• IMMUNE NETWORK
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• 제5권2호
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• pp.117-123
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• 2005

The immune response to any stimulus is complex, requiring coordinated action by several types of cells in a tightly regulated sequence. Thus, a physical stress such as exercise may act at any number of points in the complex sequence of events collectively termed the immune response. Although exercise causes many propound changes in parameters of immune function, the nature and magnitude of such changes rely on several factors including the immune parameters of interest; type, intensity, and duration of exercise; fitness level or exercise history of the subject; environmental factors such as ambient temperature and humidity. Although regular moderate exercise appears to be important factor for increasing immunity, Athletes are susceptible to illness, in particular upper respiratory track infection, during periods of intense training and after competition. In addition, in elite athletes, frequent illness is associated with overtraining syndrome, a neuroendocrine disorder resulting from excessive training. Through this paper, we want to investigate the effects of exercise on the immunosuppression such as exercise induced lymphopenia, asthma, anaphylaxis, URT (upper respiratory track), and TB (tuberculosis) infection. and also, we want to suggest a direct mechanism, protection and therapy of exercise induced immunosuppression.

• 음성과학
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• 제10권2호
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• pp.169-189
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• 2003

Trained singers, one group of professional voice users, have much more interest on the voice than common people, and on its management, too. They train for singing beautiful songs, and, at the same time, try for efficient voice production. The present study was performed with three tenors and three baritones, undergraduate students majored in classical singing, to investigate the degree of improvement of their voice production efficiency through vocal function exercise, by measuring the three dependent variables, maximum phonation time, speed quotient of glottal contact, and the number of semi tones. For the baseline establishment, dependent variables were measured 3$\sim$6 times for two weeks. Then, the subjects exercised vocal function exercise for seven weeks, and after the termination of training, evaluation was performed four times for two weeks, to find the maintenance of the training effect. Vocal function exercise is composed of four successive steps: warm-up, stretching exercise, contracting exercise, power exercise. As results, all of six subjects showed improvement in the aspect of maximum phonation time, speed quotient if glottal contact, and the number of semitones.

• The Korean Journal of Physiology and Pharmacology
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• 제19권3호
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• pp.191-196
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• 2015

Attenuated functional exercise capacity in elderly and diseased populations is a common problem, and stems primarily from physical inactivity. Decreased function and exercise capacity can be restored by maintaining muscular strength and mass, which are key factors in an independent and healthy life. Resistance exercise has been used to prevent muscle loss and improve muscular strength and mass. However, the intensities necessary for traditional resistance training to increase muscular strength and mass may be contraindicated for some at risk populations, such as diseased populations and the elderly. Therefore, an alternative exercise modality is required. Recently, blood flow restriction (BFR) with low intensity resistance exercise (LIRE) has been used for such special populations to improve their function and exercise capacity. Although BFR+LIRE has been intensively studied for a decade, a comprehensive review detailing the effects of BFR+LIRE on both skeletal muscle and vascular function is not available. Therefore, the purpose of this review is to discuss previous studies documenting the effects of BFR+LIRE on hormonal and transcriptional factors in muscle hypertrophy and vascular function, including changes in hemodynamics, and endothelial function.

• Physical Therapy Rehabilitation Science
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• 제4권1호
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• pp.17-21
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• 2015

Objective: In this study, we aimed to test the hypothesis that aerobic exercise might exert its cardio-protective effect by preventing oxidative stress and improving cardiac function in rat models with doxorubicin-induced cardiomyopathy. Design: Randomized controlled trial. Methods: We randomly divided experimental rats into four groups: the normal group was used as a non-cardiomyopathy normal control (n=10); the control group included non-aerobic exercise after doxorubicin-induced cardiomyopathy (n=10); the experimental group I included aerobic exercise (3 m/min) after doxorubicin-induced cardiomyopathy (n=10); and experimental group II included aerobic exercise (8 m/min) after doxorubicin-induced cardiomyopathy. Rats in the treadmill training groups underwent treadmill training, which began at 2 weeks after the first intraperitoneal injection. At the end of the exercise period, we determined the heart weight change for each rat. Changes in the levels of oxidative stress enzymes (superoxide dismutase [SOD], thiobarbituric acid-reactive substances [TBARS], and catalase) in the cardiac tissue of rats from all four groups were examined at the end of the experiment. Results: Significant cardiac myocyte injury and increase in myocardial TBARS concomitant with a reduction in myocardial SOD and catalase were observed following cardiomyopathy (p<0.05). Significant cardiac tissue and increase in myocardial TBARS along with reduction in myocardial SOD and catalase were observed following cardiomyopathy (p<0.05). Oxidative parameters were significantly improved in the aerobic exercise groups compared with the control group. Conclusions: These findings indicate that aerobic exercise effectively prevents oxidative stress in rat models with cardiomyopathy.

• 정형스포츠물리치료학회지
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• 제14권2호
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• pp.99-107
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• 2018

Purpose: This study investigated scoliosis muscle activity after the trunk side shift exercise. Methods: Fifty-eight subjects (control group=30, scoliosis group=28) participated in this study. The patients with idiopathic scoliosis were randomly divided into two groups: the side shift exercise (SSE) group and the trunk stabilization exercise (TSE) group. The SSE group performed SSE with chair training for eight weeks. A one-way ANOVA test was carried out to compare the results within the idiopathic scoliosis patient group prior to and after different exercise methods. Result: The muscle activity differences of the TPS, LPS, and latissimus dorsi muscles significantly decreased in all idiopathic scoliosis exercises groups after training. According to the exercise method, the TPS differed between the control group (CG) and TSE group and between the SSC and TSE groups. The LPS and latissimus dorsi muscles showed differences between the CG and TSE groups. Conclusions: This study found that the side shift exercise effectively improve spine muscles. The side shift exercise was performed using chairs that were designed for this study. Thus, this method is easily accessible for busy students who are exposed to scoliosis or spinal disorders that are caused by a pattern of inactivity.

• 운동영양학회지
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• 제23권1호
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• pp.21-27
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• 2019

[Purpose] In the present pilot study, we aimed to investigate the effects of the Silverrobics exercise program, which is similar to aerobic dance, on the factors related to glucose metabolism and liver enzymes. [Methods] Eight elderly women with obesity and impaired fasting glucose participated in the Silverrobics exercise program (60 minutes per session for five times a week for 8 weeks). The program was conducted at 50-60% of the heart rate reserve at 1 to 2 weeks and at 60-80% of the heart rate reserve at 3 to 8 weeks. To verify the effect of this 8-week exercise program on glucose metabolism and liver enzymes, blood analysis at pre- and post-training was performed. [Results] After the Silverrobics exercise program, there were significant decreases in the glucose (p<0.05), glycated hemoglobin A1c (p<0.05), 1,5-anhydroglucitol (p<0.05), and insulin levels (p<0.01) and homeostatic model assessment of insulin resistance score (p<0.05). However, there were no significant effects on the liver enzymes, except for alkaline phosphatase. The alkaline phosphatase level increased after the Silverrobics exercise program (p<0.05). [Conclusion] Although the Silverrobics exercise program had no beneficial effects on the liver enzymes, it may play an important role in preventing liver diseases considering the effects on glucose metabolism.

• 한국응용과학기술학회지
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• 제38권3호
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• pp.750-761
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• 2021

이 연구는 노화된 흰쥐를 대상으로 규칙적인 저항성 운동에 유산소 운동을 병행하는 훈련을 실시하여 골격근에서 나타나는 혈관신생 관련 단백질 발현의 반응을 관찰하기 위해 수행되었다. 연구의 목적을 위해 자연적으로 노화된 SD계열 흰쥐(20-24개월령, N=18)를 사용하여 통제(CON, n=6), 저항성 운동(RE, n=6), 저항성+유산소 운동(RE+AE, n=6) 집단으로 구분하였다. 저항성 운동 집단은 실험동물용 사다리를 이용하여 매회 3세트×4회의 운동을 실시하였고 저항성 운동+유산소 운동 집단은 매회 2세트×3회의 사다리 오르기와 추가적인 30분간의 트레드밀 달리기를 수행하였다. 총 8주간의 운동 훈련 종료 후 가자미 근과 장지신근을 적출하여 분석에 사용하였다. 골격근에서 혈관신생 관련 단백질들(HIF-1α, VEGF, FLK-1, Ang-1, Ang-2)의 발현 수준을 분석하기 위해 western blot을 실시하였다. 연구결과, 저항성+유산소 운동 집단에서 가자미근(type I 근육)의 HIF-1α, VEGF, FLK-1, Ang-1, Ang-2 단백질 발현이 통제집단에 비해 높았으며 저항성 운동만 수행할 경우 HIF-1α, VEGF, Ang-1, Ang-2 단백질 발현이 통제집단에 비해 높았다. 또한 가자미근에서 저항성+유산소 운동훈련 집단의 Ang-2 to Ang-1 ratio가 저항성 운동 집단에 비해 높아 운동훈련 유형별 차이를 보였다. 한편, 장지신근(type II 근육)에서 HIF-1α는 저항성 운동 훈련에 의해서만 증가된 반면 VEGF와 FLK-1 단백질 발현은 두 훈련 유형 모두에서 증가되었고 운동 훈련 유형별 차이는 관찰되지 않았다. 또한 장지신근의 angiopoieitin 단백질들의 발현은 운동 훈련에 의한 차이가 없었다. 그러므로 노화에서 규칙적인 운동 훈련은 운동 유형에 관계없이 골격근 혈관신생 반응을 유도하며, 특히 저항성 운동에 유산소 운동의 병행은 type I 근조직 유형에서 혈관신생에 대한 추가적인 긍정적 효과를 가질 수 있다.

• 대한통합의학회지
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• 제4권2호
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• pp.1-11
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• 2016

Purpose : The purpose of this study was to identify whether virtual reality-based exercise could improve on balance, gait and fall efficacy in patients with Parkinson's disease. Methods : Ten patients with Parkinson's disease were randomly divided into either an experimental or control group. The experimental subjects performed vertual reality-based exercise, whereas the control subjects performed conventional physical therapy for 4 weeks. The balance, gait and fall efficacy of all subjects were assessed by using the Measurement Training and Documentation (MTD) balance system, force platform system, Korean version of Berg Balance scale (K-BBS), 6 Minute Walk Test (6MWT), and Korean version of Fall efficacy scale (K-FES) at pre training and post training. Wilcoxon signed rank test was used to analyze change before and after intervention in intra-group. Mann Whitney U test was used to analyze changes of all variables in inter-groups. Results : Subjects in the experimental group showed significant improvements in difference of weight distribution, K-BBS scores, antero-posterior and medio-lateral sway length, ground reaction force (GRF), 6MWT, and step length following training. The changes of difference of weight distribution, K-BBS scores, AP Sway Length, GRF, 6MWT, step length and K-FES scores in the experimental group were significantly more than them of the control group. Conclusion : The result of this study suggest that virtual reality-based exercise training is an intervention to improve on balance, gait, and falls efficacy in patients with Parkinson's disease.

• Physical Therapy Rehabilitation Science
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• 제10권4호
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• pp.421-429
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• 2021

Objective: The purpose of this study was to examine the effect of personalized complex aerobic training programs using wearable device on cardiovascular and respiratory functions in community based female elderly. Design: One group pre-post intervention study. Methods: Twenty-one older female participants lived in 'D' city were included. The personalized complex aerobic training program using wearable devices was applied to all participants for 4 weeks, 3 times a week, 30 minutes for per session. The participants' blood pressure, heart rate, oxygen saturation, respiration rate, submaximal exercise stress test, pulmonary function test and respiratory muscle strength test were evaluated before and after the complex training program. Results: After intervention, resting diastolic blood pressure, resting systolic blood pressure and the systolic blood pressure after submaximal exercise stress test were significantly decreased over time (p<0.05), and the submaximal exercise stress test duration were significantly increased over time (p<0.05). The maximal inspiratory pressure (MIP) was significantly increased compare to before the intervention (p<0.05). Conclusions: This study showed that personalized complex training program using wearable device can provide personalized exercise intensity according to cardiopulmonary function that give feedback, and these interventions have a significant effect on improving the cardiovascular and respiratory system functions of the female elderly in the community dwelling.

• 대한통합의학회지
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• 제9권3호
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• pp.203-211
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• 2021

Purpose : It was to compare changes in respiratory function (pulmonary function, inspiratory function) after four weeks of inspiratory muscle strengthening training (diaphragmatic breathing with upper arm exercise, Power-Breathe breathing) for 36 healthy people. Methods : Subjects were randomly assigned to diaphragmatic breathing with upper arm exercise (Group I) and Power-breathe breathing (Group II) was conducted by the protocol for four weeks five times per week. As the main measurement method for comparison between groups For pulmonary function, Forced Vital Capacity (FVC) and Forced Expiratory Volume at One second (FEV1) were used, and for inspiratory function, Maximum Inspiratory Capacity (MIC), Maximum Inspiratory Pressure (MIP), and Maximum Inspiratory Flow Rate (MIFR) were used. Results : In changes in pulmonary function between groups, FVC and FEV₁ showed no significant difference, and in inspiratory function changes, MIC showed no significant difference, but in MIP and MIFR, Group B significantly improved over Group A. Conclusion : The progressive resistance training using the Power-breath device applied to the inspiratory muscle did not show a significant difference in the increase in the amount of air in the lungs and chest cage compared to the diaphragmatic breathing training accompanied by the upper arm exercise. However, by increasing the air inflow rate and pressure, it showed a more excellent effect on improving respiratory function.