduced bone density rather than the extent of emphysema.
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