• Title/Summary/Keyword: Experimental formula

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A Study on the Relationship between School-age Obesity and Type of Feeding in Infant Period (영아시기 수유 방식과 초기 학동기 비만과의 관련성에 관한 연구)

  • Cho, Kyung Lae;Kim, Soo Young
    • Clinical and Experimental Pediatrics
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    • v.48 no.11
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    • pp.1166-1171
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    • 2005
  • Purpose : The aim of this study was to evaluate whether breast milk feeding at infancy has the effect of a programming agent preventing school-age obesity, or whether formula milk feeding is the cause of elementary school-age obesity. Methods : We randomly selected 4 elementary school in Masan and Changwon city. We calculated the BMI and obesity degree from height and weight data on the school record of 1,275 children of first and second grade. The parents of 1,275 children were asked to a questionnaire about their birth history and feeding modality during infancy. Based on these data, we categorized them into 4- different groups : breast fed for less than 2 months; breast fed for 2-6 months; breast fed more than 6 months; mixed fed. We compared the mean BMI, obesity degree and prevalence rates of obesity of each groups. Results : There was no statistical difference on the prevalence rates of overweight and obesity, which was defined by BMI, according to the duration of breast feeding. The same was true for mild obesity and moderate obesity, which was defined by obesity degree. The mean BMIs and the mean obesity degree were not different among different feeding types. Conclusion : There seems to be no protective effect of breast feeding during infancy on reducing the prevalence rates of overweight and obesity. However, even wider and larger studies considering confounding factor might be needed to reach a definite conclusion in the future.

Current Understanding and Practices of Breast feeding by Mothers (모유수유에 대한 산모의 의식과 실천 현황)

  • Park, Eun Young;Cho, Su Jin;Lee, Keun
    • Clinical and Experimental Pediatrics
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    • v.48 no.11
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    • pp.1162-1165
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    • 2005
  • Purpose : The objective of this survey was to develop an operational plan for breast feeding education. In order to comprehend current breast feeding patterns, we aimed to examine the knowledge, attitude and practices regarding breast feeding of mothers and to compare the data with a similar study done 6 years ago. Methods : A total of 127 mothers who delivered healthy babies at Ewha Womans University Dongdaemun Hospital were interviewed and asked to complete a survey on their perception of breast feeding during their postpartum stay in the hospital. A follow up phone interview was carried out at 1, 2 and 3 months after delivery and similar questions were asked. Results : At the time of delivery, 96.1 percent of mothers planned to breast feed, including 73.2 percent of exclusive breast feeding and 22.8 percent of mixed feeding. The duration of breast feeding planned was mostly 7-12 months. Breast feeding had been recommended by family members. Between 1-3 months, exclusive breast feeding was maintained at least 50 percent but a large number of mothers who had practiced mixed feeding changed to formula feeding. This trend demonstrates an increase in the rate of breast feeding at 3 months compared to a similar study done in 1999. The main reasons for discontinuing breast feeding were insufficient amount of milk(35.0 percent) and return to work(27.5 percent). Conclusion : Breast feeding rate has increased in Korea since 1999 but failure to continue exclusive breast feeding still occurs mainly within the first month after delivery. Breast feeding education should focus on supportive care to mothers practicing mixed feeding.

Comparison of various methods of glomerular filtration rate measurements in children (소아 환아에서 다양한 사구체 여과율 측정법의 비교)

  • Lee, Na Mi;Lim, In Seok
    • Clinical and Experimental Pediatrics
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    • v.52 no.9
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    • pp.999-1004
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    • 2009
  • Purpose : Glomerular filtration rate (GFR) is a fundamental parameter in assessing renal function and predicting the progression of chronic renal disease. Because the use of serum creatinine has several disadvantages, many studies have investigated the use of cystatin C for estimating GFR. We compared creatinine clearance and GFR with formulas using serum creatinine and cystatin C. Methods : We retrospectively analyzed 211 patients with various renal diseases and classified them into two groups according to creatinine clearance (Group 1: CrCl >$90mL/min/1.73m^2$, Group 2: CrCl <$90mL/min/1.73m^2$). We measured serum creatinine, cystatin C, and creatinine clearance. We calculated GFR using the Schwartz, Counahan, Filler and Lepage, Bokencamp et al, and Grubb et al formulas. Results : GFR determined by the Schwartz formula had the highest correlation to creatinine clearance (r=0.415, P=0.00). GFR determined by various formulas using cystatin C had lower correlation to creatinine clearance (r=0.187, r=0.187, r=0.291). The Schwartz and Counahan formulas showed greater diagnostic accuracy in detecting decreased GFR than cystatin C in group 2 (areas under the curve: Schwartz, 0.596; Counahan, 0.572; Filler, 0.512; Bokencamp, 0.508; and Grubb, 0.514). Conclusion : GFR determined by the Schwartz and Counahan formulas using serum creatinine showed higher correlation coefficient than that determined by formulas using cystatin C. The formulas using cystatin C were not superior to those using serum creatinine in detecting decreased GFR. Cystatin C measurement was not satisfactory for assessing GFR in patients whose renal function was not severely decreased.

A case of lethal kwashiorkor caused by feeding only with cereal grain (미음 수유만으로 발생한 치명적인 Kwashiorkor 1례)

  • Lee, Hyun Ju;Km, Kyung Hye;Park, Hye Jin;Lee, Kye Hyang;Lee, Gyeong Hoon;Choi, Eun Jin;Kim, Jin Kyung;Chung, Hai Lee;Kim, Woo Taek
    • Clinical and Experimental Pediatrics
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    • v.51 no.3
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    • pp.329-334
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    • 2008
  • Kwashiorkor is a syndrome of severe protein malnutrition, which manifests itself in hypoalbuminemia, diarrhea, dermatitis, and edema. It can be life-threatening due to associated immune deficiency and an increased susceptibility to infections. Kwashiorkor should be treated early with nutritional support and the control of infection. Dilated cardiomyopathy may develop during the treatment and in such cases a poor prognosis is expected. Kwashiorkor has been known as a common disease of poor countries. To date, in fact, there has been no report of kwashiorkor leading to death in technically advanced countries. We here report a fatal case of a baby girl admitted with kwashiorkor. She had been fed only with cereal grain mixed with juice, without any protein supplement, for 2 months. This diet was deficient not because of poverty, but due to the illiteracy of her parents. The patient suffered from diarrhea, whole body edema, hypothermia, and dermatitis. Laboratory findings revealed an immune-deficient state featuring leukopenia and decreased immunoglobulin. Blood and urine cultures revealed Alcaligenes Xylosoxidans growth. The patient was fed frequent small amounts of protein-containing formula and intravenous albumin and micronutrients were administered for nutritional support. She was also treated with intravenous immunoglobulin and antibiotics in order to control infection. Nevertheless, she developed dilated cardiomyopathy and multi-organ failure and died. We review this case in light of the literature.

Experimental Investigation of the Drag Coefficient of Porous Road Signs (유공형 도로표지의 항력계수에 대한 실험적 연구)

  • Sung, Hongki;Chong, Kyusoo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.2
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    • pp.71-76
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    • 2018
  • Recently, various technologies have been developed for road facilities to reduce the load, some of which use technologies employing perforated plates for wind load reduction. Currently, there are no regulations concerning the drag coefficient of perforated plates for domestic road facilities. In the United States, the regulations regarding the drag coefficient of perforated plates in the 'Minimum design loads for buildings and other structures' were revised based on the studies of Letchford (2001) and Giannoulis (2012). In this study, a wind tunnel test was carried out to analyze the feasibility of applying regulations involving the perforated plates' drag coefficient. The results of the wind tunnel test and the drag coefficient used in the regulation were compared and analyzed. In addition, the reduction effect of the cross area of road signs calculated by applying the drag coefficient was analyzed. The results of the wind tunnel test and the value of the drag coefficient used in the regulation in the US were found to be very similar. Therefore, it was found that it is possible to apply the formula involving the drag coefficient of the perforated plate to the regulation and that the cross area of the perforated plate used for the post of the road sign is reduced by about 9.45% and that of the horizontal post by about 6.45%.

Hydraulic Characteristics of Anaerobic Fluidized Bed Bioreactor (혐기성 유동상 반응기의 수리학적 특성)

  • Seok, Jong-Hyuk
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.2
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    • pp.90-96
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    • 2018
  • Tracer experiments were carried out on two laboratory modes, "without media mode" and "with media mode", to examine the hydraulic characteristics of the anaerobic fluidized bed bioreactor (AFBR). For both configurations, a formula was derived for the hydraulics and data interpretation to obtain the actual characteristics of the reactor. The dispersion model is based on the assumption that carriers are non-reacting and the dispersion coefficient is constant. The model represents the one-dimensional unsteady-state concentration distribution of the non-reacting tracer in the reactors. The experimental results showed that the media increased the mixing conditions in the reactor considerably. For the reactor without media, in the range tested, the dispersion coefficient was at least an order of magnitude smaller than that of the reactor with media. Advective transport dominates and the flow pattern approaches the plug flow reactor (PFR) regime. The dispersion coefficient increased significantly as us, the superficial liquid velocity, was increased proportionally to 0.82cm/s. On the other hand, for the reactor with media, the flow pattern was in between a PFR and a completely mixed flow reactor (CMFR) regime, and the dispersion coefficient was saturated at us=0.41cm/s, remaining relatively constant, even at us=0.82cm/s. The dispersion coefficient depends strongly on the liquid Reynolds number (Re) or the particle Reynolds number (Rep) over the range tested.

Arsenic removal from artificial arsenic water using CaAl-monosulfate and CaAl-ettringite (CaAl-monosulfate와 CaAl-ettringite를 이용한 인공비소폐수의 비소 제거 연구)

  • Shim, Jae-Ho;Kim, Ki-Baek;Choi, Won-Ho;Park, Joo-Yang
    • Journal of Korean Society of Water and Wastewater
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    • v.26 no.1
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    • pp.141-148
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    • 2012
  • The objective of this study is to remove arsenate from artificially contaminated wastewater using CaAl-ettringite and CaAl-monosulfate which were synthesized in laboratory. The study was carried on the basis of solidification/stabilization of waste using cement. Monosulfate and ettringite are constituents of cement paste. The CaAl-ettringite has a chemical formula of $Ca_6Al_2O_6(SO_4)_3{\cdot}32H_2O$ and has a needle like morphology. Whereas CaAl-monosulfate $Ca_4Al_2O_6(SO_4){\cdot}12H_2O$ has layered double hydroxide structure (LDH) in which the mainlayer consists of Ca and Al and S as interlayer. Ettringite and monosulfate were synthesized by reaction of tricalcium aluminate and gypsum and hydrating this mixture at elevated temperature. The synthesized mineral were characterized by PXRD and FESEM to ensure purity. It was found that concentrations of As(V) in contaminated water were reduced from initial concentration of 1.335 mmol/L to 0.054 mmol/L and 0.300 mmol/L by CaAl-monosulfate and CaAl-ettringite respectively. The post experimental results of PXRD and FESEM analysis indicate that arsenate removal was by ion exchange.

Filtering Rate Model of Farming Oyster, Crassostrea gigas with effect of Water Temperature and Size (수온과 크기의 영향을 고려한 양식굴, Crassostrea gigas의 여수율 모형)

  • KIM Yong-Sool
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.28 no.5
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    • pp.589-598
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    • 1995
  • Filtering rates of Crassostrea gigas were experimentally investigated with reference to effects of water temperature and size. Absorptiometric determinations of filtering rates with oysters being fed diatom Chaetoceros calcirtans were carried out in a closed system. Optical density of 675nm in path length 100mm cell used as the indication of food particles absorption was appeared directly In proportion with the concentration of diatom pigment $chlorophyll-\alpha$. In the closed system where $C_0$ is $OD_{675}$ at initial time 0, $C_t$, at time t, and Z is the decreasing coefficient of OD as meaning of instantaneous removal speed, then $C_t=C_0{\cdot} e^{-2t}$, $Z=In(C_t/C_0)/t$. On the assumption that the filtering rate is constant, then removal rate per unit time (d) is $d=-e^{-z}$. If t is used to time unit of hour (hr), the filtering rate (FR) in I/hr is given by $FR=V{\cdot}d=V(1-e^{-z})$, where V is the water volume (I) of the experimental vessel. Filtering rate increased as exponential function with increasing temperature while not over critical limit. The critical temperature for filtering rate was assumed to be between $28^{\circ}C$ and $29^{\circ}C$. And the weight exponent for filtering rate is 0.223. The model formula derived from the results as FR, $Ihr^{-1}$ = $Exp(0.208{\cdot}T-4.324){\cdot} (DW)^{0.223}$ (T<29 $^{\circ}C)$ where T is water temperature $(^{\circ}C

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An Experimental Study on Quality Properties of High Strength Concrete by the Replacement ratio Meta-kaolin Usable as Substitutes of Silica-fume (실리카흄 대체재로 활용 가능한 메타카올린의 치환율에 따른 고강도 콘크리트의 품질특성에 관한 실험적 연구)

  • Lee, Seung-Min;Lee, Ji-Hwan;Lee, Jong-Suk;Kim, Jae-Hwan;Lee, Sang-Soo;Song, Ha-Young
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.11a
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    • pp.333-336
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    • 2008
  • As the high-rise building increase due to the gravitation of population to big cities recently, it requires high quality and high performance of Concrete. As a result, people are keenly interested in Meta-kaolin as new admixture favorable from an economic perspective, which has strength and endurance with admixture at the same level like Silicafume. Accordingly, as to Meta-kaolin, this study was to set by three levels like domestic one, foreign one, and Silicafume, the waterbinding material ratio 25%, and four level substitute like 0, 10, 20, and 30(%) in order to compare and analyze the quality characteristics of high-strength concrete according to the substitute of Meta-kaolin applicable with replacement of Silicafume. As a result of performing experiment, as to the higher the additive amount of Superplasticizing agents in order to secure target liquidity was, the more the substitute in each admixture increased. This study had a tendency that the Silicafume increased the additive amount of Superplasticizing agents with high fineness compared with Meta-kaolin. In addition, the higher the substitute in each admixture was, the more its strength increased On the strength property, the higher the substitute in each admixture was, the more its strength increased. This study has found out that the Meta-kaolin has shown the better strength than the one of Silicafume. On the other hand, the relationship between the Compressive strength and Elastic coefficient has shown the similar formula suggested from ACI363.

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Sungshim-san-mediated Recovery of Cognition and Motor Function in the Severe Rat Stroke, Permanent Middle Cerebral Artery Occlusion Model (성심산(醒心散)의 중대뇌동맥 폐쇄로 유발된 허혈성 뇌손상 백서(白鼠)에 대한 인지 및 운동기능 회복 촉진효과)

  • Lee, Kyung-Seok;Chung, Dae-Kyoo
    • Journal of Oriental Neuropsychiatry
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    • v.26 no.3
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    • pp.319-336
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    • 2015
  • Objectives: The object of this study was to evaluate the cognition and motor function recovery effects of Sungshim-san (SSS), a traditional Korean cardio-protective polyherbal formula in the severe rat stroke, permanent middle cerebral artery occlusion (pMCAO) model. Methods: The experimental animals were divided into 6 groups. SSS aqueous extracts (yield=16.82%; 400, 200 and 100 mg/kg) were administered orally by using Sonde, once daily, for 28 continuous days from 24 hrs post-pMCAO. Donepezil 10 mg/kg, a representative drug for dementia, was used as a reference drug. The body weight changes, infarct/defect sizes, sensorimotor function and cognitive motor behavior were serially monitored. Limb placing and body-swing test for sensorimotor functions were conducted at 1 day before operation (base line), and 1, 3, 7, 14, 21 and 28 days post-pMCAO; and water maze test for the cognitive motor behavior was conducted at 14 and 28 days post-pMCAO, respectively. Results: Focal cerebral cortex infarct and defects due to pMCAO resulted in marked decreases of body weight, disorders of sensorimotor functions and cognitive motor behaviors. However, the pMCAO-related ischemic damages were markedly and dose-dependently inhibited by treatment with SSS 400 and 200 mg/kg, respectively. Donepezil markedly decreased the body weight and gains, as compared with pMCAO control rats; however, SSS 400 and 200 mg/kg favorably ameliorated the pMCAO-induced decreases in body weight and gains. SSS 100 mg/kg treated rats did not show any favorable effects on the pMCAO-related ischemic damages, as compared with pMCAO control rats. Conclusions: The results of the study indicated that oral administration of SSS 400 and 200 mg/kg accelerated cognition and motor function recovery in the rat pMCAO model. The treatment effect was potentially mediated by neuroprotection via the known augmentation of cerebral antioxidant defense system of SSS itself or its individual herbal components. Especially, the overall effects of SSS 200 mg/kg were similar to those of donepezil 10 mg/kg, but less toxic.