• Title/Summary/Keyword: Experimental formula

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Effects of Soy-Based Infant Formula on the Fatty Acid Composition of Erythrocytes and Plasma Lipid Levels in Full-Term Infants (액상 대두유 섭취가 영아의 적혈구 지방산 조성과 혈청 지질농도에 미치는 영향)

  • 조여원;장영은;신경욱;김정숙;김승보;최영미
    • Journal of Nutrition and Health
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    • v.34 no.7
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    • pp.778-785
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    • 2001
  • In Korea, the concerns about the consumption of soy-based infant formulas have received considerable public attention. In has been known that the n-3/n-6 ratio of soy has a beneficial effect on the health. This study was conducted to investigate whether the soy-based infant formula has an effect on the composition of fatty acids in erythrocytes with regard to the plasma lipid levels in full-term infants. The infants who were delivered at Kyung Hee Medical Center were recruited. Experimental groups were the breast milk group(n=17), soy-based infant formula group(n=12) and casein-based infant formula group(n=19). Anthrophometic and dietary assessments were performed and the composition of RBC fatty acids and blood lipid levels were measured. The body weight, length, chest circumference and head circumference of the subjects were normal growth range showing no significant difference among the experimental groups. The ratio of n-3/n-6 ratio in breast milk, soy-based infant formula and casein-based infant formula were 0.11, 0.14 and 0.13, respectively. N-3/n-6 ratio of the subjects erythrocyte fatty acids for each groups were 0.18, 0.21 and 0.17, respectively. Most of the fatty acids of erythrocyte were not significantly different among the three experimental groups. The blood lipid levels of each experimental group were normal range. The total lipid level of casein-based formula group was higher than that of other experimental groups and LDL-cholesterol level of soy-based formula group was the lowest among the three groups.

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The Effects of Soy-Based Infant Formula on Growth and Development, and the Isoflavone Concentration of Plasma and Urine in Full-Term Infants (액상대두유 섭취가 영아의 성장.발달과 혈액 및 뇨 중 Isoflavone 농도에 미치는 영향)

  • 이현주;이혜옥;장영은;김정숙;정사준;조여원
    • Journal of Nutrition and Health
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    • v.36 no.8
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    • pp.841-850
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    • 2003
  • Soy-based formula has been used for centuries in Korea. Soybeans contain phytochemicals with a biochemically active component, isoflavone. Isoflavone is a kind of phytoestrogens, structurally and functionally similar to estrogen. This study was conducted to investigate the effects of soy-based infant formula on growth, development, and isoflavone concentration in the plasma and urine. Thirty-nine healthy infants who were delivered at K university medical center were recruited. Experimental groups were the breast milk group (n = 15, BM) who were fed breast milk, soy-based formula group (n = 10, SBF) who were fed soy-based infant formula, and the casein-based formula group (n = 14, CBF) who were fed casein-based infant formula for 4 months. HPLC analysis was used to measure the concentration of isoflavones. The measurements of infant weight, length, head circumference and chest circumference were all in the normal growth range and were similar among the experimental groups. No significant differences were found in the scores of total mean of infant development test (Development Quotient, DQ) among the experimental groups. The isoflavone content of soy-based formula was significantly higher than. that of breast milk and casein-based formula. Plasma concentration of daidzein and genistein in the infants fed soy-based formula (daidzein : 264.1 ng/ml, genistein : 392.1 ng/ml) was significantly higher (p<.0001) than that in infants fed breast milk (daidzein : 3.4 ng/ml, genistein : 3.8 ng/ml) and casein-based formula (daidzein: 8.1 ng/ml, genistein: 9.3 ng/ml). Also, urinary daidzein and genistein concentrations in infants fed soy-based formula (daidzein: 19.82 $\mu$g/ml, genistein : 17.89 $\mu$g/ml) were significantly higher (p<.001) than those in infants fed breast milk (daidzein: 0.28 $\mu$g/ml, genistein : 0.22 $\mu$g/ml) and casein-based formula (daidzein : 0.45 $\mu$g/ml, genistein : 0.33 $\mu$g/ml).

Correction and Experimental Verification of Velocity Circulation in a Double-blade Pump Impeller Outlet

  • Kai, Wang;Qiong, Liu
    • International Journal of Fluid Machinery and Systems
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    • v.8 no.4
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    • pp.311-317
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    • 2015
  • It is difficulty to calculate velocity circulation in centrifugal pump impeller outlet accurately. Velocity circulations of a double-blade pump impeller outlet were calculated with Stodola formula, Weisner formula and Stechkin formula. Simultaneously, the internal flow of impeller for the double-blade pump were measured with PIV technology and average velocity circulations at the 0.8, 1.0 and 1.2 times of design flow were obtained. All the experimental values were compared with the above calculation values at the three conditions. The results show that calculation values of velocity circulations with Weisner formula is close to the experimental values. On the basis of the above, velocity circulations of impeller outlet were corrected. The results of experimental verification show that the corrected calculation errors, whose maximum error is 3.65%, are greatly reduced than the uncorrected calculation errors. The research results could provide good references for establishment of theoretical head and multi-condition hydraulic optimization of double-blade pumps.

Application of Experimental Design to Optimize Vitamin C-90 Tabletting Performance

  • Chang, Kuei-Tu
    • Journal of Pharmaceutical Investigation
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    • v.24 no.3
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    • pp.67-77
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    • 1994
  • The RMS statistical approach has demonstrated its potential in developing pharmaceutical dosage forms and in improving tabletting performance. Using an optimized formula, the tabletting performances of vitamin C-90 such as compressibility, disintegration time, lubrication and friability are significantly enhanced when compared with the performance of a traditional test formula. More important, this method also enables us to serve our customers better. Any customized modification of a suggested formula or any technical problem related performance etc. can be readily resolved by simple examination of the models.

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Dynamic Modeling and Analysis of a Friction Damper in Drum-type Washing Machine with a Magic Formula Model (Magic Formula 모델을 이용한 드럼세탁기용 마찰댐퍼의 동역학적 모델링과 해석)

  • Park, Jin-Hong;Lee, Jeong-Han;Yoo, Wan-Suk;Nho, Gyung-Hun;Chung, Bo-Sun
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.19 no.10
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    • pp.1034-1042
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    • 2009
  • In this paper, the magic formula model was applied for a friction damper in a drum-type washing machine. To describe characteristics of the hysteretic damping force, Physical tests were first carried out to get experimental results using an MTS machine. Then, parameters for the magic formula model were determined from the experimental curves. The ADAMS and MATLAB programs were used for the multibody modeling of the damper and process for parameter identification. The model of drum-type washing machine was applied for a dynamic model of friction damper, in which the accuracy of the proposed damper model was verified.

Experimental Study for Wave Transmission Coefficients of Submerged Structure : I. Permeable Type Structure (수중구조물의 파고전달계수 산정 실험 : I. 투과형 수중구조물)

  • Lee, Jong-In;Bae, Il Rho
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.40 no.5
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    • pp.485-496
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    • 2020
  • Submerged structures such as low-crested breakwaters and artificial reefs have been commonly used for coastal protection. In this study, two-dimensional laboratory experiments were conducted in a wave flume to investigate the wave transmission phenomena of permeable type submerged structures armored by Tetrapods. Different cases of the experimental conditions were included by relative crest depth, relative freeboard, relative crest width, wave steepness and so on. An empirical formula from the experimental data was proposed to predict the wave transmission coefficients over various specifications and structural designs of the permeable type submerged structure. The proposed formula successfully predicted the wave transmission coefficients. In this study, the proposed empirical formula of the wave transmission over the submerged structure was improved from the existing formula.

Experimental Study on Wave Transmission Coefficients of Submerged Structure : II. Rubble-Mound Type Structure armored by Tetrapods (수중구조물의 파고전달계수 산정 실험 : II. 테트라포드 피복 경사형 수중구조물)

  • Lee, Jong-In;Kim, Young Il
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.40 no.5
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    • pp.497-507
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    • 2020
  • Two-dimensional laboratory experiments were conducted in a wave flume to investigate the wave transmission phenomena of rubble-mound type submerged structures armored with Tetrapods. Different experimental conditions were included by considering relative crest depth, relative freeboard, relative crest width, wave steepness, and so on. An empirical formula was proposed to predict the wave transmission coefficients over various specifications and structural designs of the partial perforated (rubble-mound) type submerged structure from the experimental results. The proposed formula successfully predicted the wave transmission coefficients. In this study, the proposed empirical formula of the wave transmission over the rubble-mound type submerged structure was improved from the existing formula.

Experimental Study on Wave Transmission Coefficients of Submerged Structures: III. Impermeable-Type Structure (수중구조물의 파고전달계수 산정 실험 : III. 불투과형 수중구조물)

  • Lee, Jong-In;Cho, Ji Hoon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.40 no.6
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    • pp.593-601
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    • 2020
  • Two-dimensional laboratory experiments were conducted in a wave flume to investigate the wave transmission phenomena of impermeable-type submerged structures armored by concrete blocks. Different experimental conditions were included by considering relative crest depth, relative freeboard, relative crest width, wave steepness, and so on. An empirical formula was proposed to predict the wave transmission coefficients over various specifications and structural designs of the impermeable submerged structure from the experimental results. The proposed formula successfully predicted the wave transmission coefficients. Therefore, in this study, the proposed empirical formula of the wave transmission over an impermeable submerged structure was improved from the existing formula.

Analysis of Drift Prediction Formula Used in the Search and Rescue Mission (수색구조 작업에 사용되는 표류지점 추정 공식 분석)

  • 강신영
    • Journal of Korean Port Research
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    • v.12 no.2
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    • pp.373-384
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    • 1998
  • In search and rescue mission the leeway formula based on the field experiments are utilized for the estimation of wind effect on distressed targets. This paper summarized the leeway formula from the available references. In the summary the environmental data collection method and experimental conditions are described along with the formula. Also the formula currently used in CASP of the U.S. Coast Gurard and CANSARP of the Canadian Coast Guard are discussed.

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Effect of Pork Meat Oligopeptides as a Foodstuff for Experimental Hepatitic Rats (돈육 Oligopeptide를 이용한 간질환식의 효과)

  • Kim, Jong-Hee;Hong, Soon-Kwang
    • The Korean Journal of Food And Nutrition
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    • v.22 no.3
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    • pp.416-420
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    • 2009
  • A formula diet based on pork meat oligopeptides(pork meat protein hydrolysates) was designed for experimental hepatitic rats. The rats were given D-galactosamine for 6 days. During this period, the rats were provided with a 12% casein diet or the formula diet which was low in aromatic amino acids and rich in branched chain amino acids. The formula diet was prepared using pork meat oligopeptides as the principal nitrogen source. The hepatitic rats given the formula diet had lower plasma GOT and GPT concentrations. Additionally, the fischer ratio of the plasma was significantly lower in those rats. However, there was no significant difference in the plasma insulin-like growth factor-I concentration before and after acid-ethanol extraction among groups. These results suggest that the formula diet was better for the animals than the casein diet. Furthermore, these findings suggest that pork meat oligopeptides are an excellent material for preparation of formula diets for patients suffering from hepatitis.