• Title/Summary/Keyword: Experimental Research

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The Trend and Issues of Nursing Research Related to Ischemic Heart Disease Published in Korea (허혈성심질환 관련 국내 간호연구 동향)

  • Lee, Jong-Yul;Lee, Hyang-Yeon
    • Journal of East-West Nursing Research
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    • v.8 no.1
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    • pp.89-102
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    • 2003
  • This study attempted to analyze the trend of studies related to IHD(Ischemic Heart Disease). This article reviewed 102 researches on IHD conducted from 1980 to 2003, by examining them according to their characteristics, such as sources by publication period, research design, nursing intervention, outcome of experimental research, and theme of qualitative research. The results were as follows : 1. The number of studies related to IHD has steadily increased year by year since 1985, and that of the articles was the highest during the post-2000 period. Especially, the majority of researches has published since 1995. 2. The 69 studies were degree of all 102 studies related to IHD, and the majority of articles' authors belonged to graduate school. Thirty three studies were non-degree articles. As for study design, the number of quantitative studies were 99 and that of qualitative studies were 3. Non-experimental research design were largely survey and correlational study. 3. Non-experimental study makes up a high proportion of the quantitative study. The most of experimental studies were accomplished after 2000. The main subjects were patients, chart records and general subjects. The majority number of subjects was like this : while the number of non-experimental study was between 51 and 100, that of experimental study was below 50. The number of subject of qualitative study is like this : the number of phenomenology study was 21 and 11, and that of case study is 14. 4. Nursing interventions used in the experimental study comprised teaching program, cardiac rehabilitation program, massage, relaxation, music therapy and providing of sense information. And the most nursing intervention effects included physiological effect, increased self-efficacy, relieved pain and increased quality of life. Most studies proved to have the affirmative effects. 5. The number of qualitative studies related to IHD is like this : the number of degree articles was 2 and that of non-degree articles was 1. Its themes included resources of hope, the experience of coronary artery angiography and the experience of admission at ICU(Intensive Care Unit).

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Flexural fatigue modeling of short fibers/epoxy composites

  • Shokrieh, M.M.;Haghighatkhah, A.R.;Esmkhani, M.
    • Structural Engineering and Mechanics
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    • v.64 no.3
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    • pp.287-292
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    • 2017
  • In the present research, an available flexural stiffness degradation model was modified and a new comprehensive model called "X-NFSD" was developed. The X-NFSD model is capable of predicting the flexural stiffness degradation of composite specimen at different states of stresses and at room temperature. The model was verified by means of different experimental data for chopped strand mat/epoxy composites under displacement controlled bending loading condition at different displacements and states of stresses. The obtained results provided by the present model are impressively in very good agreement with the experimental data and the mean value of error of 5.4% was achieved.

Sensitivity analysis of numerical schemes in natural cooling flows for low power research reactors

  • Karami, Imaneh;Aghaie, Mahdi
    • Advances in Energy Research
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    • v.5 no.3
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    • pp.255-275
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    • 2017
  • The advantages of using natural circulation (NC) as a cooling system, has prompted the worldwide development to investigate this phenomenon more than before. The interesting application of the NC in low power experimental facilities and research reactors, highlights the obligation of study in these laminar flows. The inherent oscillations of NC between hot source and cold sink in low Grashof numbers necessitates stability analysis of cooling flow with experimental or numerical schemes. For this type of analysis, numerical methods could be implemented to desired mass, momentum and energy equations as an efficient instrument for predicting the behavior of the flow field. In this work, using the explicit, implicit and Crank-Nicolson methods, the fluid flow parameters in a natural circulation experimental test loop are obtained and the sensitivity of solving approaches are discussed. In this way, at first, the steady state and transient results from explicit are obtained and compared with experimental data. The implicit and crank-Nicolson scheme is investigated in next steps and in subsequent this research is focused on the numerical aspects of instability prediction for these schemes. In the following, the assessment of the flow behavior with coarse and fine mesh sizes and time-steps has been reported and the numerical schemes convergence are compared. For more detail research, the natural circulation of fluid was modeled by ANSYS-CFX software and results for the experimental loop are shown. Finally, the stability map for rectangular closed loop was obtained with employing the Nyquist criterion.

Effects of Simple and Disposable Chicken Cages for Experimental Eimeria Infections

  • Yoo, Jeong-Mi;Kang, Sung-H.;Jeong, Jip-Seol;Kim, Woo-H.;Kim, Suk;Lillehoj, Hyun S.;Min, Won-Gi
    • Parasites, Hosts and Diseases
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    • v.49 no.3
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    • pp.299-302
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    • 2011
  • During experimental Eimeria infections in chickens, facilities are often contaminated by fecal oocysts known to be highly resistant to both chemical and enzymatic treatments. Thus, studies using experimental Eimeria infections have been limited due to the difficulty of complete elimination of residual oocysts from both cages and facilities. To overcome this limitation, simple, inexpensive, and disposable cages were constructed from cardboard boxes and tested during experimental Eimeria maxima infections. The cages were used in animal rooms with only a 1.7% evidence of coccidia contamination between adjacent cages. No significant differences in fecal oocyst output and body weight gain were noted between animals housed in disposable cages and animals housed in wire control cages. This cage design is a useful means for preventing oocyst contamination during experimental conditions, suggesting that this disposable cage design could be used for other avian infectious disease studies.

Effects of mixture of fibrin-fibronectin sealant system and calcuim carbonate in periodontal intrabony defects (calcium carbonate와 fibrin-fibronectin sealant system 혼합이식이 치주골내낭 치유에 미치는 영향)

  • Chang, Soo-Jin;Han, Dong-Kwan;Yun, Jeong-Ho;Jung, Ui-Won;Kim, Chang-Sung;Choi, Seong-Ho;Cho, Kyoo-Sung;Kim, Chong-Kwan;Chai, Jung-Kiu
    • Journal of Periodontal and Implant Science
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    • v.34 no.3
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    • pp.581-591
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    • 2004
  • Calcium carbonate(CC) is biocompatible and gradually absorb to be replaced by bone when implanted into bone tissue. Fibrin-fibronectin sealant system (FFSS) is a product of human-derived plasma. The effect is hemostasis, tissue fixation and adhesion, We expect synergic effects of this two materials in periodontal regeneration. When FFSS was grafted with bone graft in intrabony defects, could be eliminated exofolication of bone graft materials. This study evaluated above materials for periodontal regeneration of 6mm intrabony defects in 36 patients. lap surgery was carried in 14 defects of control group. experimental group 1 was 11 defects grafted with calcium carbonate, experimental group 2 was 11 defects which were grafted with calcium carbonate with FFSS. The clinical parameters evaluated included changes in attachment level, probing depth, gingival recession at 6 months. Postsurgery probing depth reduction was 3.1 ${\pm}$ 0.9mm in control, 3.8 ${\pm}$ 1.6mm in experimental group 1, 4.1 ${\pm}$ 1.1mm in experimental group 2. The result clinically and statistically improved compared to baseline(P<0.01), but the difference found among the groups were not statistically significant. Postsurgery clinical attachment level was 1.6 ${\pm}$ 1.2mm in control, 3.5 ${\pm}$ 2.0mm in experimental group 1, 3.3 ${\pm}$ 1.2mm in experimental group 2. All of the control and experimental groups resulted in a statistically significant reduction from baseline(P<0.01). The reduction of the experimental groups were statistically significant from control(P<0.05). But the change between experimental group 1 and experimental group 2 was not statistically significant. We conclude that mixture of CC and FFSS is effective to periodontal regeneration in intrabony defect.

The effect of newly designed toothbrush on plaque control, treatment of gingivitis and periodontitis (체스형의 칫솔모 형태가 치태 및 치은염, 치주낭에 미치는 영향)

  • Chai, Jung-Kiu;Shin, Chul-Woo;Suh, Jong-Gin;Choi, Seong-Ho;Cho, Kyoo-Sung;Kim, Chong-Kwan
    • Journal of Periodontal and Implant Science
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    • v.29 no.1
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    • pp.131-139
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    • 1999
  • The present study investigate the effect of newly designed toothbrush(Chess tip : experimental group), conventional toothbrush(control group) on plaque control, gingivitis, and periodontitis. The results of 4weeks post-research by clinical comparison between the two groups are as follows. 1. In analysis of plaque index between groups there was Significant difference in the experimental group at 2,4 week. 2. In analysis of gingival index between groups there was significant difference in the experimental group at 1,2,4 week. 3. Both experimental group and control group showed decrease in periodontal pocket depth after 4week, but there was significant difference in the experimental group at 4 week. 4. Both experimental group and control group showed decrease in bleeding on probing after 4week, but there was significant difference in the experimental group at 4 week. These results indicate that newly designed toothbrush has beneficial effects as additional aid of mechanical treatment at the point of periodontal pocket, plaque control, and bleeding on probing.

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Trend Analysis of Research Articles Published in the Korean Journal of Women Health Nursing from 2013 to 2017 (최근 4년간 여성건강간호학회지에 게재된 여성건강 관련 연구의 동향(2013~2017년))

  • Lee, Young Jin;Kim, Seo Yun;Kang, Saem Yi;Kang, Yoo Jeong;Jin, Lan;Jung, Hee Yoen;Kim, Hae Won
    • Women's Health Nursing
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    • v.24 no.1
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    • pp.90-103
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    • 2018
  • Purpose: To analyze articles published in the Korean Journal of Women Health Nursing from 2013 to 2017 to determine the latest research trends and understand how 2013 Korea Women's Health Statistics were reflected in journal articles. Methods: A total of 130 studies were analyzed. Research design, types of research, research framework, research subjects, characteristics of quantitative research, characteristics of qualitative research, and keywords were analyzed using a structured analysis format. Results: Quantitative and qualitative research accounted for 83.8% and 13% of these 130 studies analyzed, respectively. Non-experimental and experimental research accounted for 70.7% and 13.1% of these studies, respectively. The most frequent study subjects were childbearing women (62.8%), including college students, mothers, and adults. A total of 69.1% of non-experimental research and 88.2% of experimental research used convenience sampling. Questionnaires were most frequently used for data collection. The most frequent keyword domain involved health-related concepts (41%) among nine domains and the most frequently used keyword was "women." Conclusion: This study suggest that further experimental research should be conducted in the future. Also, adolescent and the elderly women should be focused on as subjects in future studies based on results of 2013 Korean Women's Health Statistics.

GUIDED BONE REGENERATION OF CALVARIAL BONE DEFECTS USING BIOABSORBABLE MEMBRANE AND DEMINERALIZED FREEZE DRIED BONE IN RATS (백서에서 흡수성막과 탈회동결건조골을 이용한 두개골결손부의 골재생)

  • Kim, Soo-Min;Yeo, Hwan-Ho;Kim, Su-Gwan;Lim, Sung-Chul
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.28 no.4
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    • pp.290-301
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    • 2002
  • The purpose of this study was to evaluate new bone formation and healing process in rat calvarial bone defects using $BioMesh^{(R)}$. membrane and DFDB. Forty eight rats divided equally into 4 groups of 1 control group and 3 experimental groups. Standardized transosseous circular calvarial defects (8 mm in diameter) were made midparietally. In the control group, the defect was only covered with the soft tissue flap. In the experimental group 1, it was filled with DFDB only, in the experimental group 2, it was covered $BioMesh^{(R)}$. membrane only, and in the experimental group 3, it was filled DFDB and covered with membrane. At the postoperative 1, 2, 4, 8 weeks, rats were sacrificed and histologic and histomorphometric analysis were performed. These results were as follows. In histomorphometric analysis, It showed the greatest amount of new bone formation through experimental in the experimental group 3 (P<0.001). The amount of new bone formation at the central portion of the defect was greater in the experimental group 3 than experimental group 2. $BioMesh^{(R)}$. membrane began to resorb at 1 week and resorbed almost completely at 8 weeks after operation. The collapse of membrane into the defect was observed through the experimental periods in the experimental group 2. In the area of collapsed membrane, new bone formation was restricted. These results suggest that maintenance of some space for new bone to grow is required in the use of $BioMesh^{(R)}$. membrane alone in the defect. It is also thought that use of the membrane may promote new bone growth in DFDB graft.

Effect of masonry infilled panels on the seismic performance of a R/C frames

  • Aknouche, Hassan;Airouche, Abdelhalim;Bechtoula, Hakim
    • Earthquakes and Structures
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    • v.16 no.3
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    • pp.329-348
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    • 2019
  • The main objective of this experimental research was to investigate the Seismic performance of reinforced concrete frames infilled with perforated clay brick masonry wall of a type commonly used in Algeria. Four one story-one bay reinforced concrete infilled frames of half scale of an existing building were tested at the National Earthquake Engineering Research Center Laboratory, CGS, Algeria. The experiments were carried out under a combined constant vertical and reversed cyclic lateral loading simulating seismic action. This experimental program was performed in order to evaluate the effect and the contribution of the infill masonry wall on the lateral stiffness, strength, ductility and failure mode of the reinforced concrete frames. Numerical models were developed and calibrated using the experimental results to match the load-drift envelope curve of the considered specimens. These models were used as a bench mark to assess the effect of normalized axial load on the seismic performance of the RC frames with and without masonry panels. The main experimental and analytical results are presented in this paper.

Research Progress of CXCR4-Targeting Radioligands for Oncologic Imaging

  • Yanzhi Wang;Feng Gao
    • Korean Journal of Radiology
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    • v.24 no.9
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    • pp.871-889
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    • 2023
  • C-X-C motif chemokine receptor 4 (CXCR4) plays a key role in various physiological functions, such as immune processes and disease development, and can influence angiogenesis, proliferation, and distant metastasis in tumors. Recently, several radioligands, including peptides, small molecules, and nanoclusters, have been developed to target CXCR4 for diagnostic purposes, thereby providing new diagnostic strategies based on CXCR4. Herein, we focus on the recent research progress of CXCR4-targeting radioligands for tumor diagnosis. We discuss their application in the diagnosis of hematological tumors, such as lymphomas, multiple myelomas, chronic lymphocytic leukemias, and myeloproliferative tumors, as well as nonhematological tumors, including tumors of the esophagus, breast, and central nervous system. Additionally, we explored the theranostic applications of CXCR4-targeting radioligands in tumors. Targeting CXCR4 using nuclear medicine shows promise as a method for tumor diagnosis, and further research is warranted to enhance its clinical applicability.