• Journal of the Korea Institute of Military Science and Technology
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• v.15 no.2
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• pp.121-129
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• 2012

In this study, in terms of the exercise vehicles of the weapon systems having negative buoyancy, the analysis on the operation concepts was performed and the new methods of floating to surface were proposed. In case of having negative buoyancy, the additional methods for recovering the exercise vehicle have to be considered. As parts of recovering the exercise vehicle, for floating to surface the new methods of weight discharge, weight separation and sea water discharge were proposed. The conceptual design about sea water discharge method was performed. It was confirmed that those methods could be applied to the design of the exercise vehicle having negative buoyancy.

• Korean Journal of Medicinal Crop Science
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• v.26 no.1
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• pp.72-81
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• 2018

Background: Polysaccharides are the most important functional constituent in Astragalus membranaceus. The purpose of the present study was to evaluate the effect of polysaccharides isolated from the aboveground parts of A. membranaceus (AMA) and polysaccharides isolated from the roots of A. membranaceus (AMR) immune function by modulated cytotoxic T cell and Th1- and Th2-related cytokines kinetics. Methods and Results: Sprague-Dawley rats were randomly divided into exhaustive exercise case groups and non-exercise case, AMA and AMR samples were administered orally for 30 days (500 mg/kg/day and 10 mg/kg/day, respectively) and were compared to those rats in the groups fed commercial sports drink (SPD) and vehicle. Both exhaustive exercise groups and non-exercise groups had a lower ratio of $CD4^+$ and $CD8^+$ cells in the spleens of the rat fed AMA and AMR compared to those in the rats fed SPD and vehicle group. These results suggested that AMA and AMR promote an increase in the proportion of cytotoxic T cells. The IL-4-producing T lymphocytes decreased significantly in the AMR (10 mg/kg/day) group compared to SPD and vehicle, whereas the AMA group increased the IL-4 concentration more than the SPD and vehicle in exhaustive exercise group. However, the populations of IFN-${\gamma}$-producing T lymphocytes of AMR and AMA increased. AMA decreased the concentration of IFN-${\gamma}$ to inhibit the Th1 response and thereby increased the concentration of IL-4 to induce a Th2 response that was related to humoral immunity in the non-exercise group. Conclusions: These results showed that, in addition to Th1/Th2 regulation, AMR and AMA played an important immuno-modulatory role after exhaustive exercise-induced Th1/Th2 lymphocyte imbalance, which might be correlated with cytokine producing immunoregulatory cells.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.12
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• pp.5878-5904
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• 2017

This paper proposes a novel intelligent wheelchair vehicle system that enables upper limb exercises, lower limb standing exercises and rehabilitation training in a daily life. The proposed system, which can be used to prevent at least the degeneration of body movements and further atrophy of musculoskeletal system functions, considers the characteristics and mobility of the old and the disabled. Its main purpose is to help the old and the disabled perform their daily activities as much as they can, minimizing the extent of secondary disabilities. In other words, the system will provide the old and the disabled with regular and quantitative rehabilitation exercises and diagnosis using the wheelchair-based upper/lower limb rehabilitation vehicle system and then verify their effectiveness. The system comprises an electric wheelchair, a biometric module to identify individual characteristics, and an upper/lower limb rehabilitation vehicle. In this paper the design and configuration of the developed vehicle is described, and its operation method is presented. Moreover, to verify the tracking performance of the proposed system, dangerous situations according to biosignal changes occurring during the rehabilitation exercise of a non-disabled examinee are analyzed and the performance of the upper/lower limb rehabilitation exercise function depending on muscle strength is evaluated through a neural network algorithm.

• Korean Journal of Pharmacognosy
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• v.44 no.1
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• pp.83-90
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• 2013

The aim of this study was to evaluate the effect of hot water extract of peduncle obtained from Hovenia dulcis Thunb (HD) which is commercially developed for the protective effect on the alcoholic hepatotoxicity, on the endurance capacity for weight loaded forced swimming mice. The swimming times to exhaustion in mice fed 100 and 200 mg/kg HD for 2 weeks were prolonged 3.6 and 3.7 fold, and for 4 weeks 1.9 and 2.7 fold compared with each vehicle control ($42.8{\pm}20.5$ min and $67.7{\pm}47.8$ min, for 2 and 4 weeks), respectively. Blood biochemical parameters for ALT, AST, creatinine and BUN were not significantly different between from HD fed or control mice. Although HD fed mice swam over 2 fold longer time than vehicle control mice at 4 weeks, blood biomarkers of physical fatigue such as glucose, triglyceride and free fatty acid, lactate were not significant different and even tended to ameliorate. Hepatic lipid peroxidation and SOD activity did not significantly change in HD fed- and vehicle control exhausted swimming mice at 2 or 4 weeks. However, catalase activity in HD-fed mice was significantly increased in a dose-dependent manner compared with vehicle control mice. The present study indicates that HD improved physical fatigue and exercise performance in mice. Therefore, it has a potential for the pharmacological effect of anti-fatigue.

• Korean Journal of Pharmacognosy
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• v.47 no.3
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• pp.258-263
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• 2016

In this study, we tested anti-fatigue effect of Kyung-Ok-Ko (KOK). We examined the exercise performance effects of KOK (600 mg/kg) at 2nd, 3rd and 4th week. The exercise performance of KOK treated group was significantly improved than that of vehicle control (VC) group on grip strength (2nd week), exhausted time of treadmill (3rd week) and exhausted time of weight loaded swimming (4th week). We also investigated the effects of KOK on the change of fatigue parameters in blood, skeletal muscle and liver after swimming exercise. KOK significantly reduced lactate level and enhanced glucose level in blood. Equally KOK significantly increased glycogen in skeletal muscle. However, the glycogen level of KOK in the liver was not significantly increased compared to VC group. These results show that supplementation of KOK may improve the anti-fatigue activity and exercise capacity.

• Journal of Life Science
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• v.25 no.11
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• pp.1214-1222
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• 2015

The purpose of this study was to determine the effect of Pueraria lobate-root based combination supplementation containing Rehmannia glutinosa and exercise on histone modification in ovariectomized rat hindlimb skeletal muscle. Sixty rats were fed with high fat diet and randomly assigned into the following groups for 8 weeks: 1)HSV; High fat+Sedentary+Vehicle, 2)HSP; High fat+Sedentary+PR, 3)HSH; High fat+Sedentary+Estradiol, 4)HEV; High fat+Ex+Vehicle, 5)HEP; High fat+Ex+PR, 6)HEH; High fat+Ex+Estradiol. Exercise consisted of low intensity treadmill exercise(1-4th wk:15 m/min for 30 min, 5-8th wk: 18 m/min for 40 min, 5 times/week). The result of this study showed that exercise and Pueraria and Rehmannia glutinosa intake suppressed weight gain. Furthermore, exercise and Pueraria and Rehmannia glutinosa intake increased muscle mass. This study observed H3K9 acetylation and demethylation in plantaris muscle in exercised group, but no difference in soleus muscle. To test whether the decrease in HDAC4, HDAC5 and G9a mRNA levels after exercise and Pueraria/Rehmannia glutinosa intake, HDAC4, HDAC5 and G9a mRNA levels were determined by real-time PCR. Only exercise induced HDAC5 and G9a mRNA reduction in plantaris muscle, but not in soleus muscle. In conclusion, these data demonstrates that exercise and Pueraria/Rehmannia glutinosa intake effect on body compositions. These changes are regulated by epigenetic modifications, such as histone acetylation and methylation. Future studies should focus on gene-specific epigenetics and other epigenetic mechanism for Pueraria/Rehmannia glutinosa intake.

• Structural Engineering and Mechanics
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• v.18 no.5
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• pp.609-626
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• 2004

The Land Transport Authority of Singapore has a continuing program of highway bridge upgrading, to refurbish and strengthen bridges to allow for increasing vehicle traffic and increasing axle loads. One subject of this program has been a short span bridge taking a busy highway across a coastal inlet near a major port facility. Experiment-based structural assessments of the bridge were conducted before and after upgrading works including strengthening. Each assessment exercise comprised two separate components; a strain and acceleration monitoring exercise lasting approximately one month, and a full-scale dynamic test carried out in a single day. This paper reports the application of extreme value statistics to estimate bridge live loads using strain measurements.

• Journal of the Korea Furniture Society
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• v.23 no.4
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• pp.467-478
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• 2012

Interurban railway is expanded by transportation that population can be centralism and cope efficiently in traffic jam by augmentation of vehicles in the city. Railroad chair departs in space of an existent simple rest and products that can raise human body standard and size by powerful engineering vicinity, quality of the material, psychological satisfaction etc. of users are developed steadily. Specially, study of space that can use various materials efficiently with bodily size government official because various of man and woman old and the young etc.. are using in occasion of the train is urgently required. Specially, railroad chair is a product that material and standard, structure, human body engineering, a finish etc. is studied variously. In the case of advanced nation, in case of design a chair operating time of railroad, is placed as all standards orderly and harmonious because is considered exercise dynamics etc.. and designs. The other side, in the case of our country, study expert of chair is short real and is depending on technological data of overseas railway vehicle. Chair for railroad must consider removal of short-range, long distance. That have to be consider to a lot of uncomfortable such as psychological satisfaction of user because the domestic Motor Companies are defining in fair development study and many researchers but the railroad chair company are not accumulated professional manpower and technological know-how. Railway vehicle can recognize that overseas visitors as well as native is important element as space that space is exposed internationally by product that Public personality which used cultural value is strong. Therefore, wish to plan valid spec relationship presentation of various design and specification, function etc.. and contribute to railroad chair development design process lists and analyzes van instances of railway vehicle chair of inside and outside of the country through this study.

• Proceedings of the KSR Conference
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• 2007.11a
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• pp.816-823
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• 2007

As the South Korean rolling stock industry is developing designs for full compliance with the European Standards, it is fitting to take a look at these two core standards. The paper presents an overview of the load cases and structural requirements developed in Europe for the design of safe and compatible rolling stock vehicles. These load cases and structural requirements have been compiled into two standards namely EN12663 and EN15227. Standard EN12663 was developed as a reference design requirements standard. The work was mandated and sponsored by the European Committee for Standardization and Standard issuing National Institutions. EN12663 specifies a series of proof and fatigue load cases for European rolling stock regulations compliant vehicle designs. As EN12663 does not address the crashworthiness issue, a dedicated crashworthiness standard, EN15227, was therefore developed in a similar manner through industry wide consultations managed by a Trans-European working group of experienced engineers and specialists. In both standards, the vehicle and/or trains are grouped into categories reflecting the vehicle types and/or their indented operational function. EN15227, developed to complement EN12663, addresses the "passive" crashworthiness capability of the vehicles and trains. EN15227 specifies reference crash scenarios similar to those found in the Technical Specification for Interoperability (TSI) of high speed trains operating in Europe. The overview also touches on a general comparison with the corresponding British Group Standard (GM/RT2100) and also the UIC leaflet based load cases. The exercise is extended to pertinent design load cases specified by the Federal Railroad Administration (FRA) in the US.

• Smart Structures and Systems
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• v.15 no.3
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• pp.665-682
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• 2015

Structural identification or St-Id is 'the parametric correlation of structural response characteristics predicted by a mathematical model with analogous characteristics derived from experimental measurements'. This paper describes a St-Id exercise on Humber Bridge that adopted a novel two-stage approach to first calibrate and then validate a mathematical model. This model was then used to predict effects of wind and temperature loads on global static deformation that would be practically impossible to observe. The first stage of the process was an ambient vibration survey in 2008 that used operational modal analysis to estimate a set of modes classified as vertical, torsional or lateral. In the more recent second stage a finite element model (FEM) was developed with an appropriate level of refinement to provide a corresponding set of modal properties. A series of manual adjustments to modal parameters such as cable tension and bearing stiffness resulted in a FEM that produced excellent correspondence for vertical and torsional modes, along with correspondence for the lower frequency lateral modes. In the third stage traffic, wind and temperature data along with deformation measurements from a sparse structural health monitoring system installed in 2011 were compared with equivalent predictions from the partially validated FEM. The match of static response between FEM and SHM data proved good enough for the FEM to be used to predict the un-measurable global deformed shape of the bridge due to vehicle and temperature effects but the FEM had limited capability to reproduce static effects of wind. In addition the FEM was used to show internal forces due to a heavy vehicle to to estimate the worst-case bearing movements under extreme combinations of wind, traffic and temperature loads. The paper shows that in this case, but with limitations, such a two-stage FEM calibration/validation process can be an effective tool for performance prognosis.