• Title/Summary/Keyword: Expanding roles

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Enigma of Small Peptides Ubiquitin and SUMO in Plants

  • Seo, Hak Soo
    • Korean Journal of Breeding Science
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    • v.42 no.4
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    • pp.339-343
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    • 2010
  • Post-translational covalent modifications by small molecules or peptides remodel target proteins. One such modification, made by ubiquitin or small ubiquitin-related modifier (SUMO), is a rapidly expanding field in cell signaling pathways. Ubiquitin attachment controls the turnover and degradation of target proteins while SUMO conjugation regulates their activity and function. Recent studies report many examples of cross-talk between ubiquitin and SUMO pathways, indicating that the boundary is no longer clear. Here, we review recent progress concerning how ubiquitin and SUMO participate in new regulatory roles in plant cell, and how ubiquitination and sumoylation control plant growth and development.

Limit-Zero Network: Trends of Hyper-Connected Photonics Technology for Limitless Network (한계 제로 네트워크: 한계 없는 네트워크를 위한 초연결 포토닉스 기술 동향)

  • Kim, K.;Park, H.;Chung, H.S.;Cho, S.H.;Lee, J.C.;Song, J.T.;Chang, S.H.;Lee, J.K.
    • Electronics and Telecommunications Trends
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    • v.34 no.1
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    • pp.49-60
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    • 2019
  • The prosperity of modern society is heavily depending on communication technology. Communication is now expanding its roles from personal convenience to social/industrial functioning. Photonics was first introduced to communication in longdistance transmission area since it provided wide bandwidth cost-effectively. However, nowadays, photonics is not only a harmonious collaborator with electronics, but has its own exclusive playgrounds in various parts of communication. Limit-zero network pursues a network that can provide abundant capacity and efficiency using very limited resources. Photonics is the most promising candidate to accomplish the goal. In this article, we review the current status and predict the future contributions of photonics to limit-zero network.

3'UTR Diversity: Expanding Repertoire of RNA Alterations in Human mRNAs

  • Dawon Hong;Sunjoo Jeong
    • Molecules and Cells
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    • v.46 no.1
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    • pp.48-56
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    • 2023
  • Genomic information stored in the DNA is transcribed to the mRNA and translated to proteins. The 3' untranslated regions (3'UTRs) of the mRNA serve pivotal roles in post-transcriptional gene expression, regulating mRNA stability, translation, and localization. Similar to DNA mutations producing aberrant proteins, RNA alterations expand the transcriptome landscape and change the cellular proteome. Recent global analyses reveal that many genes express various forms of altered RNAs, including 3'UTR length variants. Alternative polyadenylation and alternative splicing are involved in diversifying 3'UTRs, which could act as a hidden layer of eukaryotic gene expression control. In this review, we summarize the functions and regulations of 3'UTRs and elaborate on the generation and functional consequences of 3'UTR diversity. Given that dynamic 3'UTR length control contributes to phenotypic complexity, dysregulated 3'UTR diversity might be relevant to disease development, including cancers. Thus, 3'UTR diversity in cancer could open exciting new research areas and provide avenues for novel cancer theragnostics.

The Future of Work: Trends of Decentralized Autonomous Organizations (일의 미래: 탈중앙자율조직 DAO)

  • S.M. Choi
    • Electronics and Telecommunications Trends
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    • v.38 no.1
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    • pp.65-76
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    • 2023
  • Decentralized autonomous organizations (DAOs) is an effective and secure means to enable direct collaboration between people who want to achieve common goals in a digital environment, where believing each other without intermediaries from trusted third parties is difficult. DAO can flexibly implement most of the roles previously performed by existing organizations and finally aim for a new structure that functions independently without human intervention. Despite its technical and legal uncertainties and problems, DAO is rapidly expanding. This study examines trends such as the concept, use cases, participation methods, and deficiencies of DAO, which is called the future of work and helps to understand upcoming considerations.

Reflections on Application of VR Technology in Field of News Media

  • Chen Xi;Jeanhun Chung
    • International Journal of Internet, Broadcasting and Communication
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    • v.15 no.2
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    • pp.196-201
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    • 2023
  • In recent years, virtual reality (VR) technology has been widely used in many industrial fields, especially in the fields of medical treatment, games, film and television, to improve the interaction between medical teaching and practical treatment. On the gaming side, the production of virtual reality gaming screens and scenes became increasingly popular, greatly expanding the form of the visual experience. But VR is no longer confined to the health care, education and entertainment industries. During this time, the news media industry has also begun to integrate virtual reality into interviews and user interactions. This study aims to analyze the development of VR technology from the perspectives of immersive VR news experience, real reporting, and prospects, and analyze and think about the interactive participation of media users, the transformation of traditional media, and the upgrading of practitioners' roles.

Expanding roles of centrosome abnormalities in cancers

  • Soohyun Song;Surim Jung;Mijung Kwon
    • BMB Reports
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    • v.56 no.4
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    • pp.216-224
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    • 2023
  • Centrosome abnormalities are hallmarks of human cancers. Structural and numerical centrosome abnormalities correlate with tumor aggressiveness and poor prognosis, implicating that centrosome abnormalities could be a cause of tumorigenesis. Since Boveri made his pioneering recognition of the potential causal link between centrosome abnormalities and cancer more than a century ago, there has been significant progress in the field. Here, we review recent advances in the understanding of the causes and consequences of centrosome abnormalities and their connection to cancers. Centrosome abnormalities can drive the initiation and progression of cancers in multiple ways. For example, they can generate chromosome instability through abnormal mitosis, accelerating cancer genome evolution. Remarkably, it is becoming clear that the mechanisms by which centrosome abnormalities promote several steps of tumorigenesis are far beyond what Boveri had initially envisioned. We highlight various cancer-promoting mechanisms exerted by cells with centrosome abnormalities and how these cells possessing oncogenic potential can be monitored.

A Study on Logistical System and Operational Models of Franchise Store Retailing in China

  • Li, Dong-xin;Kang, Tae-won
    • The Korean Journal of Franchise Management
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    • v.3 no.1
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    • pp.130-143
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    • 2012
  • Franchise store retailing is taking on ever greater roles in business and commerce in China. The diverse product range, small-batch order, high frequency and time-specific requirements inherent in retail logistics make it the most complicated of all categories of logistics. In franchise store retailing, expanding business scales make trans-regional development a trend. Without a well-functioning logistic system, the standardized delivery of products would be held back, impacting trans-regional development strategy and operational costs. Therefore, the efficiency of franchise store retailing largely depends on logistical efficiency. The integrated and streamlined management of franchise stores depends in large measure on their logistical centers. As such, logistical centers constitute the key link and bears on core competitiveness in franchise store retailing. This thesis begins with an analysis of the current developments and four basic logistical models of franchise store retailing in China, proceeds to summarize developmental trends as well as focal issues and proposes an efficiency enhancing plan.

Effects of Organizational Use of KakaoTalk, a Mobile Instant Messaging (MIM) Service, on Employees' Attitudes toward Current Organization in Korea

  • Jaehee Cho
    • Asia pacific journal of information systems
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    • v.30 no.1
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    • pp.120-142
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    • 2020
  • Present-day organizations have become largely dependent on mobile instant messaging services (MIMs) for various organizational purposes. Focusing on the increasing use of MIMs in today's organizations, this study aims to explain how different aspects of KakaoTalk, the most dominant MIM in Korea, influence employees' attitudes toward their current employers, and how these attitudes impact the employees' intentions to stay at their present workplaces. Overall, with the exception of one factor (satisfaction with KakaoTalk use), all other factors (perceived quality of information exchanged through KakaoTalk, belongingness through KakaoTalk, and KakaoTalk overload) significantly influenced employee's attractiveness toward their current employers. Specifically, while KakaoTalk overload's effect on perceived organizational attractiveness was negative, two other factors were positively associated with it. Perceived organizational attractiveness also strongly influenced employees' intention to stay at their present workplaces. These findings contribute to expanding practical and theoretical understandings regarding the critical roles of MIMs in the efficient management of organizations in this hyperconnected society.

To Reveal or Conceal? Understanding the Notion of Privacy among Individuals

  • Sana Ansari;Sumeet Gupta
    • Asia pacific journal of information systems
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    • v.28 no.4
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    • pp.258-273
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    • 2018
  • What is individuals' privacy notion, and does it change with the social roles taken up by them? We explored these questions using a qualitative interpretive research approach. We found that individuals have mixed notion of privacy. Individuals view privacy either as a commodity or as a control. Further, we found that an individual's privacy notion is a function of their social role within the society and their privacy preferences. Our research points to the importance of expanding the notion of privacy to encompass a broader understanding of privacy preferences. We theorize our findings using social penetration theory and presents a privacy model which provides the logical framework for interpreting people's views on privacy.

Possibility of Expanding Citizen's Participation in Information Network Village (정보화마을사업 추진에서 주민참여의 확대가능성 모색 방안 연구)

  • Park, Youngmin;Seo, Jinwan
    • Informatization Policy
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    • v.22 no.2
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    • pp.35-56
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    • 2015
  • The study tried to explore the possibility of expanding citizen's participation in the case of Information Network Village(INVIL) with consideration of their different participation levels. As major players, central and local governments, INVIL itself, Central INVIL Committee and so forth have worked for the INVIL project and their importance levels of now and future were questioned and evaluated in the analysis. As a result, INVIL itself is regarded as the most important player for now and futrue as well. Central and local governments are also important to support the sustainability of this project. For future direction of INVIL project to be successfully sustainable, the specific roles of central and local governments were discussed and recommended to reduce explicit and potential conflicts among major players.