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A Study on Subchronic Inhalation Toxicity of 2-Methylpentane (2-Methylpentane 아만성 흡입독성 연구)

  • Chung, Yong Hyun;Lim, Cheol Hong;Han, Jeong Hee
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.24 no.2
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    • pp.169-181
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    • 2014
  • Objectives: The purpose of this study was to obtain information regarding classification and health hazards that may result from a 13-week inhalation exposure to 2-methylpentane by Sprague-Dawley rats. Materials: The testing method was conducted in accordance with OECD guidelines for the testing of chemicals No. 413. The rats were divided into four groups(ten male and ten female rats in each group) and exposed to 0 ppm, 290 ppm, 1,160 ppm, 4,640 ppm 2-Methylpentane in each exposure chamber for six hours per day, five days per week, for 13 weeks. Results: No death or particular clinical presentation including weight change and change of feed rate was observed. The relationships between dose, gender and response were also not significantly changed in urinalysis, hematologic examination, or biochemical examination of blood(except for total cholesterol being up, total protein being up, and chloride ion being down in males), and blood coagulation time. For the relative weight measurement of organs, in the male group the weight change of both kidney and liver were increased in proportion to dose. In histopathological examination, nephropathy in the kidney(cystic change of renal tubules, regenerative tubule, inflammatory cell infiltration and necrosis in the interstitial tissue) was increased in a dose-dependent manner in the male group(290 ppm, 1,160 ppm, 4,640 ppm). However, other organs were not affected by the test substance. Conclusions: 2-methylpentane was estimated as a chemical causing nephropathy in the male group. NOAEL(No Observable Adverse Effect Level) in the female group is more than 4,640 ppm, while inthe male group it is less than 290 ppm.

A Study on Activities of Diagnostic X-ray Examination(II) (X선진단(X線診斷) 부문(部門)에 있어서 업무량(業務量)에 관(關)한 조사연구(調査硏究)(II))

  • Kyong, Kwang-Hyon;Huh, Joon
    • Journal of radiological science and technology
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    • v.1 no.1
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    • pp.44-54
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    • 1978
  • This study was carried out with statistical materials during the last two years of period from Jan. 1975 to Dec. 1976 which presented at radiologic department of 5 hospitals in Seoul City. The primary purpose of this study was to obtained more detailed informations related to the activities of radiologic technologists in diagnostic X-Ray examinations part and to provide some basic materials for managements in activities of then and manpower managements of their organization and practice. From the results of this study, the following conclusions were obtained [1] During two year from the January of 1975 to the December of 1976, total number of case in X-ray examinations were 464,830 case and 22,029 case in 1975 and 24,461 in 1976. And ratio of icreased in X-Ray examinations by year was 11.09 per cent. [2] Regarding the examined portion of X-Ray examination, a great propotion was chest examination as 56.88 per cent. [3] An average, the required time per case in X-Ray exam. was 9.28 minutes and make used of 1.94 sheets of X-Ray film per case in radiography. [4] An average, ratio of increased in X-Ray film by year was 12.71 per cent and ratio of failed film in it was 2.23 per cent. [5] The frequency rate of film size showed the highest distribution of $8"{\times}10"$(28.17%) and the highest distribution of X-Ray film by month was July(8.93%). [6] An average, the amount of activities per a diagnostic X-Ray equipment was 34.92 case and make used of 67.81 sheets of X-Ray film in a day. [7] The mean number of case in X-Ray examinations by radiologic technologists was 29.29 cases and make used of 56.87 sheets of X-Ray film in a day. Also, the average number of case was reading by radiologists was 32.42 case and 62.97 sheets of X-Ray film in a day.

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The Relationship between Temporomandibular Disorders(TMD) and Occlusion (측두하악장애와 교합요인의 관계)

  • Kim, Seong-Taek;Lee, You-Sik
    • Journal of Dental Rehabilitation and Applied Science
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    • v.21 no.1
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    • pp.43-57
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    • 2005
  • Temporomandibular disorders have been defined as a collective term embracing a number of clinical problems that involve the temporomandibular joint, the masticatory nuscles, and associated structures. There have been many different contributing factors of TMDs which were traumatic, occlusal, pathophysiological and psychosocial. Among there factors, the effect of occlusion on TMDs have been a controversy for a long time. The purpose of this study was to investigate the effect of occlusal factors and oral habits on TMDs. In this study, 140 subjects with signs and symptoms of TMDs and diagnosed of TMD in the Orofacial Pain clinic of Yonsei University Dental Hospital though March to July 2004 were selected for the TMDs group and 50 subjects without any signs and symptoms of TMDs as the control group. The subjects were evaluated clinically in TMDs' Occlusal and Prosthodontic Restoration examinations. TMDs' examination was composed of the TMJ pain, sound, locking, temporal or masseter muscle palpation, mandibular movement, oral habits and headache. Occlusal examination was made of overjet, overbite, lost teeth number, nonfunctional interference, midline shift, then pattern of lateral movement and attrition. prosthodontic restoration examination had the existence of restoration, placement, then number of crown or bridge and Satisfiable index which estimated the quality of occlusal state of prosthodontic restorations. Following results were obtained : 1. The prevalence of TMDs was higher in their 20s & 30s, female of the TMD patients group. 2. The clenching frequency in the TMDs group(40.71%) was higher than those in the control group(18.00%), and there was a significant statistical difference(p<0.05). 3. The frequency of Nonfunctional interference in the TMDs group(10.00%) was higher than those in then Control group(2.00%), and there was a significant statistical difference(p<0.05). The result of this study indicated TMDs prevalence was higher in their 20s, 30s, female group of TMDs patients similar to the previous studies. Clenching and nonfunctional interference were estimated as the contributing factors of TMDs.

Exploration of Barriers to Breast-Self Examination among Urban Women in Shah Alam, Malaysia: A Cross Sectional Study

  • Al-Dubai, Sami Abdo Radman;Ganasegeran, Kurubaran;Alabsi, Aied M.;Manaf, Mohd Rizal Abdul;Ijaz, Sharea;Kassim, Saba
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1627-1632
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    • 2012
  • Background: Breast cancer is the most common cancer among women in Malaysia. Barriers for practicing breast self examination (BSE) await exploration. Objective: To assess the practice of BSE and its correlated factors and particularly barriers amongst urban women in Malaysia. Methods: This cross-sectional study was conducted with 222 Malaysian women using a self-administered questionnaire. Results: The mean (SD) age was 28.5 (${\pm}9.2$) years, 59.0% were university graduates. Of the total, 81.1% were aware of breast cancer and 55% practiced BSE. Amongst 45% of respondents who did not practice BSE, 79.8% did not know how to do it, 60.6% feared being diagnosed with breast cancer, 59.6% were worried about detecting breast cancer, 22% reported that they should not touch their bodies, 44% and 28% reported BSE is embarrassing or unpleasant, 29% time consuming, 22% thought they would never have breast cancer or it is ineffective and finally 20% perceived BSE as unimportant. Logistic regression modeling showed that respondents aged ${\geq}45$ years, being Malay, married and having a high education level were more likely to practice BSE (p<0.05). Conclusion: In this study sample, a significant proportion of respondents was aware of breast cancer but did not practice BSE. Knowledge, psychological, cultural, perception and environmental factors were identified as barriers. BSE practice was associated significantly with socio-demographic factors and socioeconomic status.

CLINICAL SUBTYPING AND TREATMENT STRATEGY OF COLLEGE ENTERANCE EXAMINATION STRESS SYNDROME (입시병의 아형과 대처방안)

  • Lee, Young-Sik;Ku, Young-Jin;Lee, Kil-Hong
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.2 no.1
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    • pp.43-48
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    • 1991
  • The College entrance examination stress syndrome is a kind of anxiety disorder. The underlying cause of this disorder is not a test anxiety itself. One's hidden inner and familial conflicts are more likely attributed to this disorder. Patient's the most common complaints are various psychosomatic symptoms but in severe cases underlying psychopathology may be activated and progress to major psychosis. In a broad sense adolescent's delinguent behavior, drug abuse, school drop-out and sucide are closely related to this syndrome. In clinical management of these patients, considering the special situation of impending examination, the therapist must access to central conflict theme in a short time without severe resistance. The authors classified this syndrome into 5 clinical subtypes ; 'the anxious group', 'the exhaustion group', 'the despair group', 'the emptyness group' and 'the boredome group'. Typical case of each subtype and it's management methods were presented briefly.

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Investigation of variations in energy, macronutrients and sodium intake based on the places meals are provided - Using the Korea National Health and Nutrition Examination Survey (KNHANES, 1998-2009) -

  • Kwon, Yong-Seok;Park, Young-Hee;Choe, Jeong-Sook;Yang, Yoon-Kyoung
    • Nutrition Research and Practice
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    • v.8 no.1
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    • pp.81-93
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    • 2014
  • This study was conducted to investigate nutrient consumption by Korean adults in various places. To accomplish this, we used the 1998-2009 Korea National Health and Nutrition Examination Survey (KNHANES). Subjects of this investigation were over 19 years and the study included 37,160 people. The meals were categorized as breakfast, lunch, dinner, and snacks consumed at home, or while eating-out. Investigation of the rate of consumption at serving places based on daily meals and years showed that eating-out generally increased with time. The consumption of meals prepared at home was higher than that of meals consumed anyplace else in 1998, 2001, 2005, and 2007-2009. However, the rate of consumption of home meals decreased from 1998 to 2007-2009, while the rate of eating-out increased during this period. Annual nutrient intake according to serving places with respect to meals, energy, fat, and sodium were significantly lower in home meals than those consumed elsewhere in 2007-2009 relative to 1998. The sodium intake and energy distribution ratio of fat in meals consumed while eating-out increased significantly from 1998 to 2007-2009. The energy, fat and sodium intake and energy contribution ratio of fat consumed in meals at institutions was significantly higher in 2007-2009 than in 1998. Based on these results, additional research is required to develop guidelines for dietary life improvement at each serving place and to address education and policies for balanced nutrition intake.

The relationship between periodontal disease prevalence and occupation among Korean adults aged 19-39 according to the 6th Korea National Health and Nutrition Survey (제 6기(2013-2015) 국민건강영양조사 자료를 이용한 19-39세 한국 성인의 취업과 치주질환 관계)

  • Kim, Han-Na
    • Journal of Korean society of Dental Hygiene
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    • v.18 no.5
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    • pp.631-641
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    • 2018
  • Objectives: The purpose of this study was to confirm the relationship between socioeconomic characteristics and the prevalence of periodontal disease, with a focus on employment status, in a representative sample of Korean adults aged 19-39 years. Methods: Data were obtained from 3,178 adults who completed the Korean National Health and Nutrition Examination Survey, health-related questionnaires, and an oral examination. Socioeconomic, demographic, and oral health-related behavior data were adopted as independent variables. The chi-square test was used to assess differences in the distribution of socioeconomic status, oral health behavior, and nutrition factors according to employment status. Logistic regression analysis was performed to confirm the relationships between the prevalence of periodontitis and the related variables. Results: Significant differences in sex, educational level, income, marital status, smoking status, prevalence of periodontitis, number of dental check-ups in a year, and unmet dental care were confirmed according to employment status. The prevalence of periodontal disease was not significantly related to employment status. Conclusions: These results suggest a significant difference in periodontal disease according to socioeconomic factors in Korean adults. However, the prevalence of periodontal disease was not related to employment status. To prevent the progression of periodontal disease, attention should be paid to oral health, time available for dental treatment, smoking cessation, and use of floss.

Ovarian Cancers in 2 Dogs (개에서의 난소종양 2예)

  • 정성목;이충호;김완희;양정환;김대용;최민철;윤정희;이주명;권오경
    • Journal of Veterinary Clinics
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    • v.18 no.4
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    • pp.438-441
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    • 2001
  • Two female Yorkshire terrier was referred to Veterinary Medical Teaching Hospital, Seoul National University. In case 1, clinical signs were vomiting, anorexia and weight loss. Cystic intraabdominal mass was identified in radiographic and ultrasonographic examination. In case 2, clinical sign was abdominal distension. In radiographic and ultrasonographic examination, cellular ascites and bilateral intraabdominal masses next to kidneys were observed. Many clusters of glandular epithelial cells with anisocytosis, anisokaryosis, high N:C ratio coarse chromatin and prominent nucleoli were shown in cytologic examination of sanguineous ascites. In all two cases exploratory laparotomy was performed and enlarged ovaries were observed (Rt: 6$\times$5$\times$5 cm and Lt: 3$\times$2$\times$1 cm in case 1 and 3$\times$2$\times$1 cm bilaterally in case 2). After ovariohysterectomy histopathologic examinations were performed. Histopathologically the masses were diagnosed as ovarian adenocarcinoma and ovarian cystadenocarcinoma in case 1 and case 2, respectively. In both dogs no further chemotherapy was carried out. These two dogs had no gross evidence of tumor recurrence at the time of 3 months after tumor resection, but long-term follow-up might be needed.

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A Study of Automation for Examination Analysis of Inservice Inspection for Nuclear Power Plant (I) (원자력발전소(原子力發電所) 가동중(稼動中) 검사(檢査)의 시험분석(試驗分析)을 위한 자동화연구(自動化硏究) (I))

  • Kim, W.
    • Journal of the Korean Society for Nondestructive Testing
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    • v.5 no.1
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    • pp.34-47
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    • 1985
  • The developing country, KOREA where does not possess the natural resources for traditional energy such as oil and gas, so. The nuclear energy is the most single reliable source available for closing the energy gap. For these reason, It is inavoidable to construct the nuclear power plant and to develop technology related nuclear energy. The rate of operation in large nuclear power facilities depends upon the performance of work system through design and construction, and also the applied technology. Especially, it is the most important element that safety and reliability in operation of nuclear power plant. In view of this aspects, Nuclear power plant is performed severe examinations during preservice and inservice inspection. This study provide an automation of analysis for volumetric examination which is required to nuclear power plant components. It is composed as follows: I. Introduction II. Inservice Inspection of Nuclear Power Plant ${\ast}$ General Requirement. ${\ast}$ Principle and Methods of Ultrasonic Test. ${\ast}$ Study of Flaw Evaluation and Design of Classifying Formula for Flaws. III. Design of Automation for Flaw Evaluation. IV. An Example V. Conclusion In this theory, It is classifying the flaws, the formula of classifying flaws and the design of automation that is the main important point. As motioned the above, Owing to such as automatic design, more time could be allocated to practical test than that of evaluation of defects, Protecting against subjective bias tester by himself and miscalculation by dint of various process of computation. For the more, adopting this method would be used to more retaining for many test data and comparative evaluating during successive inspection intervals. Inspite of limitation for testing method and required application to test components, it provide useful application to flow evaluation for volumetric examination. Owing to the characteristics of nuclear power plant that is highly skill intensive industry and has huze system, the more notice should be concentrated as follows. Establishing rational operation plan, developing various technology, and making the newly designed system for undeveloped sector.

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A System for the Selection of the Optimum Tower Cranes(Opt-TC) (건설현장의 조건을 고려한 최적 타워크레인 선정시스템)

  • Ho, Jonh-Kwan;Kim, Sun-Kuk;Kook, Dong-Hoon
    • Korean Journal of Construction Engineering and Management
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    • v.8 no.6
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    • pp.216-226
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    • 2007
  • The efficient vertical lift planning has been brought into relief in high-rise building construction projects. Particularly, the selection and stability examination of the tower cranes is the most important elements in vertical lift planning. Therefore, professional knowledge is needed to full fill the site condition for the plan. However, there are short of the number of specialists and information about tower cranes. This study proposes a system for the selection of the optimum tower cranes (Opt-TC) in high-rise building construction projects. The Opt-TC can give the selection and stability examination of tower cranes at once in real-time.