Anesthetic efficacy of supplemental intraligamentary injection in human mandibular teeth with irreversible pulpitis: a systematic review and meta-analysis |
Gupta, Alpa
(Department of Conservative Dentistry and Endodontics, Manav Racha Dental College)
Wadhwa, Jitesh (Department of Orthodontics and Dentofacial Orthopedics, Manav Racha Dental College) Aggarwal, Vivek (Department of Conservative Dentistry and Endodontics, Faculty of Dentistry) Mehta, Namrata (Department of Conservative Dentistry and Endodontics, Manav Racha Dental College) Abraham, Dax (Department of Conservative Dentistry and Endodontics, Manav Racha Dental College) Aneja, Kritika (Department of Conservative Dentistry and Endodontics, Manav Racha Dental College) Singh, Arundeep (Department of Conservative Dentistry and Endodontics, Manav Racha Dental College) |
1 | Aggarwal V, Singla M, Miglani S, Kohli S. Comparative evaluation of mental incisal nerve block, inferior alveolar nerve block, and their combination on the anesthetic success rate in symptomatic mandibular premolars: a randomized double-blind clinical trial. J Endod 2016; 42: 843-5. DOI |
2 | Stenholm E, Bongenhielm U, Ahlquist M, Fried K. VRl- and VRL-l-like immunoreactivity in normal and injured trigeminal dental primary sensory neurons of the rat. Acta Odontol Scand 2002; 60: 72-9. DOI |
3 | Aggarwal V, Singla M, Rizvi A, Miglani S. Comparative evaluation of local infiltration of articaine, articaine plus ketorolac and dexamethasone on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis. J Endod 2011; 37: 445-9. DOI |
4 | Pereira LA, Groppo FC, Bergamaschi Cde C, Meechan JG, Ramacciato JC, Motta RH, et al. Articaine (4%) with epinephrine (1:100,000 or 1:200,000) in intraosseous injections in symptomatic irreversible pulpitis of mandibular molars: anesthetic efficacy and cardiovascular effects. Oral Surg Oral Med Oral Pathol Oral Radiol 2013; 116: e85-91. DOI |
5 | Lin S, Wigler R, Huber R, Kaufman AY. Anaesthetic efficacy of intraligamentary injection techniques on mandibular molars diagnosed with asymptomatic irreversible pulpitis: a retrospective study. Aust Endod J 2017; 43: 34-7. DOI |
6 | Jing Q, Wan K, Wang XJ, Ma L. Effectiveness and safety of computer-controlled periodontal ligament injection system in endodontic access to the mandibular posterior teeth. Chin Med Sci J 2014; 29: 23-7. DOI |
7 | Fan S, Chen WL, Pan CB, Huang ZQ, Xian MQ, Yang ZH, et al. Anesthetic efficacy of inferior alveolar nerve block plus buccal infiltration or periodontal ligament injections with articaine in patients with irreversible pulpitis in the mandibular first molar. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 108: e89-93. DOI |
8 | Zarei M, Ghoddusi J, Sharifi E, Forghani M, Afkhami F, Marouzi P. Comparison of the anaesthetic efficacy of and heart rate changes after periodontal ligament or intraosseous X-tip injection in mandibular molars: a randomised controlled clinical trial. Int Endod J 2012; 45: 921-6. DOI |
9 | Aggarwal V, Singla M, Miglani S, Kohli S, Sharma V, Bhasin SS. Does the volume of supplemental intraligamentary injections affect the anaesthetic success rate after a failed primary inferior alveolar nerve block? A randomized-double blind clinical trial. Int Endod J 2018; 51: 5-11. DOI |
10 | Aggarwal V, Singla M, Miglani S, Kohli S. Efficacy of Articaine versus Lidocaine administered as supplementary injection after a failed inferior alveolar nerve block: A randomised double blind study. J Endod 2019; 45: 1-5. DOI |
11 | Lapidus D, Goldberg J, Hobbs EH, Ram S, Clark GT, Enciso R. Effect of premedication to provide analgesia as a supplement to inferior alveolar nerve block in patients with irreversible pulpitis. J Am Dent Assoc 2016; 147: 427-37. DOI |
12 | Reisman D, Reader A, Nist R, Beck M, Weaver J. Anesthetic efficacy of the supplemental intraosseous injection of 3% mepivacaine in irreversible pulpitis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997; 84: 676-82. DOI |
13 | Fowler S, Drum M, Reader A, Beck M. Anesthetic success of an inferior alveolar nerve block and supplemental articaine buccal infiltration for molars and premolars in patients with symptomatic irreversible pulpitis. J Endod 2016; 42: 390-2. DOI |
14 | Meechan JG. Supplementary routes to local anaesthesia. Int Endod J 2002; 35: 885-96. DOI |
15 | Nusstein J, Claffey E, Reader A, Beck M, Weaver J. Anesthetic effectiveness of the supplemental intraligamentary injection, administered with a computer-controlled local anesthetic delivery system, in patients with irreversible pulpitis. J Endod 2005; 31: 354-8. DOI |
16 | Shapiro MR, McDonald NJ, Gardner RJ, Peters MC, Botero TM. Efficacy of articaine versus lidocaine in supplemental infiltration for mandibular first versus second molars with irreversible pulpitis: a prospective, randomized, double-blind clinical trial. J Endod 2018; 44: 523-8. DOI |
17 | Haas DA, Harper DG, Saso MA, Young ER. Comparison of articaine and prilocaine anesthesia by infiltration in maxillary and mandibular arches. Anaesth Prog 1990; 37: 230-7. |
18 | Malamed SF. The periodontal ligament (PDL) injection: an alternative to inferior alveolar nerve block. Oral Surg Oral Med Oral Pathol 1982; 53: 117-21. DOI |
19 | Kanaa MD, Whitworth JM, Meechan JG. A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teeth. J Endod 2012; 38: 421-5. DOI |
20 | Hargreaves KM, Keiser K. Local anesthetic failure in endodontics: mechanisms and management. Endod Topics 2002; 1: 26-39. DOI |
21 | Shabazfar N, Daublander M, Al-Nawas B, Kammerer PW. Periodontal intraligament injection as alternative to inferior alveolar nerve block-meta-analysis of the literature from 1979 to 2012. Clin Oral Investig 2014; 18: 351-8. DOI |
22 | Moore PA, Cuddy MA, Cooke MR, Sokolowski CJ. Periodontal ligament and intraosseous anesthetic injection techniques: alternatives to mandibular nerve blocks. J Am Dent Assoc 2011; 142(Suppl 3): 13S-8S. DOI |
23 | Parirokh M, Sadr S, Nakhaee N, Abbott PV, Askarifard S. Efficacy of supplementary buccal infiltrations and intraligamentary injections to inferior alveolar nerve blocks in mandibular first molars with asymptomatic irreversible pulpitis: a randomized controlled trial. Int Endod J 2014; 47: 926-33. DOI |
24 | Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 2009: 151: 264-9. DOI |
25 | Aggarwal V, Singla M, Saatchi M, Hasija M. Anaesthetic efficacy of 2% lidocaine with different concentrations of epinephrine (1:80,000and 1:200,000) in intraligamentary injection after a failed primary inferior alveolar nerve block:a randomized double-blind study. Acta Odontol Scand 2020; 78: 275-80. DOI |
26 | Heft MW, Parker SR. An experimental basis for revising the graphic rating scale for pain. Pain 1984; 19: 153-61. DOI |
27 | Aggarwal V, Jain A, Kabi D. Anesthetic efficacy of supplemental buccal and lingual infiltrations of articaine and lidocaine following an inferior alveolar nerve block in patients with irreversible pulpitis. J Endod 2009; 35: 925-9. DOI |
28 | Higgins JPT, Green S, eds. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available at: www.cochrane-handbook.org. Accessed August 11, 2015. |
29 | Zanjir M, Lighvan NL, Yarascavitch C, Beyene J, Shah PS, Azarpazhooh A. Efficacy and Safety of Pulpal Anesthesia strategies during endodontic treatment of permanent mandibular molars with symptomatic irreversible pulpitis: a systematic review and network meta-analysis. J Endod 2019; 45: 1435-64. DOI |
30 | Cohen HP, Cha BY, Spangberg LSW. Endodontic anesthesia in mandibular molars: a clinical study. J Endod 1993; 19: 370-3. DOI |
31 | Nusstein J, Reader A, Nist R, Beck M, Meyers WJ. Anesthetic efficacy of the supplemental intraosseous injection of 2% lidocaine with 1:100,000 epinephrine in irreversible pulpitis. J Endod 1998; 24: 487-91. DOI |
32 | White JJ, Reader A, Beck M, Meyers WJ. The periodontal ligament injection: a comparison of the efficacy in human maxillary and mandibular teeth. J Endod 1988; 14: 508-14. DOI |
33 | Shahi S, Mokhtari H, Rahimi S, Yavari HR, Narimani S, Abdolrahimi M, et al. Effect of premedication with ibuprofen and dexamethasone on success rate of inferior alveolar nerve block for teeth with asymptomatic irreversible pulpitis: a randomized clinical trial. J Endod 2013; 39: 160-2. DOI |
34 | Chaudhary P, Martenson ME, Baumann TK. Vanilloid receptor expression and capsaicin excitation of rat dental primary afferent neurons. J Dent Res 2001;80: 1518-23. DOI |
35 | Harbour R, Miller J. A new system for grading recommendations in evidence based guidelines. BMJ 2001; 323: 334-6. DOI |
36 | Mohajeri L, Salehi F, Mehrvarzfar P, Arfaee H, Bohluli B, Hamedy R. Anesthetic efficacy of meperidine in teeth with symptomatic irreversible pulpitis. Anesth Prog 2015; 62: 14-9. DOI |
![]() |