• Journal of Life Science
• /
• v.27 no.2
• /
• pp.211-216
• /
• 2017

This study aims to reduce the production cost of mushrooms and therefore boost the income of mushroom producers. The addition of a 10% concentration of herb medicine refuse was adequate for promoting mycelium growth in Flammulina velutipes. A moisture content of 60% in the culture medium was adequate for promoting hyphal growth. The optimum temperature and humidity were $16^{\circ}C$ and 70%-85%, respectively. The average yield of Flammulina velutipes fruting body per 1,100 ml bottle was 275-282 g, which is similar to that of the control. The outbreak of diseases such as mildew and bacterial blotch in mushroom was never observed in the bottle treated with herb medicine refuse. Fewer deformed and second-class quality mushrooms were observed than in the control group. Deviation reduced, and mushroom growth was observed to be significantly uniform. The winter mushroom had a white fruiting body with a hemispherical shape. The diameter of the mushroom cap was 9.2-9.3 mm, stipe length was 12.7-12.8 cm, and thickness was 3.3-3.4 mm; these were almost the same as those in the control group. The partial hardness of winter mushrooms in both the experimental and the control groups showed that the stipe ($54.6-57.3g/cm^2$) is a little harder than the mushroom cap ($46.8-47.6g/cm^2$). The calories and nutrients per 100 g of mushrooms in the control and samples were similar to each other.

• Journal of The Korean Association For Science Education
• /
• v.24 no.5
• /
• pp.805-813
• /
• 2004

Our educational system clearly places much greater value on left hemisphere learning. Students who process information in other ways are at a serious disadvantage and may not be learning efficiently. Since mind mapping emphasizing visual and spatial language, it helps students to use the whole brain and promotes more effective comprehension. The purpose of this research was to determine the effects of the instruction using mind map on the science achievement of students. A pretest-posttest control group design was employed. Subjects were 153 male and female, first grade students in a middle school. A control group of 83 was instructed with a traditional teaching method, and an experimental group of 70 was instructed by using a mind mapping strategy. Two groups were treated for 50 hours during 17 weeks. Tolerance's 'Style Of Learning And Thinking(SOLAT)' was used to assess students' lateralization preferences. A 30-item multiple choice posttest was used to assess students' achievement. To analyze the data, we used an analysis of covariance(ANCOVA) and i-tests. It was found that 21.6% of students was left brain dominant, 31.4%, right brain dominant and 47.1 % was integrated style. There was no gender difference in hemispheric dominance. Significant differences existed between the test scores when they were taught by using a mind map. Mind mapping turned out to be a valuable learning technique for the right brain students, helping them to achieve the same level of subject mastery as left brain students. There was a significant difference between males and females in relation to mind map application. Female scored significantly higher than males.

• Korean Chemical Engineering Research
• /
• v.53 no.2
• /
• pp.236-242
• /
• 2015

We present two data-driven modeling methods, partial least square (PLS) and artificial neural network (ANN), to predict the major operating and performance variables of a polymer electrolyte membrane (PEM) fuel cell stack. PLS and ANN models were constructed using the experimental data obtained from the testing of a 30 kW-class PEM fuel cell stack, and then were compared with each other in terms of their prediction and computational performances. To reduce the complexity of the models, we combined a variables importance on PLS projection (VIP) as a variable selection method into the modeling procedure in which the predictor variables are selected from a set of input operation variables. The modeling results showed that the ANN models outperformed the PLS models in predicting the average cell voltage and cathode outlet temperature of the fuel cell stack. However, the PLS models also offered satisfactory prediction performances although they can only capture linear correlations between the predictor and output variables. Depending on the degree of modeling accuracy and speed, both ANN and PLS models can be employed for performance predictions, offline and online optimizations, controls, and fault diagnoses in the field of PEM fuel cell designs and operations.

• Clinical and Experimental Reproductive Medicine
• /
• v.23 no.3
• /
• pp.269-275
• /
• 1996

Biosynthesis and secretion of anterior pituitary hormones are under the control of specific hypothalamic stimulatory and inhibitory factors. Among them, Growth Hormone Releasing Hormone (GHRH) is the major stimulator of pituitary somatotrophs activating GH gene expression and secretion. Human GHRH is a polypeptide of 44 amino acids initially isolated from pancreatic tumors, and the gene for the hypothalamic form of GHRH is organized into 5 exons spanning over 10 kilobases (kb) on genomic DNA and encodes a messenger RNA of 700-750 nucleotides. Several neuropeptides classically associated with the hypothalamus have been found in the extrahypothalamic regions, suggesting the existence of novel sources, targets and functions. GHRH-like immunoreactivity has been found in several peripheral sites, including placenta, testis, and ovary, indicating that GHRH may also have regulatory roles in peripheral reproductive organs. Furthermore, higher molecular weight forms of the GHRH transcripts were identified from these organs (1.75 kb in testis; 1.75 and >3 kb in ovary). These tissue-specific expression of GHRH gene suggest the existence of unique regulatory mechanism of GHRH expression and function in these organs. In fact, placenta-specific and testis-specific promoters for GHRH transcripts which are located in about 10 kb upstream region of hypothalamic promoter were reported. The use of unique promoters in extrahypothalamic sites could be refered in a different control of GHRH gene and different functions of the translated products in these tissues. Somatotrophs and lactotrophs have been thought to be derived from a common bipotential progenitor, the somatolactotrophs, which give origins to either phenotypes. Although the precise mechanism responsible for the lactotroph differentiation in the anterior pituitary gland has not been yet clalified, there are several candidators for the generation of lactotrophs. In human, the presence of GHRH peptides with different size from authentic hypothalamic form in the normal anterior pituitary and several types of adenoma were demonstrated. Recently our group found the existence of immunoreactive GHRH and its transcript from the normal rat anterior pituitary (gonadotroph> somatotroph> lactotroph), and the GHRH treatment evoked the increased proliferation rate of anterior pituitary cells in vitro. The transgenic mouse models clearly shown that GHRH or NGF overexpression by anterior pituitary cells induced development of pituitary hyperplasia and adenomas particularly GH-oma and prolactinoma. Taken together, we hypothesize that the pituitary GHRH could serve not only as a modulator of hormone secretion but as a paracrine or autocrine regulator of anterior pituitary cell proliferation and differentiation. Interestingly enough, the expression of Pit-1 homeobox gene (the POU class transcription factor) was confined to somatotrophs, lactotrophs and somatolactotrophs in which GHRH receptors are expressed commonly. Concerning the mechanism of somatolactotroph and lactotroph differentiation in the anterior pituitary, we have focused following two possibilities; (1) changes in the relative levels or interactions of both hypothalamic and intrapituitary factors such as dopamine, VIP, somatostatin, NGF and GHRH; (2) alterations of GHRH-GHRH receptor signaling and Pit-1 activity may be the cause of lactotroph differentiation or pituitary hyperplasia and adenoma formation. Extensive further studies will be necessary to solve these complicated questions.

• Korean Journal of Veterinary Research
• /
• v.41 no.2
• /
• pp.177-188
• /
• 2001

Mastitis is one of the most significant cause of economic loss to the dairy industry. Especially, Staphylococcus aureus is a major contagious mastitis-causing pathogen in dairy cattle. Because of its high transmission rate and resistance to antibiotic therapy, staphylococcal mastitis presents a constant threat to the dairy industry. Staphylococcal enterotoxin C(SEC) produced by S aureus has been known as one of superantigens which are able to stimulate a large proportion of T lymphocytes independently of their antigenic specificity. In this experiment, we have conducted preliminary studies with mice and lactating cows to evaluate the immunogenicity and safety of the experimental vaccine consists of SEC mutant antigen on controlling the bovine mastitis associated with S aureus infections. The average value of somatic cell counts in quarter milk, isolation rate of S aureus were consistently decreased in SEC-SER vaccinated groups, whereas antibody titers were highly increased in SEC-SER vaccinated groups. Peripheral blood were also collected from the lactating cows to determine the proportion of leukocyte subpopulation associated with humoral immunity(HI) and cell mediated immunity(CMI). Proportion of leukocyte subpopulation expressing $BoCD2^+$(total T lymphocyte), $BoCD4^+$(T helper cell), $BoCD8^+$(T cytotoxic/suppressor cell) and NonT/NonB lymphocyte which are involved in CMI in SEC-SER vaccinated groups were decreased for the initial stage after first vaccination and then increased from ten weeks after first vaccination maintaining elevated level till 14 weeks after vaccination. In contrast, proportion of monocyte, MHC class II and B lymphocyte which are associated with the production of primary immune response in SEC-SER vaccinated groups were increased for the initial period and then decreased from ten weeks after first vaccination. We present evidence that vaccination of SEC-SER mutant antigen in lactating cows induced a significant proliferation of bovine T lymphocytes. These results suggest that SEC-SER mutant antigen used in this experiment might be one of potential immunogen in developing innovative vaccine against bovine IMI associated with S aureus. Additional challenge trials should be carried out to evaluate substantial protection against S aureus under the commercial farm conditions.

• Journal of Gifted/Talented Education
• /
• v.26 no.1
• /
• pp.77-99
• /
• 2016

The purpose of this study was to examine the effect of GI-STEAM program on leadership, creative personality, and learning flow of elementary Gifted Students. GI-STEAM program was the convergence model of Group Investigation that belongs to Co-learning and STEAM framework of learning criterion. The participants were 16 gifted students in a Korean elementary school located in Gyeong-gi province. The experimental design was one group pretest-posttest design. After a pretest on leadership, creative personality, and learning flow was conducted, classes were carried out as GI-STEAM program for the gifted student and a post-test was conducted. The study results of the class that was conducted twelve times for two weeks are as follows. First, Individual area of leadership is meaningfully developed in statistics after GI-STEAM program. The sub-domains of leadership, such as the communication, organization management, society commitment and teamwork showed a statistically significant improvement. Second, the domain of creative personality didn't show meaningful difference after GI-STEAM program. However, the aesthetic in the sub-domains of the creative personality showed a statistically significant improvement. Third, learning flow was meaningfully developed in statistics after GI-STEAM program. The sub-domains of the leadership, such as the balance between challenge and ability, integration with behavior and consciousness, concrete feedback and Autotelic experience showed a statistically significant improvement. In conclusion, GI-STEAM is an effective program for improving ability of communication, aesthetic sensibility, which are core competency of 'creative-convergence' gifted students. For this reason, it is highly considered that various programs applying GI-STEAM should be developed.

• The Journal of the Korea Contents Association
• /
• v.18 no.6
• /
• pp.353-363
• /
• 2018

According to the Digi Capital forecast, the global augmented reality market is expected to grow rapidly by 2020 to reach 150 billion dollars. In particular, high value added effects are expected in education. As ICT advances, digital textbooks are also leading innovative education by adding interactive functions. Advanced countries, including the U.S., are already using digital textbooks that use augmented reality technology in their classes. In line with this technological outlook, the ministry proposed a design plan that applies augmented reality technology to middle school science 1 digital textbooks. A study on middle school science 1 digital textbooks showed that each unit provided short videos. In addition, an investigation into the augmented reality class case showed that it was difficult to establish experimental equipment, lack of equipment (devices), and 3D design contents that did not continue despite the excellence of learning effects. Based on this demand, we designed an augmented reality scenario and system configuration to be applied to the instrument-specific experiments of middle school science 1 digital textbooks to explore and explore the contents of augmented reality by students. This research will replace the dangerous experiments and time consuming experiments for teachers and students by applying augmented reality to science subjects that are essential for the development of digital textbooks.

• Restorative Dentistry and Endodontics
• /
• v.12 no.1
• /
• pp.119-129
• /
• 1986

The purpose of this study was to evaluate the marginal leakage of glass ionomer cement with different cavosurface margins. 192 class V cavities were prepared on freshly extracted non-carious teeth and glass ionomer cement were inserted according to the manufacturer's instructions. Cavity preparations for this investigation were performed in four groups. The experimental specimens were made by packing the glass ionomer cement (Fuji Ionomer Type II G-C Co. Japan) into the prepared 192 cavities of four groups with different modes: Group I. - The 48 cavities with $90^{\circ}$ butt-joint cavosurface preparation and restored with glass ionomer cement. Group II. - The 48 cavities with butt-joint preparation modified by $135^{\circ}$ beveling the cavosurface in the dentin and restored with glass ionomer cement. Group III. - The 48 cavities with butt-joint preparation modified by cutting a chamfer in the dentin and restored with glass ionomer cement. Group IV. - The same 48 cavities as group I, and overfilled with glass ionomer cement beyond the cavosurface angle. And four groups above described divided into three subgroups by means of conditioning the cavity walls: Control group. - Glass ionomer cement filled in the prepared 64 cavities after being cleaned with a stream of tap water. Phosphoric acid treatment group. - Glass ionomer cement filled in the prepared 64 cavities after being conditioned with a 50% phosphoric acid. Citric acid treatment group. - Glass ionomer cement filled in the prepared 64 cavities after being conditioned with a 50% citric acid. All 192 specimens were immersed in the 2.0% basic fuchsin solution and subjected to thermal stress at one-minute intervals ($4{\pm}2^{\circ}C$ to $60{\pm}2^{\circ}C$) for 70 minutes before exposure to the dye. The specimens were sectioned ecclesiologically through the center of the restorations for different periods of immersion time, 24 hours, 7 days, 14 days 30 days. The sections were examined under a stereoscopic microscope. The results were as follows: 1. The degree of marginal leakage in group II and III was greater than that in group I and IV. 2. The degree of marginal leakage in phosphoric acid treatment group was similar with that in control group. 3. The degree of marginal leakage in citric acid treatment group was less than that in control group. 4. In all groups, the degree of marginal leakage in phosphoric acid treatment group was greater than that in citric acid treatment group. 5. There is no statistical difference of the degree of marginal leakage according to the immersion time in the dye solution.

• Journal of Korean Society of Forest Science
• /
• v.76 no.1
• /
• pp.17-26
• /
• 1987

To develop the rehabilitation measures for rockily denuded forest lands which are widely distributed in Seoul metropolitan area, erosional characteristics of denudation should, first of all, be evaluated and analysed. As a fundamental study for developing such technical measures, the rockily denuded lands were classified into 6 types according to denudation features of the mountain land, and also movements of stone debris-and-sand on rock-exposed hillslopes were measured and analysed. The 6 basic types of denudation features include a) natural rock-outcrop-exposed land, b) stone debris-and-sand scattered land, c) stone debris-and-sand deposited land, d) coarse sand producing bare land susceptible to weathering and erosion, e) dwarfed pine growing land, and f) torrential valley susceptible to the debris slides. In the stone debris-and-sand scattered hillslopes (type b), average amount of moved-down debris reached to about 3.9 ton/ha/yr due to surface washing and slidings. In the particle size distribution of the moved-down debris, it amounts to about 25% of 10-25mm, about 15% of 5-10mm, about 24% of 2-5mm, and about 36% of less than 2mm in diameter class, respectively. The detailed experimental studies should be accomplished further more about the denudation processes including weathering, erosion and debris slides on rock-exposed hillslopes.

• Journal of Korean Society of Forest Science
• /
• v.98 no.3
• /
• pp.247-254
• /
• 2009

In this study, linear programming was applied to a case study in Gwangreung Experimental Forest of Korea Forest Research Institute investigating the effect of the desired future conditions on forest management. Considering the social, economic and ecological demands of people from the forest, the forest functions were classified into four including natural conservation, timber production, water yield and scenic conservation. The forest land areas were divided into four-types of forest functional zones and forest management prescriptions including the desired future conditions by the forest function type were established. The Model II linear programming was used in optimizing the forest management planning. The model includes management policies, as the constraints, for non-declining yield, allowable cutting area, allowable % age class distribution and allowable % species allocation as well as the land and other accounting regimes. Maximization of timber production was used the objective function. Based on the Model II formulations, the effects of the desired future conditions by the forest function type on forest management planning were investigated in terms of timber production, net present value and stand structures over time.