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Effect of Pork Meat Oligopeptides as a Foodstuff for Experimental Hepatitic Rats  

Kim, Jong-Hee (Dept. of Food and Nutrition, Seoil University)
Hong, Soon-Kwang (Dept. of Biological Science, Myoung-Ji University)
Publication Information
The Korean Journal of Food And Nutrition / v.22, no.3, 2009 , pp. 416-420 More about this Journal
Abstract
A formula diet based on pork meat oligopeptides(pork meat protein hydrolysates) was designed for experimental hepatitic rats. The rats were given D-galactosamine for 6 days. During this period, the rats were provided with a 12% casein diet or the formula diet which was low in aromatic amino acids and rich in branched chain amino acids. The formula diet was prepared using pork meat oligopeptides as the principal nitrogen source. The hepatitic rats given the formula diet had lower plasma GOT and GPT concentrations. Additionally, the fischer ratio of the plasma was significantly lower in those rats. However, there was no significant difference in the plasma insulin-like growth factor-I concentration before and after acid-ethanol extraction among groups. These results suggest that the formula diet was better for the animals than the casein diet. Furthermore, these findings suggest that pork meat oligopeptides are an excellent material for preparation of formula diets for patients suffering from hepatitis.
Keywords
oligopeptides; hepatitis rats; D-galactosamine; nitrogen source; fischer ratio, insulin-like growth factor-I;
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Times Cited By KSCI : 3  (Citation Analysis)
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1 Faure M, Moennoz F, Montigon C, Mettraux D, Breuille D, Ballevre O. 2005. Dietary threonine restriction specifiaclly reduces intestinal mucin synthesis in rats. J Nutr 135:486-491   ScienceOn
2 Kim JH, Hong SK. 2009. Preparation and chemical characteristics of food protein hydrolysates. J East Asian Soc Dietary Life 19:45-51   과학기술학회마을   ScienceOn
3 Kim JH, Son MH, Cho JS. 2007. Purified protein and oligopeptide mixture preparation from pork meat and evaluation of their nutritive value: True digestibility, biological value, and net protein utilization. Korean J Food Cookery Sci 23:644-649   과학기술학회마을   ScienceOn
4 Noguchi T, Takahashi S, Kajikawa M, Umezawa T, Takahashi SI, Kato H, Miura Y, Nam TJ, Naito H. 1990. Effect of dietary proteins on the plasma immunoreactive insulin-like growth factor-1/somatomeidin C concentration in the rat. Br J Nutr 63:521-534   DOI   ScienceOn
5 Yamaguchi M, Kandatsu M. 1973. Catabolic rate of body protein in adult rat over an entric period of protein depletion. Agri Biol Chem 37:579-586   DOI
6 Kim JH, Noguchi T. 1992. Studies in the nutritive value of an enzyme hydrolysate of purified meat protein. Report ITO FOU. 10:297-302
7 Kim JH. 1992. Studies on the nutritional significance of enzymatic food protein hydrolysates. Doctorate thesis. Tokyo University of Japan. pp.2-65
8 Adibi SA, Morse EL. 1971. Intestinal transporter of dipeptides in man: Relative importance of hydrolysis and intact absorption. J Clin Invest 50:2226-2275   DOI   PUBMED
9 Habold C, Foltzer-Jourdainne Y, Maho L, Lignot JH. 2005. Intestinal gluconeogenesis and glucose transport according to body fuel availability in rats. J Physiol 566:575-586   DOI   ScienceOn
10 National Research Council. 1978. Nutrient Requirements of Laboratory Animals. pp.3-23. National Academy of Sciences. Washington DC
11 Jurge MD, Aberle ED, Forrest JC, Hedrick HB, Merkel RA. 1975. Principle of Meat Science, 2nd ed pp.128-190. Kendall Hunt Publishing Co
12 Hiroyuki F, Tomohide Y, Kazunori O. 2001. Effect of an aceinhibitory agent, katsuobushi oligopeptide in the spontaneously hypertensive rat and in borderline and mildly hypertensive subjects. Nutr Res 21:1149   DOI   ScienceOn
13 Harper AE. 1976. In Proteins in Human Nutrition. pp.349-352. London and New York Academic Press. Washington DC
14 Hiroyuki F, Keiichi Y, Masaki Y. 2000. Classification and antihypertensive activity of angiotensin 1-converting enzyme inhibitory peptides derived from food proteins. J Food Sci 65:564   DOI   ScienceOn
15 Yoon JA, Son YS. 2009 Effects of Opuntia ficus-indica complexes B(OCB) on blood glucose and lipid metabolism in streptozotocin-induced diabetic rats. Korean J Food Nutr 22:48-56   과학기술학회마을   ScienceOn
16 桐山修八, 荒井綜一. 1990. Nutrition of Peptide. pp.27-179. 北海道大學圖書刊行會. Japan