• 제목/요약/키워드: Experimental formula

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ICR 마우스를 이용한 마황윤폐탕(麻黃潤肺湯)의 진해, 거담, 및 항염 효과 평가 (Antitussive, Expectorant, and Anti-inflammatory Effects of Mahwangyounpae-tang, a Polyherbal Formula in ICR Mice)

  • 정영은;김종대
    • 대한한방내과학회지
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    • 제43권4호
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    • pp.503-513
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    • 2022
  • Objectives: The antitussive, expectorant, and anti-inflammatory effects of Mahwangyounpae-tang (MHYPT) aqueous extracts were observed in appropriate animal models of various respiratory disorders. Methods: MHYPT aqueous extracts were orally administered once a day for 11 days at dose levels of 400, 200, and 100 mg/kg. The effect of MHYPT was determined by comparing its antitussive effect with theobromine (TB), its expectorant effect with ambroxol (AM), and its anti-inflammatory effect with dexamethasone (DEXA). Results: MHYPT aqueous extracts (400 mg/kg) showed favorable antitussive effects comparable to those of TB (50 mg/kg) in the NH4OH-exposure coughing mouse model and expectorant effects comparable to those of AM (250 mg/kg) in the phenol red-secretion mouse model, but MHYPT (400 mg/kg) showed less anti-inflammatory activity compared to DEXA (1 mg/kg) in the xylene-induced acute inflammatory mouse ear model under the experimental conditions used. Conclusion: MHYPT aqueous extracts administered at dosage levels of 400, 200, and 100 mg/kg induced dose-dependent and favorable antitussive, expectorant, and anti-inflammatory activities that occurred by simultaneous modulation of the activity of mast cells and respiratory mucous production under the experimental conditions used in this study.

Studies on CFST column to steel beam joints using endplates and long bolts under central column removal

  • Gao, Shan;Yang, Bo;Guo, Lanhui;Xu, Man;Fu, Feng
    • Steel and Composite Structures
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    • 제42권2호
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    • pp.161-172
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    • 2022
  • In this paper, four specimens of CFST column joints with endplates and long bolts are tested in the scenario of progressive collapse. Flush endplate and extended endplate are both adopted in this study. The experimental results show that increasing the thickness of the endplate could improve the behavior of the joint, but delay the mobilization of catenary action. The thickness of the endplate should not be relatively thick in comparison to the diameter of the bolts, otherwise catenary action would not be mobilized or work effectively. Effective bending deformation of the endplate could help the formation and development of catenary action in the joints. The performance of flexural action in the joint would affect the formation of catenary action in the joint. Extra middle-row bolts set at the endplates and structural components set below the bottom beam flange should be used to enhance the robustness of joints. A special weld access hole between beam and endplate should be adopted to mitigate the chain damage potential of welds. It is suggested that the structural components of joints should be independent of each other to enhance the robustness of joints. Based on the component method, a formula calculating the stiffness coefficient of preloaded long bolts was proposed whose results matched well with the experimental results.

Experimental and numerical study on pre-cambered deep deck-plate system

  • Seung-Ho, Choi;Inwook, Heo;Khaliunaa, Darkhanbat;Sung-Mo, Choi;Kang Su, Kim
    • Computers and Concrete
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    • 제30권6호
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    • pp.445-453
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    • 2022
  • A pre-cambered deep deck-plate system has been developed that can realize a long span by offsetting the deflection caused by a construction load. In this study, finite element (FE) analysis is performed to examine the preload-camber relationship introduced into a deck and calculate the deflection reflecting the ponding effect that arises during concrete pouring. The FE analysis results showed that the stress of the bottom plate was half of the yield stress when the pre-camber of approximately 30 mm was introduced. Based on the FE results, a full-scale deep deck-plate is fabricated, a pre-camber is introduced, and concrete is poured to measure deflection. A deflection calculation formula that reflects the ponding effect is proposed, and the deflections yielded by the proposed model, experimental results, and FE results are compared. Results show that the proposed model can accurately estimate the deflection of non-supported deep deck-plate systems after concrete is poured.

Study on (n, α) reactions for the production of 51Cr, 89Sr, 99Tc, 131I, 133Xe, 137Cs and 153Sm radioisotopes used in nuclear medicine

  • Hallo M. Abdullah;Ali H. Ahmed
    • Nuclear Engineering and Technology
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    • 제55권9호
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    • pp.3352-3358
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    • 2023
  • Nuclear medicine seems to be a decent choice of medicine in the recent decade. The radioactive isotopes 51Cr, 89Sr, 99Tc, 131I, 133Xe, 137Cs and 153Sm are extremely essential in nuclear medicine. The excitation functions of the 54Fe (n, α) 51Cr, 92Zr (n, α) 89Sr, 102Rh (n, α) 99Tc, 134Cs (n, α) 131I, 136Ba (n, α) 133Xe, 140La (n, α) 137Cs and 156Gd (n, α) 153Sm reactions were calculated in this study using the EMPIRE 3.2.3 and TALYS 1.95 nuclear codes. Additionally, the cross sections at 14-15 MeV were calculated using empirical formulae and the experimental data. The computer codes were compared to the experimental data and Empirical formulas as well as the evaluated data (TENDL 2021, JENDL 3.3, JENDL 5, JEFF 3.3, EAF 2010, CENDL 3.1, CENDL 3.2, ROSFOND 2010, FENDL 3.2 b, and BROND 3.1).

Computation of the Current Limiting Behavior of BSCCO-2212 High-Temperature Superconducting Tube with Shunt Coils

  • Kim, H.M.;Park, K.B.;Lee, B.W.;Oh, I.;Sim, J.;Hyun, O.B.
    • 한국초전도ㆍ저온공학회논문지
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    • 제8권4호
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    • pp.22-25
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    • 2006
  • This paper deals with the computation of the current limiting behavior of high-temperature superconducting (HTS) modules for the superconducting fault current limiter (SFCL). The SFCL module consists of a monofilar type BSCCO-2212 tube and a shunt coil made of copper or brass. The shunt coil is connected to the monofilar superconducting tube in parallel. Through analysis of the quench behavior of the monofilar component with shunt coils, it is achieved to drive an equivalent circuit equation from the experimental circuit structure. In order to analyze the quench behavior of the SFCL module, we derived a partial differential equation technique. Inductance of the monofilar component and the impedance of the shunt coil are calculated by Bio-Savart and Ohm's formula, respectively. We computed the quench behavior using the calculated values, and compared the results with experimental results for the quench characteristics of a component. The results of computation and test agreed well each other, and it was concluded that the analytic result could be applied effectively to design of the distribution-level SFCL system.

Experimental study on bearing capacity of PFCC column-RC beam joint reinforced with CST

  • Ping Wu;Dongang Li;Feng Yu;Yuan Fang;Guosheng Xiang;Zilong Li
    • Steel and Composite Structures
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    • 제47권1호
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    • pp.19-36
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    • 2023
  • An experimental study of eleven PVC-FRP Confined Concrete (PFCC) column-Reinforced Concrete (RC) beam joints reinforced with Core Steel Tube (CST) under axial compression is carried out. All specimens are designed in accordance with the principle of "weak column and strong joint". The influences of FRP strips spacing, length and steel ratio of CST, height and stirrup ratio of joint on mechanical behavior are investigated. As the design anticipated, all specimens are destroyed by column failure. The failure mode of PFCC column-RC beam joint reinforced with CST is the yielding of longitudinal steel bars, CST and stirrups of column as well as the fracture of FRP strips and PVC tube. The ultimate bearing capacity decreases as FRP strips spacing or joint height increases. The effects of other three studied parameters on ultimate bearing capacity are not obvious. The strain development rules of longitudinal steel bars, PVC tube, FRP strips, column stirrups and CST are revealed. The effects of various studied parameters on stiffness are also examined. Additionally, an influence coefficient of joint height is introduced based on the regression analysis of test data, a theoretical formula for predicting bearing capacity is proposed and it agrees well with test data.

Axial compressed UHPC plate-concrete filled steel tubular composite short columns, Part I: Bearing capacity

  • Jiangang Wei;Zhitao Xie;Wei Zhang;Yan Yang;Xia Luo;Baochun Chen
    • Steel and Composite Structures
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    • 제47권3호
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    • pp.405-421
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    • 2023
  • An experimental study on six axially-loaded composite short columns with different thicknesses of steel tube and that of the concrete plate was carried out. Compared to the mechanical behavior of component specimens under axially compressed, the failure modes, compression deformation, and strain process were obtained. The two main parameters that have a significant enhancement to cross-sectional strength were also analyzed. The failure of an axially loaded UHPC-CFST short column is due to the crushing of the UHPC plate, while the CFST member does reach its maximum resistance. A reduction coefficient K'c, related to the confinement coefficient, is introduced to account for the contribution of CFST members to the ultimate load-carrying capacity of the UHPC-CFST composite short columns. Based on the regression analysis of the relationship between the confinement index ξ and the value of fcc/fc, a unified formula for estimating the axial compressive strength of CFST short columns was proposed, combined with the experimental results in this research, and an equation for reliably predicting the strength of UHPC-CFST composite short columns under axial compression were also proposed.

Research on prediction and analysis of supercritical water heat transfer coefficient based on support vector machine

  • Ma Dongliang;Li Yi;Zhou Tao;Huang Yanping
    • Nuclear Engineering and Technology
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    • 제55권11호
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    • pp.4102-4111
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    • 2023
  • In order to better perform thermal hydraulic calculation and analysis of supercritical water reactor, based on the experimental data of supercritical water, the model training and predictive analysis of the heat transfer coefficient of supercritical water were carried out by using the support vector machine (SVM) algorithm. The changes in the prediction accuracy of the supercritical water heat transfer coefficient are analyzed by the changes of the regularization penalty parameter C, the slack variable epsilon and the Gaussian kernel function parameter gamma. The predicted value of the SVM model obtained after parameter optimization and the actual experimental test data are analyzed for data verification. The research results show that: the normalization of the data has a great influence on the prediction results. The slack variable has a relatively small influence on the accuracy change range of the predicted heat transfer coefficient. The change of gamma has the greatest impact on the accuracy of the heat transfer coefficient. Compared with the calculation results of traditional empirical formula methods, the trained algorithm model using SVM has smaller average error and standard deviations. Using the SVM trained algorithm model, the heat transfer coefficient of supercritical water can be effectively predicted and analyzed.

실험적 응력해석의 IITC 방식에 의한 콘크리트 구조물 잔류응력 평가 (Evaluation of Residual Stress using IITC of Experimental Stress Analysis on Concrete Structure)

  • 이호범;한상희;장일영
    • 대한토목학회논문집
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    • 제34권2호
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    • pp.415-424
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    • 2014
  • 기존 콘크리트 구조물 내력은 변위 및 스트레인 게이지를 통해 기지의 가력에 따른 변화량을 계측하고, 그 결과를 수치해석 결과와 비교하여 평가한다. 이는 결과적으로 현존 콘크리트의 잔류응력을 계측 평가하므로써 완성될 수 있다. 본 논문은 실험적 응력해석법의 일환으로 콘크리트 구조물에 대한 잔류응력을 비파괴적인 방식으로 평가하는 IITC (Instrumented Indentation Technique for Concrete) 시스템 개발과 관련된 것으로 콘크리트 구조물 표면에서 압입하중과 압입깊이와의 상관관계를 이용한 실험적 평가방법을 논하였다. 본 연구에서는 구성되는 H/W 및 분석용 S/W는 새롭게 개발하였으며, 다각도의 실험결과를 이용하여 콘크리트 구조물에서의 실험적 잔류응력 추정식을 창출하였고, 자동으로 잔류응력을 평가케 함으로써 콘크리트 구조물의 축성단계에서부터 유지관리 단계에까지 자유롭게 내력을 산정할 수 있도록 하였다.

식이중 단백질과 지방수준이 흰쥐의 성장, 질소와 에너지 이용 및 체조성에 미치는 영향 (Effect of Dietary Protein and Fat Levels on the Utilization of Nitrogen and Energy and Body Composition in Rats)

  • 권순형
    • Journal of Nutrition and Health
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    • 제20권2호
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    • pp.122-134
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    • 1987
  • In order to investigate the effect of dietary protein and fat levels on the growth and the utilization of nitrogen and energy and body composition in rats, Sprague\ulcornerDawley 48 male rats of 8 weeks old weighing approxijIlately 215-220g were subjected to feeding trials for 8 weeks and then subsequently to metabolic trials for 2 weeks. Four dietary protein levels (4, 8, 16, 32%) and each protein level contained two fat levels(3.9, 11.7%=1O,3J% of 3600kcal ME/kg) by addition of an appropriate amount of carbo\ulcornerhydrate and the following results were obtained. The body weight gain and food efficiency ratio of the rats to which a diet of 16% protein and 3.9% fat was fed were significantly higher than in either case of 8% pro\ulcornertein diet or of 32% protein diet. The digestibility of protein in the experimental diets was 73.3 -93.4%. The digesti\ulcornerbility of energy ( energy absorption) in the experimental diets was 83.2 -91.5%. The utilization of protein and the metabolic energy efficiency in the experimental diets was highest at the diet of 8% protein and 3.9% fat. The analysis of the body composition after feeding trials for 8 weeks has shown that the content of body water and protein were not affected by protein and fat levels in diet. The content of body fat in the rats to which 3.9% fat diet was fed was high\ulcornerer than that in those to which 11.7% fat diet was fed. From the above experimental results it may be suggested that the best formula of diet for the 8 weeks old rats may be composed of the 8% protein and 3.9% fat.

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