• Title/Summary/Keyword: Exhaled $CO_2$

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A Clinical Case Report on the Improvement of Respiratory Function of a Fascioscapulohumeral Muscular Dystrophy Patient after Korean Medical Treatment (안면견갑상완형 근이영양증 환자에 대한 한의학적 치료 이후 호흡기능 호전에 대한 임상 증례)

  • Lee, Sang Hyun;Jeong, Ju Yong;Cho, Myoung Rae
    • Journal of Acupuncture Research
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    • v.32 no.4
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    • pp.195-201
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    • 2015
  • Objectives : The purpose of this study is to report on the improvement of respiratory function of a fascioscapulohumeral muscular dystrophy patient after receiving Korean medical treatment. Methods : This study was carried out on a 60 year-old male patient who suffered from fascioscapulohumeral muscular dystrophy. While we carried out Korean medical treatment, we observed $EtCO_2$ (end-tidal carbon dioxide), Vte (exhaled tidal volume) and PIP (peak inspiratory pressure). Results : $EtCO_2$ count decreased from 34 mmHg to 24 mmHg during the treatment period, and PIP count became stable. Vte count also did not worsen in this study. Conclusions : Based on this study, we concluded that Korean medical treatment could be effective in treating fascioscapulohumeral muscular dystrophy patients with respiratory failure.

Bio-inspired Cr2O3 and Co3O4 Nanoparticles Loaded Electrospun WO3 Nanofiber Chemical Sensor for Early Diagnosis of Halitosis (고분산성 Cr2O3 및 Co3O4 전이금속 나노입자 촉매가 기능화된 다공성 WO3 나노섬유를 이용한 구취진단용 화학센서)

  • Jang, Ji-Soo;Kim, Sang-Joon;Choi, Seon-Jin;Koo, Won-Tae;Kim, Il-Doo
    • Journal of Sensor Science and Technology
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    • v.25 no.3
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    • pp.223-228
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    • 2016
  • In this work, we prepared porous WO3 nanofibers (NFs) functionalized by bio-inspired catalytic $Cr_2O_3$ and $Co_3O_4$ nanoparticles as highly sensitive and selective $H_2S$ gas sensing layers. Highly porous 3-dimensional (3D) NFs networks decorated by well-dispersed catalyst NPs exhibited superior $H_2S$ gas response ($R_{air}/R_{gas}$ = 46 at 5 ppm) in high humidity environment (95 %RH). In particular, the sensors showed outstanding $H_2S$ selectivity against other interfering analytes (such as acetone, toluene, CO, $H_2$, ethanol). Exhaled breath sensors using $Cr_2O_3$ and $Co_3O_4$ catalysts-loaded $WO_3$ NFs are highly promising for the accurate detection of halitosis.

Analysis of Natural Ventilation Effect of Seoul Metropolitan Subway by Monitoring Indoor $CO_2$ Concentrations (수도권 전동차 객실 $CO_2$농도관측을 통한 자연환기효과 해석)

  • Kwon, Soon-Bark;Cho, Young-Min;Park, Duck-Shin;Park, Eun-Young;Kim, Se-Young;Jung, Mi-Young
    • Proceedings of the KSR Conference
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    • 2007.11a
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    • pp.965-968
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    • 2007
  • Two major parameters, i.e. carbon dioxide ($CO_2$) and particulate matters smaller than $10{\mu}m\;(PM_{10})$, were selected as the index pollutants in managing indoor air quality. The former pollutant, $CO_2$, is the index that shows the ventilation status and is exhaled by passengers when they breathe in train or subway. It is generally known that high $CO_2$ concentration in the vehicle may be decreased by insufficient air-tightening vehicle bodies and the air is ventilated when vehicles stop at the station and doors open. However, there is no established proof or quantitatively identified data on how much the $CO_2$ concentration is reduced when ventilation is done while doors are opened. In this study, $CO_2$ concentrations were measured in 6 lines of Korail and one line of Seoul Metro subway linesand a theoretical approach was takento predict the changing trend of $CO_2$ concentrations during the operation of vehicle by using $CO_2$ dilution factor through natural ventilation. As a result, the change could be quantified and it was found that app. 35% of indoor $CO_2$ was removed through natural ventilation.

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A Comparative Study on the Effect of Smoking Cessation Education between CAI(Computer Assisted Instruction) and Lecture - Focused on Vocational High School Male Students - (CAI 개별 학습 프로그램을 적용한 금연 교육과 강의식 금연 교육의 효과 비교 - 실업계 남자 고등학생을 대상으로 -)

  • Lee Eun Suk;Kim Chung Nam
    • Journal of Korean Public Health Nursing
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    • v.19 no.1
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    • pp.74-94
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    • 2005
  • The purpose of this study was to compare the effect of education between CAI(Computer Assisted Instruction) and lectures for smoking cessation among male students who attended vocational high schools. Conducted from February 24th to April 26th, 2003, the study design was quasi-experimental with nonequivalent control group pretest-posttest design. The study subjects were 60 male students in K vocational high school in Daegu city, who were present smokers and had more than 7.0 ppm concentration level of carbon monoxide. Thirty students were randomly chosen as the experimental group which applied CAI education method for smoking cessation. The other 30 students served as the control group which received lecture education method of 40 minutes on four consecutive days. CAI education for smoking cessation was composed of ready-made individual learning contents, counseling by using cyber-communication, writing a letter to stop smoking, and writing a written agreement for smoking cessation. Lecture education for smoking cessation was composed of a ready-prepared lecture for the group, writing a letter to stop smoking, and writing a written agreement for smoking cessation. To measure smoking related knowledge, Jeong Ree Roh(1996)'s smoking related knowledge scale$(Cronbach's\;{\alpha}=0.84)$ was modified and used by the researcher. To measure smoking related attitude, Jeong Ree Roh(1996)'s smoking related attitude scale$(Cronbach's\;{\alpha}=0.91)$ was modified and used by the researcher. Smoking related knowledge scale's Cronbach's $\alpha$ was 0.83 in the pilot study and 0.93 in this study. Smoking related attitude scale's Cronbach's a was 0.80 in the pilot study and 0.98 in this study. To determine the smoking amount, the number of cigarettes smoked per day was checked. The concentration level of CO in the exhaled breath was measured (Micro CO Cat. No. MCO2, UK). Data was analyzed by $x^2-test$, t-test, repeated measures ANOVA. simple main effects, and time contrast test with SPSS/Win 11.0 program. The results of this study were as follows: 1. The first hypothesis. that 'Smoking-related knowledge score in the experimental group by using CAI education for smoking cessation will be higher than that in the control group by using lecture education for smoking cessation', was not supported. 2. The second hypothesis, that 'Smoking-related attitude in the experimental group by using CAI education for smoking cessation will be higher than that in the control group by using lecture education for smoking cessation'. was supported(F=6490.79. p=0.000). 3. The third hypothesis. that 'Smoking amount in the experimental group by using CAI education for smoking cessation will be less than that in the control group by using lecture education for smoking cessation'. was supported. 1) The third-1st sub-hypothesis. that 'The number of cigarettes smoked per day in the experimental group by using CAI education for smoking cessation will be less than that in the control group by using lecture education for smoking cessation'. was supported(F=134.19. p=0.000). 2) The third-2nd sub-hypothesis. that 'The concentration level of CO by ppm per one exhaled breath in the experimental group by using CAI education for smoking cessation will be lower than that in the control group by using lecture education for smoking cessation"' was supported(F=268.55. p=0.000). From the above results. CAI education can be an effective intervention to improve smoking-related knowledge and attitude. and to reduce the number of cigarettes smoked per day and the concentration level of CO by ppm per one exhaled breath. Lecture education can be effective to improve smoking-related knowledge. In the future, when CAI education and lecture education for smoking cessation are applied on the school nursing field. the students can gain a comprehensive understanding of smoking cessation, changes in smoking-related knowledge. smoking-related attitude and reducing smoking amount. Furthermore, CAI education for smoking cessation could be developed as an individual self initiative program and could give a guideline to apply CAI education for smoking cessation in other field.

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Studies on the Indirect Measuring Method of the Maximum Voluntary Ventilation (최대환기능의 간접측정법에 관한 연구)

  • Park, Hae-Kun;Kim, Kwang-Jin;Sung, Hae-Sook;Jeon, Byung-Sook
    • The Korean Journal of Physiology
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    • v.11 no.2
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    • pp.45-50
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    • 1977
  • The maximum voluntary ventilation (MVV) is one of the most widely used pulmonary function test, but its measuring method was very difficult and unreliable. However, it is need to get more easy and simple measuring method of MVV. Therefore, this study was attempted to get more easy and simple measuring method of MVV by means of the forced expiratory volume $(FEV_{T})$. The young and healthy 1,000 Korean students(592 male and 408 female) were cheesed for this purpose and whose ages were from 8 to 20 years. A spirometer (9L, Collins Co.) was used for the MVV and FEV, and they were measured 3 times at standing position, and the highest value was used. In the measurements, the subjects for MVV were asked for the breath as fast and deeply as possible for 12 seconds, and for FEV were asked for the rapid and forceful exhalation after a maximal inhalation (forced expiratory curve). In the FEV measurements toward the end of the expiration, the subjects were exhaused to continue the effort until no further gas was expired. During these measurements, the investigator stood by the subject to give a constant encouragement. FEV were calculated in the volume exhaled during the one-half $(FEV_{0{\cdot}5,}\;ml)$, the first second $(FEV_{1{\cdot}0,}\;ml)$ and the percentage of the total vital capacity exhaled during the one-half second $(FEV_{0{\cdot}5,}\;%)$. The results are summarized as follows: 1) The values of MVV were increased linearly with ages until 20 in both sexes. The values of male at the age of 20 was $168.2{\pm}2.5L/min$, and female at the age of 17 was $112.3{\pm}3.0L/min$, respectively. 2) The values of FEV (ml) were increased linearly with ages until 20 in both sexes. The values of $FEV_{0{\cdot}5}$ were $2,797{\pm}65.7ml$ in the male of 20 years and were $2,088{\pm}54.6ml$ in the female of 17 years, and of $FEV_{1{\cdot}0$ were $4,119{\pm}68.2ml$ in the male of 20 years and were $2,897{\pm}65.9ml$ in the female of 17 years, respectively. 3) The correlation coefficients between MVV and $FEV_{0{\cdot}5}\;or\;FEV_{1{\cdot}0$ (ml) were 0.82 or 0.85 in the male, and 0.77 or 0.79 in the female, respectively. 4) The prediction formulae for MVV to be derived from above results were: For male: MVV (L/min) =7.19+$0.05{\times}FEV_{0\cdot5}(ml)$, MVV (L/min)=11.25+$0.04{\times}FEV_{1\cdot0}(ml)$ For female: MVV (L/min)=16.03+$0.05{\times}FEV_{0\cdot5}(ml)$, MVV (L/min)=9.47+$0.03{\times}FEV_{1\cdot0}(ml)$.

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An Analysis of the Characteristics and Preferences Related to a Smoking Cessation Program among Smoking College Students (흡연대학생의 제 특성과 금연프로그램 선호도 분석)

  • Kim, Eun Kyung;Song, Mi Ryeong
    • Journal of Korean Biological Nursing Science
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    • v.15 no.4
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    • pp.184-192
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    • 2013
  • Purpose: The purpose of this study was to analyze the characteristics and preferences related to a smoking cessation program among college students to help college students quit smoking. Methods: This study used a cross-sectional survey to analyze collected data from 324 college students who had a positive reaction to a urine nicotine test. Collected data were analyzed with descriptive statistics using SPSS 20.0. Results: The smoking amount per day of the participants was 4.1 pieces, and the average smoking period was 5.2 years. The mean of the CO level in exhaled air of the participants was 8.95 ppm. Their urge to smoke increased after a meal or while drinking alcohol. Most students wanted to quit smoking. Half of them were in a preparation phase to quit. Students wanted their willingness and determination to be reinforced (48%), and wanted to learn about specific smoking cessation methods (33%) through a smoking cessation program. Most of the students (60%) wanted an online program to help them quit smoking. Conclusion: To help students quit smoking, a online program that strengthens their determination to quit, and which contains specific methods to help them is needed.

Effects of Panax ginseng on Alcohol Detoxification (인삼의 알콜해독 효과)

  • Lee F.C.;Ko J.H.;Park J.K.;Lee J.S.
    • Proceedings of the Ginseng society Conference
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    • 1988.08a
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    • pp.25-27
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    • 1988
  • To assess the effect of Panax ginseng on the detoxification of ethanol. we examined its effect on blood ethanol clearance in both man and experimental animals and on the rate of ethanol oxidation to carbon dioxide in experimental animals. Fourteen healthy male volunteers were subject to studies. The blood alcohol level in the test group receiving ginseng extract (3g/kg b.w.) along with alcohol (70g/65kg b.w.) was about $35\%$ lower than their control levels at 40 min after ethanol intake. When the blood alcohol level was compared on individual bases. blood alcohol concentrations in 10 subjects ranged from 32 to $51\%$ lower than their control values. The remaining 4 subjects appeared to have a high tolerance level. In experimental animals. the blood alcohol clearance was also much faster in test animals receiving ginseng along with ethanol. The rate of ethanol elimination was determined by the amount of $^{14}CO_2$ in exhaled air following the administration of [$^{14}C$] ethanol. During the first 7 1/4 hr (Phase I) after the ethanol administration. the $CO_2$ output was greater in test animals receving ginseng along with ethanol. whereas from beyond 7 1/4 hr to the near end (Phase II). the $CO_2$ output in control animals was over twice that in test animals. The present studies clearly demonstrate that ginseng promotes the overall metabolism of ethanol. resulting in an enhanced blood alcohol clearance and alcohol elimination.

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Effect of n-6/n-3 fatty acid ratio on hepatic glycerolipid partitioning in second generation rats (n-6/n-3 지방산 비율이 차세대 랫드의 지질대사 분할에 미치는 영향)

  • Park, Byung-Sung
    • Journal of the Korean Applied Science and Technology
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    • v.34 no.4
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    • pp.839-850
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    • 2017
  • The objective of this study was to investigate the effect of diets with different omega-6 (n-6) and omega-3 (n-3) fatty acid ratios (0, 1.2: 1, 8: 1, 19: 1) on mechanisms of partitioning of in vivo hepatic glycerolipid metabolism in next generation rats. Biomonitoring techniques were used in rats (jugular vein cannula were attached). The range of $^{14}CO_2$ exhaled by glycerolipid metabolism was 7.05-20.17% in the group having diet with n-6/n-3 ratio less than 8:1. It was the lowest in the control group. Total glycerolipid was the highest in the control group. For groups with different n-6/n-3 ratio, it had the following order: 19:1>8:1>1.2:1. Secreted triglyceride was decreased by 36.35%, 20.93%, and 13.72% in 1.2:1,8:1, and 19:1 groups, respectively, compared to that in the control group. The ratio of phospholipid to total glycerolipid was 1.38, 1.29, and 1.17 times higher in 1.2:1, 8:1, and 19:1 groups, respectively, compared to that in the control group. The ratio of $^{14}CO_2$ to total glycerolipid was 1.61, 1.52, and 1.29 times higher in 1.2:1, 8:1, and 19:1 groups, respectively, compared to that in the control group.

Smoking Relapse and Related Factors Within One Year Among Successes of the Smoking Cessation Clinics of Public Health Centers (보건소 금연클리닉 금연성공자의 1년내 재흡연과 관련요인)

  • Kim, Mi-Jag;Jeong, Ihn-Sook
    • Journal of Preventive Medicine and Public Health
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    • v.44 no.2
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    • pp.84-92
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    • 2011
  • Objectives: This study aimed to investigate smoking relapse and the related factors within 1 year after discharge from the smoking cessation clinics (SCCs) of public health centers (PHCs). Methods: Data were collected with a structured questionnaire from 395 people who success fully stopped smoking at 4 SCCs in Busan between May and June 2009, and this data were analyzed by Kaplan-Meier survival curves and the Cox proportional hazard model. Results: The rate of smoking relapse within 1 year after discharge from SCCs was 39.2% and this decreased rapidly over 6 months after discharge. The factors related to smoking relapse within 1 year after discharge from SCCs were being female (HR, 2.11; 95% CI, 1.17 to 3.82), a trial of smoking cessation with any assistants (HR, 1.95; 95% CI, 1.19 to 3.19), more than 7 ppm of exhaled CO2 on the SCCs' registration (HR, 1.81; 95% CI, 1.24 to 2.64), use of pharmacotherapy after discharge from SCCs (HR, 2.00; 95% CI, 1.36 to 2.93), alcohol drinking more than once a week after discharge from SCCs (HR, 3.32; 95% CI, 2.15 to 6.78), and a perceived barrier (HR, 1.21; 95% CI, 1.14 to 1.30) after discharge from the SCCs. Conclusions: According to the results, at least 6 months follow-up after discharge from SCCs of public health centers is recommended to reduce the rate smoking relapse. It is also recommended to strengthen the education on how to overcome barriers such as drinking in the course of smoking cessation clinics.

The Relationship between Indoor Air Pollutants and Pulmonary Function in Asthmatic Children with Mold Sensitization (곰팡이에 감작된 소아 천식 환자 가정내 환경유해물질 농도와 폐기능의 상관관계)

  • Yoon, Wonsuck;Lim, Jaehoon;Park, Sang Hyun;Lee, Mingyu;Yoo, Young
    • Journal of Environmental Health Sciences
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    • v.46 no.6
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    • pp.685-693
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    • 2020
  • Objectives: Recent data indicate that sensitization to mold contributes to the severity and persistence of asthma. The aim of this study was to investigate relationships between indoor mold concentrations and pulmonary function parameters in asthmatic children with mold sensitization. Methods: Asthmatic subjects who had a positive result in skin-prick testing to more than one mold allergen, such as Alternaria, Aspergillus, or Penicillium, were enrolled. Their pulmonary function and methacholine challenge test results were collected. Measurements of blood eosinophil, serum IgE, and fractional exhaled nitric oxide (FeNO) were taken. Indoor levels of VOC, CO2, PM10 and PM2.5 in each subject's house were measured. We counted mold and bacteria colonies from the subjects' house air samples. Results: The mean levels of FEV1, FVC, FEV1/FVC, and FEF25-75 were 82.8±19.7, 87.3±17.9, 85.8±8.3, and 82.3±28.9%, respectively. The mean FeNO level was 19.8±11.2 ppb and the geometric mean (range of one SD) of methacholine PC20 was 3.99 mg/mL (0.67-23.74 mg/mL). The average indoor air pollutant levels were below the recommended levels set by the Ministry of Environment for multiplex buildings. Indoor mold levels showed a significant inverse correlation with methacholine PC20, but not with the baseline pulmonary function parameters. Conclusion: Indoor mold concentrations are a risk factor for increased bronchial hyperresponsiveness among asthmatic children with mold sensitization. Targeted environmental intervention should be considered for selected asthmatic children with mold sensitization for avoiding severe airway hyperresponsiveness.