• Journal of Animal Science and Technology
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• 제55권2호
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• pp.87-93
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• 2013

We identified four new bovine tri-nucleotide microsatellite loci and analyzed their sequence structures and genetic parameters in 105 randomly selected Korean cattle (Hanwoo). Allele numbers of the loci B17S0808, B15S6253, B8S7996, and B17S4998 were 10, 11, 12, and 29, respectively. These alleles contained a simple or compound repeat sequences with some variations. Allele distributions of all these loci were in Hardy-Weinberg equilibrium (P > 0.05). Observed heterozygosity and expected heterozygosity ranged from 0.54 (B15S6253) to 0.92 (B17S4998) and from 0.599 (B15S6253) to 0.968 (B17S4998), respectively, and two measures of heterozygosity at each locus were highly correlated. Polymorphism information content (PIC) for these 4 loci ranged from 0.551 (B15S6253) to 0.932 (B17S4998), which means that all these loci are highly informative (PIC > 0.5). Other genetic parameters, power of discrimination (PD) and probability of exclusion (PE) ranged from 0.783 (B15S6253) to 0.984 (B17S4998) and from 0.210 (B15S6253) to 0.782 (B17S4998), respectively. Their combined PD and PE values were 0.9999968 and 0.98005176, respectively. Capillary electrophoresis revealed that average peak height ratio for a stutter was 13.89% at B17S0808, 26.67% at B15S6253, 9.09% at B8S7996, and 43.75% at B17S4998. Although the degree of genetic variability of the locus B15S6253 was relatively low among these four microsatellite markers, their favorable parameters and low peak height ratios for stutters indicate that these four new tri-nucleotide microsatellite loci could be useful multiplex PCR markers for the forensic and population genetic studies in cattle including Korean native breed.

• 한국물환경학회지
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• 제23권6호
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• pp.843-849
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• 2007

Monitoring of NOM characteristics is important for improving removal efficiency of natural organic matter (NOM) in water treatment processes. In this study, several NOM characteristics, which include specific UV absorbance (SUVA), total carbonate content, molecular weight distribution, and fluorescence properties, were measured using samples collected from a pilot-scale water treatment plant consisting of coagulation/flocculation (C/F), filtration, ozonation and granular activated carbon (GAC) processes. The highest removal of NOM was observed in C/F and filtration processes as demonstrated by the reduction of dissolved organic carbon (DOC) by 25% and 21%, respectively. Despite nearly no change in DOC, however, the lowest SUVA value and the highest total carbohydrate content were observed in the sample from ozonation process. This indicates that non-degradable aromatic compounds become depleted and biodegradable organic compounds are enriched during the process. Comparison of synchronous fluorescence spectra of the samples showed that ozoation process increased protein-like fluorescence while it decreased fulvic-like and terrestrial humic-like fluorescence. Consistently, a slight peak of protein-like fluorescence was observed in the sample from ozonation process. The greatest change in molecular weight distributions of the samples was observed in C/F process. Comparison of size exclusion chromatogram of the samples revealed that NOM fractions with the molecular weight greater than 2000 Da were reduced by over 90% after C/F process. SUVA values and total carbohydrate content of the samples were well correlated with a ratio of protein-like fluorescence and terrestrial humic-like fluorescence intensities with the correlation coefficients of 0.99 and 0.91, respectively. This suggests that synchronous fluorescence properties of NOM could be used as useful tolls for monitoring changes of some NOM characteristics during water treatment processes.

• 정보관리연구
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• 제23권1호
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• pp.39-62
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• 1992

본(本) 연구(硏究)는 실제의 데이터 분석(分析)을 통하여 60여개의 조사(助詞)와 출현빈도는 높지만 검색(檢率)에 불필요한 320여개의 불용어(不用語)를 선정하여 좌우절단을 적용한 네 가지 유형으로 분류하고 조사(助詞)와 불용어 테이블을 구성하는 방법(方法)을 제시한다. 한글문헌에서 단어(單語)가 추출되면 조사의 효율적인 절단이 이러우지고, 한자어(漢字語)일 경우 한글로 변환되며, 2단계로 불용어제거(不用語除去) 과정을 거쳐 키워드를 선정하는 시스템을 개발한다. 여기서 추출된 키워드는 정보전문가(情報專門家)에 의해 추출된 색인어(索引語)와는 92.2%의 일치율을 보였다. 그리고 $4{\sim}6$글자로 구성된 복합어(複合語)의 경우 본(本) 연구(硏究)에서 제시한 분리방법에 의해 약 2배의 새로운 단어(單語)를 추가할 수 있었으며 그 중 58.8%가 키워드로 적합했다.

• Journal of Gastric Cancer
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• 제15권4호
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• pp.256-261
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• 2015

Purpose: Gastric cancer is the third leading cause of cancer-related mortality, with the incidence and mortality being higher in men than in women. Various studies have shown that eating carrots may play a major role in the prevention of gastric cancer. We conducted a meta-analysis to determine the relationship between carrot consumption and gastric cancer. Materials and Methods: We searched multiple databases including PubMed, Cochrane Library, Scopus, ScienceDirect, and Persian databases like Scientific Information Database (SID) and IranMedx. The following search terms were used: stomach or gastric, neoplasm or cancer, carcinoma or tumor, and carrot. Statistical analyses were performed using Comprehensive Meta Analysis/2.0 software. Results: We retrieved 81 articles by searching the databases. After considering the inclusion and exclusion criteria, 5 articles were included in this study. The odds ratio (OR) obtained by fixed effects model showed that a 26% reduction in the risk of gastric cancer has been associated with the consumption of carrots) OR=0.74; 95% confidence interval=0.68~0.81; P<0.0001). According to funnel graph, the results showed that the possibility of a publication bias does not exist in this study. Conclusions: The findings of this study showed an inverse relationship between the consumption of carrots and the risk of gastric cancer.

• 디지털융복합연구
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• 제18권3호
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• pp.235-245
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• 2020

본 연구는 다문화가정 아동·청소년의 심리적 지원을 위한 음악 중재 연구의 현황과 특성을 알아보기 위한 문헌고찰 연구이다. 선정 기준과 배제 기준에 따라 2009년부터 2018년까지 발표된 학위논문 13편과 학술지 논문 6편, 총 19편을 고찰한 결과, 첫째, 일반적 특성에서 연구 설계는 비무선 배치 실험연구와 단일 집단 사전사후 실험연구가 높은 비중을 차지하였고, 13세 이하 아동 대상 연구가 가장 많았다. 둘째, 음악 중재 특성에서 목표는 자아정체감, 자아존중감, 자아개념 등 자기 관련 요인이 많았고, 중재활동은 노래, 악기, 창작을 혼합한 그룹 형태가 대부분이었다. 본 연구는 다문화가정 아동청소년의 심리지원을 위한 음악 중재 프로그램의 개발 시 기초자료로 활용될 수 있으며, 향후 이들의 특성을 고려한 음악 중재가 더욱 활발히 수행될 것을 제안한다는 점에서 의의를 갖는다.

• 기술혁신학회지
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• 제15권1호
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• pp.105-128
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• 2012

본 논문에서는 특허맵 분석 데이터 구축 과정에서 필요한 효율적인 노이즈 제거방법과 신뢰도가 향상된 기술수준 평가를 제안한다. 과거 수작업으로만 진행하였던 노이즈 제거 과정을 논리 연산자 AND를 활용하여 엑셀 VBA(Visual Basic Application)에서 프로그램화 하여 효율적으로 제거하여 유효 데이터를 획득할 수 있게 된다. 신뢰도가 향상된 특허의 기술수준 평가를 위하여 평균 청구항 수, 특허 패밀리 사이즈(PFS: Patent Family Size), 특허당 인용도 지수(CPP: Cites per Patent), 삼극특허, 규격화 특허경쟁력 지수(stdPCPI: Standardization Patent Diversification Index), haF-index(Hirsch a Family index)등을 사용하게 된다. 제안된 효율적인 노이즈 제거 작업을 적용한 결과는 획득된 특허 데이터의 노이즈 비율이 10% 미만으로 나타나서 데이터의 신뢰도가 높음이 확인되었다. 제안된 기술수준 평가 지수를 적용한 결과는 공통적으로 확인할 수 있는 정보에 의해 기술수준 평가를 산출함으로써 신뢰도가 향상된 균형적 기술수준 평가가 가능함을 확인할 수 있었다.

• Toxicological Research
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• 제33권4호
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• pp.291-297
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• 2017

This study was performed to investigate the dose-response relationship between average daily cadmium dose (ADCD) from rice and the occurrence of urinary cadmium (U-Cd) in individuals eating that rice. This was a retrospective cohort designed to compare populations from two areas with different levels of cadmium contamination. Five-hundred and sixty-seven participants aged 18 years or older were interviewed to estimate their rice intake, and were assessed for U-Cd. The sources of consumed rice were sampled for cadmium measurement, from which the ADCD was estimated. Binary logistic regression was used to examine the association between ADCD and U-Cd (cut-off point at $2{\mu}g/g$ creatinine), and a correlation between them was established. The lowest estimate was $ADCD=0.5{\mu}g/kg\;bw/day$ [odds ratio (OR) = 1.71; with a 95% confidence interval (CI) 1.02-2.87]. For comparison, the relationship in the contaminated area is expressed by $ADCD=0.7{\mu}g/kg\;bw/day$, OR = 1.84; [95 % CI, 1.06-3.19], while no relationship was found in the non-contaminated area, meaning that the highest level at which this relationship does not exist is $ADCD=0.6{\mu}g/kg\;bw/day$ [95% CI, 0.99-2.95]. Rice, as a main staple food, is the most likely source of dietary cadmium. Abstaining from or limiting rice consumption, therefore, will increase the likelihood of maintaining U-Cd within the normal range. As the recommended maximum ADCD is not to exceed $0.6{\mu}g/kg\;bw/day$, the consumption of rice grown in cadmium-contaminated areas should not be more than 246.8 g/day. However, the exclusion of many edible plants grown in the contaminated area from the analysis might result in an estimated ADCD that does not reflect the true level of cadmium exposure among local people.

• 한국잠사곤충학회지
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• 제28권1호
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• pp.37-42
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• 1986

누에의 5령 60시간째 합성효약 홀몬(JHA)을 체중 1g당 1$\mu\textrm{g}$, 10$\mu\textrm{g}$을 경피투여한 후 체액 중 단백질 및 아미노산의 변동을 조사하였던 바 그 결과는 다음과 같다. 1. 5령유충기간은 대조구보다 JHA-1구가 1일, JHA-10구가 4일 연장되었다. 2. 견종 및 견층종은 합성효약 홀몬 투여구가 대조구보다 무거웠고, 견층비율은 JHA-10구가 낮았다. 3. 체액단백질의 농도는 합성효약홀몬투여구가 대조구에 비해 현저하게 증가하였다. 4. 체액 중 전 아미노산양은 JHA-10구가 대조구에 비해 약 2배 정도 많았으며, 특히 glycine와 arginine의 증가 정도는 현저하다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제22권1호
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• pp.1-10
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• 2022

Background: Inferior alveolar nerve block (IANB) is known to have a lower success rate for anesthesia in patients with irreversible pulpitis. This calls for supplementary techniques to effectively anesthetize such patients. This systematic review aimed to evaluate the published literature for determining the success rate of anesthesia induction using post-IANB intraligamentary (IL) injection in the mandibular teeth of patients with symptomatic irreversible pulpitis. The review question was, "What is the success rate of IL injection in the mandibular teeth of patients with irreversible pulpitis as a supplementary technique for endodontic treatment?" Methods: A thorough search of electronic databases and manual searches were performed. The protocol of the review was framed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist and was registered in the International Prospective Register of Ongoing Systematic Reviews (PROSPERO) with a proper criterion for inclusion and exclusion of studies. The included studies were analyzed using the Cochrane Collaboration "Risk of Bias" tool. A meta-analysis that included a comparison of primary nerve block and supplemental IL injection was performed. The success rate was evaluated using the combined risk ratio (RR) with a random risk model. A funnel plot was created to measure publication bias. Results: After all analyses, four studies were included. In the forest plot representation, RRs were 3.56 (95% CI: 2.86, 4.44), which were in favor of the supplemental IL injections. Statistical heterogeneity was found to be 0%. These values suggest that supplemental IL injections provide better success rates for anesthesia. Conclusion: According to the pooled qualitative and quantitative analyses, supplemental IL injections increased anesthetic efficacy.

• Korean Circulation Journal
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• 제53권8호
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• pp.550-562
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• 2023

Background and Objectives: To identify the factors associated with adverse outcomes following surgery for functional insufficiency of the mitral valve (MV) or tricuspid valve (TV) associated with atrial fibrillation (AF). Methods: We evaluated 100 patients (age, 66.5±10.0 years; 47 males) who consecutively underwent surgery for functional insufficiency of the MV or TV associated with AF between January 2000 and December 2020 at our center. The primary outcome was a composite endpoint of all-cause death, valve reoperation, congestive heart failure (CHF) requiring rehospitalization, and stroke. Results: During follow-up (532 patients-years [PYs]), adverse events included death in 16 (3.0%/yr), MV reoperation in 1 (0.2%/yr), CHF in 14 (2.6%/yr), and stroke in 5 (0.9%/yr) patients, demonstrating a 5-year rate of freedom from the primary endpoint of 69.5%. The rate of postoperative AF was high even in those who underwent AF ablation (n=92), with cumulative rates of 48.1% at 1 year and 60.2% at 5 years. In multivariable analyses, the primary outcome was significantly associated with age (adjusted hazard ratio [aHR], 1.06; 95% confidence interval [CI], 1.02-1.10; p=0.005), chronic kidney disease (aHR, 7.76; 95% CI, 2.28-26.38; p=0.001), left atrial appendage exclusion (aHR, 0.35; 95% CI, 0.16-1.78; p=0.010), and postoperative AF as a time-varying covariate (aHR, 3.33; 95% CI, 1.50-7.40; p=0.003). Conclusion: Among patients undergoing surgery for functional atrioventricular insufficiency associated with AF, a significant proportion showed recurrence of AF over time after concomitant AF ablation, which was significantly associated with poor clinical outcomes.