• Molecules and Cells
• /
• v.45 no.2
• /
• pp.76-83
• /
• 2022

Neurons-on-a-Chip technology has been developed to provide diverse in vitro neuro-tools to study neuritogenesis, synaptogensis, axon guidance, and network dynamics. The two core enabling technologies are soft-lithography and microelectrode array technology. Soft lithography technology made it possible to fabricate microstamps and microfluidic channel devices with a simple replica molding method in a biological laboratory and innovatively reduced the turn-around time from assay design to chip fabrication, facilitating various experimental designs. To control nerve cell behaviors at the single cell level via chemical cues, surface biofunctionalization methods and micropatterning techniques were developed. Microelectrode chip technology, which provides a functional readout by measuring the electrophysiological signals from individual neurons, has become a popular platform to investigate neural information processing in networks. Due to these key advances, it is possible to study the relationship between the network structure and functions, and they have opened a new era of neurobiology and will become standard tools in the near future.

• Journal of Information Processing Systems
• /
• v.20 no.4
• /
• pp.432-441
• /
• 2024

To improve the security of gene information and the accuracy of matching, this paper designs a homomorphic encryption algorithm for gene matching based on cloud computing environment. Firstly, the gene sequences of cloud files entered by users are collected, which are converted into binary code by binary function, so that the encrypted text is obviously different from the original text. After that, the binary code of genes in the database is compared with the generated code to complete gene matching. Experimental analysis indicates that when the number of fragments in a 1 GB gene file is 65, the minimum encryption time of the algorithm is 80.13 ms. Aside from that, the gene matching time and energy consumption of this algorithm are the least, which are 85.69 ms and 237.89 J, respectively.

• International Journal of Internet, Broadcasting and Communication
• /
• v.16 no.3
• /
• pp.321-328
• /
• 2024

This paper designs a disease prediction algorithm to diagnose migraine among the types of diseases in advance by learning algorithms using machine learning-based time series analysis. This study utilizes patient data statistics, such as electroencephalogram activity, to design a prediction algorithm to determine the onset signals of migraine symptoms, so that patients can efficiently predict and manage their disease. The results of the study evaluate how accurate the proposed prediction algorithm is in predicting migraine and how quickly it can predict the onset of migraine for disease prevention purposes. In this paper, a machine learning algorithm is used to analyze time series of data indicators used for migraine identification. We designed an algorithm that can efficiently predict and manage patients' diseases by quickly determining the onset signaling symptoms of disease development using existing patient data as input. The experimental results show that the proposed prediction algorithm can accurately predict the occurrence of migraine using machine learning algorithms.

• Science of Emotion and Sensibility
• /
• v.13 no.3
• /
• pp.467-474
• /
• 2010

Recently, Study of functional clothing for Vital sensing is focused on reducing artifact by human motions, in order to enhance the electrocardiogram(ECG) sensing accuracy. In this study, considering the factors for each element found from the analysis, a 3-lead electrode inside textile embroidered with silver yarn was developed, and draft designs off our types of vital-signal sensing garments, which are 'chest-belt typed' garment, 'cross-typed' garment 'x-typed' garment and 'curved x-typed' garment, were prepared. The draft designs were implemented on a sleeveless male shirt made of an elastic material so that the garment and the electrodes can remain closely attached along the contour of the human body, and the acquired data was sent to the main computer over a wireless network. In order to evaluate the effects caused by body movements and the ECG-sensing capability for each type in static and dynamic states, displacements were measured from one and two dimensional perspectives. ECG measurement evaluation was also performed for Signal-to-noise ratio(SNR) analysis. Applying the experimental results, the draft garment designs were modified and complemented to produce two types of modular approaches 'continuous-attached' and 'insertion-detached' for the ECG-sensing smart clothing.

• Journal of the Korean Institute of Landscape Architecture
• /
• v.43 no.6
• /
• pp.138-149
• /
• 2015

In order to search for the reasonable planning directions for representing traditional landscape, this study conducted the comparative analysis of the designs on the panels and their constructions from both winners of "The Landscape Design Competitions for City Infrastructure of Minlak(2) District in Uijeongbu" and "The Design Competition for Dongtan(2) District Land Development Phase 1". The representing targets and views, the composition and placement of representing space, the design of representing facilities and landscape planting were examined based on the text, master plans, elevations and cross sections, diagrams, images, and perspective drawings proposed from the competition panels. Then, the landscape constructions were reviewed. The results are as follows: First, the types of the representing targets and views are the agricultural landscape, as the local landscape of target area, which are divided into the life space of a traditional village, the traditional water space, and the traditional culture. Second, as to the composition and placement of representing space, the traditional theme spaces are formulated considering the surrounding land use and the local cultural heritage. However, some spaces were changed to the exercise space or convenient facility spaces required in a neighborhood park. Third, in the case of the representing facilities, a round island in the square pond, a traditional pavilion and Hwagye(terraced flower bed) were made without the facilities designed creatively. Fourth, the application of traditional planting techniques was focused on planting trees in the village forest on an island in the square pond and on Hwagye. Fifth, the traditional representing work has gradually advanced with the selection of subject and experimental facility designs based on the professional references. Sixth, the choice of the realizable subject, the expertise for information analysis and the creative design of the traditional facility are required in the future.

• Journal of the Korea Fashion and Costume Design Association
• /
• v.5 no.2
• /
• pp.75-91
• /
• 2003

This study analyzed descriptions about dots, lines, and sides which are used as a basic elements to express geometric figures as followings: -In the aspect of formative art, dots form images and feelings through their concurrence when make a slight move to coordinates. The concurrence can bring out either positive or negative images; -Lines have unlimited variation as a core measure in body art. They can make optimal effects with different lines such as straight and curved lines of human body; -Sides express not only effects of texture and perspective but also of space and solid by color effects. Expressive characteristics and geometric shapes can be classified by tattoo, henna and body painting: First, colorful tattoos are favored by Caucasian and original tattoos are mostly used by yellow and colored races in the way of scarification to get decorative effects. Recently, a rapid cycle of fashion change in tattoo figures has developed a tentative method of tattooing and a variety of decoration methods. It has made it a lot easier to change a pattern of a tattoo. Tattoos are now popular among people because they no longer have to suffer from pains when they get their body tattooed for a long time. Since tattoos boast their unique beauty which consists of most dynamic and attractive images among the types of body art. It will be one of the most favored make-up methods in the nearest future. Second, geometric designs used in henna include crosses, dots, straight lines, triangles, date palms, and so on. Henna has been particularly loved as an instant decoration by the public since it gradually disappears as time goes on. Third, body painting enables to draw a three-dimensional effect because of its close relation with body movements in a limited space. Each individual will have a different feeling appealed in their body painting. Body painting has been applied to many different areas, especially to theatrical art using lights, music and performance altogether producing impromptu and experimental works. Unlike other arts such as painting, sculpture, visual and industrial arts, body painting has mobility. Since it is painted on a three-dimensional human body, it can bear originality expressing realistic objects or animals and strengthen creative functions using body lines. Moreover, geometric designs can be diversified by the sexes. As a result of analysis, geometric designs expressed in body art seemed to transcend expressions of beauty and turned out to be another way of decoration. Body art has also been used as a way to express visual integration and consolidation dynamically not by human instinct but by social changes. The needs for body art will grow as the future comes nearer and be recognized as a new and fresh value. Formative elements of geometric figures deliver visual impressions combined with human body and finally create more various types of body art in harmony of body lines.

• Journal of Bio-Environment Control
• /
• v.28 no.3
• /
• pp.225-233
• /
• 2019

In the summer season, natural ventilation is commonly used to reduce the inside air temperature of greenhouse when it rises above the optimal level. The greenhouse shape, vent design, and position play a critical role in the effectiveness of natural ventilation. In this study, computational fluid dynamics (CFD) was employed to investigate the effect of different roof vent designs along with side vents on the buoyancy-driven natural ventilation. The boussinesq hypothesis was used to simulate the buoyancy effect to the whole computational domain. RNG K-epsilon turbulence model was utilized, and a discrete originates (DO) radiation model was used with solar ray tracing to simulate the effect of solar radiation. The CFD model was validated using the experimentally obtained greenhouse internal temperature, and the experimental and computed results agreed well. Furthermore, this model was adopted to compare the internal greenhouse air temperature and ventilation rate for seven different roof vent designs. The results revealed that the inside-to-outside air temperature differences of the greenhouse varied from 3.2 to $9.6^{\circ}C$ depending on the different studied roof vent types. Moreover, the ventilation rate was within the range from 0.33 to $0.49min^{-1}$. Our findings show that the conical type roof ventilation has minimum inside-to-outside air temperature difference of $3.2^{\circ}C$ and a maximum ventilation rate of $0.49min^{-1}$.

• Journal of The Korean Association For Science Education
• /
• v.23 no.2
• /
• pp.200-213
• /
• 2003

This study is one of the successive studies for investigating students' processes of generating and evaluating scientific hypothesis. In this study, I analyzed the characteristics of students' experimental design to test whether the given hypotheses were correct or not. As results, it was found that (1) 3 components (experimental method, prediction of the result of experiment, evaluation of hypothesis) were needed to complete description of the experimental design, (2) students tried to test hypothesis considered as being correct as well as hypothesis considered as being false by students, (3) student tried to confirm hypothesis, which was considered as being correct, based on theoretical approach rather than experimental approach, (4) students' experimental design could be classified as two types, that is, direct experimental testing and comparative experimental design, and the latter could be classified as two subtypes; positive comparative one and negative comparative one, (5) students showed tendency to design positive comparative experiment when they considered hypothesis as being correct, and vise versa, (6) students preferred the prediction which could confirm the hypothesis when they considered the hypothesis as being correct, and vise versa, (7) many students rejected contradicting prediction even though they did not actually conduct experiment yet.

• The Korean Nurse
• /
• v.34 no.5
• /
• pp.68-81
• /
• 1996

In order to see the development of nursing related research activities in Korea over the last three decades, abstracts of almost all of the Masters and Ph. D. theses that had appeared from 1961 up to August 1991 were collected. Number of theses amounted to 1779(76%) out of a total of 2354 theses. We analysed the papers research patterns, which are research problem, research design, population, place. Here is what we have found. 1). The types of research problems were as follows. 58.0% papers did factor-analysis, 29.1% studied factor~relations, 11.4% situation relations and 1.5% did situation~creations. With respect to the years, we found that the factor-analysis papers decreased with time but the factor~relating, the situation -relating, and the situation~creating papers were increased. Especially the situation-creating paper increased notably since the 80s'. Relating to the kind of degrees, we found that for M.S.theses 60.2% of the papers did factor-analysis, 29.0% the factor-relating studies, 10.4% the situation-relating studies, and 0.4% the situation -creating studies. For the Ph.D. theses 30.5% did the factor~relating, 30.5% the situation-relating. and 20.0% the situation-creating papers. Considering the graduate schools, we found that the regular graduate schools and the graduate school of education produced about the same number of papers of each kind, but 81.2% and 64.6% papers produced by the graduate school of public health and the graduate school of public administration, respectively, did the factor-analysis thus taking majority of the papers. 2). Research designs were as follows : 10.8% experimental studies, 89.0% non experimental studies, and 0.2% quality studies were found. So the majority of the research designs were nonexperimental. We see a meaningful difference between the M.S.theses showing 9.8% experimental studies and 90. 1% nonexperimental studies. and Ph.D. theses showing 28.4% experimental studies and 68. 4% nonexperimental studies. Relating to the graduate schools, we find that the regular graduate schools and the graduate school of education with 15.8% and 10.6% experimental studies respectively, did a little more experimental studies than other schools. but still the regular graduate schools, the graduate school of public health, and the graduate school of education each show 83.8%, 97.4%, and 89.4% nonexperimental studies, so most schools are concentrating on nonexperimental studies. 3). On the relation between research problem and research design, experimental studies show 88.0% of situation-relations and 6.8% of factor-relations. Nonexperimental studies had factor-analysis taking the majority by 64.4% and 31.9% were factor-relations. 4). On the research subjects, we have 90.8% of the papers dealing with a single subject and 9.2% of the papers dealing with two or more subjects. Most of the research subjects are patients or nurses for the regular graduate schools and the graduate school of education, but for the graduate school of administration as much as. 60% of the studies took nurses as subjects. Subjects taken were patients, nurses. and students in decreasing order for the M.S. theses and for patients, women, and nurses again in decreasing order for the Ph.D.theses. 5). On the places of study, we've had 47, 8% of the studies done in hospital rooms, 15, 1% in schools, and 9, 6% in the local community, With respect to the years, we found 36.7% in the hospital rooms, 22.4% in the schools, and 14, 8% in the local communities in the 1970's and 50.1%in the hospital rooms, 13.4% in the schools. and 9, 2% in the local communities in the 80's.

• Journal of Korean Society for Quality Management
• /
• v.50 no.1
• /
• pp.169-181
• /
• 2022

Purpose: This paper addresses a case study of developing a flame retardant wood-plastic composites (WPC) by adding tannic acid to the existing synthetic wood. The optimal mixing ratios of six components are explored to minimize the burning time using two mixture designs. Methods: In the preliminary experiment, six components are considered to find important components and their ranges. Seven D-optimal mixture design points are generated. Two points are removed for the balance of plastic components to be maintained, and the remaining five points are augmented with two basic compositions. Four components are selected to be considered in the main experiment. In the main experiment, pellets are extruded at the eight mixture design points. In-house testing of burning time is executed three times. Specimens made of pellets from two promising flame retardant compositions are sent to the accredited laboratories and tested. Results: The test results are as follows: 1) The best composition (Wood flour, Tannic acid, PE, Lubricant) = (25, 41, 10, 2) (wt%) shows the burning time of 1 second, which is 9-fold improvement compared to the the burning time of 9 seconds from the existing composition (58, 0, 10, 2) (wt%). 2) The second best composition (41, 25, 10, 2) (wt%) results in the burning time of 2 seconds. This composition is inferior to the best composition in terms of the flame retardancy, but more economical since it needs less tannic acid which is 100-fold expensive than the wood flour. Conclusion: Flame retardant compositions are found by adding tannic acid to the existing WPC employing optimal mixture designs. This case study will be helpful to practitioners who try to develop new products with additional physical properties with as small number of experimental trials as possible. Future research direction includes exploring conditions which satisfy both performance level and cost limitation simultaneously.