• 제목/요약/키워드: Experimental study

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흰쥐에서 아급성 연독성에 대한 감두탕의 예방효과에 관한 연구(II) - 소변 및 혈액에 미치는 영향을 중심으로 - (A Study on the Preventive Effect of Kam Doo Decoction on the Subacute Lead Toxicity in Rats)

  • 이선동;이용욱;방형애
    • 한국환경보건학회지
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    • 제20권1호
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    • pp.83-95
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    • 1994
  • This study was performed to investigate the preventive effect of KDD against lead toxicity. KDD of 133, 266, 532 and 1,064 mg/kg were administered twice to the rats of Sprague-Dawley strain and then 300 mg/kg lead acetate was given to times, respectively. 1. The $\delta$-ALAD concentration in the urine showed 10.6 ~16.4 mg/kg in the control group indicated statistical significance for the experimental group II, III, IV, V (p<0.05). Also, the Coproporphyrin concentration had 0.119 ~ 0.226 $\mu$g/ml in the control group indicated statiscial significance for the experimental group V of 10 weeks (p<0.05). 2. The $\delta$-ALAD concentration in the blood showed 13.28 ~ 16.08 ALAD unit in the control group indicated statistical significance for the experimental group I (Pb 300 mg/kg) of 6 and 8 weeks, for the experimental group III, IV of 8 and 10 weeks, and for the experimental group V of 4 weeks (p<0.05). The $\delta$-ALAD concentration of experimental group I (Pb 300 mg/kg) group was inclined to decrease during the experiment period. The $\delta$-ALAD concentration of experimental group I (Pb 300 mg/kg) showed statistical significance for the experimental group II, III, IV, V of 6, 8 and 10 weeks. But, there was no statistical significance in the concentration change of hemoglobin, RBC, WBC, hematocrit, Ca, protein among the experimental groups. In conclusion, this study revealed the preventive effect of KDD against lead toxicity and its mechnism inferred to facilitate lead excretion in urinary following hinderance of lead absorption in the gastric-intestine and organs.

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안구운동이 성인 편마비 환자의 마비측에 따른 균형증진에 미치는 영향 (The Effect of Eye Movement on Balance Improvement by Plegia Side of Adult Hemiplegic Patient)

  • 구봉오;배성수;김한수;이동호
    • The Journal of Korean Physical Therapy
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    • 제14권4호
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    • pp.1-19
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    • 2002
  • The purpose of this study is to identify influence that eye movement have an effect on postural control and balance performance by plegia side of the impaired patients of central nervous system. Subjects are patients with the impairment of central nervous system and experimental and control groups are forty people and thirty people seperatively, Total subjects were selected to seventy persons, but twelve persons of experimental group quit during the experimental periods and eight persons of control group did not measure after exercise. Therefore, twenty eight persons of experimental group and twenty two persons of control group were selected in this study and experimental group peformed eye movement for eight weeks according to the exercise program of this study. The measurement of dependent variable is right static balance, left static balance, bilateral static balance, and bilateral dynamic balance before exercise and after eighth week of exercise, examiner again measured and analyzed the results. The results were as follows: 1. As the result of comparing balance performance ability after test of the experimental and control group with right hemiplegia and control group, all of static balance performance ability of right side (p < 0.01), static balance performance ability of left side (p < 0.01), static balance performance ability of bilateral side(p < 0.01), dynamic balance performance ability of bilateral side(p < 0.05) of experimental group were statistically greater improved than those of the control group. 2. As the result of comparing balance performance ability after test of the experimental and control group with left hemiplegia and control group, all of static balance performance ability of right side (p < 0.01), static balance performance ability of left side (p < 0.01), static balance performance ability of bilateral side(p < 0.05), dynamic balance performance ability of bilateral side(p < 0.05) of experimental group were statistically greater improved than those of the control group.

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성견 치조골 결손부에 자가골이식과 조직유도재생막을 이용한 치주치료시 치유효과에 관한 비교연구 (COMPARATIVE STUDY OF AUTOGENOUS BONE GRAFT AND GUIDED TISSUE REGENERATION IN THE TREATMENT OF PERIODONTAL DEFECT IN DOGS)

  • 홍기석;김종여;정진형
    • Journal of Periodontal and Implant Science
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    • 제24권1호
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    • pp.205-216
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    • 1994
  • The goal of periodontal therapy is the regeneration of the periodontium lost by periodontal disease. The purpose of this study was to evaluate the regenerative potential of the autogenous bone graft and guided tissue regeneration in the treatment of periodontal bony defect in dogs. Experimental periodontitis were induced in the mandibular left 3rd premolar and right 3rd and 4th premolars of 5 dogs using orthodontic ligature wire. After 6 weeks, the ligature wire removed, surgical procedure were performed as follows. 1) control group : Flap operation(Mn.Lt 3rd premolar) 2) experimental group I : Flap operation + autogenous bone graft (Mn.Rt. 3rd premolar) 3) experimental group II : Flap operation + Gore-Tex membrane (Mn.Rt. 4th premoalr) Thereafter, dogs were sacrificed on the 1,2,4,8,16th week and the specimens were prepared and stained with hematoxyline-eosin stain for the light microscopic examination. The results of this study were as follows. 1. The apical migration of junctional epithelium was most remarkable in the flap operation and the experimental group II was less than the experimental group I. 2. In the formation of new alveolar bone, it was found in experimental group I,II and experimental group I is more than II. In the control group, few bone formation was found. 3. In the formation of new cementum, it was found in experimental group I,II and experimental group II is more than I. So, the periodontal therapy combined with autogenous and guided tissue regeneration will be produce the periodontal regeneration.

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건강증진프로그램이 재가뇌졸중환자의 기능상태에 미치는 효과 (The Effects of the Health Promotion Program on Functional Status of the In-house Stroke Patients)

  • 박혜경
    • 재활간호학회지
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    • 제6권2호
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    • pp.213-225
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    • 2003
  • The purpose of this study is to develop and evaluate the health promotion program to increase the functional status of the in-house stroke patients. The subjects for the experiment are 38 in-house stroke patients in a health center and welfare centers suffering from hemiplegia. The experimental group consists of 19 stroke patients and the control group consists of another 19 stroke patients. The program was applied to the experimental group for 8 weeks. The subjects were given health education at the first week. At the second and the fifth week they were given counselling on health by home visit. At the third, the fourth, the sixth and the seventh week they were interviewed by phone about health, and at the last week they shared their experiences through group meeting. The results of the study are as follows: 1. The degree of ADL in the experimental group increased significantly, compared with that of the control group. 2. In the experimental group the degree of Range of Motion in shoulder abduction, elbow flexion, hip flexion and ankle dorsiflexion increased significantly, compared with that of the control group. 3. In the experimental group the degree of muscle strength in elbow flexion, knee extension, and ankle dorsiflexion increased significantly, compared with that of the control group. 4. Systolic pressure, diastolic pressure in the experimental group decreased significantly, compared with that the control group. 5. HWR in the experimental group didn't decreased significantly, compared with that the control group. 6. The degree of depression in the experimental group decreased significantly, compared with that the control group. 7. The degree of social adaptation in the experimental group increased significantly, compared with that the control group. The results above show that the health promotion program for this study was effective in promoting the performance of lifestyle for health improvement of the in-house stroke patients. Therefore, it is considered that the program can be used as an efficient nursing intervention for the in-house stroke patients who need continuous health-improving behaviors.

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노먼 맥라렌의 실험적 애니메이션과 움직임 표현 연구 (A Study on the Experimental Animation and Movement Expression of Norman McLaren)

  • 홍일양
    • 한국콘텐츠학회논문지
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    • 제19권4호
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    • pp.458-465
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    • 2019
  • 실험애니메이션은 실험정신 그 자체로 독립 예술애니메이션이자 작가주의적 실험정신으로 집약된 영상예술이다. 특히 노먼 맥라렌은 뛰어난 창의력과 감성으로 시각적 표현 기술에 대한 과학적 탐구와 상식을 초월한 실험을 통해 작품마다 독창적인 조형미를 추구하며 오늘날 영상매체의 혁신을 불러온 실험애니메이션의 거장으로써 애니메이션 작품의 미학적 가치는 매우 높다. 그러므로 다양한 기법의 도전으로 실험애니메이션의 영역을 확장하고 각 프레임 사이에서 일어나는 움직임 창조에 관한 끊임없는 탐구를 수행했던 노먼 맥라렌의 실험적 표현 방식을 분석하고 그가 집중한 움직임의 표현을 연구하는 것은 의미가 있다. 그 결과 그의 움직임 표현의 가장 큰 특징은 운동성의 반복과 변형의 반복으로 분석되었으며 이러한 도출이 실험 방식에 대한 단순 의문보다는 보다 구체적인 형태의 탐구가 요구되는 실험 방식의 실험애니메이션으로 이해되길 바란다. 또한 대학교육에서 애니메이션 창작의 가능성과 나아갈 방향을 심층적으로 모색하기 위한 선행 연구로 의미가 있기를 바란다.

내접 유성식 감속기의 소음원 규명에 대한 실험적 연구 (An Experimental Study on the Noise Identification of a Planocentric Gear Reducer)

  • 정진태;홍일화;윤안수
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2007년도 추계학술대회논문집
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    • pp.697-701
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    • 2007
  • In this paper, noise sources of a planocentric gear reducer are identified by experimental mehod. This study consider a reduction method of a noise/vibration about the gear, axle, bearing and others. Namely, the purpose of this study is to reduce a noise/vibration for a stability of the total system. Form the data to be measured through an experimental method, the problems of the gear, axle, bearing and others are examined closely, and the reducer is derived the model to be the engineering. The mechanism of the problem occurrence is examined through a parametric research about an each influence factor(Load). Lastly, the results of this study propose the model to be improved.

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밸런스 테이핑 요법이 노인의 다리통증에 미치는 효과 (Effects of Balance Taping Therapy for Elders with Leg Pain)

  • 박경숙;박가윤;류언나
    • 기본간호학회지
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    • 제15권1호
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    • pp.45-52
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    • 2008
  • Purpose: The purpose of this study was to examine the effects of balance taping for elders suffering from leg pain. Method: This study was a nonequivalent pretest-posttest design, quasi-experimental study. There were 25 elders in the experimental group and 25 in the control group. The degree of leg pain was measured three times. Results: In the experimental group, the leg pain score before taping was 6.28, but 1 hour after the taping was applied it was 3.24, and at 24 hours after the taping was applied, 2.16. The leg pain score for elders in the experimental group decreased significantly but for those in the control group, it hardly changed. Conclusion: The findings of this study support the conclusion that balance taping may benefit individuals with leg pain. Also, balance taping therapy can be used as an independent nursing intervention.

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An experimental study and new correlations of viscosity of ethylene glycol-water based nanofluid at various temperatures and different solid concentrations

  • Bidgoli, Mahmood Rabani;Kolahchi, Reza;Karimi, Mohammad Saeed
    • Structural Engineering and Mechanics
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    • 제58권1호
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    • pp.93-102
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    • 2016
  • This article presents an experimental study on the effect of temperature and solid volume fraction of nanoparticles on the dynamic viscosity for the CuO/EG-water nanofluid. Nanoparticles with diameter of 40 nm are used in the present study to prepare nanofluid by two-step method. A "Brookfield viscometer" has been used to measure the dynamic viscosity of nanofluid with solid volume fraction up to 2% at the temperature range between 20 to $60^{\circ}C$. The findings have shown that dynamic viscosity of nanofluid increases with increasing particle volume fraction and decreasing temperature. Nine different correlations are developed on experimental data point to predict the relative dynamic viscosity of nanofluid at different temperatures. To make sure of accuracy of the proposed correlations, margin of deviation is presented at the end of this study. The results show excellent agreement between experimental data and those obtained through the correlations.

초등학생의 실험기구 교육을 위한 TEP 활동의 개발 및 적용 (Development and Application TEP Activity for the Education of Experimental Apparatus at Elementary School)

  • 전소연;박종석
    • 대한화학회지
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    • 제64권6호
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    • pp.379-388
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    • 2020
  • 본 연구에서는 초등학생의 실험기구 교육을 위한 TEP 활동(Trigger interest; 흥미 유발-Explore experimental apparatus; 실험기구 탐색-Practice experimental apparatus; 실천적 사용)을 개발하고 이를 적용하여 그 효과를 알아보았다. 과학을 처음 접하는 초등학교 3학년을 대상으로 교과서에 제시되어있는 실험기구 중 4가지(비커, 전자저울, 유리막대, 약숟가락)를 선별하여 연구를 진행하였다. 그 결과 TEP 활동을 통해 단편적인 사용법이나 주의사항만을 알고 있던 학생들이 실험기구의 생김새에 따른 특징과 연관 지어 실험기구에 대한 설명을 할 수 있게 되었다. 또한 실제로 사용해보는 활동을 통해 실험기구 사용 능력이 향상되었다. 평소 과학 수업에서의 모습을 관찰한 결과 실험기구에 대해 학습한 내용을 떠올리며 적절하게 사용하려는 학생들이 많아졌으며 반복적인 활동을 통해 그 수가 증가함을 알 수 있었다. 초등학교에서 처음 배우게 되는 실험기구에 대한 지식적 이해와 사용 능력은 초, 중, 고등학교를 지나 실험이 주로 이루어지게 되는 대학교까지 영향을 미친다. 잘못된 용도와 사용법으로 실험을 하게 된다면 실험 결과의 신뢰도가 떨어질 뿐만 아니라 안전사고의 확률 또한 높아진다. 이러한 관점에서 본 연구를 통해 실험기구에 대한 교육을 초등 과학 교육과정에서 더욱 중요하게 다루어져야 하며 실제 교육을 해야 하는 교사들을 위해 다양한 교육 자료나 교수법이 개발되어야 함을 확인할 수 있었다.

경피적 전기신경자극이 폐암 환자의 폐엽절제술 후 통증과 폐기능에 미치는 효과 (The Effect of Transcutaneous Electrical Nerve Stimulation on Pain and Pulmonary Function with Post-lobectomy Patient with Lung Cancer)

  • 전현례;박정숙
    • 성인간호학회지
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    • 제21권5호
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    • pp.519-528
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    • 2009
  • Purpose: This study was designed to evaluate the effect of TENS on pain and pulmonary function of post-lobectomy patients with lung cancer. Methods: The study data collection was done from February 4, 2008 to February 7, 2009. The subjects were assigned at random to the experimental group and control group with 20 subjects in each group. The experimental group was measured for pain and pulmonary function after surgery and then again after applying TENS 100 Hz frequency and 40 mA output for 20 minutes. The control group was measured the same as the experimental group except applying sham TENS. Results: The pain score of the experimental group which had TENS applied revealed that there were more significant reductions than the control group which had sham TENS applied. There was no significant difference with the number of times of receiving analgesics between the experimental and control group. The effect of TENS on pulmonary function was significantly different between the experimental group and the control group on VC 2 hours after surgery. There was no significant difference between FVC and FEV1. Conclusion: The findings of the study indicate that the TENS is effective in easing the pain of patients after a lobectomy.

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